Protección de datos médicos e Internet

This report presents a discussion of the adventages electronic clinical data gives, not only to the medical staff (helping them to get more accurate data about their patients) but also to the patient (receiving a better medical care). Then we present a study of the current spanish and european laws that rule about protection of medical data. Finally we present the characteristics a distributed information system managing and storing medical data should have, and the security measures to be taken if such a system is connected to a public network such as Internet.Postprint (published version

UCTx: a multi-agent system to assist a transplant coordination unit

We present a system called UCTx, designed to model and automate some of the tasks performed by a Transplant Coordination Unit (UCTx) inside a Hospital. The aim of this work is to show how a multi-agent approach allows us to describe and implement the model, and how UCTx is capable of dealing with another multi-agent (Carrel, an Agent Mediated Institution for the exchange of Human Tissues among Hospitals for Transplantation) in order to meet its own goals, acting as the representative of the hospital in the negotiation. As an example we introduce the use of this Agency in the case of Cornea Transplantation.Postprint (published version

Extending the Carrel system to mediate in the organ and tissue allocation processes: a first approach

In this paper we extend the formalization of Carrel, a virtual organization for the procurement of tissues for transplantation purposes, in order to model also the procurement of human organs for transplants. We will focus in the organ allocation process to show how it can be formalized with the ISLANDER formalism. Also we present a first mechanism to federate the institution in several geographically-distributed platforms.Postprint (published version

Las misiones de los dominicos en la provincia de Chiapa. Transcripción del auto “Sobre que los religiosos de Santo Domingo, provean de suficientes ministros para las doctrinas que administran. Año de 1656”

The arrival of the order of Santo Domingo in Ciudad Real in 1545, today San Cristóbal de Las Casas, marked an important moment in the history of the province of Chiapa. During the colonial period, one of the Church’s constant concerns was the administration of important tenets for the Christianization of the Indians.La llegada, en 1545, de la orden de Santo Domingo a Ciudad Real, hoy San Cristóbal de Las Casas, marcó una importante coyuntura para la historia de la provincia de Chiapa. Durante el periodo colonial una de las constantes preocupaciones de la Iglesia fue la administración de importantes pilares para la cristianización de los indios

“Tan asqueroso y obsceno que aun el mismo Demonio… huye de ellos”. Control y Sodomía en la Provincia de Chiapa, siglos XVII-XVIII.

Along with the conquest and colonization, the diverse sexual practices of the Mesoamerican people were reduced to the epitome of sin. Under the prohibition, they established punishments against sexual dissidences that didn´t align to the Christian moral. Founded in these first notes, the text submitted is an approximation to the history of sodomy, regarding control, relationships and representations established during this period. This are described and analyzed on the basis of chronicles and colonial sources that we have located in some of the archives of México, Chiapas and Guatemala, with the main purpose of extending the observations regarding the intrusion of the civil and religious authorities in the sexual affairsCon la conquista y colonización, las   diversas prácticas sexuales de los pueblos mesoamericanos se redujeron al epítome de pecado. Bajo la prohibición se castigaron aquellas expresiones que no se alineaban a la moral cristiana. Fundamentado en estas primeras notas, el presente texto es una aproximación a la historia de la sodomía, a propósito del control, las relaciones y representaciones, establecidas durante este periodo. Estas son descritas y analizadas a partir de crónicas y fuentes coloniales que hemos localizado en algunos archivos de México, Chiapas y Guatemala, con el objetivo de prolongar la observación en la intromisión y trato de las autoridades civiles y religiosas a los asuntos relacionados con la sexualidad

USO DE BORTEZOMIB, TALIDOMIDA Y DEXAMETASONA, COMO TERAPIA DE PRIMERA LÍNEA EN PACIENTES CON MIELOMA MÚLTIPLE DE RECIENTE DIAGNÓSTICO. CENTRO MÉDICO ISSEMYM. ARTURO MONTIEL ROJAS

El Mieloma Múltiple (MM) es una neoplasia maligna hematológica caracterizada por una proliferación clonal no controlada de células plasmáticas, las cuales producen una paraproteína monoclonal. El Mieloma Múltiple puede condicionar lesiones líticas, falla renal, hipercalcemia, Síndrome de Hiperviscosidad y una inmunodeficiencia, la cual es agravada por los esquemas terapéuticos ofrecidos en esta enfermedad. Según las escalas pronosticas más utilizadas a nivel mundial, la sobrevida global esperada en el mejor de los casos es de 4 años, la cual puede ser menor en los casos de estadios avanzados de la enfermedad. En la mayoría de las ocasiones, esta enfermedad es incurable y los pacientes terminan complicándose con procesos infecciosos que condicionan la muerte al enfermo

Multi-objective models for the forest harvest scheduling problem in a continuous-time framework

In this study we present several multi-objective models for forest harvest scheduling in forest with single-species, even-aged stands using a continuous formulation. We seek to maximize economic profitability and even-flow of timber harvest volume, both for the first rotation and for the regulated forest. For that, we design new metrics that allow working with continuous decision variables, namely, the harvest time of each stand. Unlike traditional combinatorial formulations, this avoids dividing the planning horizon into periods and simulating alternative management prescriptions before the optimization process. We propose to combine a scalarization technique (weighting method) with a gradient-type algorithm (L-BFGS-B) to obtain the Pareto frontier of the problem, which graphically shows the relationships (trade-offs) between objectives, and helps the decision makers to choose a suitable weighting for each objective. We compare this approach with the widely used in forestry multi-objective evolutionary algorithm NSGA-II. We analyze the model in a Eucalyptus globulus Labill. forest of Galicia (NW Spain). The continuous formulation proves robust in forests with different structures and provides better results than the traditional combinatorial approach. For problem solving, our proposal shows a clear advantage over the evolutionary algorithm in terms of computational time (efficiency), being of the order of 65 times faster for both continuous and discrete formulationsS

Forecasting variations in profitability and silviculture under climate change of radiata pine plantations through differentiable optimization

Climate change might entail significant alterations in future forest productivity, profitability and management. In this work, we estimated the financial profitability (Soil Expectation Value, SEV) of a set of radiata pine plantations in the northwest of Spain under climate change. We optimized silvicultural interventions using a differentiable approach and projected future productivity using a machine learning model basing on the climatic predictions of 11 Global Climate Models (GCMs) and two Representative Concentration Pathways (RCPs). The forecasted mean SEV for future climate was lower than current SEV (∼22% lower for RCP 4.5 and ∼29% for RCP 6.0, with interest rate = 3%). The dispersion of the future SEV distribution was very high, alternatively forecasting increases and decreases in profitability under climate change depending on the chosen GCM. Silvicultural optimization considering future productivity projections effectively mitigated the potential economic losses due to climate change; however, its ability to perform this mitigation was strongly dependent on interest rates. We conclude that the financial profitability of radiata pine plantations in this region might be significantly reduced under climate change, though further research is necessary for clearing the uncertainties regarding the high dispersion of profitability projectionsS