Direct patterning of organic conductors on knitted textiles for long-term electrocardiography.

Wearable sensors are receiving a great deal of attention as they offer the potential to become a key technological tool for healthcare. In order for this potential to come to fruition, new electroactive materials endowing high performance need to be integrated with textiles. Here we present a simple and reliable technique that allows the patterning of conducting polymers on textiles. Electrodes fabricated using this technique showed a low impedance contact with human skin, were able to record high quality electrocardiograms at rest, and determine heart rate even when the wearer was in motion. This work paves the way towards imperceptible electrophysiology sensors for human health monitoring

ππ\pi\pi scattering S wave from the data on the reaction π−p→π0π0n\pi^-p\to\pi^0\pi^0n

The results of the recent experiments on the reaction $\pi^-p\to\pi^0\pi^0n$ performed at KEK, BNL, IHEP, and CERN are analyzed in detail. For the I=0 $\pi\pi$ S wave phase shift $\delta^0_0$ and inelasticity $\eta^0_0$ a new set of data is obtained. Difficulties emerging when using the physical solutions for the $\pi^0\pi^0$ S and D wave amplitudes extracted with the partial wave analyses are discussed. Attention is drawn to the fact that, for the $\pi^0\pi^0$ invariant mass, m, above 1 GeV, the other solutions, in principle, are found to be more preferred. For clarifying the situation and further studying the $f_0(980)$ resonance thorough experimental investigations of the reaction $\pi^-p\to\pi^0\pi^0n$ in the m region near the $K\bar K$ threshold are required.Comment: 17 pages, 5 figure

Study of the ηπo\eta\pi^o system in the mass range up to 1200 MeV

The reaction $\pi^-p \to \eta\pi^o n$ has been studied with GAMS-2000 spectrometer in the secondary 38 GeV/c $\pi^-$-beam of the IHEP U-70 accelerator. Partial wave analysis of the reaction has been performed in the $\eta\pi^o$ mass range up to 1200 MeV. The $a_0(980)$-meson is seen as a sharp peak in S-wave. The $t$-dependence of $a_0(980)$ production cross section has been studied. Dominant production of the $a_0(980)$ at a small transfer momentum $t$ confirms the hypothesis of Achasov and Shestakov about significant contribution of the $\rho_2$ exchange ($I^GJ^{PC}=1^+2^{--}$) in the mechanism of $a_0(980)$ meson production in $t$-channel of the reaction.Comment: 4 pages, 3 figures, talk given at HADRON'9

The Pneumococcal Serine-Rich Repeat Protein Is an Intra-Species Bacterial Adhesin That Promotes Bacterial Aggregation In Vivo and in Biofilms

The Pneumococcal serine-rich repeat protein (PsrP) is a pathogenicity island encoded adhesin that has been positively correlated with the ability of Streptococcus pneumoniae to cause invasive disease. Previous studies have shown that PsrP mediates bacterial attachment to Keratin 10 (K10) on the surface of lung cells through amino acids 273–341 located in the Basic Region (BR) domain. In this study we determined that the BR domain of PsrP also mediates an intra-species interaction that promotes the formation of large bacterial aggregates in the nasopharynx and lungs of infected mice as well as in continuous flow-through models of mature biofilms. Using numerous methods, including complementation of mutants with BR domain deficient constructs, fluorescent microscopy with Cy3-labeled recombinant (r)BR, Far Western blotting of bacterial lysates, co-immunoprecipitation with rBR, and growth of biofilms in the presence of antibodies and competitive peptides, we determined that the BR domain, in particular amino acids 122–166 of PsrP, promoted bacterial aggregation and that antibodies against the BR domain were neutralizing. Using similar methodologies, we also determined that SraP and GspB, the Serine-rich repeat proteins (SRRPs) of Staphylococcus aureus and Streptococcus gordonii, respectively, also promoted bacterial aggregation and that their Non-repeat domains bound to their respective SRRPs. This is the first report to show the presence of biofilm-like structures in the lungs of animals infected with S. pneumoniae and show that SRRPs have dual roles as host and bacterial adhesins. These studies suggest that recombinant Non-repeat domains of SRRPs (i.e. BR for S. pneumoniae) may be useful as vaccine antigens to protect against Gram-positive bacteria that cause infection

Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters

3,4-Methylendioxymethamphetamine (MDMA) has both stimulatory and hallucinogenic properties which make its psychoactive effects unique and different from those of typical psychostimulant and hallucinogenic agents. The present study investigated the effects of MDMA on extracellular dopamine (DAex) and serotonin (5-HTex) levels in the striatum and prefrontal cortex (PFC) using in vivo microdialysis techniques in mice lacking DA transporters (DAT) and/or 5-HT transporters (SERT). subcutaneous injection of MDMA (3, 10 mg/kg) significantly increased striatal DAex in wild-type mice, SERT knockout mice, and DAT knockout mice, but not in DAT/SERT double-knockout mice. The MDMA-induced increase in striatal DAex in SERT knockout mice was significantly less than in wildtype mice. In the PFC, MDMA dose-dependently increased DAex levels in wildtype, DAT knockout, SERT knockout and DAT/SERT double-knockout mice to a similar extent. In contrast, MDMA markedly increased 5-HTex in wildtype and DAT knockout mice and slightly increased 5-HTex in SERT-KO and DAT/SERT double-knockout mice. The results confirm that MDMA acts at both DAT and SERT and increases DAex and 5-HTex

A study of the etapipi channel produced in central pp interactions at 450 GeV/c

The reaction pp -> pf (eta pi pi) ps has been studied at 450 GeV/c. There is clear evidence for an a2(1320)pi decay mode of the eta2(1645) and eta2(1870). In addition, there is evidence for an a0(980)pi$ decay mode of both resonances and an f2(1270)eta decay mode of the eta2(1870). No evidence is found for a JPC = 2++ a2(1320)pi wave.Comment: 15 pages, Latex, 4 Figures Branching ratio a2pi /f2 eta correcte

A study of the f0(1370), f0(1500), f0(2000) and f2(1950) observed in the centrally produced 4pi final states

The production and decay properties of the f0(1370), f0(1500), f0(2000) and f2(1950) have been studied in central pp interactions at 450 GeV/c. The dPT, phi and |t| distributions of these resonances are presented. For the J = 0 states, the f0(1370) and f0(2000) have similar dPT and phi dependences. These are different to the dPT and phi dependences of the f0(980), f0(1500) and f0(1710). For the J = 2 states the f2(1950) has different dependences to the f2(1270) and f2'(1520). This shows that the dPT and phi dependences are not just J phenomena.Comment: 14 pages, Latex, 4 Figure

A search for charmonium states produced in central pp interactions at 450 GeV/c

A search for centrally produced charmonium states has been presented. There is no significant evidence for any charmonium production. An upper limit of 2 nb is found for the cross section of chic production using the decay chic(1P)-> J/psi gamma.Comment: 10 pages, Latex, 4 Figure

A study of the centrally produced pi0pi0pi0 channel in pp interactions at 450 GeV/c

The reaction pp -> pf (pi0pi0pi0) ps has been studied at 450 GeV/c. The pi0pi0pi0 effective mass spectrum shows clear eta(547) and pi2(1670) signals. Branching ratios for the eta(547) and pi_2(1670) are given as well as upper limits for the decays of the omega(782), a1(1260) and a2(1320) into 3pi0.Comment: 10 pages, Latex, 4 Figure