From Deutsche Zeitschrift to International Journal of Legal Medicine-100 years of legal medicine through the lens of journal articles : Part 3: Zeitschrift für Rechtsmedizin-Journal of Legal Medicine from 1970 to 1990.

From volume 67 (1970) onwards, the journal appeared under the new bilingual title Zeitschrift für Rechtsmedizin-Journal of Legal Medicine. The editorial board was expanded and internationalised. From 1970 to 1990, 1416 articles were published in 36 volumes. 1036 articles were in German and 380 in English. The authors of 411 articles came from non-German-speaking countries. Compared to the periods under review in the first two parts of our article series, the proportion of papers on forensic genetics increased significantly between 1970 and 1990, with a small increase in publications on the identification of unknown dead bodies. An opposite trend was observed in the articles on forensic psychiatry and psychology, sexual medicine and social medicine. This development reflects a further sharpening of the discipline's profile

From Deutsche Zeitschrift to International Journal of Legal Medicine-100 years of legal medicine through the lens of journal articles : Part 2: Deutsche Zeitschrift für die gesamte gerichtliche Medizin from 1948 to 1969.

The interruption of the publication of the Deutsche Zeitschrift für die gesamte gerichtliche Medizin due to the war ended with volume 39 for the years 1948/1949. Until volume 66/1969, the journal appeared unchanged under the historical title. The 912 publications contained in the 28 volumes of these two decades cover topics from the main fields of forensic medicine, but also from related and unrelated disciplines. The topic-specific analysis of the publications shows a shift of the research focus in the German institutes since the post-war period. This is most evident in the decline in the number of publications from the fields of scientific and technical criminalistics as well as forensic psychiatry and psychology. An opposite trend with a significant increase in scientific papers was observed in alcohology, forensic genetics and traffic medicine. While the evaluated publications on most topics contain new findings that are still valid today, the use of blood group characteristics for forensic purposes came to an end as a result of the introduction of DNA analysis

From Deutsche Zeitschrift to International journal of legal medicine-100 years of legal medicine through the lens of journal articles, Part 4: International journal of legal medicine from 1990 to 2022.

This is the fourth and final paper in a series related to the analysis of articles published in this journal during its first 100 years of activity. This article covers the time span from 1990 to 2022. It is important to note that, given the period covered by this analysis, it does not aim to provide a historical overview but rather an examination of the most recent trends in our discipline compared to the past. Between 1990 (Volume 104) and 2022 (Volume 136), 4004 articles were published in the International Journal of Legal Medicine (IJLM) across 33 volumes. This corresponds to 53% of all the articles published since the launch of the journal. When compared to the period from 1970 to 1990, some categories no longer appear to be as relevant (e.g., sexual medicine, 1 article; social medicine, 0 articles; biography, 3 articles; history, 4 articles). Conversely, the most recent period has shown an increasing importance in forensic genetics (1388 articles) and the emergence of new significant topics that merit their own classification, such as age estimation (286 articles), forensic anthropology (189 articles), forensic imaging (150 articles), and forensic entomology (90 articles)

Investigation of Heavy Metals in Zebrafish Tissue by Total Reflection X-ray Fluorescence

Heavy metals are present in the environment, in many consumer products and can be found in food. Some heavy metals like zinc and copper are essential for enzymatic and metabolic function while others like lead and mercury are toxic and interfere with biological pathways. Zebrafish are a very popular model organism for monitoring toxicity of heavy metals and investigating vertebrate development. In this study we explore the possibility of using total reflection X-ray fluorescence spectrometry to analyze histological sections of zebrafish embryos after exposure to nickel and lead. A methacrylate resin embedding protocol and a paraffin embedding protocol were evaluated as possible options for sample preparation for TXRF analysis of zebrafish embryos. It was found that paraffin is the superior material after an alkaline phosphatase stain was introduced. The stain made the normally transparent fish embryo embedded in paraffin clearly visible on the sample reflector material thus allowing for easy positioning and identification of the area of interest

Anisotropy and XKS-splitting from geodynamic models of double subduction: Testing the limits of interpretation

In this study, we develop three-dimensional geodynamic models to predict XKS-splitting for double subduction scenarios characterized by two outward dipping slabs. These models are highly relevant in various realistic settings, such as the central Mediterranean. We focus on the analysis of XKS-splitting, a key geophysical observable used to infer seismic anisotropy and mantle flow patterns predicted from these geodynamic models. Our geodynamic models simulate the concurrent subduction of two identical oceanic plates which are separated by a continental plate. The variation of the separating plate strength, cause a transition from a retreating to a stationary trench. The models provide detailed insights into the temporal evolution of mantle flow patterns, especially the amount of trench parallel flow, induced by these double subduction scenarios. In a second step, we use the well-known D-Rex model (Kaminski et al., 2004) to efficiently estimate the CPO development in response to plastic deformation produced by mantle flow. Based on the results of the D-Rex model, which includes the full elastic tensor of a deformed multiphase polycrystalline mantle aggregate within the three-dimensional model, we obtain synthetic apparent splitting parameters at receivers placed at the surface by applying multiple-layer anisotropic waveform modeling. Employing analytical techniques, we show the ambiguous nature of apparent splitting parameters, as already suggested by previous studies based on numerical modeling. In the light of the results, we postulate that a meaningful inversion, based on the commonly applied 2-layer anisotropic model, requires additional constraints on fast-axis orientation or strength of anisotropy (delay time). Finally, we show that constraints from our texture simulations (i.e., the integrated delay time) can be used to achieve unique 2-layer models that perfectly fit the synthetic observables. Such models could serve as reference for the interpretation of the observations. Our study highlights the necessity of combining geodynamic modeling and XKS-splitting analysis to shed light on complex upper mantle flow patterns such as those that might occur around subduction zones

Cosmic multi-muon events observed in the underground CERN-LEP tunnel with the ALEPH experiment

Multimuon events have been recorded with the ALEPH-detector, located 140 m underground, in parallel with e$^+$e$^-$ data taking. Benefitting from the high spatial and momentum resolution of the ALEPH tracking chambers narrowly spaced muons in high multiplicity bundles could be analysed. The bulk of the data can be successfully described by standard production phenomena. The multiplicity distribution favors, though not with very high significance, a chemical composition which changes from light to heavier elements with increasing energy around the ``knee". The five highest multiplicity events, with up to 150 muons within an area of $\sim$ 8 m$^2$, occur with a frequency which is almost an order of magnitude above the simulation. To establish a possible effect, more of these events should be recorded with a larger area detector

On the segmentation and classification of hand radiographs

This research is part of a wider project to build predictive models of bone age using hand radiograph images. We examine ways of finding the outline of a hand from an X-ray as the first stage in segmenting the image into constituent bones. We assess a variety of algorithms including contouring, which has not previously been used in this context. We introduce a novel ensemble algorithm for combining outlines using two voting schemes, a likelihood ratio test and dynamic time warping (DTW). Our goal is to minimize the human intervention required, hence we investigate alternative ways of training a classifier to determine whether an outline is in fact correct or not. We evaluate outlining and classification on a set of 1370 images. We conclude that ensembling with DTW improves performance of all outlining algorithms, that the contouring algorithm used with the DTW ensemble performs the best of those assessed, and that the most effective classifier of hand outlines assessed is a random forest applied to outlines transformed into principal components

A comparison of numerical surface topography calculations in geodynamic modelling: an evaluation of the ‘sticky air' method

Calculating surface topography in geodynamic models is a common numerical problem. Besides other approaches, the so-called ‘sticky air' approach has gained interest as a free-surface proxy at the top boundary. The often used free slip condition is thereby vertically extended by introducing a low density, low viscosity fluid layer. This allows the air/crust interface to behave in a similar manner to a true free surface. We present here a theoretical analysis that provides the physical conditions under which the sticky air approach is a valid approximation of a true free surface. Two cases are evaluated that characterize the evolution of topography on different timescales: (1) isostatic relaxation of a cosine perturbation and (2) topography changes above a rising plume. We quantitatively compare topographies calculated by six different numerical codes (using finite difference and finite element techniques) using three different topography calculation methods: (i) direct calculation of topography from normal stress, (ii) body-fitting methods allowing for meshing the topography and (iii) Lagrangian tracking of the topography on an Eulerian grid. It is found that the sticky air approach works well as long as the term (ηst/ηch)/(hst/L)3 is sufficiently small, where ηst and hst are the viscosity and thickness of the sticky air layer, and ηch and L are the characteristic viscosity and length scale of the model, respectively. Spurious lateral fluctuations of topography, as observed in some marker-based sticky air approaches, may effectively be damped by an anisotropic distribution of markers with a higher number of markers per element in the vertical than in the horizontal directio