Alien Registration- Thomas, Muriel (Waterville, Kennebec County)

https://digitalmaine.com/alien_docs/15077/thumbnail.jp

Étude Comparée sur la Réussite Universitaire Québec-Ontario pour la Période 1994-1996

The knowledge-based economy has emphasised the role of human capital and the relevance of formal education. This study analyses university achievement and gives a quantitative description of Quebec and Ontario university systems. Comparative differences by educational levels and fields of studies are presented and discussed within the context of the labour market. Les préoccupations actuelles de l'économie du savoir ont mis en valeur l'importance du capital humain et par conséquent l'importance de l'instruction. Cette étude analyse la réussite universitaire et permet de décrire d'un point de vue quantitatif les systèmes universitaires québécois et ontariens. Le point de vue qualitatif est également traité à travers l'analyse des différences par domaine d'étude et par discipline.university achievement, educational levels, fields of studies, rate of return, sectors of activity, réussite universitaire, baccalauréat, maîtrise, doctorat, domaine d'étude, matières, postsecondaire, écarts, taux de rendement, secteur d'activité

Abyssal fauna of polymetallic nodule exploration areas, eastern Clarion-Clipperton Zone, central Pacific Ocean: Annelida: Spionidae and Poecilochaetidae

This paper represents a continuation of taxonomic publications on the benthic fauna of polymetallic nodule fields in the eastern Clarion-Clipperton Zone (CCZ) using material collected during baseline environmental survey work targeting two exploration contract areas (“UK-1” and “OMS”) and one Area of Particular Environmental Interest, “APEI-6.” Families Poecilochaetidae Hannerz, 1956 and Spionidae Grube, 1850 of the annelid suborder Spioniformia were studied here. Taxonomic data are presented for 25 species from 98 records as identified by a combination of morphological and genetic approaches. Although sub-optimal morphological condition can prevent new species being formally described, it is essential that morphological, molecular, and voucher data are made available for future surveys. Descriptions of two new species—Poecilochaetus brenkei sp. nov. and Laonice shulseae sp. nov.—increase the number of formally described new annelid species from the areas targeted in this study to 15 and CCZ-wide to 46. We also discuss the commonly reported “cosmopolitan” deep-sea spionid Aurospio dibranchiata Maciolek, 1981, which we show represents several genetically distinct species (three of these from CCZ area alone) but without reliable morphological characters to separate them. Molecular data provide evidence that 15 out of 25 species reported here have a wide distribution within the eastern CCZ and that Aurospio sp. “NHM_2186” and the known species Prionospio amarsupiata Neal & Altamira in Paterson et al. 2016 may be cosmopolitan. Lastly, the molecular data provide insights into relationships within Spioniformia, suggesting that both Poecilochaetidae and Trochochaetidae belong within Spionidae.publishedVersio

La construcción del sujeto ético a partir del análisis comparativo de la pedagogía socrática y la pedagogía sedaniana.

El proyecto de investigación pretende establecer los fundamentos pedagógicos de la construcción de sujeto ético a partir del análisis comparativo de la pedagogía socrática de la pregunta y la pedagogía sedaniana de la respuesta. Para ello, se pretende analizar los presupuestos filosóficos y pedagógicos del método de la ironía y mayéutico de la filosofía socrática, identificando los valores y principios de la pregunta y el diálogo como disposición pedagógica indispensable en la formación del sujeto y el conocimiento de sí. Por otro lado, se busca examinar los rasgos fundamentales de la propuesta de José de Jesús Sedano en su pedagogía de la respuesta, retomando el principio de la responsabilidad y el compromiso social como los derroteros para la participación ciudadana y la conciencia democrática. Este diálogo filosófico y pedagógico lleva a la argumentación sobre la importancia de la formación de sí mismo como principio de la construcción del sujeto ético, autónomo, comprometido, responsable, esperanzador, cuyo espíritu argumentativo le permite el libre pensamiento y la conciencia de estudio, logrando así una nueva perspectiva cultural y una mirada crítica de sí mismo y de la sociedad

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice

Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known. Methods: To explore the importance of cholesterol homeostasis for asthma, we investigated the contribution of LXR activity in an ovalbumin- and a house dust mite-driven eosinophilic asthma mouse model. Results: In both models, airway inflammation, airway hyper-reactivity, and goblet cell hyperplasia were reduced in mice deficient for both LXR and LXR isoforms (LXR-/--/-) as compared to wild-type mice. Inversely, treatment with the LXR agonist GW3965 showed increased eosinophilic airway inflammation. LXR activity contributed to airway inflammation through promotion of type 2 cytokine production as LXR-/--/- mice showed strongly reduced protein levels of IL-5 and IL-13 in the lungs as well as reduced expression of these cytokines by CD4(+) lung cells and lung-draining lymph node cells. In line herewith, LXR activation resulted in increased type 2 cytokine production by the lung-draining lymph node cells. Conclusions: In conclusion, our study demonstrates that the cholesterol regulator LXR acts as a positive regulator of eosinophilic asthma in mice, contributing to airway inflammation through regulation of type 2 cytokine production

Contribution of plasmid-encoded peptidase S8 (PrtP) to adhesion and transit in the gut of Lactococcus lactis IBB477 strain

The ability of Lactococcus lactis to adhere to the intestinal mucosa can potentially prolong the contact with the host, and therefore favour its persistence in the gut. In the present study, the contribution of plasmid-encoded factors to the adhesive and transit properties of the L. lactis subsp. cremoris IBB477 strain was investigated. Plasmid-cured derivatives as well as deletion mutants were obtained and analysed. Adhesion tests were performed using non-coated polystyrene plates, plates coated with mucin or fibronectin and mucus-secreting HT29-MTX intestinal epithelial cells. The results indicate that two plasmids, pIBB477a and b, are involved in adhesion of the IBB477 strain. One of the genes localised on plasmid pIBB477b (AJ89_14230), which encodes cell wall-associated peptidase S8 (PrtP), mediates adhesion of the IBB477 strain to bare, mucin- and fibronectincoated polystyrene, as well as to HT29-MTX cells. Interactions between bacteria and mucus secreted by HT29- MTX cells were further investigated by fluorescent staining and confocal microscopy. Confocal images showed that IBB477 forms dense clusters embedded in secreted mucus. Finally, the ability of IBB477 strain and its ΔprtP deletion mutant to colonise the gastrointestinal tract of conventional C57Bl/6mice was determined. Both strains were present in the gut for up to 72 h. In summary, adhesion and persistence of IBB477 were analysed by in vitro and in vivo approaches, respectively. Our studies revealed that plasmidic genes encoding cell surface proteins are more involved in the adhesion of IBB477 strain than in the ability to confer a selective advantage in the gut

Abyssal fauna of the UK-1 polymetallic nodule exploration area, Clarion-Clipperton Zone, central Pacific Ocean: Mollusca

The file attached is the Published/publisher’s pdf version of the article. This is an OpenAccess article.Copyright Helena Wiklund et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited