Tromboembolismo como fator associado ao uso de anticoncepcional hormonal.

INTRODUCTION: Hormonal contraceptive methods are constantly used nowadays, with a view to contraception. In developed countries such as the United States, there is a range of around 18% of use of different methods among women. In developing countries like Brazil, this percentage reaches up to 75%. OBJECTIVE: To present, according to scientific literature, the main factors associated with the use of contraceptives in the development of thromboembolism. METHODOLOGY: This is a qualitative study, it refers to an integrative review of the literature, presenting a synthesis of the studies analyzed in full, organizing them for the elaboration of results regarding the established theme, being carried out in the month of September 2023. RESULTS: The development  of  Thromboembolism  caused  by  the  various oral  contraceptive methods  is  evidenced  through  studies that  demonstrate  the  serious  risks  to  female  health, requiring  greater caution  in the use  of  hormonal  and emergency  pills. FINAL CONSIDERATIONS: Therefore, it is noted that the use of hormonal contraceptives brings benefits such as preventing conception, however it can be a major factor in the development of thromboembolism.INTRODUÇÃO: Os métodos contraceptivos hormonais são utilizados constantemente nos dias atuais, tendo em vista a anticoncepção. Em países desenvolvidos como Estados Unidos existe um alcance de cerca 18% da utilização dos diversos métodos entre as mulheres. Já em países em desenvolvimento como o Brasil, esse percentual chega a até  75%. OBJETIVO: Apresentar, de acordo com a literatura científica,  os principais fatores associados ao uso de anticoncepcionais no desenvolvimento de tromboembolismo. METODOLOGIA: Trata-se de um estudo qualitativo, refere-se a uma revisão integrativa da literatura, apresentando uma síntese dos estudos analisados na íntegra, organizando-os para a elaboração dos resultados a respeito da temática estabelecida, sendo realizada no mês de setembro de 2023. RESULTADOS: O desenvolvimento  do  Tromboembolismo  ocasionado  pelos  diversos métodos contraceptivos  orais  é  evidenciado  por meio  de  estudos que  demonstram  os  graves  riscos  para a  saúde  feminina, necessitando  de uma  maior cautela  no uso  da  pílula  hormonal e na de emergência. CONSIDERAÇÕES FINAIS: Portanto, nota-se que o uso do anticoncepcional hormonal traz benefícios como evitar a concepção, todavia pode ser um grande fator para o desenvolvimento do tromboembolismo

Factors associated with smoking cessation

OBJECTIVE To analyze the prevalence and factors associated with smoking abstinence among patients who were treated in a reference unit for smoking cessation.METHODS This cross-sectional study examined the medical records of 532 patients treated in a reference unit for smoking cessation in Belém, PA, Northern Brazil, between January 2010 and June 2012. Sociodemographic variables and those related to smoking history and treatment were analyzed. Statistical significance was set at p < 0.05.RESULTS The mean age of the participants was 50 years; 57.0% of the patients were women. The mean tobacco load was 30 packs/year, and the mean smoking duration was approximately 32 years. Most patients remained in treatment for four months. The rate of smoking abstinence was 75.0%. Regression analysis indicated that maintenance therapy, absence of relapse triggers, and lower chemical dependence were significantly associated with smoking cessation.CONCLUSIONS The smoking abstinence rate observed was 75.0%. The cessation process was associated with several aspects, including the degree of chemical dependence, symptoms of withdrawal, and period of patient follow-up in a multidisciplinary treatment program. Studies of this nature contribute to the collection of consistent epidemiological data and are essential for the implementation of effective smoking prevention and cessation strategies

High prevalence of dengue antibodies and the arginine variant of the Fc?RIIa polymorphism in asymptomatic individuals in a population of Minas Gerais State, Southeast Brazil.

Dengue is the most prevalent arthropod-borne viral illness in humans worldwide. Single-nucleotide polymorphisms (SNPs) in genes involved in the immune response, such as dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), IgG Fc receptor II-A (Fc?RIIa), vitamin D receptor (VDR), and tumor necrosis factor alpha (TNF-?), were previously reported to be associated with susceptibility to dengue disease in different human populations. Therefore, due to the relevant association of host immune and genetic status with disease susceptibility/severity of dengue, this work aims to verify the frequency of anti-dengue virus antibodies and some dengue-associated risk SNPs in a population in Minas Gerais State, Southeast Brazil. A total of 1560 individuals were genotyped for polymorphisms in DC-SIGN (rs4804803), Fc?RIIa (rs1801274), VDR (rs7975232), and TNF-? (rs1800629). The presence of anti-dengue antibodies (IgM and/or IgG) in these samples was also assayed. Anti-dengue antibodies were detected at an overall frequency of 16.86%, indicating a virus infection in asymptomatic individuals. The genotypic frequencies of all SNPs studied did not differ between the asymptomatic and control groups. Regarding the allelic frequencies of the four SNPs analyzed, a higher frequency was detected of the G allele of Fc?RIIa/rs1801274 in the asymptomatic individuals when compared to that in the control group (p =0.03). Therefore, the results showed a high prevalence of asymptomatic individuals in Minas Gerais State, with a potential association between the presence of the G allele of Fc?RIIa/rs1801274 and protection against symptomatic disease

Resumos em andamento - Saúde Coletiva

Resumos em andamento - Saúde Coletiv

Resumos em andamento - Saúde Coletiva

Resumos em andamento - Saúde Coletiv

Núcleos de Ensino da Unesp: artigos 2008

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Resumos concluídos - Saúde Coletiva

Resumos concluídos - Saúde Coletiv

NEOTROPICAL XENARTHRANS: a data set of occurrence of xenarthran species in the Neotropics

Xenarthrans—anteaters, sloths, and armadillos—have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, 10 anteaters, and 6 sloths. Our data set includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the southern United States, Mexico, and Caribbean countries at the northern portion of the Neotropics, to the austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n = 5,941), and Cyclopes sp. have the fewest (n = 240). The armadillo species with the most data is Dasypus novemcinctus (n = 11,588), and the fewest data are recorded for Calyptophractus retusus (n = 33). With regard to sloth species, Bradypus variegatus has the most records (n = 962), and Bradypus pygmaeus has the fewest (n = 12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other data sets of Neotropical Series that will become available very soon (i.e., Neotropical Carnivores, Neotropical Invasive Mammals, and Neotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure, habitat loss, fragmentation effects, species invasion, and climate change effects will be possible with the Neotropical Xenarthrans data set. Please cite this data paper when using its data in publications. We also request that researchers and teachers inform us of how they are using these data