4,252 research outputs found
Electron beam compression with electric and magnetic fields
Electron beam compression with electrostatic and magnetostatic field
The medical student
The Medical Student was published from 1888-1921 by the students of Boston University School of Medicine
A preliminary evaluation of a new control-knob design for electronic equipment
Two experiments were carried out using five subjects to compare
performance using standard and flush fitting rotary controls for electronic
equipment. It vas found that the flush knob could be rotated more quickly
through several revolutions, but a given setting accuracy was achieved less
quickly using this flush knob.
Some of the more general advantages and disadvantages of the flush
knob are outlined.
It should be noted that the primary objective of this study was to
provide the participants with some experience in carrying out Human Factors
studies and the time allowed was not such as to permit a comprehensive
evaluation of the new knob design
PT-Symmetric Talbot Effects
We show that complex PT-symmetric photonic lattices can lead to a new class
of self-imaging Talbot effects. For this to occur, we find that the input field
pattern, has to respect specific periodicities which are dictated by the
symmetries of the system. While at the spontaneous PT-symmetry breaking point,
the image revivals occur at Talbot lengths governed by the characteristics of
the passive lattice, at the exact phase it depends on the gain and loss
parameter thus allowing one to control the imaging process.Comment: 5 pages, 3 figure
Simulation study of random sequential adsorption of mixtures on a triangular lattice
Random sequential adsorption of binary mixtures of extended objects on a
two-dimensional triangular lattice is studied numerically by means of Monte
Carlo simulations. The depositing objects are formed by self-avoiding random
walks on the lattice. We concentrate here on the influence of the symmetry
properties of the shapes on the kinetics of the deposition processes in
two-component mixtures. Approach to the jamming limit in the case of mixtures
is found to be exponential, of the form: and the values of the parameter
are determined by the order of symmetry of the less symmetric object
in the mixture. Depending on the local geometry of the objects making the
mixture, jamming coverage of a mixture can be either greater than both
single-component jamming coverages or it can be in between these values.
Results of the simulations for various fractional concentrations of the objects
in the mixture are also presented.Comment: 11 figures, 2 table
Global perspective of nitrate flux in ice cores
The relationships between the concentration and the flux of chemical species (Cl-, NO3 - , SO42-, Na +, K + , NH4 + , Mg 2+ , Ca 2+) versus snow accumulation rate were examined at GISP2 and 20D in Greenland, Mount Logan from the St. Elias Range, Yukon Territory, Canada, and Sentik Glacier from the northwest end of the Zanskar Range in the Indian Himalayas. At all sites, only nitrate flux is significantly (a = 0.05) related to snow accumulation rate. Of all the chemical series, only nitrate concentration data are normally distributed. Therefore we suggest that nitrate concentration in snow is affected by postdepositionaJ exchange with the atmosphere over a broad range of environmental conditions. The persistent summer maxima in nitrate observed in Greenland snow over the entire range of record studied (the last 800 years) may be mainly due to NO• released from peroxyacetyl nitrate by thermal decomposition in the presence of higher OH concentrations in summer. The late winter/early spring nitrate peak observed in modern Greenland snow may be related to the buildup of anthropogenically derived N Oy in the Arctic troposphere during the long polar winter
Laminin and fibronectin in rectal adenocarcinoma: relationship to tumour grade, stage and metastasis.
Using an immunoperoxidase procedure, we have examined the distribution of laminin and fibronectin in normal human large intestinal mucosa and in 50 cases of rectal adenocarcinoma for which extensive clinical follow up was available. In normal tissue, laminin staining was largely restricted to basement membranes, including that underlying the epithelial cells, whereas fibronectin was found in both basement membranes and surrounding connective tissue. In rectal carcinomas, basement membrane-like staining for laminin associated with tumour cells was found in only 27 out of the 50 cases studied. Statistical analysis showed that the presence of laminin-containing basement membranes was correlated with low histological grade (well-differentiated tumours), but not with stage (progression through the bowel wall and the development of lymph node metastases) and, in a highly significant way, with a reduced incidence of distant metastases and increased patient survival. Although fibronectin was found in tumour cell basement membranes where these were present, it was also found in the stroma of all 50 tumours. There was no apparent correlation between the presence of stromal fibronectin and grade, stage or development of metastases. Finally, attention is drawn to some of the technical difficulties in detecting basement membrane antigens in formalin-fixed tissue, the material most frequently available for retrospective study
Harbouring public good mutants within a pathogen population can increase both fitness and virulence
This is the final version of the article. Available from the publisher via the DOI in this record.Existing theory, empirical, clinical and field research all predict that reducing the virulence of individuals within a pathogen population will reduce the overall virulence, rendering disease less severe. Here, we show that this seemingly successful disease management strategy can fail with devastating consequences for infected hosts. We deploy cooperation theory and a novel synthetic system involving the rice blast fungus Magnaporthe oryzae. In vivo infections of rice demonstrate that M. oryzae virulence is enhanced, quite paradoxically, when a public good mutant is present in a population of high-virulence pathogens. We reason that during infection, the fungus engages in multiple cooperative acts to exploit host resources. We establish a multi-trait cooperation model which suggests that the observed failure of the virulence reduction strategy is caused by the interference between different social traits. Multi-trait cooperative interactions are widespread, so we caution against the indiscriminant application of anti-virulence therapy as a disease-management strategy.Natural Environment Research Council NE/E013007/3Natural Environment Research Council Doctoral training grantEngineering and Physical Sciences Research Council Doctoral training grant studentshipEuropean Research Council no. 294702 GENBLASTEuropean Research Council no. 647292 MathModEx
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