The Hunt for Science Diplomacy: Practice and Perceptions in the Horizon 2020 Scientific Community. EL-CSID Working Paper Issue 2018/18 • June 2018

There are many illustrations from recent history of what we now call science diplomacy; for example, where nations have advanced scientific collaboration to build relationships and smooth hostilities in the period post World War II. However, compared to other fields such as cultural diplomacy, academics and policy makers have only recently begun to investigate and develop frameworks and tools for ‘science diplomacy’. We are still in the process of testing the limits of the concept, which can most readily be explained as actions that exist at the interface of scientific practice and foreign policy. Science is often considered alongside culture as a tool of soft power (Nye, 1990) but there are several critical differences between the two fields and they should not be given a false equivalence as a diplomatic tool. Cultural practice and knowledge are by their very nature fundamentally linked to a particular nation or group; it can be shared without diminution in value and is very difficult to lose. Science knowledge and practices on the other hand, can be transferred, sold or stolen, and used for the economic benefit or advancement of others. Intellectual property has independent economic value and must be protected; its loss can diminish competitiveness, influence and lead to conflict between states (as we see in contemporary US, China relations). Its application leads to tradeable technology and goods and hard economic advantage. Taking liberties with Nye’s (1990) classic terminology, if cultural diplomacy is the runny egg of soft power, then scientific diplomacy is much harder boiled

Girl Power? An analysis of peer effects using exogenous changes in the gender make-up of the peer group.

The effect of a child’s peers has long been regarded as an important factor in affecting their educational outcomes. However, these effects are often difficult to estimate. I use exogenous changes in the proportion of girls within English school cohorts to estimate the effect of a more female peer group, estimated in all schools, and in a subset of schools that only include one classroom per academic year. I find significant negative effects of a more female peer group on boys’ outcomes in English. In maths and science, all pupils benefit from a more female peer group up until age 11.peer groups, education

Peer effects in English Primary schools: An IV estimation on the effect of a more able peer group on age 11 examination results

The magnitude and characteristics of the effect of a child’s peers on their outcomes has long interested researchers and policy makers. In this paper, I take advantage of the correlation between the average outcomes a child’s peer group attains with the distribution of ages within the cohort to construct an instrument for the ability of the peer group in order to estimate the peers effects on children’s outcomes at age 11. IV results suggest there is a significant positive effect of a more able peer group. Furthermore, the results suggest that there is more benefit for children who are close to the ability of the peer group than those whose ability is not close.peer groups, primary education

Student effort and educational attainment: Using the England football team to identify the education production function.

We use a sharp, exogenous and repeated change in the value of leisure to identify the impact of student effort on educational achievement. The treatment arises from the partial overlap of the world’s major international football tournaments with the exam period in England. Our data enable a clean difference-in-difference design. Performance is measured using the high-stakes tests that all students take at the end of compulsory schooling. We find a strongly significant effect: the average impact of a fall in effort is 0.12 SDs of student performance, significantly larger for male and disadvantaged students, as high as many educational policies.student effort, educational achievement, schools

Diagnostic techniques in deflagration and detonation studies

Advances in experimental, high-speed techniques can be used to explore the processes occurring within energetic materials. This review describes techniques used to study a wide range of processes: hot-spot formation, ignition thresholds, deflagration, sensitivity and finally the detonation process. As this is a wide field the focus will be on small-scale experiments and quantitative studies. It is important that such studies are linked to predictive models, which inform the experimental design process. The stimuli range includes, thermal ignition, drop-weight, Hopkinson Bar and Plate Impact studies. Studies made with inert simulants are also included as these are important in differentiating between reactive response and purely mechanical behaviour

Evaluation of capacitors for space propulsion applications final progress report

Low inductance energy storage capacitors for space propulsion application

From the individual to the community and beyond: water quality, stress indicators and key species in coastal waters

This review examines water quality and stress indicators at levels of organisation from the individual to the community and beyond by means of three case studies concentrating on rocky shores within the north-east Atlantic. Responses of dogwhelks (Nucella) to tributyltin pollution from antifouling paints is examined as the main case study. There are effects at the individual level (development of male sexual characteristics in the female leading to effective sterility) and population level (reduction in juveniles, few females and eventual population disappearance of dogwhelks in badly contaminated areas) but information on community level effects of dogwhelk demise is sparse. Such effects were simulated by dogwhelk removal experiments on well studied, moderately exposed ledges on shores on the Isle of Man. The removal of dogwhelks reduced the size and longevity of newly established Fucus clumps that had escaped grazing. Removal of dogwhelks also increased the likelihood of algal escapes. In a factorial experiment dogwhelks were shown to be less important than limpets \{Patella) in structuring communities but still had a significant modifying effect by increasing the probability of algal escapes. Community level responses to stress on rocky shores are then explored by reference to catastrophic impacts such as oil spills, using the Torrey Canyon as a case study. Recovery of the system in response to this major perturbation took between 10-15 years through a series of damped oscillations. The final case study is that of indicators of ecosystem level change in response to climate fluctuations, using ratios of northern \{Semibalanus balanoides) and southern (Chthamalus spp.) barnacles. Indices derived from counts on the shore show good correlations with inshore sea-water temperatures after a 2-year lag phase. The use of barnacles to measure offshore changes is reviewed. The discussion considers the use of bioindicators at various levels of organisation

The PSF.p54nrb complex is a novel Mnk substrate that binds the mRNA for tumor necrosis factor alpha

To identify new potential substrates for the MAP kinase signal-integrating kinases (Mnks), we employed a proteomic approach. The Mnks are targeted to the translational machinery through their interaction with the cap-binding initiation factor complex. We tested whether proteins retained on cap resin were substrates for the Mnks in vitro, and identified one such protein as PSF (the PTB (polypyrimidine tract-binding protein)-associated splicing factor). Mnks phosphorylate PSF at two sites in vitro, and our data show that PSF is an Mnk substrate in vivo. We also demonstrate that PSF, together with its partner, p54nrb, binds RNAs that contain AU-rich elements (AREs), such as those for proinflammatory cytokines (e.g. tumor necrosis factor ? (TNF?)). Indeed, PSF associates specifically with the TNF? mRNA in living cells. PSF is phosphorylated at two sites by the Mnks. Our data show that Mnk-mediated phosphorylation increases the binding of PSF to the TNF? mRNA in living cells. These findings identify a novel Mnk substrate. They also suggest that the Mnk-catalyzed phosphorylation of PSF may regulate the fate of specific mRNAs by modulating their binding to PSF·p54nrb