An examination of human anatomy in the drama of the early modern period

An examination of the science of human anatomy and dissection as it occurs in plays of the early modern period. Starting with a survey of available literature on the subject, the thesis then moves on to examine the state of human anatomy in England at the time as well as an overview medical training, textbooks and information that may have been available to the public at large. This leads to an examination of a group of plays that refer explicitly to the practice of anatomy, references that are found to be either literal or metaphorical in nature. In this, the theatrical representation of anatomy is examined with an eye toward investigating the nature of these representations

FAP206 is a Microtubule-Docking Adapter for Ciliary Radial Spoke 2 and Dynein c

Radial spokes are conserved macromolecular complexes that are essential for ciliary motility. A triplet of three radial spokes, RS1, RS2, and RS3, repeats every 96 nm along the doublet microtubules. Each spoke has a distinct base that docks to the doublet and is linked to different inner dynein arms. Little is known about the assembly and functions of individual radial spokes. A knockout of the conserved ciliary protein FAP206 in the ciliate Tetrahymena resulted in slow cell motility. Cryo–electron tomography showed that in the absence of FAP206, the 96-nm repeats lacked RS2 and dynein c. Occasionally, RS2 assembled but lacked both the front prong of its microtubule base and dynein c, whose tail is attached to the front prong. Overexpressed GFP-FAP206 decorated nonciliary microtubules in vivo. Thus FAP206 is likely part of the front prong and docks RS2 and dynein c to the microtubule

Advancing Creativity Theory and Research: A Socio-cultural Manifesto

This manifesto, discussed by 20 scholars, representing diverse lines of creativity research, marks a conceptual shift within the field. Socio-cultural approaches have made substantial contributions to the concept of creativity over recent decades and today can provide a set of propositions to guide our understanding of past research and to generate new directions of inquiry and practice. These propositions are urgently needed in response to the transition from the Information Society to the Post-Information Society. Through the propositions outlined here, we aim to build common ground and invite the community of creativity researchers and practitioners to reflect up, study, and cultivate creativity as a socio-cultural phenomenon

The genesis of gold mineralisation hosted by orogenic belts: A lead isotope investigation of Irish gold deposits

Lead isotope analyses have been performed on 109 gold and 23 sulphide samples from 34 Irish gold occurrences, including 27 placers, and used to shed light on the sources of mineralising fluids and metals associated with gold mineralisation hosted by orogenic belts. The Pb isotope ratios of lode and placer gold range from 206Pb/204Pb=17.287-18.679, 207Pb/204Pb=15.382-15.661, and 208Pb/204Pb=37.517-38.635, consistent with the Pb isotopic data on previously reported Irish sulphide mineralisation. There is no evidence that gold mineralisation is associated with distinctive source regions, and it appears to have been derived from similar sources to those responsible for the widespread sulphide mineralisation in Ireland. It is inferred that the principal controls on the Au mineralisation are structural and not related to the distribution of Au in their source rocks. The range of Pb isotope ratios favours the interaction of multiple source reservoirs predominantly during the Caledonian Orogeny (c. 475-380Ma). Underlying basement was the primary control on two key sources of Pb. Gold occurrences located to the south-east of the Iapetus Suture are characterised by Pb compositions that derive predominantly from the Late Proterozoic crustal basement or overlying Lower Palaeozoic sediments, whilst those located north-west of the Iapetus Suture are characterised by less radiogenic Pb signatures derived predominantly from Late Proterozoic or older crustal basement. A third source, relatively enriched in radiogenic Pb, also played a role in the formation of a number of Irish gold occurrences, and may have been associated with syn- to post-orogenic intrusives. Magmatic processes may therefore have played an important role in the formation of some orogenic gold occurrences

John Ford's "Tis pity she's a whore"

Bibliography: p. 111-11

Through the Mill: A Living Newspaper

The “Living Newspaper” is a form of agitprop theatre that arose in Bolshevik Russia, that urged social change through non-realistic and non-natural theatrical techniques. This live performance was created through direct interviews with community members and collective creation techniques, and examines issues surrounding the potential closure of the pulp and paper mill in Corner Brook. It includes multimedia, music, song, and dramatic dialogue, and is a collaboration between theatre faculty members, the community theatre, and students

Electrophysiology of Tetrahymena

The focus in an electrophysiological analysis is the physical health of the cell. This is represented by a reliable, steady, and deep (hyperpolarized) resting membrane potential. A high membrane resistance is also necessary for an electrophysiological analysis. For any condition, many cell membrane potentials should be measured (at least three to ten cells) to establish the baseline, control level. Normal ciliary beating should also be observed. When a cell is damaged, it is often easy to see irregular or slowed ciliary beating, indicating either an uncoordinated or depolarized state. If a resting membrane potential has been established, an irreversible depolarizing drift may also indicate cell damage. A decreased membrane resistance is also an indication of cell damage. A good test of cell condition is to induce an action potential by current injection through the membrane potential recording electrode. This is easily done by using a 1-nA electrode resistance calibration pulse that is commonly a feature of modern recording devices. If the cell shows a visible jerk backward, it ensures that the electrode is inside the cell and that the cell is healthy enough to show a strong response