A combinatorial approach to angiosperm pollen morphology

Angiosperms (flowering plants) are strikingly diverse. This is clearly expressed in the morphology of their pollen grains, which are characterized by enormous variety in their shape and patterning. In this paper, I approach angiosperm pollen morphology from the perspective of enumerative combinatorics. This involves generating angiosperm pollen morphotypes by algorithmically combining character states and enumerating the results of these combinations. I use this approach to generate 3 643 200 pollen morphotypes, which I visualize using a parallel-coordinates plot. This represents a raw morphospace. To compare real-world and theoretical morphologies, I map the pollen of 1008 species of Neotropical angiosperms growing on Barro Colorado Island (BCI), Panama, onto this raw morphospace. This highlights that, in addition to their well-documented taxonomic diversity, Neotropical rainforests also represent an enormous reservoir of morphological diversity. Angiosperm pollen morphospace at BCI has been filled mostly by pollen morphotypes that are unique to single plant species. Repetition of pollen morphotypes among higher taxa at BCI reflects both constraint and convergence. This combinatorial approach to morphology addresses the complexity that results from large numbers of discrete character combinations and could be employed in any situation where organismal form can be captured by discrete morphological characters

Heartbeat stars and the ringing of tidal pulsations

With the advent of high precision photometry from satellites such as Kepler and CoRoT, a whole new layer of interesting and astounding astronomical objects has been revealed: heartbeat stars are an example of such objects. Heartbeat stars are eccen- tric ellipsoidal variables that undergo strong tidal interactions when the stars are almost in contact at the time of closest approach. These interactions deform of the stars and cause a notable light curve variation in the form of a tidal pulse. A subset of these objects (∼20%) show prominent tidally induced pulsations: pulsations forced by the binary orbit. We now have a fully functional code that models binary star features (using phoebe) and stellar pulsations simultaneously, enabling a complete and accurate heartbeat star model to be determined. In this paper we show the results of our new code, which uses emcee, a variant of mcmc, to generate a full set of stellar parameters. We further highlight the interesting features of KIC 8164262, including its tidally induced pulsations and resonantly locked pulsations

Understanding and supporting adolescents' mental touchness in an educational context

This study sought to explore the concept of mental toughness (comprising the attributes challenge, commitment, control and confidence) from the perceptions of adolescents, to better understand their views on these attributes and the extent to which each were regarded as important within an educational setting. In total, 54 adolescents (31 female) aged 12-17 participated. Focus group interviews (n = 15, average group size 3-4) were conducted, audio-recorded and transcribed verbatim. Data were analysed using the principles of abbreviated grounded theory. The students’ views are discussed with reference to relevant psychological theory and literature and implications for teachers interested in encouraging these positive psychological attributes among adolescents are discussed

A review of clinical decision-making: Models and current research

Aims and objectives: The aim of this paper was to review the current literature with respect to clinical decision-making models and the educational application of models to clinical practice. This was achieved by exploring the function and related research of the three available models of clinical decision making: information processing model, the intuitive-humanist model and the clinical decision making model. Background: Clinical decision-making is a unique process that involves the interplay between knowledge of pre-existing pathological conditions, explicit patient information, nursing care and experiential learning. Historically, two models of clinical decision making are recognised from the literature; the information processing model and the intuitive-humanist model. The usefulness and application of both models has been examined in relation the provision of nursing care and care related outcomes. More recently a third model of clinical decision making has been proposed. This new multidimensional model contains elements of the information processing model but also examines patient specific elements that are necessary for cue and pattern recognition. Design: Literature review Methods: Evaluation of the literature generated from MEDLINE, CINAHL, OVID, PUBMED and EBESCO systems and the Internet from 1980 – November 2005

Emeishan Basalts, SW China: Reappraisal of the formation's type area stratigraphy and a discussion of its significance as a large igneous province

The late Permian Emeishan Basalt Formation of SW China is one of Earth's LIPs (large igneous provinces), yet its basic geology remains poorly documented. Recent work on sections close to the type area in Sichuan Province enable us in part to rectify this. Descriptions of the formation and associated units at two areas, one on the lower flanks of Mt Emei and another from a series of outercrops in Ebian County, 50-70 km to the SW, are presented. The basalt pile is 180-270 m thick and in both areas comprises 12 flows that were erupted in relatively quick succession. It rests conformably upon shallow-marine limestones/lignites suggesting emplacement close to sea level. The upper half of the youngest basalt was intensively weathered, but not eroded, prior to it being conformably succeeded by complex body of rocks c. 30 m thick, that includes thin basalts, pyroclastic rocks, tuffs and organic-rich terrestrial sediments. This unit, which has previously been described as a sedimentary package, presumably because intense weathering has obscured the primary lithological fabric in key outcrops, is considered to mark the volcanic waning phase. Uppermost Permian and Triassic terrestrial sediments conformably overlie the terminal volcanic rocks. The sub-regional stratigraphy is compared, as best it can be, with that described from two sections 400 km to the SE; one section matches reasonably well, the other does not, indicating that regional correlations need to be developed carefully. The information is discussed in the context of LIP generator models; several key features of the Emeishan Basalt terrain are at odds with those commonly encountered in LIP's. The most important conclusion is that the unit marks a prematurely terminated system in which full bloodied rifting leading to the development of an ocean basin never started.published_or_final_versio

Temporal changes in rock uplift rates of folds in the foreland of the Tian Shan and the Pamir from geodetic and geologic data

Understanding the evolution of continental deformation zones relies on quantifying spatial and temporal changes in deformation rates of tectonic structures. Along the eastern boundary of the Pamir‐Tian Shan collision zone, we constrain secular variations of rock uplift rates for a series of five Quaternary detachment‐ and fault‐related folds from their initiation to the modern day. When combined with GPS data, decomposition of interferometric synthetic aperture radar time series constrains the spatial pattern of surface and rock uplift on the folds deforming at decadal rates of 1–5 mm/yr. These data confirm the previously proposed basinward propagation of structures during the Quaternary. By fitting our geodetic rates and previously published geologic uplift rates with piecewise linear functions, we find that gradual rate changes over >100 kyr can explain the interferometric synthetic aperture radar observations where changes in average uplift rates are greater than ~1 mm/yr among different time intervals (~10¹, 10⁴‾⁵, and 10⁵‾⁶ years)

Bistability in Apoptosis by Receptor Clustering

Apoptosis is a highly regulated cell death mechanism involved in many physiological processes. A key component of extrinsically activated apoptosis is the death receptor Fas, which, on binding to its cognate ligand FasL, oligomerize to form the death-inducing signaling complex. Motivated by recent experimental data, we propose a mathematical model of death ligand-receptor dynamics where FasL acts as a clustering agent for Fas, which form locally stable signaling platforms through proximity-induced receptor interactions. Significantly, the model exhibits hysteresis, providing an upstream mechanism for bistability and robustness. At low receptor concentrations, the bistability is contingent on the trimerism of FasL. Moreover, irreversible bistability, representing a committed cell death decision, emerges at high concentrations, which may be achieved through receptor pre-association or localization onto membrane lipid rafts. Thus, our model provides a novel theory for these observed biological phenomena within the unified context of bistability. Importantly, as Fas interactions initiate the extrinsic apoptotic pathway, our model also suggests a mechanism by which cells may function as bistable life/death switches independently of any such dynamics in their downstream components. Our results highlight the role of death receptors in deciding cell fate and add to the signal processing capabilities attributed to receptor clustering.Comment: Accepted by PLoS Comput Bio

Social Entrepreneurship—Building Sustainability Through Business Models and Measurement of Social Impact

Social entrepreneurshipSocial entrepreneurship is gaining unprecedented momentum in the recent years and it is overwhelming to learn how social entrepreneurs are able to create both social and economic value overcoming all odds and sustain and grow their ventures. Social enterprise can be a for-profit or a not-for- profit venture in their constitution. This research study presents a comparative case analysis of four social ventures two of them are not-for-profit organisations and depend mainly on philanthropic partners for funding. The other two are for-profit social venturesNot-for-profit Social venture and create products and services which are commercially viable. Three of the founders are Ashoka fellows and one is a national award winning social entrepreneur, all based in India. Irrespective of the nature of enterprise, developing a viable business modelBusiness model is crucial for the sustainabilitySustainability of the venture. Analysis of these organisations’ business models reveals different patterns. The findings suggest that successful social entrepreneurial organisations proactively create their own ways to partner with multiple stakeholders who share their social visionVision ; deploy resources effectively as an integral part of the business model; and integrate the target group into the social value network

Brownian bridges to submanifolds

We introduce and study Brownian bridges to submanifolds. Our method involves proving a general formula for the integral over a submanifold of the minimal heat kernel on a complete Riemannian manifold. We use the formula to derive lower bounds, an asymptotic relation and derivative estimates. We also see a connection to hypersurface local time. This work is motivated by the desire to extend the analysis of path and loop spaces to measures on paths which terminate on a submanifold