TIC y gestión hospitalaria en el distrito de Saposoa, 2022

La investigación tuvo como objetivo determinar la relación entre las TIC y gestión hospitalaria en el distrito de Saposoa, 2022. La investigación fue tipo básica, diseño no experimental, transversal y descriptivo correlacional, cuya población y muestra fue de 113 trabajadores. La técnica de recolección de datos fue la encuesta y como instrumento el cuestionario. Los resultados determinaron que el nivel de las TIC, fue medio en 71 %, bajo en 18 % y alto en 11 %; la gestión hospitalaria, fue regular en 47 %, malo en 35 % y bueno en 18 %. Concluyendo que existe relación significativa entre las TIC y gestión hospitalaria en el distrito de Saposoa, 2022, ya que el análisis estadístico de Rho de Spearman fue de 0, 967 (correlación positiva muy alta) y un p valor igual a 0,000 (p-valor ≤ 0.01); además, solo el 93.51 % de las TIC influye en la gestión hospitalari

New Method for Complex Network Reliability Analysis through Probability Propagation

Reliability analysis of complex networks is often limited by increasing dimensionality of the problem as the number of nodes and possible paths in the network increases. This is true particularly for reliability analysis problems that exponentially increase in computational requirements with system size. In this paper, we present a new method for complex network reliability analysis. We call this the probability propagation method (PrPm). The idea originates from the concept of belief propagation for inference in network graphs. In PrPm, the message passed between nodes is a joint probability distribution. At each step, the distribution is updated and passed as the message to its direct neighbors. After the message passes to the terminal node, an estimation of the network reliability is found. The method results in an analytical solution for system reliability. We present the derived updating rules for message passing and apply the method to two test applications: a system distribution network and general grid network. In the message passing, some approximations are made. Results from the applications show high accuracy for the proposed method compared to exact solutions where possible for comparison. In addition, PrPm achieves orders of magnitude increases in computational efficiency compared to existing approaches. This includes reducing the computational cost for analyses from an exponential increase in computation time with the size of the system to a quartic increase. The method enables the accurate and computationally tractable calculation of failure probabilities of large, generally connected systems

Determinación del momento óptimo del beneficio o saca en el engorde de ovinos de la raza pelibuey en el trópico de San Martín

The quality of the soils and its uneven physiography that determines its good drainage, as well as the weather, have made the hair ovine prosper and spread in the region. San Martin has the highest population of “Pelibuey” ovine (25 000 head), in comparison to other rainforest areas. Nevertheless, the ovine breeding isn’t an attractive activity yet, due to the low demand in the market, caused by the lack of awareness of people about the consumption of the meat. There is also a prejudice, that rejects it due to its smell and taste (“aftertaste”), and the lack of technology that improves the productivity, these have determined that it is an activity with low profitability. It is important to revert this situation looking for a practical alternative, as the “FATTENING OF YOUNG OVINE”, for the production of meat, activity that will also allow to mobilize the internal market of the ovine breeding, increasing its consumption and demand, improving their profitability, and thus turning it into an important agriculture and livestock activity that would benefit the rural producer, increasing his income; and the rural and urban settlers, who would have another source of protein. This document was made with the aim of evaluating, in a 60-day period, five feeding programs to fatten young ovine: Free grazing and night confinement (T0), Stabling with grass + rice bran (T1), Stabling with grass + chopped leguminous (T2), Stabling with balanced food (T3), and Stabling with grass + balanced food (T4). The obtained results report better productive behaviors for the treatment T0, followed by the treatment T3, after treatment T2, and finally T1, so we can conclude that the fattening of ovine is more efficient when the grazing is carried outLa calidad de los suelos y su fisiografía accidentada, que determinan su buen drenaje, así como el clima, han hecho que el ovino de pelo prospere y se difunda por la región, siendo San Martín la que cuenta con la más alta población de ovinos “Pelibuey” (25 000 cabezas), en relación a las demás regiones de selva. Sin embargo la crianza de ovinos no se ha constituido todavía en una actividad económicamente atractiva, por su baja demanda en el mercado, originado por el desconocimiento del consumo de ésta carne. La existencia de prejuicios que la rechazan por su olor y sabor (“tiene dejo”) y la falta de tecnología que mejore la productividad, ha determinado que sea una actividad con baja rentabilidad. Esta situación es necesario revertir, buscando alternativas prácticas, como lo es el “ENGORDE DE OVINOS JOVENES”, para la producción de carne, actividad que permitiría movilizar el mercado interno de la crianza de ovinos, incrementando su consumo, aumentando su demanda , mejorando su rentabilidad, en fin, convirtiéndola en una actividad agropecuaria importante, que beneficiaría al productor rural, al aumentar sus ingresos; al poblador rural y urbano, quienes tendrían una fuente más de alimento proteico. El presente trabajo se efectuó con la finalidad de evaluar en un periodo de 60 días, cinco sistemas de alimentación para el engorde de ovinos jóvenes: Pastoreo libre y confinamiento en la noche (T0), Estabulado con pasto gramínea + polvillo de arroz (T1), Estabulado con pasto gramínea + leguminosa picado (T2), Estabulado con alimento balanceado (T3), y Estabulado con pasto gramínea + alimento balanceado (T4). Los resultados obtenidos, reportan mejores comportamientos productivos para el tratamiento testigo T0, seguido del tratamiento T3, luego el tratamiento T2, y finalmente el tratamiento T1, de lo que concluimos, que el engorde de ovinos es más eficiente, cuando se utiliza el pastoreoTesi

Evaluation of the ClearVoice Strategy in Adults Using HiResolution Fidelity 120 Sound Processing

ObjectivesThis study aimed to evaluate the benefits of ClearVoice strategy on speech perception in noise and in everyday listening situations in Cantonese-speaking cochlear implant users.MethodsTwelve experienced adult users of the Harmony implant and HiRes 120 sound processing participated in the study. The study employed a prospective within-subjects design wherein speech recognition in adults using HiRes 120 without ClearVoice turned on (control option) was compared to their performance with HiRes 120 with ClearVoice turned on. Each subject was evaluated with two different ClearVoice gain settings: -12 dB (ClearVoice medium) and -18 dB (ClearVoice high) after one-week of use. The Cantonese hearing in noise test and a questionnaire were used as the outcome measures.ResultsSubjects performed significantly better with ClearVoice medium than with control option in noise. No significant difference in performance was noted among the 3 settings in quiet. Most subjects reported high level of satisfaction with ClearVoice in daily listening situations and preferred to keep ClearVoice on.ConclusionClearVoice can help cochlear implant recipients to hear better in noise

Defect segregation and its effect on the photoelectrochemical properties of Ti-doped hematite photoanodes for solar water splitting

Optimising the photoelectrochemical performance of hematite photoanodes for solar water splitting requires better understanding of the relationships between dopant distribution, structural defects and photoelectrochemical properties. Here, we use complementary characterisation techniques including electron microscopy, conductive atomic force microscopy (CAFM), Rutherford backscattering spectroscopy (RBS), atom probe tomography (APT) and intensity modulated photocurrent spectroscopy (IMPS) to study this correlation in Ti-doped (1 cat.%) hematite films deposited by pulsed laser deposition (PLD) on F:SnO2 (FTO) coated glass substrates. The deposition was carried out at 300 {\deg}C, followed by annealing at 500 deg C for 2 h. Upon annealing, Ti was observed by APT to segregate to the hematite/FTO interface and into some hematite grains. Since no other pronounced changes in microstructure and chemical composition were observed by electron microscopy and RBS after annealing, the non-uniform Ti redistribution seems to be the reason for a reduced interfacial recombination in the annealed films, as observed by IMPS. This results in a lower onset potential, higher photocurrent and larger fill factor with respect to the as-deposited state. This work provides atomic-scale insights into the microscopic inhomogeneity in Ti-doped hematite thin films and the role of defect segregation in their electrical and photoelectrochemical properties

Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome

Background: Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically targeted by epigenetic (DNA methylation) signatures in the placenta. By comparing one such methylated fetal epigenetic marker located on chromosome 21 with another fetal genetic marker located on a reference chromosome in maternal plasma, we could infer the relative dosage of fetal chromosome 21 and noninvasively detect fetal trisomy 21. Here we apply this epigenetic-genetic (EGG) chromosome dosage approach to detect Edwards syndrome (trisomy 18) in the fetus noninvasively. Principal Findings: We have systematically identified methylated fetal epigenetic markers on chromosome 18 by methylated DNA immunoprecipitation (MeDIP) and tiling array analysis with confirmation using quantitative DNA methylation assays. Methylated DNA sequences from an intergenic region between the VAPA and APCDD1 genes (the VAPAAPCDD1 DNA) were detected in pre-delivery, but not post-delivery, maternal plasma samples. The concentrations correlated positively with those of an established fetal genetic marker, ZFY, in pre-delivery maternal plasma. The ratios of methylated VAPA-APCDD1(chr18) to ZFY(chrY) were higher in maternal plasma samples of 9 male trisomy 18 fetuses than those of 27 male euploid fetuses (Mann-Whitney test, P = 0.029). We defined the cutoff value for detecting trisomy 18 fetuses as mean+1.96 SD of the EGG ratios of the euploid cases. Eight of 9 trisomy 18 and 1 of 27 euploid cases showed EGG ratios higher than the cutoff value, giving a sensitivity of 88.9% and a specificity of 96.3%. Conclusions: Our data have shown that the methylated VAPA-APCDD1 DNA in maternal plasma is redominantly derived from the fetus. We have demonstrated that this novel fetal epigenetic marker in maternal plasma is useful for the noninvasive detection of fetal trisomy 18. © Tsui et al.published_or_final_versio

A 32-society investigation of the influence of perceived economic inequality on social class stereotyping

International audienceThere is a growing body of work suggesting that social class stereotypes are amplified when people perceive higher levels of economic inequality-that is, the wealthy are perceived as more competent and assertive and the poor as more incompetent and unassertive. The present study tested this prediction in 32 societies and also examines the role of wealth-based categorization in explaining this relationship. We found that people who perceived higher economic inequality were indeed more likely to consider wealth as a meaningful basis for categorization. Unexpectedly, however, higher levels of perceived inequality were associated with perceiving the wealthy as less competent and assertive and the poor as more competent and assertive. Unpacking this further, exploratory analyses showed that the observed tendency to stereotype the wealthy negatively only emerged in societies with lower social mobility and democracy and higher corruption. This points to the importance of understanding how socio-structural features that co-occur with economic inequality may shape perceptions of the wealthy and the poor

Shifting the limits in wheat research and breeding using a fully annotated reference genome

Introduction: Wheat (Triticum aestivum L.) is the most widely cultivated crop on Earth, contributing about a fifth of the total calories consumed by humans. Consequently, wheat yields and production affect the global economy, and failed harvests can lead to social unrest. Breeders continuously strive to develop improved varieties by fine-tuning genetically complex yield and end-use quality parameters while maintaining stable yields and adapting the crop to regionally specific biotic and abiotic stresses. Rationale: Breeding efforts are limited by insufficient knowledge and understanding of wheat biology and the molecular basis of central agronomic traits. To meet the demands of human population growth, there is an urgent need for wheat research and breeding to accelerate genetic gain as well as to increase and protect wheat yield and quality traits. In other plant and animal species, access to a fully annotated and ordered genome sequence, including regulatory sequences and genome-diversity information, has promoted the development of systematic and more time-efficient approaches for the selection and understanding of important traits. Wheat has lagged behind, primarily owing to the challenges of assembling a genome that is more than five times as large as the human genome, polyploid, and complex, containing more than 85% repetitive DNA. To provide a foundation for improvement through molecular breeding, in 2005, the International Wheat Genome Sequencing Consortium set out to deliver a high-quality annotated reference genome sequence of bread wheat. Results: An annotated reference sequence representing the hexaploid bread wheat genome in the form of 21 chromosome-like sequence assemblies has now been delivered, giving access to 107,891 high-confidence genes, including their genomic context of regulatory sequences. This assembly enabled the discovery of tissue- and developmental stage–related gene coexpression networks using a transcriptome atlas representing all stages of wheat development. The dynamics of change in complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. Aspects of the future value of the annotated assembly for molecular breeding and research were exemplarily illustrated by resolving the genetic basis of a quantitative trait locus conferring resistance to abiotic stress and insect damage as well as by serving as the basis for genome editing of the flowering-time trait. Conclusion: This annotated reference sequence of wheat is a resource that can now drive disruptive innovation in wheat improvement, as this community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding. Importantly, the bioinformatics capacity developed for model-organism genomes will facilitate a better understanding of the wheat genome as a result of the high-quality chromosome-based genome assembly. By necessity, breeders work with the genome at the whole chromosome level, as each new cross involves the modification of genome-wide gene networks that control the expression of complex traits such as yield. With the annotated and ordered reference genome sequence in place, researchers and breeders can now easily access sequence-level information to precisely define the necessary changes in the genomes for breeding programs. This will be realized through the implementation of new DNA marker platforms and targeted breeding technologies, including genome editing