Trying the stuff of creation: biblicism, tragedy, and romance in the southern fiction of Cormac McCarthy

This essay presents an analysis of the religious and philosophical ideas present in the early fiction of the contemporary American writer, Cormac McCarthy. It is intended as an intervention into the controversial debate within McCarthy scholarship concerning how the perceptibly ‘religious’ nature of the author’s fictions may be described according to recognised and coherent confessions or perspectives. I argue that McCarthy’s fictions cannot be shown to conform to any particular theological or metaphysical system without significant remainder on account of their being essentially heterogeneous in their construction; and that their religious ‘significance’ lies not in their communication of a positive message, but in the presentation of what is at stake in the contrary interpretations that they uphold. I argue that the essential heterogeneity of McCarthy’s fiction is a development of the author’s reception of the complex aesthetic of Herman Melville’s Moby-Dick and the posture of serious and searching scepticism which that touchstone of American literature presents. The peculiar aesthetic of Moby-Dick alloys the Hellenic and Hebraic imagination, creating a synthesis of the concrete images of mythical and biblical literature, and of the narrative patterns that are native to tragedy and to romance. The effect of this complex is a literary mode that performs a suspension or opposition between a shapeless, circular, mythical world, and the created and teleological worldview declared by the biblical religions. I demonstrate how McCarthy takes up and imaginatively revises this complex of ideas in three novels (Outer Dark, Child of God, and Blood Meridian) in terms of their relation to the motifs and tropes of tragedy and romance, with a particular concern for their relation to the literature of katabasis, or spiritual and metaphysical ‘descent’. The three novels I have selected demonstrate a consistent and developing approach to McCarthy’s examination of various accounts of the material and physical nature of the world. My analysis sets out how the author’s aesthetic and narrative strategy describes an opposition between a view that is attributable to a broadly defined atheistic naturalism on the one hand, and notions of a teleologically orientated creation that is concordant with the transcendent God of the biblical religions on the other. In providing this description, I interpret how McCarthy uses this Melvillean pattern to test the viability of such oppositions, and in doing so, argue that the author’s distinctive vision should be understood as an apophatic mode that is appropriate to a faith ‘beyond the forms of faith’

Prolonged lymphatic leak after retroperitoneal lymph node dissection: a case report

<p>Abstract</p> <p>Introduction</p> <p>Persistent lymphatic drainage following retroperitoneal lymph node dissection for testicular tumor is an uncommon complication.</p> <p>Case presentation</p> <p>We describe a 21-year old man of Caucasian origin who had metastatic non-seminomatous germ cell tumor of the testis, and underwent retroperitoneal lymph node dissection, nephrectomy and partial inferior vena cava excision for a residual mass. The patient subsequently developed persistent lymphatic drainage causing foot drop that eventually responded to conservative medical and surgical measures.</p> <p>Conclusion</p> <p>This postoperative condition usually responds well to conservative measures but has the potential for serious morbidity if it is not managed appropriately.</p

Towards distributed diagnosis of the Tennessee Eastman process benchmark

A distributed hybrid strategy is outlined for the isolation of faults and disturbances in the Tennessee Eastman process, which would build on existing structures for distributed control systems, so should be easy to implement, be cheap and be widely applicable. The main emphasis in the paper is on one component of the strategy, a steady-state-based approach. Results obtained by applying this approach are presented and knowledge limitations are discussed. In particular a way in which a knowledge-base might evolve to improve isolation capabilities is suggested and the role of the operator is briefly discussed

Trying the stuff of creation: biblicism, tragedy, and romance in the southern fiction of Cormac McCarthy

This essay presents an analysis of the religious and philosophical ideas present in the early fiction of the contemporary American writer, Cormac McCarthy. It is intended as an intervention into the controversial debate within McCarthy scholarship concerning how the perceptibly ‘religious’ nature of the author’s fictions may be described according to recognised and coherent confessions or perspectives. I argue that McCarthy’s fictions cannot be shown to conform to any particular theological or metaphysical system without significant remainder on account of their being essentially heterogeneous in their construction; and that their religious ‘significance’ lies not in their communication of a positive message, but in the presentation of what is at stake in the contrary interpretations that they uphold. I argue that the essential heterogeneity of McCarthy’s fiction is a development of the author’s reception of the complex aesthetic of Herman Melville’s Moby-Dick and the posture of serious and searching scepticism which that touchstone of American literature presents. The peculiar aesthetic of Moby-Dick alloys the Hellenic and Hebraic imagination, creating a synthesis of the concrete images of mythical and biblical literature, and of the narrative patterns that are native to tragedy and to romance. The effect of this complex is a literary mode that performs a suspension or opposition between a shapeless, circular, mythical world, and the created and teleological worldview declared by the biblical religions. I demonstrate how McCarthy takes up and imaginatively revises this complex of ideas in three novels (Outer Dark, Child of God, and Blood Meridian) in terms of their relation to the motifs and tropes of tragedy and romance, with a particular concern for their relation to the literature of katabasis, or spiritual and metaphysical ‘descent’. The three novels I have selected demonstrate a consistent and developing approach to McCarthy’s examination of various accounts of the material and physical nature of the world. My analysis sets out how the author’s aesthetic and narrative strategy describes an opposition between a view that is attributable to a broadly defined atheistic naturalism on the one hand, and notions of a teleologically orientated creation that is concordant with the transcendent God of the biblical religions on the other. In providing this description, I interpret how McCarthy uses this Melvillean pattern to test the viability of such oppositions, and in doing so, argue that the author’s distinctive vision should be understood as an apophatic mode that is appropriate to a faith ‘beyond the forms of faith’

Uptake of macromolecules by cercariae during skin penetration and transformation to schistosomula (Schistosoma mansoni)

Here, we observed the uptake of membrane-impermeant molecules by cercariae as they penetrate the skin and are transformed into schistosomula. We propose that membrane-impermeant molecules, Lucifer Yellow, Propidium iodide and Hoechst 33258 enter the parasite through both thenephridiopore and the surface membrane and then diffuse throughout the body of the parasite. We present a hypothesis that the internal cells of the body of the schistosomulum represent a new host-parasite interface, at which skin-derived growth factors may stimulate receptors on internal membranes during transformation of the cercariae into the schistosomulum

Characterizations of tropospheric turbulence and stability layers from aircraft observations

[1] Velocity, temperature, and specific humidity data collected by aircraft at 20-Hz resolution are analyzed for stability and turbulence parameters. Over 100 vertical profiles (mostly over the ocean) with a total of over 300 km in vertical airspace sampled are used. The compiled statistics show that anisotropy in the velocity fluctuations prevail down to the smallest spatial separations measured. A partitioning of convective versus dynamical instability indicates that in the free troposphere, the ratio of shear-produced turbulence to convectively produced turbulence increases from roughly 2:1 for weak turbulence (ϵ 10⁻⁴ m² s⁻³). For the boundary layer, this ratio is close to 1:1 for weak turbulence and roughly 2:1 for strong turbulence. There is also a correlation between the strength of the vertical shear in horizontal winds and the turbulence intensity. In the free troposphere the turbulence intensity is independent of the degree of static stability, whereas in the boundary layer the turbulence intensity increases with a fall in static stability. Vertical humidity gradients correlate with static stability for strong humidity gradients, which supports the basic notion that stable layers impede vertical mixing of trace gases and aerosols. Vertical shear correlates with vertical humidity gradient, so it appears that the effect of differential advection creating tracer gradients dominates the effect of differential advection destroying tracer gradients through shear-induced turbulence.United States. National Aeronautics and Space Administration (Grant NCC1-415)United States. National Aeronautics and Space Administration (Grant NAG1-2306

Comparison of adverse events associated with different spacers used with non-extrafine beclometasone dipropionate for asthma

The authors would like to extend their acknowledgement to Dr. Antony Hardjojo for proof-reading this manuscript. This study is funded by Chiesi Limited. All relevant data are within the paper and the supporting information files. The dataset supporting the conclusions of this article was derived from the UK Optimum Patient Care Research Database (www.opcrd.co.uk). We do not have permission to give public access to these databases; however, researchers may request access for their own purposes. Request for access to OCPRD can be made via the OCPRD website (https://opcrd.co.uk/our-database/data-requests/) or via the enquiries email [email protected] reviewedPublisher PD

Prospective Study of Antibiotic Prophylaxis for Prostate Biopsy Involving >1100 Men

We aimed to compare infection rates for two 3-day antibiotic prophylaxis regimens for transrectal ultrasound-guided prostate biopsy (TRUSgbp) and demonstrate local microbiological trends. In 2008, 558 men and, in 2009, 625 men had TRUSgpb. Regimen 1 (2008) comprised 400 mg Ofloxacin immediately before biopsy and 200 mg 12-hourly for 3 days. Regimen 2 (2009) comprised Ofloxacin 200 mg 12-hourly for 3 days commencing 24 hours before biopsy. 20/558 (3.6%) men had febrile episodes with regimen 1 and 10/625 (1.6%) men with regimen 2 (P = 0.03). E. coli was the most frequently isolated organism. Overall, 7/13 (54%) of positive urine cultures were quinolone resistant and (5/13) 40% were multidrug resistant. Overall, 5/9 (56%) patients with septicaemia were quinolone resistant. All patients were sensitive to Meropenem. There was 1 (0.2%) death with regimen 1. Commencing Ofloxacin 24 hours before TRUSgpb reduced the incidence of febrile episodes significantly. We observed the emergence of quinolone and multidrug-resistant E. coli. Meropenem should be considered for unresolving sepsis