Herps at height: Records of seven species utilizing the upper canopy in northwestern Ecuador

Canopy science has not developed as rapidly as other fields due to the inherent difficulty of accessing this ecosystem. Using a blend of industrial and arboricultural rope access techniques, we confirmed occurrences in the canopy of five reptile and two amphibian species in the Chocóan forests of northwestern Ecuador. RESUMEN La investigación en el dosel no se ha desarrollado con la misma velocidad que otras áreas debido a la inaccesibilidad de este ecosistema. Utilizando una combinación de técnicas de acceso con cuerdas de arboricultura e industria, confirmamos la ocurrencia del dosel de cinco especies de reptiles y dos especies de anfibios en los bosques del Chocó del noroccidente del Ecuador

Next steps in children and young people’s research, participation and protection from the perspective of young researchers

Purpose The purpose of this paper is to explore young researchers perspectives on children and young people’s research, participation and protection. Design/methodology/approach The paper is co-authored by young people and academics involved in a young researcher group. This paper provides a brief introduction from the young researchers and some academic context to their work, then the young researcher group’s contribution. Their contribution is followed by a brief discussion of the issues they raise in the light of current academic debate. Findings This paper contains our critical reflection on participation and protection. Originality/value The paper presents a unique contribution capturing children and young people’s perspectives on the journal’s theme and other contributions to i

Seasonal Heat Acclimatisation in Healthy Adults:A Systematic Review

BACKGROUND: Physiological heat adaptations can be induced following various protocols that use either artificially controlled (i.e. acclimation) or naturally occurring (i.e. acclimatisation) environments. During the summer months in seasonal climates, adequate exposure to outdoor environmental heat stress should lead to transient seasonal heat acclimatisation. OBJECTIVES: The aim of the systematic review was to assess the available literature and characterise seasonal heat acclimatisation during the summer months and identify key factors that influence the magnitude of adaptation. ELIGIBILITY CRITERIA: English language, full-text articles that assessed seasonal heat acclimatisation on the same sample of healthy adults a minimum of 3 months apart were included. DATA SOURCES: Studies were identified using first- and second-order search terms in the databases MEDLINE, SPORTDiscus, CINAHL Plus with Full Text, Scopus and Cochrane, with the last search taking place on 15 July 2021. RISK OF BIAS: Studies were independently assessed by two authors for the risk of bias using a modified version of the McMaster critical review form. DATA EXTRACTION: Data for the following outcome variables were extracted: participant age, sex, body mass, height, body fat percentage, maximal oxygen uptake, time spent exercising outdoors (i.e. intensity, duration, environmental conditions), heat response test (i.e. protocol, time between tests), core temperature, skin temperature, heart rate, whole-body sweat loss, whole-body and local sweat rate, sweat sodium concentration, skin blood flow and plasma volume changes. RESULTS: Twenty-nine studies were included in this systematic review, including 561 participants across eight countries with a mean summer daytime wet-bulb globe temperature (WBGT) of 24.9 °C (range: 19.5–29.8 °C). Two studies reported a reduction in resting core temperature (0.16 °C; p < 0.05), 11 reported an increased sweat rate (range: 0.03–0.53 L·h(−1); p < 0.05), two observed a reduced heart rate during a heat response test (range: 3–8 beats·min(−1); p < 0.05), and six noted a reduced sweat sodium concentration (range: − 22 to − 59%; p < 0.05) following summer. The adaptations were associated with a mean summer WBGT of 25.2 °C (range: 19.6–28.7 °C). LIMITATIONS: The available studies primarily focussed on healthy male adults and demonstrated large differences in the reporting of factors that influence the development of seasonal heat acclimatisation, namely, exposure time and duration, exercise task and environmental conditions. CONCLUSIONS: Seasonal heat acclimatisation is induced across various climates in healthy adults. The magnitude of adaptation is dependent on a combination of environmental and physical activity characteristics. Providing environmental conditions are conducive to adaptation, the duration and intensity of outdoor physical activity, along with the timing of exposures, can influence seasonal heat acclimatisation. Future research should ensure the documentation of these factors to allow for a better characterisation of seasonal heat acclimatisation. PROSPERO REGISTRATION: CRD42020201883. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40279-022-01677-0

The Danish 22q11 research initiative

Background: Neurodevelopmental brain disorders such as schizophrenia, autism and attention deficit hyperactivity disorder are complex disorders with heterogeneous etiologies. Schizophrenia and autism are difficult to treat and often cause major individual suffering largely owing to our limited understanding of the disease biology. Thus our understanding of the biological pathogenesis needs to be substantiated to enable development of more targeted treatment options with improved efficacy. Insights into the pre-morbid disease dynamics, the morbid condition and the underlying biological disease mechanisms may come from studies of subjects with homogenous etiologies. Breakthroughs in psychiatric genetics have shown that several genetic anomalies predispose for neurodevelopmental brain disorders. We have established a Danish research initiative to study the common microdeletion at chromosome 22q11.2, which is one of the genetic anomalies that confer high risk of schizophrenia, autism and attention deficit hyperactivity disorder. Methods/design: The study applies a "cause-to-outcome" strategy to identify pre-morbid pathogenesis and underlying biological disease mechanisms of psychosis and secondarily the morbid condition of autism and attention deficit hyperactivity disorder. We use a population based epidemiological design to inform on disease prevalence, environmental risk factors and familial disposition for mental health disorders and a case control study design to map the functional effects across behavioral and neurophysiological traits of the 22q11 deletion in a recruited sample of Danish individuals. Discussion: Identification of predictive pre-morbid clinical, cognitive, functional and structural brain alterations in 22q11 deletion carriers may alter current clinical practice from symptomatic therapy of manifest mental illness into early intervention strategies, which may also be applicable to at risk subjects without known etiology. Hopefully new insights into the biological disease mechanisms, which are mandatory for novel drug developments, can improve the outcome of the pharmacological interventions in psychiatry

Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study

Purpose: Delirium is a neuropsychiatric disorder delineated by an acute change in cognition, attention, and consciousness. It is common, particularly in older adults, but poorly recognised. Frailty is the accumulation of deficits conferring an increased risk of adverse outcomes. We set out to determine how severity of frailty, as measured using the CFS, affected delirium rates, and recognition in hospitalised older people in the United Kingdom. Methods: Adults over 65 years were included in an observational multi-centre audit across UK hospitals, two prospective rounds, and one retrospective note review. Clinical Frailty Scale (CFS), delirium status, and 30-day outcomes were recorded. Results: The overall prevalence of delirium was 16.3% (483). Patients with delirium were more frail than patients without delirium (median CFS 6 vs 4). The risk of delirium was greater with increasing frailty [OR 2.9 (1.8–4.6) in CFS 4 vs 1–3; OR 12.4 (6.2–24.5) in CFS 8 vs 1–3]. Higher CFS was associated with reduced recognition of delirium (OR of 0.7 (0.3–1.9) in CFS 4 compared to 0.2 (0.1–0.7) in CFS 8). These risks were both independent of age and dementia. Conclusion: We have demonstrated an incremental increase in risk of delirium with increasing frailty. This has important clinical implications, suggesting that frailty may provide a more nuanced measure of vulnerability to delirium and poor outcomes. However, the most frail patients are least likely to have their delirium diagnosed and there is a significant lack of research into the underlying pathophysiology of both of these common geriatric syndromes

A strategy framework to facilitate spatially enabled Victoria

This is a preprint of a paper from GSDI 11 World Conference 15-19 June 2009 published by Global Spatial Data Infrastructure Association http://www.gsdi.org/gsdiConferencesSpatial Information is at a critical turning point in its development. More people are using it for a wider range of purposes, including social networking; technology is changing the way we communicate with each other; there are new ways of thinking about ‘location’; and big corporate players are entering the market and are starting to drive standards. At the same time, all levels of government, business and the community face significant challenges in producing and using products and services in environmentally and socially sustainable ways. Spatial information has an integral part to play in developing solutions to these challenges. But this cannot be achieved without a clear strategy and a framework that harnesses everyone’s skills and expertise. Victoria is fast being recognised as a leader in many aspects of State SDI development in Australia and internationally. The Victorian Spatial Council – which is the peak body that provides a coordinated approach to policy and development and management of spatial information – has recently painted the emerging landscape for spatial information in Victoria. Through the Victorian Spatial Information Strategy 2008-2010 it highlights some of the changes occurring in spatial information and technology and the key challenges they pose, and sets the broad themes for facilitating the whole spatial information community’s participation in that landscape. VSIS is a basis for delivering spatially enabled Victoria. At the same time, it considers that spatial information should be seen as part of the wider information resource created by and available to society. It presents a challenging agenda and the strategic framework it sets out lays the foundation for fulfilling the promises that are held out by the developments it describes. This paper aims to present and discuss VSIS, its development process and its role in connecting all levels of government, the private sector, utilities, academia, the professions and a wider community from a spatial data perspective. The paper starts with a discussion on the importance of having a spatial information framework in the context of spatially enabled society and then discusses the central role VSIS plays in facilitating the spatially enabled vision in Victoria. The paper then highlights a range of activities and processes to be undertaken across all disciplines and sectors to facilitate framework development. This includes aspects of design, creation, governance and processes involved in developing an enabling platform, and the overall relations between different challenges to facilitate spatial data activities. The results and lessons learned from the development of the strategy can be used and applied in other jurisdictions, at both national and global levels.15-19 June 200