The current state of the organization of work of sports sections in neskolkomi universities

Organization of University sports clubs outside of class time is effective ways this principle for young students. Attracting students to occupations in sports sections is one of the most effective ways to develop this principle among young people. The lack in practice of scientifically grounded strategy of development of student sport, the mechanisms of its interaction with the system of physical education, creates the methodological and organizational problems that require researchОрганизация вузовских спортивных секций во внеучебное время является эффективным способов спортизации учащейся молодежи. Привлечение студентов к занятиям в спортивных секциях служит одним из наиболее эффективных способов развития спортизации среди молодежи. Отсутствие в практике научно обоснованной стратегии развития студенческого спорта, механизмов его взаимодействия с системой физического воспитания, порождает методологические и организационные проблемы, требующие проведения научных исследовани

Engaging Undergraduates in Science Research: Not Just About Faculty Willingness.

Despite the many benefits of involving undergraduates in research and the growing number of undergraduate research programs, few scholars have investigated the factors that affect faculty members' decisions to involve undergraduates in their research projects. We investigated the individual factors and institutional contexts that predict faculty members' likelihood of engaging undergraduates in their research project(s). Using data from the Higher Education Research Institute's 2007-2008 Faculty Survey, we employ hierarchical generalized linear modeling to analyze data from 4,832 science, technology, engineering, and mathematics (STEM) faculty across 194 institutions to examine how organizational citizenship behavior theory and social exchange theory relate to mentoring students in research. Key findings show that faculty who work in the life sciences and those who receive government funding for their research are more likely to involve undergraduates in their research project(s). In addition, faculty at liberal arts or historically Black colleges are significantly more likely to involve undergraduate students in research. Implications for advancing undergraduate research opportunities are discussed

ПРИМЕНЕНИЕ ПОЧЕЧНО-ЗАМЕСТИТЕЛЬНОЙ ТЕРАПИИ У ДЕТЕЙ КЕМЕРОВСКОЙ ОБЛАСТИ

The paper features comparative outcomes of applying different methods of renal replacement therapy for acute renal failure and chronic renal failure in children at the pediatric dialysis unit of the Russian children’s hospital «Zonal perinatal centre» in Novokuznetsk. The use of renal replacement therapy as an optimal method for achieving adequate and effective replacement of kidney function is validated. There are treated 58 children, 37 patients with acute kidney injury and 21 with terminal chronic renal failure. Acute renal failure was prevailed in preschoolers of 1–6 years old children – 24 (64,8 %), the terminal chronic renal failure in school children and teenagers – 16 (76,2 %). The renal replacement therapy used in 5 (13,5 %) patients with septic diseases, and in 6 (16,2 %) patients with poisons diseases. Methods of renal replacement therapy is effectively cleansing of the blood in critically ill patients. This method can reduce the rate of mortality and effectively adjust homeostasis in severe infections, septic diseases, multiple organ dysfunction syndrome and in patients with poisons diseases. Application of peritoneal dialysis allows as effective replacement of renal function in the children with difficulty vascular access.Представлены результаты применения методов почечно-заместительной терапии детям с острой и хронической почечной недостаточностью в отделении анестезиологии-реанимации МБЛПУ «Зональный перинатальный центр» г. Новокузнецка в 2005–2015 гг. как оптимальных методов, позволяющих обеспечить адекватное и эффективное замещение почечной функции и детоксикацию при критических состояниях. Пролечено 58 детей, из них 37 с острым почечным повреждением и 21 с терминальной хронической почечной недостаточностью. Острая почечная недостаточность превалировала у дошкольников 1–6 лет – 24 (64,8 %) случая, терминальная хроническая почечная недостаточность у школьников и подростков – 16 (76,2 %). По внепочечным показаниям методы ПЗТ применялись у 5 (13,5 %) пациентов с гнойно-септическими заболеваниями и у 6 (16,2 %) токсикологических больных. Методы почечно-заместительной терапии дают возможность безопасно и эффективно проводить очищение крови у критически тяжелых пациентов, снизить летальность, эффективно корректировать гомеостаз при тяжелых инфекционных заболеваниях, гнойно-септических процессах, синдроме полиорганной недостаточности, а также у токсикологических больных. Применение перитонеального диализа позволяет обеспечить адекватное и эффективное замещение почечной функции при сложности постановки сосудистого доступа у ребенка

ВОЗМОЖНОСТИ СТАБИЛОГРАФИЧЕСКОГО ИССЛЕДОВАНИЯ ДЛЯ ОЦЕНКИ УСТОЙЧИВОСТИ ВЕРТИКАЛЬНОЙ ПОЗЫ У РАБОТНИКОВ, ЗАНЯТЫХ В УСЛОВИЯХ ВОЗДЕЙСТВИЯ ПРОИЗВОДСТВЕННОЙ ВИБРАЦИИ

The aim of this study was to evaluate the possibility of using stabilography for identifying postural imbalance in workers exposed to industrial vibration. A total of 97 workers of the JSC «Minsk Automobile Plant» exposed to industrial vibration were recruited. The main stabilographic parameters characterizing the stability of the vertical posture and the degree of plantar information used for maintaining balance of workers were analyzed. We identified postural changes indicating the disturbances of proprioceptive sensitivity in workers exposed to industrial vibration more than 5 years.Проведенное исследование заключалось в оценке возможностей стабилографического исследования для выявления постуральной дисбаланса у рабочих, подвергающихся воздействию промышленной вибрации. Проанализированы основные стабилографические параметры, характеризующие устойчивость вертикальной позы, а также плантарный коэффициент, характеризующий степень использования плантарной информации для поддержания равновесия. Авторы определили постуральные изменения, указывающие на нарушения проприоцептивной чувствительности у рабочих, подвергающихся воздействию промышленной вибрации более 5 лет

An apicobasal gradient of Rac activity determines protrusion form and position

Each cell within a polarised epithelial sheet must align and correctly position a wide range of subcellular structures, including actin-based dynamic protrusions. Using in vivo inducible transgenes that can sense or modify Rac activity, we demonstrate an apicobasal gradient of Rac activity that is required to correctly form and position distinct classes of dynamic protrusion along the apicobasal axis of the cell. We show that we can modify the Rac activity gradient in genetic mutants for specific polarity proteins, with consequent changes in protrusion form and position and additionally show, using photoactivatable Rac transgenes, that it is the level of Rac activity that determines protrusion form. Thus, we demonstrate a mechanism by which polarity proteins can spatially regulate Rac activity and the actin cytoskeleton to ensure correct epithelial cell shape and prevent epithelial-to-mesenchymal transitions

Temporal and structural genetic variation in reindeer (Rangifer tarandus) associated with the pastoral transition in Northwestern Siberia

Funding Information NordForsk. Grant Number: 76915 ERC Advanced Grant. Grant Numbers: 295458, ESRC ES/, M011054/1 JPI HUMANOR ERC Starting GrantPeer reviewedPublisher PD

The Undergraduate–Postgraduate–Faculty Triad: Unique Functions and Tensions Associated with Undergraduate Research Experiences at Research Universities

We present an exploratory study of how undergraduates' involvement in research influences postgraduates (i.e., graduate and postdoctoral researchers) and faculty. We used a qualitative approach to examine the relationships among undergraduates, postgraduates, and the faculty head in a research group. In this group, undergraduates viewed postgraduates as more approachable than the faculty head both literally and figuratively. Mentorship by postgraduates presented unique challenges for undergraduates, including unrealistic expectations and varying abilities to mentor. The postgraduates and faculty head concurred that undergraduates contributed to the group's success and served as a source of frustration. Postgraduates appreciated the opportunity to observe multiple approaches to mentoring as they saw the faculty head and other postgraduates interact with undergraduates. The faculty head viewed undergraduate research as important for propagating the research community and for gaining insights into undergraduates and their postgraduate mentors. These results highlight how the involvement of undergraduates and postgraduates in research can limit and enhance the research experiences of members of the undergraduate–postgraduate–faculty triad. A number of tensions emerge that we hypothesize are intrinsic to undergraduate research experiences at research universities. Future studies can focus on determining the generalizability of these findings to other groups and disciplines

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes

Most migrating cells extrude their front by the force of actin polymerization. Polymerization requires an initial nucleation step, which is mediated by factors establishing either parallel filaments in the case of filopodia or branched filaments that form the branched lamellipodial network. Branches are considered essential for regular cell motility and are initiated by the Arp2/3 complex, which in turn is activated by nucleation-promoting factors of the WASP and WAVE families. Here we employed rapid amoeboid crawling leukocytes and found that deletion of the WAVE complex eliminated actin branching and thus lamellipodia formation. The cells were left with parallel filaments at the leading edge, which translated, depending on the differentiation status of the cell, into a unipolar pointed cell shape or cells with multiple filopodia. Remarkably, unipolar cells migrated with increased speed and enormous directional persistence, while they were unable to turn towards chemotactic gradients. Cells with multiple filopodia retained chemotactic activity but their migration was progressively impaired with increasing geometrical complexity of the extracellular environment. These findings establish that diversified leading edge protrusions serve as explorative structures while they slow down actual locomotion