812 research outputs found
Rossby wave instability in locally isothermal and polytropic disks: three-dimensional linear calculations
Numerical calculations of the linear Rossby wave instability (RWI) in global
three-dimensional (3D) disks are presented. The linearized fluid equations are
solved for vertically stratified, radially structured disks with either a
locally isothermal or polytropic equation of state, by decomposing the vertical
dependence of the perturbed hydrodynamic quantities into Hermite and Gegenbauer
polynomials, respectively. It is confirmed that the RWI operates in 3D. For
perturbations with vertical dependence assumed above, there is little
difference in growth rates between 3D and two-dimensional (2D) calculations.
Comparison between 2D and 3D solutions of this type suggest the RWI is
predominantly a 2D instability and that three-dimensional effects, such as
vertical motion, to be interpreted as a perturbative consequence of the
dominant 2D flow. The vertical flow around co-rotation, where vortex-formation
is expected, is examined. In locally isothermal disks the expected vortex
center remains in approximate vertical hydrostatic equilibrium. For polytropic
disks the vortex center has positive vertical velocity, whose magnitude
increases with decreasing polytropic index .Comment: 17 pages, 21 figures, Accepted by Ap
Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid‐beta peptide levels in vivo
J Lipid Res. 2007 Apr;48(4):914-23. Epub 2007 Jan 18.
Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-beta peptide levels in vivo.
Hirsch-Reinshagen V, Chan JY, Wilkinson A, Tanaka T, Fan J, Ou G, Maia LF, Singaraja RR, Hayden MR, Wellington CL.
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Abstract
ABCA1-deficient mice have low levels of poorly lipidated apolipoprotein E (apoE) and exhibit increased amyloid load. To test whether excess ABCA1 protects from amyloid deposition, we crossed APP/PS1 mice to ABCA1 bacterial artificial chromosome (BAC) transgenic mice. Compared with wild-type animals, the ABCA1 BAC led to a 50% increase in cortical ABCA1 protein and a 15% increase in apoE abundance, demonstrating that this BAC supports modest ABCA1 overexpression in brain. However, this was observed only in animals that do not deposit amyloid. Comparison of ABCA1/APP/PS1 mice with APP/PS1 controls revealed no differences in levels of brain ABCA1 protein, amyloid, Abeta, or apoE, despite clear retention of ABCA1 overexpression in the livers of these animals. To further investigate ABCA1 expression in the amyloid-containing brain, we then compared ABCA1 mRNA and protein levels in young and aged cortex and cerebellum of APP/PS1 and ABCA1/APP/PS1 animals. Compared with APP/PS1 controls, aged ABCA1/APP/PS1 mice exhibited increased ABCA1 mRNA, but not protein, selectively in cortex. Additionally, ABCA1 mRNA levels were not increased before amyloid deposition but were induced only in the presence of extensive Abeta and amyloid levels. These data suggest that an induction of ABCA1 expression may be associated with late-stage Alzheimer's neuropathology.
PMID: 17235115 [PubMed - indexed for MEDLINE
Type III migration in a low viscosity disc
We study the type III migration of a Saturn mass planet in low viscosity
discs. The planet is found to experience cyclic episodes of rapid decay in
orbital radius, each amounting to a few Hill radii. We find this to be due to
the scattering of large- scale vortices present in the disc. The origin and
role of vortices in the context of type III migration is explored. It is shown
through numerical simulations and semi- analytical modelling that spiral shocks
induced by a sufficiently massive planet will extend close to the planet
orbital radius. The production of vortensity across shock tips results in thin
high vortensity rings with a characteristic width of the local scale height.
For planets with masses equal to and above that of Saturn, the rings are
co-orbital features extending the entire azimuth. Linear stability analysis
show there exists unstable modes that are localised about local vortensity
minima which coincide with gap edges. Simulations show that vortices are
non-linear a outcome. We used hydrodynamic simulations to examine vortex-planet
interactions. Their effect is present in discs with kinematic viscosity less
than about an order of magnitude smaller than the typically adopted value of
\nu = 10^{-5}\Omega_pr_p(0)^2, where r_p(0) and \Omega_p are the initial
orbital radius and angular velocity of the planet respectively. We find that
the magnitude of viscosity affects the nature of type III migration but not the
extent of the orbital decay. The role of vortices as a function of initial disc
mass is also explored and it is found that the amount of orbital decay during
one episode of vortex-planet interaction is independent of initial disc mass.
We incorporate the concept of the co-orbital mass deficit in the analysis of
our results and link it to the presence of vortices at gap edges.Comment: 20 pages, 20 figures, accepted for publication in MNRA
文書領域情報を有するBERTの階層位置に関する考察
Ibaraki UniversityIbaraki UniversityIbaraki UniversityIbaraki UniversityIbaraki UniversityIbaraki University会議名: 言語資源活用ワークショップ2019, 開催地: 国立国語研究所, 会期: 2019年9月2日−4日, 主催: 国立国語研究所 コーパス開発センターBERTはTransformerで利用されるMulti-head attentionを12層(あるいは24層)積み重ねたモデルである。各層のMulti-head attentionは、基本的に、入力単語列に対応する単語埋め込み表現列を出力している。BERTの各層では低層から徐々に何からの情報を取り出しながら、その文脈に応じた単語の埋め込み表現を構築していると考えられる。本論文では領域適応で問題となる領域情報に注目し、BERTの出力の各層が持つ領域情報がどのように推移するのかを考察する
A generalized quantum nonlinear oscillator
We examine various generalizations, e.g. exactly solvable, quasi-exactly
solvable and non-Hermitian variants, of a quantum nonlinear oscillator. For all
these cases, the same mass function has been used and it has also been shown
that the new exactly solvable potentials possess shape invariance symmetry. The
solutions are obtained in terms of classical orthogonal polynomials
Information Geometry of Quantum Entangled Gaussian Wave-Packets
Describing and understanding the essence of quantum entanglement and its
connection to dynamical chaos is of great scientific interest. In this work,
using information geometric (IG) techniques, we investigate the effects of
micro-correlations on the evolution of maximal probability paths on statistical
manifolds induced by systems whose microscopic degrees of freedom are Gaussian
distributed. We use the statistical manifolds associated with correlated and
non-correlated Gaussians to model the scattering induced quantum entanglement
of two spinless, structureless, non-relativistic particles, the latter
represented by minimum uncertainty Gaussian wave-packets. Knowing that the
degree of entanglement is quantified by the purity P of the system, we express
the purity for s-wave scattering in terms of the micro-correlation coefficient
r - a quantity that parameterizes the correlated microscopic degrees of freedom
of the system; thus establishing a connection between entanglement and
micro-correlations. Moreover, the correlation coefficient r is readily
expressed in terms of physical quantities involved in the scattering, the
precise form of which is obtained via our IG approach. It is found that the
entanglement duration can be controlled by the initial momentum p_{o}, momentum
spread {\sigma}_{o} and r. Furthermore, we obtain exact expressions for the IG
analogue of standard indicators of chaos such as the sectional curvatures,
Jacobi field intensities and the Lyapunov exponents. We then present an
analytical estimate of the information geometric entropy (IGE); a suitable
measure that quantifies the complexity of geodesic paths on curved manifolds.
Finally, we present concluding remarks addressing the usefulness of an IG
characterization of both entanglement and complexity in quantum physics.Comment: 37 pages, 3 figure
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