314 research outputs found

    ENIGMA-anxiety working group: Rationale for and organization of large-scale neuroimaging studies of anxiety disorders

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    Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA‐Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. This paper elaborates on the concepts and methods informing the work of the working group to date, and describes the initial approach of the four subgroups studying generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobia. At present, the ENIGMA‐Anxiety database contains information about more than 100 unique samples, from 16 countries and 59 institutes. Future directions include examining additional imaging modalities, integrating imaging and genetic data, and collaborating with other ENIGMA working groups. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA‐Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders

    Experimental evaluation of the dynamic seasonal streamflow forecasting approach

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    The primary focus of this experimental evaluation project is to answer the key question: is it possible to provide accurate and reliable seasonal streamflow forecasts using the dynamic hydrologic modelling approach? To address this issue, this experimental project evaluated the performance of the dynamic modelling approach to key catchments in the Murray-Darling Basin, where statistical seasonal streamflow forecasts are currently available.Tuteja NK, Shin D, Laugesen R, Khan U, Shao Q, Wang E, Li M, Zheng H, Kuczera G, Kavetski D, Evin G, Thyer M, MacDonald A, Chia T & Le

    The Effect of Auditory Distraction on the Useful Field of View in Hearing Impaired Individuals and its implications for driving

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    This study assessed whether the increased demand of listening in hearing impaired individuals exacerbates the detrimental impact of auditory distraction on a visual task (useful field of view test), relative to normally hearing listeners. Auditory distraction negatively affects this visual task, which is linked with various driving performance outcomes. Hearing impaired and normally hearing participants performed useful field of view testing with and without a simultaneous listening task. They also undertook a cognitive test battery. For all participants, performing the visual and auditory tasks together reduced performance on each respective test. For a number of subtests, hearing impaired participants showed poorer visual task performance, though not to a statistically significant extent. Hearing impaired participants were significantly poorer at a reading span task than normally hearing participants and tended to score lower on the most visually complex subtest of the visual task in the absence of auditory task engagement. Useful field of view performance is negatively affected by auditory distraction, and hearing loss may present further problems, given the reductions in visual and cognitive task performance suggested in this study. Suggestions are made for future work to extend this study, given the practical importance of the findings

    Letters to the Editor

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