27 research outputs found
ACVIM consensus statement on the diagnosis of immune-mediated hemolytic anemia in dogs and cats
Immune-mediated hemolytic anemia (IMHA) is an important cause of morbidity and mortality in dogs. IMHA also occurs in cats, although less commonly. IMHA is considered secondary when it can be attributed to an underlying disease, and as primary (idiopathic) if no cause is found. Eliminating diseases that cause IMHA may attenuate or stop immune-mediated erythrocyte destruction, and adverse consequences of long-term immunosuppressive treatment can be avoided. Infections, cancer, drugs, vaccines, and inflammatory processes may be underlying causes of IMHA. Evidence for these comorbidities has not been systematically evaluated, rendering evidence-based decisions difficult. We identified and extracted data from studies published in the veterinary literature and developed a novel tool for evaluation of evidence quality, using it to assess study design, diagnostic criteria for IMHA, comorbidities, and causality. Succinct evidence summary statements were
written, along with screening recommendations. Statements were refined by conducting 3 iterations of Delphi review with panel and task force members. Commentary was solicited from several professional bodies to maximize clinical applicability
before the recommendations were submitted. The resulting document is intended to provide clinical guidelines for diagnosis of, and underlying disease screening for, IMHA in dogs and cats. These should be implemented with consideration of animal, owner, and geographical factors
Priorities to inform research on marine plastic pollution in Southeast Asia
This is the final version. Available from Elsevier via the DOI in this record. Southeast Asia is considered to have some of the highest levels of marine plastic pollution in the world. It is therefore
vitally important to increase our understanding of the impacts and risks of plastic pollution to marine ecosystems and
the essential services they provide to support the development of mitigation measures in the region. An interdisciplinary, international network of experts (Australia, Indonesia, Ireland, Malaysia, the Philippines, Singapore, Thailand, the
United Kingdom, and Vietnam) set a research agenda for marine plastic pollution in the region, synthesizing current
knowledge and highlighting areas for further research in Southeast Asia. Using an inductive method, 21 research questions emerged under five non-predefined key themes, grouping them according to which: (1) characterise marine plastic pollution in Southeast Asia; (2) explore its movement and fate across the region; (3) describe the biological and
chemical modifications marine plastic pollution undergoes; (4) detail its environmental, social, and economic impacts;
and, finally, (5) target regional policies and possible solutions. Questions relating to these research priority areas highlight the importance of better understanding the fate of marine plastic pollution, its degradation, and the impacts and
risks it can generate across communities and different ecosystem services. Knowledge of these aspects will help support
actions which currently suffer from transboundary problems, lack of responsibility, and inaction to tackle the issue
from its point source in the region. Being profoundly affected by marine plastic pollution, Southeast Asian countries
provide an opportunity to test the effectiveness of innovative and socially inclusive changes in marine plastic governance, as well as both high and low-tech solutions, which can offer insights and actionable models to the rest of the
world.Natural Environment Research CouncilNational Research Foundation, Prime Minister’s Office (Singapore
Update on Canine and Feline Blood Donor Screening for Blood‐Borne Pathogens
An update on the 2005 American College of Veterinary Internal Medicine (ACVIM) Consensus Statement on blood donor infectious disease screening was presented at the 2015 ACVIM Forum in Indianapolis, Indiana, followed by panel and audience discussion. The updated consensus statement is presented below. The consensus statement aims to provide guidance on appropriate blood‐borne pathogen testing for canine and feline blood donors in North America
Geographic distribution of babesiosis among dogs in the United States and association with dog bites: 150 cases (2000-2003)
Peptide receptor radionuclide therapy in a patient with disabling non-functioning pituitary adenoma
A new 68Ga-labeled somatostatin analog containing two iodo-amino acids for dual somatostatin receptor subtype 2 and 5 targeting
Survey of vector-borne agents in feral cats and first report of Babesia gibsoni in cats on St Kitts, West Indies
Additional file 1: of Gene expression analysis at the onset of sex differentiation in turbot (Scophthalmus maximus)
Male and female length by age. Mean length (centimeters) by age (days post fertilization) is shown in a boxplot for males and females separately. Females are represented in magenta and males in blue. (PNG 6 kb