703 research outputs found

    The Influence of Bait to Ward Cath Result Rawai in the River Water Kampar Kiri Muara Sako Kelurahan Langgam Kecamatan Langgamkabupaten Pelalawan

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    The purpose of this study is to determine the best bait of three types of natural bait on longline catches in Sub Langgam District of LanggamPelalawan. This study was conducted in November 2016, in the waters of the river Kampar Kiri District of Muara Sako Village Idioms Langgam Pelalawan. The study was conducted using longline gear with different lures treatment is to feed crickets (Gryllidae), Sepat pearls (Trichogaster leeri), weaver ant eggs (Oecophylla). The method used in this research is the experimental method. The number of replications of 10 repetitions. The data were processed using a statistical test with SPSS 20.0 software on a test level of95% with normality test and one way ANOVA test. The results showed that different types of lures that affect the catch, type of fish caught by longline gear overall during the study based on the percentage amount (kg), namely: slice, juaro, Tapah, baung usual, baung mice, catfish. Fish juaro is a type of fish that most captured during the research that is equal to 17 tails of the overall catch

    advanced sensor signal feature extraction and pattern recognition for wire edm process monitoring

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    Wire electrical discharge machining (WEDM) is investigated in the perspective of zero-defect manufacturing with the scope to detect anomalous process conditions leading to typical defects generated during WEDM, i.e. the occurrence of lines and marks on the resulting workpiece surface. A multiple sensor monitoring system is employed to acquire high sampling rate sensorial data relative to signals of voltage and current in the gap between workpiece and wire electrode. An advanced signal processing methodology is implemented to extract and select the most relevant features useful to identify the undesired process conditions through a cognitive pattern recognition paradigm. (C) 2016 The Authors. Published by Elsevier B.V

    Hubungan Kematangan Reproduksi Dan Usia Saat Melahirkan Dengan Kejadian Bayi Berat Lahir Rendah (Bblr) Di Indonesia Tahun 2010

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    Background: Infant Low Birth Weight (LBW) is a major factor in increased mortality, morbidity and disability neonatal infants and children. One of biological characteristics of mothers that increases the risk of low birth weight is young gynecological age (reproductive maturity). Objective: This study aims to determine the relationship of reproductive maturity and maternal age at delivery with Infant LBW. Methods: The study design was cross-sectional with the outcome (LBW) clearly preceded by exposure (condition during pregnancy). Sample was 1562 subjects of Riskesdas 2010 namely married with first child. Birth weight data recorded in the health record book/KMS/KIA books. Multivariate analysis done by Cox regression. Result: Overall incidence of LBW was 6.1 percent. There were 11.8 percent of LBW with immaturity reproduction and 8.4 percent in women at risk on maternal age (<20 years)). The final result of multivariate analysis showed that women with immaturity reproduction and at risk on maternal age were 2.43 times having low birth weight baby compared to those with maturity reproduction and safe age of childbirth, controlled by education, iron tablet consumption, gestational age at first visit and number of ANC visits. Conclusions: Immaturity reproduction and at risk maternal age affect the incidence of LBW in Indonesia in 2010 adjusted by education, iron tablet consumption, gestational age at first visit and the number of ANC visits

    Nanotechnology in machining processes: recent advances

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    In this brief survey, the use of nanoparticle dispersions in machining processes is discussed and the relevant applicational performances are analysed and related to the structural and chemical composition of the embedded nanophase. The paper is divided in two basic parts. In the former, the metalworking nanofluids are classified with respect to the physico-chemical properties of the nanostructured phase suspended in the base fluid. In the latter, some aspects concerning the production of metalworking nanofluids are analysed and a new green and economically viable technique based on a cementation process for metal nanoparticle synthesis is proposed as an alternative approach to the conventional manufacturing techniques

    Maternal Death in Indonesia: Follow-up Study of the 2010 Indonesia Population Census

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    Background: Among ASEAN countries, Indonesia is the country with high maternal mortality ratio (MMR) and unable to reach target of reduction of MMR. In order to reduce the MMR target, the government of Indonesia needs evidence to evaluate and design the maternal health program. Objective: The study aims to answers specific issues of who, when, where and why maternal death occurred in Indonesia in order to understand the effective policy and health program decisions. Methods: The 2010 Indonesia Population Census identified pregnancy-related deaths occurring in the household from 1 January 2009 until the date of census (May 2010). The follow-up study revisited almost half of households reporting pregnancy-related deaths to be accounted as samples (4167 of 8464). Basic information related to cause of death were collected by trained data collector using verbal autopsy approach. The information was converted to cause of death defined by medical doctor using WHO ICD-10 rules. The underlying cause of death was later analysed. Result: The highest risk of maternal death was adolescents who were pregnant under 15 years old. The maternal death mostly occurred at postpartum period (56%), 57 percent occurred at hospitals and 31.3 percent at home. Oedema, proteinuria and hypertensive disorder in pregnancy were at 27 percent, whereas complication during labour and delivery problems were accounted for 26 percent. The pattern of maternal causes of death varies between regions. Conclusion: Maternal health program has not been considered as general plan of intervention. It is imperative to consider considered by pattern of characteristics and cause of maternal death and region for effective interventions

    Hasil Cek Similiritas Separation of squalene rich fraction from palm oil fatty acid distillate (PFAD): A review

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    Palm Oil Fatty Acid Distillate (PFAD) is a by-product of the palm oil industry which has many potential bioactive compounds such as vitamin E, phytosterols and squalene. To obtain multi-component bioactive compounds, saponification and extraction processes are required. The purpose of this study was to identify a review of the comparison of several methods that are more optimal in separating the Squalene-Rich Fraction from Palm Oil Fatty Acid Distillate (PFAD). The study uses the systematic literature review method, where the review will study and compare several journal descriptions regarding comparisons in managing the optimal separation of the squalene fraction from the three types of methods offered, namely the method using solvents, the method using high pressure supercritical fluid extraction and the isolation of squalene method using Saccharomyces cerevisiae strains. This review presents a descriptive analysis of the advantages and disadvantages of the three methods. The study compared three methods for separating the squalene-rich fraction. The review suggests that the safest method to use is separation with low temperature solvents or the so-called low temperature solvent crystallization. Reviews show that this method will not destroy bioactive compounds which are easily oxidized, be easy to apply, require low production cost and capable of producing high purity squalene-rich fractions

    A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma

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    Approximately half of high-risk neuroblastoma is characterized by MYCN amplification. N-Myc promotes tumor progression by inducing cell growth and inhibiting differentiation. MYCN has also been shown to play an active role in mitochondrial metabolism, but this relationship is not well understood. Although N-Myc is a known driver of the disease, it remains a target for which no therapeutic drug exists. Here, we evaluated a novel MYCN-specific antigene PNA oligonucleotide (BGA002) in MYCN-amplified (MNA) or MYCN-expressing neuroblastoma and investigated the mechanism of its antitumor activity. MYCN mRNA and cell viability were reduced in a broad set of neuroblastoma cell lines following BGA002 treatment. Furthermore, BGA002 decreased N-Myc protein levels and apoptosis in MNA neuroblastoma. Analysis of gene expression data from patients with neuroblastoma revealed that MYCN was associated with increased reactive oxygen species (ROS), downregulated mitophagy, and poor prognosis. Inhibition of MYCN caused profound mitochondrial damage in MNA neuroblastoma cells through downregulation of the mitochondrial molecular chaperone TRAP1, which subsequently increased ROS. Correspondingly, inhibition of MYCN reactivated mitophagy. Systemic administration of BGA002 downregulated N-Myc and TRAP1, with a concomitant decrease in MNA neuroblastoma xenograft tumor weight. In conclusion, this study highlights the role of N-Myc in blocking mitophagy in neuroblastoma and in conferring protection to ROS in mitochondria through upregulation of TRAP1. BGA002 is a potently improved MYCN-specific antigene oligonucleotide that reverts N-Myc\u2013dysregulated mitochondrial pathways, leading to loss of the protective effect of N-Myc against mitochondrial ROS. Significance: A second generation antigene peptide oligonucleotide targeting MYCN induces mitochondrial damage and inhibits growth of MYCN-amplified neuroblastoma cells
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