Pollution from mines in the 'New Lead Belt' of South Eastern Missouri

Students supported: 2 Research AssistantsIn the south eastern part of Missouri, the Clark National Forest straddles the Ozark Plateau and contains the headwaters of some of the most beautiful rivers in the state. This scenic part of Missouri annually attracts large numbers of people to enjoy the recreational benefits of the cool springs and clear rivers. However, in 1955, rich mineral deposits were discovered in this area and by 1962 a rich lead-zinc ore belt was found to extend for approximately thirty-six miles almost due south from Viburnum, Missouri, through Iron and Reynolds Counties. The name given this new ore district was the Viburnum Trend or the 'New Lead Belt'.Project # A-021-MO and B-021-M

Development and validation of the POSITIVES scale (postsecondary information technology scale)

"Final report presented to the Canadian Council on Learning"Titre de l'écran-titre (visionné le 6 août 2009).Également disponible en format papier.Comprend des références bibliographiques

Microwave observations of spinning dust emission in NGC6946

We report new cm-wave measurements at five frequencies between 15 and 18GHz of the continuum emission from the reportedly anomalous "region 4" of the nearby galaxy NGC6946. We find that the emission in this frequency range is significantly in excess of that measured at 8.5GHz, but has a spectrum from 15-18GHz consistent with optically thin free-free emission from a compact HII region. In combination with previously published data we fit four emission models containing different continuum components using the Bayesian spectrum analysis package radiospec. These fits show that, in combination with data at other frequencies, a model with a spinning dust component is slightly preferred to those that possess better-established emission mechanisms.Comment: submitted MNRA

Planck intermediate results. XV. A study of anomalous microwave emission in Galactic clouds

Anomalous microwave emission (AME) is believed to be due to electric dipole radiation from small spinning dust grains. The aim of this paper is a statistical study of the basic properties of AME regions and the environment in which they emit. We used WMAP and Planck maps, combined with ancillary radio and IR data, to construct a sample of 98 candidate AME sources, assembling SEDs for each source using aperture photometry on 1°-smoothed maps from 0.408 GHz up to 3000 GHz. Each spectrum is fitted with a simple model of free-free, synchrotron (where necessary), cosmic microwave background (CMB), thermal dust, and spinning dust components. We find that 42 of the 98 sources have significant (>5σ) excess emission at frequencies between 20 and 60 GHz. An analysis of the potential contribution of optically thick free-free emission from ultra-compact H ii regions, using IR colour criteria, reduces the significant AME sample to 27 regions. The spectrum of the AME is consistent with model spectra of spinning dust. Peak frequencies are in the range 20−35 GHz except for the California nebula (NGC 1499), which appears to have a high spinning dust peak frequency of (50 ± 17) GHz. The AME regions tend to be more spatially extended than regions with little or no AME. The AME intensity is strongly correlated with the sub-millimetre/IR flux densities and comparable to previous AME detections in the literature. AME emissivity, defined as the ratio of AME to dust optical depth, varies by an order of magnitude for the AME regions. The AME regions tend to be associated with cooler dust in the range 14−20 K and an average emissivity index, βd, of +1.8, while the non-AME regions are typically warmer, at 20−27 K. In agreement with previous studies, the AME emissivity appears to decrease with increasing column density. This supports the idea of AME originating from small grains that are known to be depleted in dense regions, probably due to coagulation onto larger grains. We also find a correlation between the AME emissivity (and to a lesser degree the spinning dust peak frequency) and the intensity of the interstellar radiation field, G0. Modelling of this trend suggests that both radiative and collisional excitation are important for the spinning dust emission. The most significant AME regions tend to have relatively less ionized gas (free-free emission), although this could be a selection effect. The infrared excess, a measure of the heating of dust associated with H ii regions, is typically >4 for AME sources, indicating that the dust is not primarily heated by hot OB stars. The AME regions are associated with known dark nebulae and have higher 12 μm/25 μm ratios. The emerging picture is that the bulk of the AME is coming from the polycyclic aromatic hydrocarbons and small dust grains from the colder neutral interstellar medium phase. Reproduced with permission from Astronomy & Astrophysics, © ESO 201

Infection prevention and control in the tropics

Tropical settings present unique challenges to the practice of infection prevention and control. These are multi-faceted due to differences in the climate, culture, social, and political milieu of low- and middle-income countries situated in the tropics, as well as the lack of resources. The emergence of communicable diseases and low vaccination coverage also lead to nosocomial augmentation of community outbreaks, further increasing the economic burden of hospital management. Addressing these challenges requires innovative, low-cost, and tailored solutions suited to the tropical environment

Mechanism of gating and ion conductivity of a possible tetrameric pore in Aquaporin-1

Copyright © 2006 Elsevier Ltd All rights reserved.While substrate permeation through monomeric pores of aquaporins is well characterized, little is known about the possible tetrameric pore. AQP1 has been suggested to function as an ion channel upon cGMP activation, although this idea has been controversial. Taking a theoretical and experimental approach, we demonstrate that the current might arise through the tetrameric pore and propose a plausible mechanism for conduction and gating. In response to simulated ion permeation, immediate hydration of the putative central pore was facilitated by moderate conformational changes of pore-lining residues. cGMP is found to interact with an unusually arginine-rich, cytoplasmic loop (loop D) facilitating its outward motion, which is hypothesized to trigger the opening of a cytoplasmic gate. Physiological analyses of wild-type AQP1 and a designed mutant in which two arginines of the gating loop are replaced by alanine provide experimental support for identifying a key component of the proposed mechanism.Jin Yu, Andrea J. Yool, Klaus Schulten and Emad Tajkhorshi