Self-sustained oscillations in homogeneous shear flow

Generation of the large-scale coherent vortical structurs in homogeneous shear flow couples dynamical processes of energy and enstrophy production. In the large rate of strain limit, the simple estimates of the contributions to the energy and enstrophy equations result in a dynamical system, describing experimentally and numerically observed self-sustained non-linear oscillations of energy and enstrophy. It is shown that the period of these oscilaltions is independent upon the box size and the energy and enstrophy fluctuations are strongly correlated.Comment: 10 pages 6 figure

Landslide susceptibility mapping using the Rock Engineering System approach and GIS technique: an example from southwest Arcadia (Greece)

The purpose of this study is to prepare a susceptibility map in a landslide-prone area in Greece using Rock Engineering System (RES) and a geoprocessing tool called Model Builder. The implementation of RES is achieved through an interaction matrix, where ten parameters were selected as controlling factors for the landslide occurence. The validation of the developed model was achieved by using field-verified data, showing excellent correlation between the expected and existing landslide susceptibility level. In conjunction with Model Builder, which can overlay different layers and produce landslide susceptibility maps, RES can act as a tool for calculating the instability index and getting a prognosis of a potential slope failure in relation to sustainable development planning processes in landslide susceptible areas

Heat transfer from a flat plate in inhomogeneous regions of grid-generated turbulence

Experiments on the convective heat transfer from a flat plate, vertically mounted and parallel to the flow in a wind tunnel, were carried out via Infra-Red thermography and hot-wire anemometry. The Reynolds number based on the inflow velocity and on the length of the plate was about 5×1055×105. A step near the leading edge of the plate was used to promote transition to turbulence, with tripping effects on the heat transfer coefficients shown to be negligible for more than 90% of the plate’s length. Different types of grids, all with same blockage ratio σg=28%σg=28%, were placed upstream of the plate to investigate their potential to enhance the turbulent heat transfer. These grids were of three classes: regular square-mesh grids (RGs), single-square grids (SSGs) and multi-scale inhomogeneous grids (MIGs). The heat transfer coefficients at the mid-length of the plate were correlated with the mean velocity and the turbulence intensity of the flow at a distance from the plate at which the ratio of the standard deviations of the streamwise and wall-normal velocity fluctuations began to increase. However, the heat transfer was shown to be insensitive to the turbulence intensity of the incoming flow in close proximity of the tripping step. Furthermore, the integral length scale of the streamwise turbulent fluctuations was found not to affect the heat transfer results, both near the tripping step and in the well-developed region on the plate. For the smallest plate-to-grid distance, the strongest heat transfer enhancement (by roughly 30%) with respect to the no-grid case was achieved with one of the SSGs. For the largest plate-to-grid distance, the only grid producing an appreciable increase (by approximately 10%) of the heat transfer was one of the MIGs. The present results demonstrate that MIG design can be optimised to maximise the overall heat transfer from the plate. A MIG that produces a uniform transverse mean shear, which is approximately preserved over significant downstream distances from the grid and with a velocity decreasing with distance from the plate, allows a sustained heat transfer enhancement, in contrast to all other grid designs tested here. The most efficient configuration for a MIG is one for which the section of the grid that has lower blockage and thicker bars is adjacent to the plate

Mutational analysis of the major proline transporter (PrnB) of Aspergillus nidulans

PrnB, the L-proline transporter of Aspergillus nidulans, belongs to the Amino acid Polyamine Organocation (APC) transporter family conserved in prokaryotes and eukaryotes. In silico analysis and limited biochemical evidence suggest that APC transporters comprise 12 transmembrane segments (TMS) connected with relatively short hydrophilic loops (L). However, very little is known on the structure-function relationships in APC transporters. This work makes use of the A. nidulans PrnB transporter to address structure-function relationships by selecting, constructing and analysing several prnB mutations. In the sample, most isolated missense mutations affecting PrnB function map in the borders of cytoplasmic loops with transmembrane domains. These are I119N and G120W in L2-TMS3, F278V in L6-TMS7, NRT378NRTNRT and PY382PYPY in L8-TMS9 and T456N in L10-TMS11. A single mutation (G403E) causing, however, a very weak phenotype, maps in the borders of an extracellular loop (L9-TMS10). An important role of helix TMS6 for proline binding and transport is supported by mutations K245L and, especially, F248L that clearly affect PrnB uptake kinetics. The critical role of these residues in proline binding and transport is further shown by constructing and analysing isogenic strains expressing selected prnB alleles fused to the gene encoding the Green Fluorescent Protein (GFP). It is shown that, while some prnB mutations affect proper translocation of PrnB in the membrane, at least two mutants, K245E and F248L, exhibit physiological cellular expression of PrnB and, thus, the corresponding mutations can be classified as mutations directly affecting proline binding and/or transport. Finally, comparison of these results with analogous studies strengthens conclusions concerning amino acid residues critical for function in APC transporters

16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands.

In the last fifteen years, published reports have described KIR gene-content frequency distributions in more than 120 populations worldwide. However, there have been limited studies examining these data in aggregate to detect overall patterns of variation at regional and global levels. Here, we present a summary of the collection of KIR gene-content data for 105 worldwide populations collected as part of the 15th and 16th International Histocompatibility and Immunogenetics Workshops, and preliminary results for data analysis

Statistical Properties of Turbulence: An Overview

We present an introductory overview of several challenging problems in the statistical characterisation of turbulence. We provide examples from fluid turbulence in three and two dimensions, from the turbulent advection of passive scalars, turbulence in the one-dimensional Burgers equation, and fluid turbulence in the presence of polymer additives.Comment: 34 pages, 31 figure

Numerical simulation of turbulent flow in a channel containing a small slot

A three-dimensional unsteady simulation was carried out to predict the main features of the turbulent flow inside a closed channel connected to a lateral slot. The incompressible turbulent flow was modelled using a hybrid Detached Eddy Simulation (DES), that uses an LES/URANS approach to predict the turbulence. The calculations were performed using ANSYS® CFX. In this work the main channel has a size of 180 mm x 136.20 mm. The small subchannel is characterized by its deepness, p = 77 mm and width, d = 10 mm. The Reynolds number, based on the hydraulic-diameter, Dh, the bulk velocity, and the kinematic viscosity, ν, in the main channel was Re = 2.25 × 105. Inside the small slot the velocity distribution was found to depart from the law of the wall and the normal Reynolds stresses, View the MathML sourceu′u′¯ and View the MathML sourcev′v′¯, were found to dominate the mixing process. Velocity time-traces extracted at locations as far as y/p = 1.125 inside the gap evidenced the presence of large eddies travelling inside the small channel. It was shown that periodic streamwise boundary conditions can be applied to this problem, and good results were obtained by using a channel length that was approximately twice the wavelength of the experimentally observed coherent structures. The results were found to be in fair agreement with the results presented in Meyer and Rehme (1994), though a certain lack of information on turbulence in single channels connected to a gap still remains