Probing Spin-Polarized Currents in the Quantum Hall Regime

An experiment to probe spin-polarized currents in the quantum Hall regime is suggested that takes advantage of the large Zeeman-splitting in the paramagnetic diluted magnetic semiconductor zinc manganese selenide (Zn$_{1-x}$Mn$_x$Se). In the proposed experiment spin-polarized electrons are injected by ZnMnSe-contacts into a gallium arsenide (GaAs) two-dimensional electron gas (2DEG) arranged in a Hall bar geometry. We calculated the resulting Hall resistance for this experimental setup within the framework of the Landauer-B\"uttiker formalism. These calculations predict for 100% spininjection through the ZnMnSe-contacts a Hall resistance twice as high as in the case of no spin-polarized injection of charge carriers into a 2DEG for filling factor $\nu=2$. We also investigated the influence of the equilibration of the spin-polarized electrons within the 2DEG on the Hall resistance. In addition, in our model we expect no coupling between the contact and the 2DEG for odd filling factors of the 2DEG for 100% spininjection, because of the opposite sign of the g-factors of ZnMnSe and GaAs.Comment: 7 pages, 5 figure

Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.

Healthy aging depends on removal of damaged cellular material that is in part mediated by autophagy. The nutritional status of cells affects both aging and autophagy through as-yet-elusive metabolic circuitries. Here, we show that nucleocytosolic acetyl-coenzyme A (AcCoA) production is a metabolic repressor of autophagy during aging in yeast. Blocking the mitochondrial route to AcCoA by deletion of the CoA-transferase ACH1 caused cytosolic accumulation of the AcCoA precursor acetate. This led to hyperactivation of nucleocytosolic AcCoA-synthetase Acs2p, triggering histone acetylation, repression of autophagy genes, and an age-dependent defect in autophagic flux, culminating in a reduced lifespan. Inhibition of nutrient signaling failed to restore, while simultaneous knockdown of ACS2 reinstated, autophagy and survival of ach1 mutant. Brain-specific knockdown of Drosophila AcCoA synthetase was sufficient to enhance autophagic protein clearance and prolong lifespan. Since AcCoA integrates various nutrition pathways, our findings may explain diet-dependent lifespan and autophagy regulation

Активность микрофлоры как показатель токсичности морских донных отложений шельфовой зоны Черного моря и Керченского пролива

Изучена потенциальная активность донной микрофлоры в местах утечки остатков химических токсикантов, затопленных в период Второй Мировой войны ХХ в. Отмечены особенности восстановления жизнедеятельности микрофлоры при различных уровнях загрязнения донных отложений мышьяком и хлорированными органическими сульфидами. Полученные результаты перспективно использовать при оценке экологического состояния донных отложений в загрязненных прибрежных акваториях

First Results of the 140^{140}Ce(n,γ)141^{141}Ce Cross-Section Measurement at n_TOF

An accurate measurement of the $^{140}$Ce(n,γ) energy-dependent cross-section was performed at the n_TOF facility at CERN. This cross-section is of great importance because it represents a bottleneck for the s-process nucleosynthesis and determines to a large extent the cerium abundance in stars. The measurement was motivated by the significant difference between the cerium abundance measured in globular clusters and the value predicted by theoretical stellar models. This discrepancy can be ascribed to an overestimation of the $^{140}$Ce capture cross-section due to a lack of accurate nuclear data. For this measurement, we used a sample of cerium oxide enriched in $^{140}$Ce to 99.4%. The experimental apparatus consisted of four deuterated benzene liquid scintillator detectors, which allowed us to overcome the difficulties present in the previous measurements, thanks to their very low neutron sensitivity. The accurate analysis of the p-wave resonances and the calculation of their average parameters are fundamental to improve the evaluation of the $^{140}$Ce Maxwellian-averaged cross-section

First Results of the 140^{140}Ce(n,γ)141^{141}Ce Cross-Section Measurement at n_TOF

An accurate measurement of the $^{140}$Ce(n,γ) energy-dependent cross-section was performed at the n_TOF facility at CERN. This cross-section is of great importance because it represents a bottleneck for the s-process nucleosynthesis and determines to a large extent the cerium abundance in stars. The measurement was motivated by the significant difference between the cerium abundance measured in globular clusters and the value predicted by theoretical stellar models. This discrepancy can be ascribed to an overestimation of the $^{140}$Ce capture cross-section due to a lack of accurate nuclear data. For this measurement, we used a sample of cerium oxide enriched in $^{140}$Ce to 99.4%. The experimental apparatus consisted of four deuterated benzene liquid scintillator detectors, which allowed us to overcome the difficulties present in the previous measurements, thanks to their very low neutron sensitivity. The accurate analysis of the p-wave resonances and the calculation of their average parameters are fundamental to improve the evaluation of the $^{140}$Ce Maxwellian-averaged cross-section

The neutron and its role in cosmology and particle physics

Experiments with cold and ultracold neutrons have reached a level of precision such that problems far beyond the scale of the present Standard Model of particle physics become accessible to experimental investigation. Due to the close links between particle physics and cosmology, these studies also permit a deep look into the very first instances of our universe. First addressed in this article, both in theory and experiment, is the problem of baryogenesis ... The question how baryogenesis could have happened is open to experimental tests, and it turns out that this problem can be curbed by the very stringent limits on an electric dipole moment of the neutron, a quantity that also has deep implications for particle physics. Then we discuss the recent spectacular observation of neutron quantization in the earth's gravitational field and of resonance transitions between such gravitational energy states. These measurements, together with new evaluations of neutron scattering data, set new constraints on deviations from Newton's gravitational law at the picometer scale. Such deviations are predicted in modern theories with extra-dimensions that propose unification of the Planck scale with the scale of the Standard Model ... Another main topic is the weak-interaction parameters in various fields of physics and astrophysics that must all be derived from measured neutron decay data. Up to now, about 10 different neutron decay observables have been measured, much more than needed in the electroweak Standard Model. This allows various precise tests for new physics beyond the Standard Model, competing with or surpassing similar tests at high-energy. The review ends with a discussion of neutron and nuclear data required in the synthesis of the elements during the "first three minutes" and later on in stellar nucleosynthesis.Comment: 91 pages, 30 figures, accepted by Reviews of Modern Physic

Canine Brachycephaly is Associated with a Retrotransposon-Mediated Missplicing of SMOC2

In morphological terms, “form” is used to describe an object’s shape and size. In dogs, facial form is stunningly diverse. Facial retrusion, the proximodistal shortening of the snout and widening of the hard palate is common to brachycephalic dogs and is a welfare concern, as the incidence of respiratory distress and ocular trauma observed in this class of dogs is highly correlated with their skull form. Progress to identify the molecular underpinnings of facial retrusion is limited to association of a missense mutation in BMP3 among small brachycephalic dogs. Here, we used morphometrics of skull isosurfaces derived from 374 pedigree and mixed-breed dogs to dissect the genetics of skull form. Through deconvolution of facial forms, we identified quantitative trait loci that are responsible for canine facial shapes and sizes. Our novel insights include recognition that the FGF4 retrogene insertion, previously associated with appendicular chondrodysplasia, also reduces neurocranium size. Focusing on facial shape, we resolved a quantitative trait locus on canine chromosome 1 to a 188-kb critical interval that encompasses SMOC2. An intronic, transposable element within SMOC2 promotes the utilization of cryptic splice sites, causing its incorporation into transcripts, and drastically reduces SMOC2 gene expression in brachycephalic dogs. SMOC2 disruption affects the facial skeleton in a dose-dependent manner. The size effects of the associated SMOC2 haplotype are profound, accounting for 36% of facial length variation in the dogs we tested. Our data bring new focus to SMOC2 by highlighting its clinical implications in both human and veterinary medicine

MBE-Wachstum von ZnMnSe zur Spininjektion in GaAs/AlGaAs-Heterostrukturen

Gegenstand dieser Arbeit ist die Entwicklung und die Herstellung von Halbleiterheterostrukturen, um mit elektrischen Transportexperimenten den Nachweis der elektrischen Injektion spinpolarisierter Elektronen in ein zweidimensionales Elektronengas (2DEG) zu erbringen. Hochbewegliche GaAs/AlGaAs-2DEG-Heterostrukturen wurden mit Kontakten aus dem verdünnten magnetischen Halbleiter ZnMnSe versehen, der sich bei tiefen Temperaturen und kleinem externen Magnetfeld durch eine nahezu vollständige Polarisation der Elektronenspins auszeichnet. Ein in dieser Arbeit vorgestelltes Konzept erbringt den Nachweis der Spininjektion auf der Grundlage der den niederdimensionalen Systemen eigenen Quanteneffekte. Die theoretischen Betrachtungen im ganzzahligen Quanten-Hall-Regime vollständiger Randkanalleitung beziehen die durch die Zeeman-Aufspaltung des Leitungsbandes hervorgerufene Spinpolarisation der Kontakte und die durch Spin-Bahn-Effekte verursachte Equilibrierung zwischen spinaufgespaltenen Randkanälen mit ein. Mittels Molekularstrahlepitaxie gelang die Zucht strukturell hochwertiger, n-leitender ZnMnSe-Schichten auf unterschiedlichen GaAs-Oberflächen. Die strukturelle Qualität und der stöchiometrische Mn-Gehalt ließen sich durch Röntgendiffraktometrie ermitteln. Magnetfeldabhängige Photolumineszenzmessungen verifizierten die für die Spininjektion so bedeutende riesige Zeeman-Aufspaltung im Leitungsband der ZnMnSe-Proben und dienten zur Bestimmung des effektiven g-Faktors sowie des effektiven und strukturellen Mn-Gehalts. Der Magnetowiderstand bei tiefen Temperaturen zeigte dabei den auch für andere verdünnte magnetische Halbleiter typischen Verlauf. Die GaAs/AlGaAs-2DEG-Heterostruktur wurde unterstützt durch Bandstruktursimulationen hinsichtlich der Reduktion interner Potentialbarrieren weiter entwickelt, optimierte Wachstumsbedingungen resultierten in einem deutlichen Anstieg der Elektronenbeweglichkeit. Besondere Aufmerksamkeit erfuhr die Grenzflächenpräparation am heteropolaren ZnMnSe-Ga(Al)As-Übergang, die einen maßgeblichen Einfluss auf die energetische Leitungsbandanpassung zwischen dem II-VI und dem III-V-Halbleiter ausübt. Erstmals konnte im Rahmen dieser Arbeit an einer mit semimagnetischen ZnMnSe-Kontakten versehenen GaAs/AlGaAs-Heterostruktur Quantentransport gemessen werden