1,439 research outputs found
Trace ideals for Fourier integral operators with non-smooth symbols II
We consider Fourier integral operators with symbols in modulation spaces and
non-smooth phase functions whose second orders of derivatives belong to certain
types of modulation space. We establish continuity and Schatten-von Neumann
properties of such operators when acting on modulation spaces.Comment: 25 page
Changes of variables in modulation and Wiener amalgam spaces
In this paper various properties of global and local changes of variables as well as properties of canonical transforms are investigated on modulation and Wiener amalgam spaces. We establish several relations among localisations of such spaces and, as a consequence, we obtain several versions of local and global Beurling–Helson type theorems. We also establish a number of positive results such as local boundedness of canonical transforms on modulation spaces, properties of homogeneous changes of variables, and local continuity of Fourier integral operators on equation image. Finally, counterparts of these results are discussed for spaces on the torus
Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability.
Oncogenes and oncosuppressors can deregulate cell replication in tumours, and recently have been shown to influence the probability of apoptosis. The effects of human c-myc and mutated (T24) Ha-ras oncogenes on susceptibility to apoptosis were investigated by introducing them into immortalised rat fibroblasts. The resulting family of transfectants showed closely similar measures of proliferation, but widely divergent rates of apoptosis, differing by up to fifteen-fold, that correlated inversely with population expansion rates in vitro. T24-ras transfectants with moderate or high p21ras expression showed reduced apoptosis, and this was reversed by pharmacological inhibition of membrane localisation of p21ras by mevinolin. In contrast, c-myc stimulated apoptosis, and this was further enhanced by serum deprivation. Inducibility of effector proteins represents one possible mechanism of genetic control of the susceptibility to apoptosis, and its investigation showed that c-myc was associated with expression by viable cells of latent calcium/magnesium sensitive endonuclease activity characteristic of apoptosis. In contrast, endonuclease activity was not detected in viable cells of a T24-ras transfectant expressing high levels of p21ras. Thus, there appeared to be differential regulation of susceptibility to apoptosis, positively by c-myc and negatively by activated ras, and this was associated with availability of endonuclease activity. Genetic modulation of apoptosis in human neoplasms is likely to influence net growth rate, retention of cells acquiring new mutations and response to certain chemotherapeutic agents
Evaluation of the potential use of risk-based sampling to surveillance of antibacterial residues in Danish pork
Consumers consider presence of chemical substances in food products as undesirable. In Denmark, more than 20,000 samples are analysed each year for presence of antibacterial residues in Danish slaughter pigs, and these surveillance data indicate that the true antibacterial residue prevalence in Danish slaughter pigs is negligible. The question has been raised whether it would be possible to improve the cost-effectiveness of the surveillance programme. This was addressed in this study
Phonon-induced quadrupolar ordering of the magnetic superconductor TmNiBC
We present synchrotron x-ray diffraction studies revealing that the lattice
of thulium borocarbide is distorted below T_Q = 13.5 K at zero field. T_Q
increases and the amplitude of the displacements is drastically enhanced, by a
factor of 10 at 60 kOe, when a magnetic field is applied along [100]. The
distortion occurs at the same wave vector as the antiferromagnetic ordering
induced by the a-axis field. A model is presented that accounts for the
properties of the quadrupolar phase and explains the peculiar behavior of the
antiferromagnetic ordering previously observed in this compound.Comment: submitted to PR
Adiabaticity Conditions for Volatility Smile in Black-Scholes Pricing Model
Our derivation of the distribution function for future returns is based on
the risk neutral approach which gives a functional dependence for the European
call (put) option price, C(K), given the strike price, K, and the distribution
function of the returns. We derive this distribution function using for C(K) a
Black-Scholes (BS) expression with volatility in the form of a volatility
smile. We show that this approach based on a volatility smile leads to relative
minima for the distribution function ("bad" probabilities) never observed in
real data and, in the worst cases, negative probabilities. We show that these
undesirable effects can be eliminated by requiring "adiabatic" conditions on
the volatility smile
Review: Attachment and attachment-related outcomes in preschool children – a review of recent evidence
Background
Secure attachment is associated with optimal outcomes across all domains in childhood, and both insecure and disorganised attachment are associated with a range of later psychopathologies. Insecure and disorganised attachment are common, particularly in disadvantaged populations, pointing to the need to identify effective methods of addressing such problems.
Aims
This paper presents the findings of a review of secondary and primary studies evaluating the effectiveness of interventions aimed at improving attachment and attachment-related outcomes on a universal, targeted or indicated basis, which was undertaken as part of an update of the evidence base for a UK-based national programme targeting children aged 0–5 years (Healthy Child Programme).
Method
A systematic search of key electronic databases was undertaken to identify secondary and primary sources of data that addressed the research question and that had been published between 2008 and 2014; search sources included Cochrane Collaboration, NICE, EPPI Centre, Campbell Collaboration and PubMed, PsychInfo, CINAHL databases.
Findings
Six systematic reviews and 11 randomised controlled trials were identified that had evaluated the effectiveness of universal, selective or indicated interventions aimed at improving attachment and attachment-related outcomes in children aged 0–5 years. Potentially effective methods of improving infant attachment include parent–infant psychotherapy, video feedback and mentalisation-based programmes. Methods that appear to be effective in improving attachment-related outcomes include home visiting and parenting programmes.
Conclusions
A number of methods of working to promote attachment and attachment-related outcomes in preschool children are now being recommended as part of the Healthy Child Programme. The implications in terms of the role and contribution of practitioners working in child and adolescent mental health service are discusse
A Turnover in the Galaxy Main Sequence of Star Formation at for Redshifts
The relationship between galaxy star formation rates (SFR) and stellar masses
() is re-examined using a mass-selected sample of 62,000
star-forming galaxies at in the COSMOS 2-deg field. Using new
far-infrared photometry from -PACS and SPIRE and -MIPS 24
m, along with derived infrared luminosities from the NRK method based on
galaxies' locations in the restframe color-color diagram vs. , we are able to more accurately determine total SFRs for our complete
sample. At all redshifts, the relationship between median and
follows a power-law at low stellar masses, and flattens to nearly constant SFR
at high stellar masses. We describe a new parameterization that provides the
best fit to the main sequence and characterizes the low mass power-law slope,
turnover mass, and overall scaling. The turnover in the main sequence occurs at
a characteristic mass of about at all redshifts.
The low mass power-law slope ranges from 0.9-1.3 and the overall scaling rises
in SFR as a function of . A broken power-law fit below
and above the turnover mass gives relationships of below the turnover mass and above
the turnover mass. Galaxies more massive than have on average, a much lower specific star formation rate (sSFR) than
would be expected by simply extrapolating the traditional linear fit to the
main sequence found for less massive galaxies.Comment: 16 pages, 7 figures. Accepted for publication in Ap
The Space Density and Colors of Massive Galaxies at 2<z<3: the Predominance of Distant Red Galaxies
Using the deep multi-wavelength MUSYC, GOODS, and FIRES surveys we construct
a stellar mass-limited sample of galaxies at 2<z<3. The sample comprises 294
galaxies with M>10^11 Solar masses distributed over four independent fields
with a total area of almost 400 sq arcmin. The mean number density of massive
galaxies in this redshift range is (2.2+-0.6) x 10^-4 Mpc^-3. We present median
values and 25th and 75th percentiles for the distributions of observed R mags,
observed J-K colors, and rest-frame UV continuum slopes, M/L(V) ratios, and U-V
colors. The galaxies show a large range in all these properties. The ``median
galaxy'' is faint in the observer's optical (R=25.9), red in the observed
near-IR (J-K=2.48), has a rest-frame UV spectrum which is relatively flat
(beta=-0.4), and rest-frame optical colors resembling those of nearby spiral
galaxies (U-V=0.62). We determine which galaxies would be selected as Lyman
break galaxies (LBGs) or Distant Red Galaxies (DRGs, having J-K>2.3) in this
mass-limited sample. By number DRGs make up 69% of the sample and LBGs 20%,
with a small amount of overlap. By mass DRGs make up 77% and LBGs 17%. Neither
technique provides a representative sample of massive galaxies at 2<z<3 as they
only sample the extremes of the population. As we show here, multi-wavelength
surveys with high quality photometry are essential for an unbiased census of
massive galaxies in the early Universe. The main uncertainty in this analysis
is our reliance on photometric redshifts; confirmation of the results presented
here requires extensive near-infrared spectroscopy of optically-faint samples.Comment: Accepted for publication in ApJ Letter
High resolution observations and mass modelling of the CLASS gravitational lens B1152+199
We present a series of high resolution radio and optical observations of the
CLASS gravitational lens system B1152+199 obtained with the Multi-Element
Radio-Linked Interferometer Network (MERLIN), Very Long Baseline Array (VLBA)
and Hubble Space Telescope (HST). Based on the milliarcsecond-scale
substructure of the lensed radio components and precise optical astrometry for
the lensing galaxy, we construct models for the system and place constraints on
the galaxy mass profile. For a single galaxy model with surface mass density
Sigma(r) propto r^-beta, we find that 0.95 < beta < 1.21 at 2-sigma confidence.
Including a second deflector to represent a possible satellite galaxy of the
primary lens leads to slightly steeper mass profiles.Comment: 7 pages, post-referee revision for MNRA
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