Imaginario Social de la Colaboración: Voluntariado y Solidaridad

The reaches of collaboration, though is not a highly thematized concept in the modern world, it is present in our practices and discourses. This paper displays the shapes that social collaboration assumes in daily communication, based on the discourses of those who exercise volunteer work (collaboration in its most visible and practical form).Los alcances de la colaboración, aunque no es un concepto altamente tematizado en el mundo moderno, subyacen a nuestras prácticas y discursos. Esta ponencia muestra las formas que asume la colaboración social en la comunicación cotidiana, basándonos en los discursos de aquellos que ejercen voluntariado (colaboración en su forma más visible y práctica)

Programación didáctica - Tecnología, programación y robótica 1º ESO

Máster Universitario en Formación del Profesorado de ESO, Bachillerato, Formación Profesional y Enseñanza de Idiomas. Especialidad en Tecnología (M090

La Realidad de lo Improbable: Colaboración, una manifestación social marginal

Contemporary society observes itself as a society in crisis, where individualism is weakening the social bonds. However, we can find important facts of collaborative actions. In this paper we lay out this apparent contradiction and we intend to develop theoretical devices to observe it.La sociedad contemporánea se observa a sí misma como una sociedad en crisis, donde el individualismo estaría debilitando los vínculos sociales. Sin embargo, podemos encontrar importantes manifestaciones de acciones colaborativas. En este artículo problematizamos esta aparente contradicción e intentamos desarrollar herramientas teóricas para observarla

Propuesta de Mejora sobre la Didáctica del Límite de una Función en el Aula

El presente Trabajo Fin de Máster, trata sobre el análisis, reflexión y propuesta de mejora de la unidad didáctica: Límite de una función. Continuidad y Asíntotas; desarrollada en el aula de 1º de Bachillerato de Ciencias Sociales, del IES Paterna; durante el segundo período de prácticas del Máster Oficial de Profesorado en Educación Secundaria Obligatoria y Bachillerato, en la especialidad de Matemáticas. Para ello, se tendrán en cuenta los conocimientos adquiridos en los distintos módulos del Máster, así como las vivencias aportadas por las propias prácticas. A la hora de incluir las mejoras a la unidad se han tenido dos objetivos claros: por un lado la motivación del alumnado y por otro, hacerles más autónomos y evitar que dependan de las clases particulares, sobre todo teniendo en cuenta el bajo nivel económico de las familias. Por ello, se incluirán diversas estrategias metodológicas y recursos innovadores, tanto nuevos, como algunos ya previstos en la unidad didáctica original; pero que no he podido desarrollar en el aula durante el período de prácticas, como son: la historia, clases invertidas, uso de las Tics, aprendizaje cooperativo, trabajo en grupo y uso de juegos.274 página

EBTs en España: tipos de EBTs y su impacto en la productividad

Las Empresas de Base Tecnológica (EBTs) vienen recibiendo una atención creciente por parte de la literatura académica, consciente de su importancia para el progreso técnico, la mejora de la productividad y el crecimiento económico. No obstante, la investigación al respecto adolece de falta de consenso en torno al propio concepto de EBT. Distintos trabajos emplean diferentes criterios, en muchas ocasiones guiados más por cuestiones de conveniencia y disponibilidad de datos que por argumentos teóricos. El presente trabajo revisa dichos criterios y, utilizando herramientas tomadas de la teoría de conjuntos, los combina para construir una tipología que recoge diferentes configuraciones de empresas, principalmente en función de su relación con la tecnología. Esta metodología nos permite explorar en detalle la heterogeneidad existente dentro de las EBTs, concepto que puede dar cobijo a tipos de empresas muy diferentes, y llevar a cabo un análisis causal, identificando las configuraciones de empresas que conducen a la obtención de una elevada productividad. Para el análisis empleamos datos procedentes del PITEC (2007)

Effects of Methyl Jasmonate and Nano-Methyl Jasmonate Treatments on Monastrell Wine Volatile Composition

This work has been supported by funding provided by the Spanish MCIN/AEI/10.13039/501100011033 and "ERDF, A way of making Europe" through the projects NanoVIT (RTI-2018-095794-B-C21 and RTI-2018-095794-A-C22), and by the Junta de Andalucia with the project NanoFERTi (P18-TP-969). GBRR also acknowledges Junta de Andalucia for her postdoctoral contract within the PAIDI 2020 program (DOC_01383).The application of methyl jasmonate (MeJ) as an elicitor to enhance secondary metabolites in grapes and wines has been studied, but there is little information about its use in conjunction with nanotechnology and no information about its effects on wine volatile compounds. This led us to study the impact of nanoparticles doped with MeJ (Nano-MeJ, 1mM MeJ) on the volatile composition of Monastrell wines over three seasons, compared with the application of MeJ in a conventional way (10 mM MeJ). The results showed how both treatments enhanced fruity esters in wines regardless of the vintage year, although the increase was more evident when grapes were less ripe. These treatments also achieved these results in 2019 in the cases of 1-propanol, ß-phenyl-ethanol, and methionol, in 2020 in the cases of hexanol and methionol, and in 2021, but only in the case of hexanol. On the other hand, MeJ treatment also increased the terpene fraction, whereas Nano-MeJ, at the applied concentration, did not increase it in any of the seasons. In summary, although not all families of volatile compounds were increased by Nano-MeJ, the Nano-MeJ treatment generally increased the volatile composition to an extent similar to that obtained with MeJ used in a conventional way, but at a 10 times lower dose. Therefore, the use of nanotechnology could be a good option for improving the quality of wines from an aromatic point of view, while reducing the necessary dosage of agrochemicals, in line with more sustainable agricultural practices.Junta de Andalucia P18-TP-969 DOC_01383Spanish MCIN/AEI"ERDF, A way of making Europe" through the projects NanoVIT RTI-2018-095794-B-C21 RTI-2018-095794-A-C2

Documentación VII. Mandato negociador para el Tratado entre el Reino Unido y la Unión Euroepa con respecto a Gibraltar, 5 de octubre de 2021

Documentació

GC gene polymorphism and unbound serum retinol-binding protein 4 are related to the risk of insulin resistance in patients with chronic hepatitis c: A prospective cross-sectional study

Insulin resistance (IR) is found in chronic hepatitis C (CHC) more frequently than in other chronic liver diseases. Prospective cross-sectional study to evaluate a wide multitest panel to identify factors related with IR in CHC and their possible interactions. In 76 patients with CHC we performed a series of routine laboratory analysis as well as specifically designed serum biochemical tests [retinol, retinol-binding protein 4 (RBP4), 25-OH vitamin D, Vitamin E, lipopolysaccharide-binding protein (LBP), interleukin-6 (IL-6), and cystatin C]. The single nucleotide polymorphisms rs7041 and rs4588 GC-DBP (group-specific component-Vitamin D-binding protein), rs738409 PNPLA3 (patatin-like phospholipase domain containing 3), and rs12979860 IL28B (interleukin-28 B) genes were determined. Insulin sensitivity was established with the HOMA-IR and IR was diagnosed when HOMA-IR>3. Fibrosis staging was assessed with liver biopsy or transient elastography. After backward logistic regression analysis, independent variables associated with IR were Gc1s/Gc1s DBP phenotype, that results from the homozygous carriage of the rs7041G/rs4588Chaplotype (P¼0.033); low retinol/RBP4 ratio, reflecting a greater rate of unboundRBP4 (P¼0.005); older age (P¼0.01); high serum tryglicerides (P¼0.026); and advanced (F3–F4) fibrosis stage. The AUROC provided by the multivariate model was 0.950 (95% CI¼0.906–0.993). In addition to previously known ones, the Gc1s/Gc1s phenotype variant of DBP and the unbound fraction of plasma RBP4 may be considered as factors related with the incidence, and possibly the risk, of IR in CHC patients.• Instituto de Salud Carlos III, Fondo de Investigación Sanitari: Ayudas PI12/00241 y PI12/00324 • Junta de Extremadura: Ayuda GR15026 • Fondos FEDERpeerReviewe

Electromagnetic emission analysis of a multiband EMI filter based on sub-wavelength resonators

In this paper the electromagnetic emission of sub-wavelength EMI filter based on SRR and CSRR resonator has been analysed by means of near E and H fields simulation with the FDTD SEMCAD® software. The target bands are 900 MHz (RFID UHF), 1.8 GHz (GSM) and 2.4 GHz (ISM, Instrumentation, Scientific and Medical). A 3-stages/5-stages rejection band filter was designed and fabricated in a PCB. The preliminary simulation results show that the more significant emissions take place at higher frequencies, the 1.8 GHz GSM band and ISM band (2.4 GHz), and are located at the resonators’ surface.Peer ReviewedPostprint (author's final draft

The contribution of fenfluramine to the treatment of Dravet syndrome in Spain through Multi-Criteria Decision Analysis

Introduction: Dravet Syndrome (DS) is a severe, developmental epileptic encephalopathy (DEE) that begins in infancy and is characterized by pharmaco-resistant epilepsy and neurodevelopmental delay. Despite available antiseizure medications (ASMs), there is a need for new therapeutic options with greater efficacy in reducing seizure frequency and with adequate safety and tolerability profiles.Fenfluramine is a new ASM for the treatment of seizures associated with DS as add-on therapy to other ASMs for patients aged 2 years and older. Fenfluramine decreases seizure frequency, prolongs periods of seizure freedom potentially helping to reduce risk of Sudden Unexpected Death in Epilepsy (SUDEP) and improves patient cognitive abilities positively impacting on patients' Quality of Life (QoL).Reflective Multi-Criteria Decision Analysis (MCDA) methodology allows to determine what represents value in a given indication considering all relevant criteria for healthcare decision-making in a transparent and systematic manner from the perspective of relevant stakeholders. The aim of this study was to determine the relative value contribution of fenfluramine for the treatment of DS in Spain using MCDA.Method: A literature review was performed to populate an adapted a MCDA framework for orphan-drug evaluation in Spain. A panel of ten Spanish experts, including neurologists, hospital pharmacists, patient representatives and decision-makers, scored four comparative evidence matrices.Results were analyzed and discussed in a group meeting through reflective MCDA discussion methodology. Results: Dravet syndrome is considered a severe, rare disease with significant unmet needs. Fenfluramine is perceived to have a higher efficacy profile than all available alternatives, with a better safety profile than stiripentol and topiramate and to provide improved QoL versus studied alternatives. Fenfluramine results in lower other medical costs in comparison with stiripentol and clobazam. Participants perceived that fenfluramine could lead to indirect costs savings compared to available alternatives due to its efficacy in controlling seizures. Overall, fenfluramine's therapeutic impact on patients with DS is considered high and supported by high-quality evidence.Conclusions: Based on reflective MCDA, fenfluramine is considered to add greater benefit in terms of effi-cacy, safety and QoL when compared with available ASMs.(c) 2022 The Authors. Published by Elsevier Inc