Vulnerable bodies, vulnerable systems

In this paper we examine the concept of vulnerability as it relates to the materiality of systems, the exclusion of human physical corporeality, and social exclusion in Luhmann’s theory of social autopoiesis. We ask whether a concept of vulnerability can be included in autopoiesis in order to better conceptualise social exclusion and the excluded, with a view to understanding how, if at all, the dangers posed by this exclusion are mitigated by autopoietic processes. We are emphatically not returning to the human subject over operational systems, but seek instead to develop an understanding of the embodied nature of humans and their vulnerability within an autopoietic framework. We argue that the awareness of the risks to social functional differentiation posed by unmanaged exclusion – disenchantment, disassociation, and, most drastically, dedifferentiation – provided by our analysis indicates why hyper-exclusion must be mitigated

TriG - A GNSS Precise Orbit and Radio Occultation Space Receiver

The GPS radio occultation (RO) technique [1] produces measurements in the ionosphere and neutral atmosphere [2] that contribute to monitoring space weather and climate change; and improving operational weather prediction. The high accuracy of RO soundings, traceable to SI standards, makes them ideal climate benchmark observations. For weather applications, RO observations improve the accuracy of weather forecasts by providing temperature and moisture profiles of sub-km vertical resolution, over land and ocean and in the presence of clouds. JPL is currently flying a handful of RO instruments [3] on various satellites in Low Earth Orbit (LEO). Although these receivers have served to pioneer occultation measurements, various advances in technology and understanding of the RO technique along with availability of new signals from GPS and other GNSS satellites allow us to design an improved next generation space-based Precise Orbit Determination (POD) and RO receiver, the TriG receiver. The paper describes the architecture and implementation of the JPL TriG receiver as well as results obtained with a prototype receiver demonstrating key technologies necessary for a next-generation space science receiver

The Relationship Between Interleukin-6 in Saliva, Venous and Capillary Plasma, at Rest and in Response to Exercise

IL-6 plays a mechanistic role in conditions such as metabolic syndrome, chronic fatigue syndrome and clinical depression and also plays a major role in inflammatory and immune responses to exercise. The purpose of this study was to investigate the levels of resting and post exercise IL-6 when measured in venous plasma, saliva and capillary plasma. Five male and five females completed 2 separate exercise trials, both of which involved standardized exercise sessions on a cycle ergometer. Venous blood and saliva samples were taken immediately before and after Trial A, venous and capillary blood samples were taken immediately before and after Trial B. IL-6 values were obtained using a high-sensitivity enzyme-linked immunosorbent assay (ELISA). In Trial A venous plasma IL-6 increased significantly from 0.4. 0.14. pg/ml to 0.99 0.29. pg/ml (. P<. 0.01) while there was no increase in salivary IL-6. Venous plasma and salivary IL-6 responses were not correlated at rest, post exercise or when expressed as an exercise induced change. In Trial B venous and capillary plasma IL-6 increased significantly (venous: 0.22. ±. 0.18 to 0.74. ±. 0.28. pg/ml; capillary: 0.37. ±. 0.22 to 1.08. ±. 0.30. pg/ml (. P<. 0.01). Venous and capillary plasma responses did not correlate at rest (. r=. 0.59, P=. 0.07) but did correlate post exercise (. r=. 0.79) and when expressed as an exercise induced change (. r=. 0.71, P=. 0.02). Saliva does not appear to reflect systemic IL-6 responses, either at rest or in response to exercise. Conversely, capillary plasma responses are reflective of systemic IL-6 responses to exercise. © 2014 Elsevier Ltd

Жидкофазные коллоиды серебра и меди, получаемые электронно-лучевым испарением металлов в вакууме

ЭЛЕКТРОННО-ЛУЧЕВАЯ ТЕХНОЛОГИЯКОЛЛОИДЫНАНОЧАСТИЦЫ МЕДИНАНОЧАСТИЦЫ СЕРЕБРАДИСПЕРСНО-УПРОЧНЕННЫЕ МАТЕРИАЛЫНАНОТЕХНОЛОГИ

Soil natural capital quantification by the stock adequacy method

AbstractA method is presented for assessing soil natural capital based on the principles of land evaluation. Policymakers are adopting concepts of flows of ecosystem services, and the natural capital stocks that support them, to provide more integrated analyses of the trade-offs between environmental, economic, social and cultural outcomes from land use. Soil is frequently overlooked in these analyses. Techniques are needed to quantify and map soil natural capital and their potential to provide ecosystem services to enable the soil science community to more effectively engage with decision-makers. To support this engagement, these techniques need to use available soil survey maps and databases to provide extensive geographic coverage of soil natural capital estimates. The method presented estimates the adequacy of soil natural capital stocks to support the soil processes behind the provision of ecosystem services under a specific land use. A stock adequacy index estimates the degree to which the provision of services is limited by soil natural capital stocks or advantaged by a stock surplus under a given land use. Reference values are derived from a curve of the response of the provision of the service to key soil stocks for a specified land use. These curves are determined from land evaluation and soil quality literature, or by modelling. The method is essentially an extension of land evaluation in which the evaluations are calibrated using an ecosystem approach. The output indices provide information about potential ecosystem services provision, land-use suitability, soil resource use efficiency, and environmental performance. Outputs from the method are demonstrated for a range of soils under pastoral dairy land use in Wairarapa, New Zealand

The epidemiology of UK autoimmune liver disease varies with geographic latitude

BACKGROUND & AIMS: The epidemiology of autoimmune liver disease (AILD) is challenging to study because of the diseases’ rarity and because of cohort selection bias. Increased incidence farther from the Equator has been reported for multiple sclerosis, another autoimmune disease. We assessed the incidence of primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH) in relation to latitude. METHODS: We performed a retrospective cohort study using anonymized UK primary care records from January 1, 2002, to May 10, 2016. All adults without a baseline diagnosis of AILD were included and followed up until the first occurrence of an AILD diagnosis, death, or they left the database. Latitude was measured as registered general practice rounded down to whole degrees. RESULTS: The cohort included 8,590,421 records with 53.3 × 10(7) years of follow-up evaluation from 694 practices. There were 1314 incident cases of PBC, 396 of PSC, and 1034 of AIH. Crude incidences were as follows: PBC, 2.47 (95% CI, 2.34–2.60); PSC, 0.74 (95% CI, 0.67–0.82); and AIH, 1.94 (95% CI, 1.83–2.06) per 100,000 per year. PBC incidence correlated with female sex, smoking, and deprivation; PSC incidence correlated with male sex and non-smoking; AIH incidence correlated with female sex and deprivation. A more northerly latitude was associated strongly with incidence of PBC: 2.16 (95% CI, 1.79–2.60) to 4.86 (95% CI, 3.93–6.00) from 50°N to 57°N (P = .002) and incidence of AIH: 2.00 (95% CI, 1.65–2.43) to 3.28 (95% CI, 2.53–4.24) (P = .003), but not incidence of PSC: 0.82 (95% CI, 0.60–1.11) to 1.02 (95% CI, 0.64–1.61) (P = .473). Incidence after adjustment for age, sex, smoking, and deprivation status showed similar positive correlations for PBC and AIH with latitude, but not PSC. Incident AIH cases were younger at more northerly latitude. CONCLUSIONS: We describe an association in the United Kingdom between more northerly latitude and the incidence of PBC and AIH that requires both confirmation and explanation