2,350 research outputs found

    Electricity consumption forecasting using Adaptive Neuro-Fuzzy Inference System (ANFIS)

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    Universiti Tun Hussein Onn Malaysia (UTHM) is a developing Malaysian Technical University. There is a great development of UTHM since its formation in 1993. Therefore, it is crucial to have accurate future electricity consumption forecasting for its future energy management and saving. Even though there are previous works of electricity consumption forecasting using Adaptive Neuro-Fuzzy Inference System (ANFIS), but most of their data are multivariate data. In this study, we have only univariate data of UTHM electricity consumption from January 2009 to December 2018 and wish to forecast 2019 consumption. The univariate data was converted to multivariate and ANFIS was chosen as it carries both advantages of Artificial Neural Network (ANN) and Fuzzy Inference System (FIS). ANFIS yields the MAPE between actual and predicted electricity consumption of 0.4002% which is relatively low if compared to previous works of UTHM electricity forecasting using time series model (11.14%), and first-order fuzzy time series (5.74%), and multiple linear regression (10.62%)

    Large Area Roller Embossing of Multilayered Ceramic Green Composites

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    In this paper, we will report our achievements in developing large area patterning of multilayered ceramic green composites using roller embossing. The aim of our research is to pattern large area ceramic green composites using a modified roller laminating apparatus, which is compatible with screen printing machines, for integration of embossing and screen printing. The instrumentation of our roller embossing apparatus, as shown in Figure1, consists of roller 1 and rollers 2. Roller 1 is heated up to the desired embossing temperature ; roller 2 is, however, kept at room temperature. The mould is a nickel template manufactured by plating nickel-based micro patterns (height : 50 μ\mum) on a nickel film (thickness : 70 μ\mum) ; the substrate for the roller embossing is a multilayered Heraeus Heralock HL 2000 ceramic green composite. Comparing with the conventional simultaneous embossing, the advantages of roller embossing include : (1) low embossing force ; (2) easiness of demoulding ; (3) localized area in contact with heater ; and etc. We have demonstrated the capability of large area roller embossing with a panel size of 150mmx 150mm on the mentioned substrate. We have explored and confirmed the impact of parameters (feed speed, temperature of roller and applied pressure) to the pattern quality of roller embossing. Furthermore, under the optimized process parameters, we characterized the variations of pattern dimension over the panel area, and calculated a scaling factor in order to make the panel compatible with other processes. Figure 2 shows the embossed patterns on a 150mmx 150mm green ceramic panel.Comment: Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/handle/2042/16838

    The expanding phenotype of MELAS caused by the m.3291T \u3e C mutation in the MT-TL1 gene

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    Crown Copyright © 2016 Published by Elsevier Inc. m.3291T \u3e C mutation in the MT-TL1 gene has been infrequently encountered in association with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS), however remains poorly characterized from a clinical perspective. In the following report we describe in detail the phenotypic features, long term follow up (\u3e 7 years) and management in a Caucasian family with MELAS due to the m.3291T \u3e C mutation and review the literature on m.3291T \u3e C mutation. The clinical phenotype in the proposita included overlapping features of MELAS, MERRF (Myoclonic epilepsy and ragged-red fiber syndrome), MNGIE (Mitochondrial neurogastrointestinal encephalopathy), KSS (Kearns-Sayre Syndrome) and CPEO (Chronic progressive external ophthalmoplegia)

    Bonding of self-etch and total-etch adhesives to carious dentin

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    Case of Multiple Sulfatase Deficiency and Ocular Albinism: A Diagnostic Odyssey

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    Background: Multiple sulfatase deficiency (MSD) is a rare autosomal recessive inborn error of lysosomal metabolism. The clinical phenotypic spectrum encompasses overlapping features of variable severity and is suggestive of individual single sulfatase deficiencies (i.e., metachromatic leukodystrophy, mucopolysaccharidosis, and X-linked ichthyosis). Case Report: We describe a 3-year-old male with severe hypotonia, developmental regression and progressive neurodegeneration, coarse facial features, nystagmus (from ocular albinism), and dysmyelinating motor sensory neuropathy. Ethics approval was obtained from the Western University Ontario. Results: Extensive investigative work-up identified deficiencies of multiple sulfatases: heparan sulfate sulfamidase: 6.5 nmoles/mg/protein/17 hour (reference 25.0-75.0), iduronate-2-sulfate sulfatase: 9 nmol/mg/protein/4 hour (reference 31-110), and arylsulfatase A: 3.8 nmoles/hr/mg protein (reference 22-50). The identification of compound heterozygous pathogenic mutations in the SUMF1 gene c.836 C\u3eT (p.A279V) and c.1045C\u3eT (p.R349W) confirmed the diagnosis of MSD. Conclusion: The complex clinical manifestations of MSD and the unrelated coexistence of ocular albinism as in our case can delay diagnosis. Genetic counselling should be provided to all affected families

    MELAS: A multigenerational impact of the MTTL1 A3243G MELAS mutation

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    Background: the maternally inherited MTTL1 A3243G mutation in the mitochondrial genome causes MelaS (Mitochondrial encephalopathy lactic acidosis with Stroke-like episodes), a condition that is multisystemic but affects primarily the nervous system. Significant intra-familial variation in phenotype and severity of disease is well recognized. Methods: retrospective and ongoing study of an extended family carrying the MTTL1 A3243G mutation with multiple symptomatic individuals. tissue heteroplasmy is reviewed based on the clinical presentations, imaging studies, laboratory findings in affected individuals and pathological material obtained at autopsy in two of the family members. Results: there were seven affected individuals out of thirteen members in this three generation family who each carried the MTTL1 A3243G mutation. the clinical presentations were varied with symptoms ranging from hearing loss, migraines, dementia, seizures, diabetes, visual manifestations, and stroke like episodes. three of the family members are deceased from MelaS or to complications related to MelaS. Conclusions: the results of the clinical, pathological and radiological findings in this family provide strong support to the current concepts of maternal inheritance, tissue heteroplasmy and molecular pathogenesis in MelaS. neurologists (both adult and paediatric) are the most likely to encounter patients with MelaS in their practice. genetic counselling is complex in view of maternal inheritance and heteroplasmy. newer therapeutic options such as arginine are being used for acute and preventative management of stroke like episodes. © 2014 Canadian Journal of neurologiCal sciences inc

    Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease

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    We present the first application of the hypothesis-rich mathematical theory to genome-wide association data. The Hamza et al. late-onset sporadic Parkinson's disease genome-wide association study dataset was analyzed. We found a rare, coding, non-synonymous SNP variant in the gene DZIP1 that confers increased susceptibility to Parkinson's disease. The association of DZIP1 with Parkinson's disease is consistent with a Parkinson's disease stem-cell ageing theory.Comment: 14 page

    Structural and doping effects in the half-metallic double perovskite A2A_2CrWO6_6

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    he structural, transport, magnetic and optical properties of the double perovskite A2A_2CrWO6_6 with A=Sr, Ba, CaA=\text{Sr, Ba, Ca} have been studied. By varying the alkaline earth ion on the AA site, the influence of steric effects on the Curie temperature TCT_C and the saturation magnetization has been determined. A maximum TC=458T_C=458 K was found for Sr2_2CrWO6_6 having an almost undistorted perovskite structure with a tolerance factor f1f\simeq 1. For Ca2_2CrWO6_6 and Ba2_2CrWO6_6 structural changes result in a strong reduction of TCT_C. Our study strongly suggests that for the double perovskites in general an optimum TCT_C is achieved only for f1f \simeq 1, that is, for an undistorted perovskite structure. Electron doping in Sr2_2CrWO6_6 by a partial substitution of Sr2+^{2+} by La3+^{3+} was found to reduce both TCT_C and the saturation magnetization MsM_s. The reduction of MsM_s could be attributed both to band structure effects and the Cr/W antisites induced by doping. Band structure calculations for Sr2_2CrWO6_6 predict an energy gap in the spin-up band, but a finite density of states for the spin-down band. The predictions of the band structure calculation are consistent with our optical measurements. Our experimental results support the presence of a kinetic energy driven mechanism in A2A_2CrWO6_6, where ferromagnetism is stabilized by a hybridization of states of the nonmagnetic W-site positioned in between the high spin Cr-sites.Comment: 14 pages, 10 figure

    Quantum Magnetization Plateau in Spin-1 Triangular-Lattice Antiferromagnet Ba3_3NiSb2_2O9_9

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    We report the results of magnetization and specific heat measurements on Ba3_3NiSb2_2O9_9, which is a quasi-two-dimensional spin-1 triangular-lattice antiferromagnet. We observed a nonclassical magnetization plateau at one-third of the saturation magnetization that is driven by spin frustration and quantum fluctuation. Exact diagonalization for a 21-site rhombic cluster was performed to analyze the magnetization process. Experimental and calculated results agree well.Comment: published in Journal of the Physical Society of Japan 80 (2011) 09370
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