Consistent SDNs through Network State Fuzzing

The conventional wisdom is that a software-defined network (SDN) operates under the premise that the logically centralized control plane has an accurate representation of the actual data plane state. Nevertheless, bugs, misconfigurations, faults or attacks can introduce inconsistencies that undermine correct operation. Previous work in this area, however, lacks a holistic methodology to tackle this problem and thus, addresses only certain parts of the problem. Yet, the consistency of the overall system is only as good as its least consistent part. Motivated by an analogy of network consistency checking with program testing, we propose to add active probe-based network state fuzzing to our consistency check repertoire. Hereby, our system, PAZZ, combines production traffic with active probes to continuously test if the actual forwarding path and decision elements (on the data plane) correspond to the expected ones (on the control plane). Our insight is that active traffic covers the inconsistency cases beyond the ones identified by passive traffic. PAZZ prototype was built and evaluated on topologies of varying scale and complexity. Our results show that PAZZ requires minimal network resources to detect persistent data plane faults through fuzzing and localize them quickly

Unifying rational models of categorization via the hierarchical Dirichlet process

Models of categorization make different representational assumptions, with categories being represented by prototypes, sets of exemplars, and everything in between. Rational models of categorization justify these representational assumptions in terms of different schemes for estimating probability distributions. However, they do not answer the question of which scheme should be used in representing a given category. We show that existing rational models of categorization are special cases of a statistical model called the hierarchical Dirichlet process, which can be used to automatically infer a representation of the appropriate complexity for a given category.Thomas Griffiths, Kevin Canini, Adam Sanborn, Dan Navarr

Biostimulants promoting growth of Vicia faba L. seedlings: inulin coated ZnO nanoparticles

In the present contribution, inulin coated ZnO nanoparticles (ZnO@inu NPs) were investigated for their potential application on crop production systems, by appraisal of their biostimulating effects on Vicia faba L (faba bean). Naked and coated ZnO NPs were synthesized according to purposely implemented eco-friendly protocols and characterized with multiple techniques to determine their crystallographic phase, average particle size, and degree of coating. Faba beans were grown in culture medium supplemented with NPs at 50 or 100 mg kg−1, using ZnO NPs alone, inulin alone, a mixture of the two, or ZnO@inu NPs. Seed germination rate and biometric evaluations on seedlings were carried out, together with Zn localization in the plant tissues. cellular and molecular effects were ascertained by analyses of photosynthetic pigments, cytotoxicity, genotoxicity, viability, induction of oxidative stress and tissue damage, antioxidant response, and modulation of gene expression. these combined studies indicated a potential role of ZnO@inu NPs in promoting growth and development of V. faba seedlings, acting at a post-germinative phase, probably by stimulating the stem cell mitosis. Finally, inulin as a coating agent for the ZnO NPs favored the bioavailability and adsorption of the nanomaterials into the plant tissues, without altering their bioactivity but mitigating any adverse side effect. Graphical Abstract: [Figure not available: see fulltext.]

Inter-domain networking innovation on steroids: Empowering IXPs with SDN capabilities

While innovation in inter-domain routing has remained stagnant for over a decade, Internet Exchange Points (IXPs) are consolidating their role as economically advantageous interconnection points for reducing path latencies and exchanging ever increasing amounts of traffic. As such, IXPs appear as a natural place to foster network innovation and assess the benefits of Software-Defined Networking (SDN), a recent technological trend that has already boosted innovation within data-center networks. In this paper, we give a comprehensive overview of use cases for SDN at IXPs, which leverage the superior vantage point of an IXP to introduce advanced features like load-balancing and DDoS mitigation. We discuss the benefits of SDN solutions by analyzing real-world data from one of the largest IXPs. We also leverage insights into IXP operations to not only shape benefits for members but also for operators.This research is (in part) supported by European Union’s Horizon 2020 research and innovation programme under the ENDEAVOUR project (grant agreement 644960).This is the author accepted manuscript. The final version is available from IEEE via https://doi.org/ 10.1109/MCOM.2016.758827

Pointing error and field of view of AERONET CIMEL-318 sun photometers

Resumen de la comunicación oral presentada en: 1st Iberian Meeting on Aerosol Science and Technology – RICTA 2013, celebrado del 1 al 3 de julio de 2013 en Évora, Portugal

Correction to: Human behavior and Homo-mammal interactions at the first European peopling: new evidence from the Pirro Nord site (Apricena, Southern Italy)

In the original publication of this article, one of the author names was incorrectly captured. The first name should be Razika, then family name should be Chelli–Cheheb

Facemasks, Hand Hygiene, and Influenza among Young Adults: A Randomized Intervention Trial

Limited vaccine availability and the potential for resistance to antiviral medications have led to calls for establishing the efficacy of non-pharmaceutical measures for mitigating pandemic influenza. Our objective was to examine if the use of face masks and hand hygiene reduced rates of influenza-like illness (ILI) and laboratory-confirmed influenza in the natural setting. A cluster-randomized intervention trial was designed involving 1,178 young adults living in 37 residence houses in 5 university residence halls during the 2007–2008 influenza season. Participants were assigned to face mask and hand hygiene, face mask only, or control group during the study. Discrete-time survival models using generalized estimating equations to estimate intervention effects on ILI and confirmed influenza A/B infection over a 6-week study period were examined. A significant reduction in the rate of ILI was observed in weeks 3 through 6 of the study, with a maximum reduction of 75% during the final study week (rate ratio [RR] = 0.25, [95% CI, 0.07 to 0.87]). Both intervention groups compared to the control showed cumulative reductions in rates of influenza over the study period, although results did not reach statistical significance. Generalizability limited to similar settings and age groups. Face masks and hand hygiene combined may reduce the rate of ILI and confirmed influenza in community settings. These non-pharmaceutical measures should be recommended in crowded settings at the start of an influenza pandemic

The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011

Background: Previous controlled studies on the effect of non-pharmaceutical interventions (NPI) - namely the use of facemasks and intensified hand hygiene - in preventing household transmission of influenza have not produced definitive results. We aimed to investigate efficacy, acceptability, and tolerability of NPI in households with influenza index patients. Methods: We conducted a cluster randomized controlled trial during the pandemic season 2009/10 and the ensuing influenza season 2010/11. We included households with an influenza positive index case in the absence of further respiratory illness within the preceding 14 days. Study arms were wearing a facemask and practicing intensified hand hygiene (MH group), wearing facemasks only (M group) and none of the two (control group). Main outcome measure was laboratory confirmed influenza infection in a household contact. We used daily questionnaires to examine adherence and tolerability of the interventions. Results: We recruited 84 households (30 control, 26 M and 28 MH households) with 82, 69 and 67 household contacts, respectively. In 2009/10 all 41 index cases had a influenza A (H1N1) pdm09 infection, in 2010/11 24 had an A (H1N1) pdm09 and 20 had a B infection. The total secondary attack rate was 16% (35/218). In intention-totreat analysis there was no statistically significant effect of the M and MH interventions on secondary infections. When analysing only households where intervention was implemented within 36 h after symptom onset of the index case, secondary infection in the pooled M and MH groups was significantly lower compared to the control group (adjusted odds ratio 0.16, 95% CI, 0.03-0.92). In a per-protocol analysis odds ratios were significantly reduced among participants of the M group (adjusted odds ratio, 0.30, 95% CI, 0.10-0.94). With the exception of MH index cases in 2010/11 adherence was good for adults and children, contacts and index cases. Conclusions: Results suggest that household transmission of influenza can be reduced by the use of NPI, such as facemasks and intensified hand hygiene, when implemented early and used diligently. Concerns about acceptability and tolerability of the interventions should not be a reason against their recommendation

Modeling Within-Host Dynamics of Influenza Virus Infection Including Immune Responses

Influenza virus infection remains a public health problem worldwide. The mechanisms underlying viral control during an uncomplicated influenza virus infection are not fully understood. Here, we developed a mathematical model including both innate and adaptive immune responses to study the within-host dynamics of equine influenza virus infection in horses. By comparing modeling predictions with both interferon and viral kinetic data, we examined the relative roles of target cell availability, and innate and adaptive immune responses in controlling the virus. Our results show that the rapid and substantial viral decline (about 2 to 4 logs within 1 day) after the peak can be explained by the killing of infected cells mediated by interferon activated cells, such as natural killer cells, during the innate immune response. After the viral load declines to a lower level, the loss of interferon-induced antiviral effect and an increased availability of target cells due to loss of the antiviral state can explain the observed short phase of viral plateau in which the viral level remains unchanged or even experiences a minor second peak in some animals. An adaptive immune response is needed in our model to explain the eventual viral clearance. This study provides a quantitative understanding of the biological factors that can explain the viral and interferon kinetics during a typical influenza virus infection