Estimation of Grain Size Distribution of Friction Stir Welded Joint by using Machine Learning Approach

Machine learning has widely spread in the areas of pattern recognition, prediction or forecasting, cognitive game theory and in bioinformatics. In recent days, machine learning is being introduced into manufacturing and material industries for the development of new materials and simulating the manufacturing of the required products. In the recent paper, machine learning algorithm is developed by using Python programming for the determination of grain size distribution in the microstructure of stir zone seam of Friction Stir Welded magnesium AZ31B alloy plate The grain size parameters such as an equivalent diameter, perimeter, area, orientation etc. were determined. The results showed that the developed algorithm is able to determine various grain size parameters accurately

Toward multifunctional materials incorporating stepladder manganese(III) inverse-[9-MC-3]-Metallacrowns and anti-inflammatory drugs

The interaction of Mn(ClO4)2·6H2O with salicylaldoxime (H2sao) in the presence of nonsteroidal anti-inflammatory drug (NSAID) sodium diclofenac (Nadicl) or indomethacin (Hindo) leads to the formation of the hexanuclear Mn(III) clusters [Mn6(O)2(dicl)2(sao)6(CH3OH)6] (1) and [Mn6(O)2(indo)2(sao)6(H2O)4] (2) both characterized as stepladder inverse-9-metallacrown-3 accommodating dicl- or indo- ligands, respectively. When the interaction of MnCl2·4H2O with Nadicl or Hindo is in the absence of H2sao, the mononuclear Mn(II) complexes [Mn(dicl)2(CH3OH)4] (3) and [Mn(indo)2(CH3OH)4] (4) were isolated. The complexes were characterized by physicochemical and spectroscopic techniques, and the structure of complexes 1 and 2 was characterized by X-ray crystallography. Magnetic measurements (dc and ac) were carried out in order to investigate the nature of magnetic interactions between the magnetic ions and the overall magnetic behavior of the complexes

Structure and biological activities of metal complexes of flumequine

The reaction of CoCl2·6H2O with the quinolone antimicrobial agent flumequine (Hflmq) in the absence or presence of the α-diimines 2,2′-bipyridine (bipy), 1,10-phenanthroline (phen) or 2,2′-bipyridylamine (bipyam) resulted in the formation of four mononuclear complexes which were characterized with physicochemical and spectroscopic techniques. The crystal structures of [Co(flmq)2(bipy)]·2H2O, [Co(flmq)2(phen)]·1.6MeOH·0.4H2O and [Co(flmq)2(bipyam)]·H2O were determined by X-ray crystallography. The interaction of the complexes with calf-thymus DNA (CT DNA) was investigated by UV spectroscopy, viscosity measurements, cyclic voltammetry and competitive studies with ethidium bromide in order to evaluate the possible DNA-binding mode and to calculate the corresponding DNA-binding constants. The binding of the complexes to human or bovine serum albumin was studied by fluorescence emission spectroscopy and the corresponding binding constants were determined. The antimicrobial activity of the Co(II)–flumequine and the recently reported Cu(II)–flumequine complexes was tested against four different microorganisms (Escherichia coli, Xanthomonas campestris, Staphylococcus aureus and Bacillus subtilis) and was found to be similar to that of free Hflmq. The antiproliferative activity of previously reported complexes [Cu(flmq)(phen)Cl], [Zn(flmq)(phen)Cl] and [Ni(flmq)2(phen)] against human ovarian (A2780) and lung (A549) cancer cell lines is also reported in comparison to the cobalt analogue, [Co(flmq)(phen)Cl], 3, highlighting important differences among the various complexes which may be due to different uptake and modes of action

Topological insights in polynuclear Ni/Na coordination clusters derived from a schiff base ligand

This article presents the syntheses, crystal structures, topological features and magnetic properties of two NiII/NaI coordination clusters (CCs) formulated [NiII3Na(L1)3(HL1 (MeOH)2] (1) and [NiII6Na(L1)5(CO3)(MeO (MeOH)3(H2O)3]·4(MeOH) 2(H2O) [2 4(MeOH) 2(H2O)] where H2L1 is the semi rigid Schiff base ligand (E)-2-(2-hydroxy-3 methoxybenzylideneamino)-phenol). Compound 1 possesses a rare NiII3NaI cubane (3M4-1) topology and compound 2 is the first example in polynuclear Ni/Na chemistry that exhibits a 2,3,4M7-1 topology

How India’s tilted foreign policy paved China’s road to South Asia

This post by Tarushi Aswani examines India’s relationship with fellow South Asian countries, and how recent foreign policy initiatives may have rendered the largest democracy in the world ‘friendless’ in its South Asian neighbourhood, paving the way further for China to make inroads into South Asia

New copper(II) complexes of the anti-inflammatory drug mefenamic acid: A concerted study including synthesis, physicochemical characterization and their biological evaluation

Reaction of hydrated copper(ii) mefenamate in the presence of diverse N-donor ligands such as N,N,N′,N′-tetramethylethylenediamine (temed), ethylenediamine (en), β-picoline (β-pic) in a methanol:water mixture (4:1, v/v) yielded crystalline monomeric copper(ii) complexes [Cu(temed) (mefenamato)2], 1, [Cu(en)2(H2O)2](mefenamato)2, 2 and [Cu(β-pic)2(mefenamato)2]·H2O, 3. The newly synthesized complexes have been characterized by elemental analysis, spectroscopic methods (FT-IR, UV-Vis and EPR), thermogravimetric analyses and single-crystal X-ray structure determination in the case of complexes 2 and 3. The ground-state geometry optimization of complex 1 was performed by DFT calculations. In order to verify the complexes capability to get bound and possibly transported by the albumin towards their biological targets (cells and/or tissues), the interaction with bovine (BSA) and human serum albumin (HSA) was studied by fluorescence emission spectroscopy. The interaction of complexes 1-3 with calf-thymus DNA (CT DNA) was monitored by UV-Vis spectroscopy, cyclic voltammetry, viscosity measurements and via the ethidium bromide (EB) displacement from the EB-DNA conjugate performed by fluorescence emission spectroscopy, as a preliminary approach to evaluate their potential biological activity