3,816 research outputs found
Rotor redesign for a highly loaded 1800 ft/sec tip speed fan. 1: Aerodynamic and mechanical design report
A quasi three dimensional design system and multiple-circular-arc airfoil sections were used to design a fan rotor. An axisymmetric intrablade flow field calculation modeled the shroud of an isolated splitter and radial distribution. The structural analysis indicates that the design is satisfactory for evaluation of aerodynamic performance of the fan stage in a test facility
A definição dos idosos de qualidade de vida
OBJECTIVES: Senescence for some elderly people is a phase of with development and satisfaction, whereas for others is a negative stage of life. The determinants of a good quality of life in old age vary from person to person. The aims of this study were to identify: 1) the prevalence of octogenarian people who evaluate their current life as being mainly characterized by a positive quality and 2) which were the domains that they identified as being the determinants of this positive quality. A same parallel study was conducted with subjects who evaluated senescence as a preponderantly negative experience. METHODS: A random and representative sample of 35% of the octogenarian people, living residing in the community, was selected among the dwellers of the city of Veranópolis, state of Rio Grande do Sul. A semi-structured questionnaire on quality of life quality was applied as well as the scale of depressive symptoms Geriatric Depression Scale (GDS) and the index of general health Cumulative Illness Rating Scale (CIRS). RESULTS: Slightly more than half of the studied sample (57%) defined their current quality of life with positive evaluations, whereas 18% presented a negative evaluation of it. A group 0f 25% defined their current lives as neutral or having both values (positive and negative). Those who were dissatisfied presented more health problems according to the CIRS and more depressive symptoms when evaluated by the GDS. Satisfied subjects ones had different reasons to justify this state, however, the dissatisfied had mainly the lack of health as a reason for their suffering. The main source of reported daily well-being was the involvement with rural or domestic activities. Among the interviewed, lack of health was the main source for not presenting well-being, although there was interpersonal variability regarding what each subject considered as loss of health. CONCLUSION: Possibly, for the elderly subjects a negative quality of life is equivalent to loss of health and a positive life quality is equivalent to a greater range of categories such as activity, income, social life and relationship with the family, categories which differed from subject to subject. Therefore, health seems to be a good indicator of negative quality of life, though an insufficient indicator of successful elderliness.OBJETIVOS: A velhice para alguns é uma etapa de desenvolvimento e satisfação, enquanto para outros é uma fase negativa da vida. Os determinantes da boa qualidade de vida na velhice variam de sujeito para sujeito. O objetivo do presente estudo foi identificar: 1) a prevalência de octagenários que avaliavam sua vida atual na velhice como preponderantemente de uma qualidade positiva e 2) quais aspectos eles identificavam como os determinantes desta qualidade positiva. Igual estudo em paralelo foi feito com sujeitos que avaliavam a velhice como uma experiência preponderantemente negativa. MÉTODOS: Uma amostra randômica e representativa de 35% dos idosos com mais de 80 anos residentes na comunidade foi selecionada entre os residentes em Veranópolis, Rio Grande do Sul. Um questionário semi- estruturado de qualidade de vida foi aplicado, bem como a escala de sintomas depressivos Geriatric Depression Scale (GDS) e o Índice de Saúde Geral Cumulative Illness Rating Scale (CIRS). RESULTADO: Um pouco mais da metade dos idosos estudados (57%) definia sua qualidade de vida atual com avaliações positivas, sendo que 18% tinham uma avaliação negativa da vida atual. Um grupo de 25% definia sua vida atual de forma neutra ou de dois valores (aspectos positivos e aspectos negativos). Comparados com os satisfeitos, os insatisfeitos tinham mais problemas de saúde pela CIRS e mais sintomas depressivos quando avaliados pela GDS. Os satisfeitos tinham diferentes motivos para justificar este estado, porém os insatisfeitos tinham principalmente a falta de saúde física como motivo do sofrimento. A maior fonte de bem estar no dia-a-dia citada era o envolvimento com atividades rurais ou domésticas. Entre os entrevistados, a perda da saúde física era a principal fonte de mal estar, sendo que havia variabilidade interpessoal quanto ao que cada sujeito considerava como perda de saúde. CONCLUSÃO: É possível que para idosos, qualidade negativa de vida seja equivalente a perda de saúde e qualidade de vida positiva seja equivalente a uma pluralidade maior de categorias como atividade, renda, vida social e relação com a família, categorias diferentes de sujeito para sujeito. O aspecto saúde parece assim um bom indicador de qualidade de vida negativa, porém um indicador insuficiente de velhice bem sucedida.Catholic University of the state of Rio Grande do Sul Institute of Geriatrics and Gerontology Geriatric neuropsychiatric ambulatoryWHO PAHO Associated Chronic Degenerating DiseasesFederal University of São Paulo Paulista Medical School Department of PsychiatryPUCRS Medical School Department of PsychiatryUNIFESP, EPM, Department of PsychiatrySciEL
Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones
In this study, we elucidate the roles of the winged-helix transcription factor Foxa2 in ventral CNS development in zebrafish. Through cloning of monorail (mol), which we find encodes the transcription factor Foxa2, and phenotypic analysis of mol(-/-) embryos, we show that floorplate is induced in the absence of Foxa2 function but fails to further differentiate. In mol(-/-) mutants, expression of Foxa and Hh family genes is not maintained in floorplate cells and lateral expansion of the floorplate fails to occur. Our results suggest that this is due to defects both in the regulation of Hh activity in medial floorplate cells as well as cell-autonomous requirements for Foxa2 in the prospective laterally positioned floorplate cells themselves. Foxa2 is also required for induction and/or patterning of several distinct cell types in the ventral CNS. Serotonergic neurones of the raphe nucleus and the trochlear motor nucleus are absent in mol(-/-) embryos, and oculomotor and facial motoneurones ectopically occupy ventral CNS midline positions in the midbrain and hindbrain. There is also a severe reduction of prospective oligodendrocytes in the midbrain and hindbrain. Finally, in the absence of Foxa2, at least two likely Hh pathway target genes are ectopically expressed in more dorsal regions of the midbrain and hindbrain ventricular neuroepithelium, raising the possibility that Foxa2 activity may normally be required to limit the range of action of secreted Hh proteins
Does Quantum Mechanics Clash with the Equivalence Principle - and Does it Matter?
With an eye on developing a quantum theory of gravity, many physicists have
recently searched for quantum challenges to the equivalence principle of
general relativity. However, as historians and philosophers of science are well
aware, the principle of equivalence is not so clear. When clarified, we think
quantum tests of the equivalence principle won't yield much. The problem is
that the clash/not-clash is either already evident or guaranteed not to exist.
Nonetheless, this work does help teach us what it means for a theory to be
geometric.Comment: 12 page
Optical Detection of a Single Nuclear Spin
We propose a method to optically detect the spin state of a 31-P nucleus
embedded in a 28-Si matrix. The nuclear-electron hyperfine splitting of the
31-P neutral-donor ground state can be resolved via a direct frequency
discrimination measurement of the 31-P bound exciton photoluminescence using
single photon detectors. The measurement time is expected to be shorter than
the lifetime of the nuclear spin at 4 K and 10 T.Comment: 4 pages, 3 figure
A survey of cost-sensitive decision tree induction algorithms
The past decade has seen a significant interest on the problem of inducing decision trees that take account of costs of misclassification and costs of acquiring the features used for decision making.  This survey identifies over 50 algorithms including approaches that are direct adaptations of accuracy based methods, use genetic algorithms, use anytime methods and utilize boosting and bagging.  The survey brings together these different studies and novel approaches to cost-sensitive decision tree learning, provides a useful taxonomy, a historical timeline of how the field has developed and should provide a useful reference point for future research in this field
The SuperWASP catalogue of 4963 RR Lyr stars: identification of 983 Blazhko candidates
Aims. We set out to compile a catalogue of RRab pulsating variables in the SuperWASP archive and identify candidate Blazhko effect objects within this catalogue. We analysed their light curves and power spectra for correlations in their common characteristics to further our understanding of the phenomenon. Methods. Pulsation periods were found for each SWASP RRab object using PDM techniques. Low frequency periodic signals detected
in the CLEAN power spectra of RRab stars were matched with modulation sidebands and combined with pairs of sidebands to produce a list of candidate Blazhko periods. A novel technique was used in an attempt to identify Blazhko effect stars by comparing scatter at different parts of the folded light curve. Pulsation amplitudes were calculated based on phase folded light curves.Results. The  SuperWASP  RRab  catalogue  consists  of  4963 objects of which 3397  are previously unknown.  We discovered 983 distinct candidates for Blazhko effect objects, 613 of these being previously unknown in the literature as RR Lyrae stars, and 894 are previously unknown to be Blazhko effect stars. Correlations were investigated between the scatter of points on the light curve, the periods and amplitudes of the objects’ pulsations, and those of the Blazhko effect.Conclusions. A statistical analysis has been performed on a large population of Blazhko effect stars from the wide-field SuperWASP survey. No correlations were found between the Blazhko period and other parameters including the Blazhko amplitude, although we confirmed a lower rate of occurrence of the Blazhko effect in long pulsation period objects
Nonlocal Effects and Shrinkage of the Vortex Core Radius in YNi2B2C Probed by muSR
The magnetic field distribution in the vortex state of YNi2B2C has been
probed by muon spin rotation (muSR). The analysis based on the London model
with nonlocal corrections shows that the vortex lattice has changed from
hexagonal to square with increasing magnetic field H. At low fields the vortex
core radius, rho_v(H), decreases with increasing H much steeper than what is
expected from the sqrt(H) behavior of the Sommerfeld constant gamma(H),
strongly suggesting that the anomaly in gamma(H) primarily arises from the
quasiparticle excitations outside the vortex cores.Comment: 4 pages, 4 figures, submitted to Phys. Rev. 
Coronal properties of the EQ Peg binary system
The activity indicators of M dwarfs are distinctly different for early and
late types. The coronae of early M dwarfs display high X-ray luminosities and
temperatures, a pronounced inverse FIP effect, and frequent flaring to the
extent that no quiescent level can be defined in many cases. For late M dwarfs,
fewer but more violent flares have been observed, and the quiescent X-ray
luminosity is much lower. To probe the relationship between coronal properties
with spectral type of active M dwarfs, we analyze the M3.5 and M4.5 components
of the EQ Peg binary system in comparison with other active M dwarfs of
spectral types M0.5 to M5.5. We investigate the timing behavior of both
components of the EQ Peg system, reconstruct their differential emission
measure, and investigate the coronal abundance ratios based on emission-measure
independent line ratios from their Chandra HETGS spectra. Finally we test for
density variations in different states of activity. The X-ray luminosity of EQ
Peg A (M3.5) is by a factor of 6-10 brighter than that of EQ Peg B (M4.5). Like
most other active M dwarfs, the EQ Peg system shows an inverse FIP effect. The
abundances of both components are consistent within the errors; however, there
seems to be a tendency toward the inverse FIP effect being less pronounced in
the less active EQ Peg B when comparing the quiescent state of the two stars.
This trend is supported by our comparison with other M dwarfs. As the X-ray
luminosity decreases with later spectral type, so do coronal temperatures and
flare rate. The amplitude of the observed abundance anomalies, i.e. the inverse
FIP effect, declines; however, clear deviations from solar abundances remain.Comment: 14 pages, accepted by A&
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