6,214 research outputs found

    Thermal tuning of organic dye lasers

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    Non-mechanical method for tuning liquid laser wavelengths involves electrically varying temperature of laser medium. Technique is used to investigate behavior of laser dyes, and may lead to broad, tunable, light source for spectroscopy measurements of long path absorption

    Augmented renal clearance is not a risk factor for mortality in Enterobacteriaceae bloodstream infections treated with appropriate empiric antimicrobials

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    The main objective of the study was to assess whether augmented renal clearance was a risk factor for mortality in a cohort of patients with Enterobacteriaceae sepsis, severe sepsis, or septic shock that all received appropriate antimicrobial therapy within 12 hours. Using a retrospective cohort from Barnes-Jewish Hospital, a 1,250-bed teaching hospital, we collected data on individuals with Enterobacteriaceae sepsis, severe sepsis, and septic shock who received appropriate initial antimicrobial therapy between June 2009 and December 2013. Clinical outcomes were compared according to renal clearance, as assessed by Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formulas, sepsis classification, demographics, severity of illness, and comorbidities. We identified 510 patients with Enterobacteriaceae bacteremia and sepsis, severe sepsis, or septic shock. Sixty-seven patients (13.1%) were nonsurvivors. Augmented renal clearance was uncommon (5.1% of patients by MDRD and 3.0% by CKD-EPI) and was not associated with increased mortality. Our results are limited by the absence of prospective determination of augmented renal clearance. However, in this small cohort, augmented renal clearance as assessed by MDRD and CKD-EPI does not seem to be a risk factor for mortality in patients with Enterobacteriaceae sepsis. Future studies should assess this finding prospectively

    Discussing the Relationship Between Venue and Learning in the Education of Health Professionals

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    Objectives: To discuss the relationship between the education of health professionals and the off-campus venues where their practicums or internships are served, in order to modify and implement innovations in the curriculum to meet identified needs

    Electrical behavior of GaAs–AlAs heterostructures

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    We report an experimental study of the electrical behavior of GaAs–AlAs–GaAs heterostructures grown by metal–organic chemical vapor deposition. The structures consisted of a layer of AlAs several thousand angstroms thick sandwiched between layers of GaAs which were a few microns thick. The top layer of GaAs was doped degenerately n-type with Se, while the bottom layer was nondegenerately doped. Capacitance–voltage (C–V) and curent–voltage (I–V) curves were obtained as a function of temperature, illumination, and rate of data acquisition. Deep-level transient spectroscopy (DLTS) measurements were also made. The C–V showed hysteresis near zero bias with the capacitance being larger when the voltage was swept from reverse to forward bias in the dark. The C–V displayed a light sensitive peak near zero bias. With illumination, the capacitance was greater, and no hysteresis was observed. We explain these phenomena as being due to deep levels near the AlAs–GaAs interface; DLTS has confirmed this. I–V curves taken in darkness also showed hysteresis. We take this as further evidence of deep levels. Additionally, capacitance failed to level off in reverse bias, indicating a lack of inversion in the samples

    Experimental pig-to-pig transmission dynamics for African swine fever virus, Georgia 2007/1 strain

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    African swine fever virus (ASFV) continues to cause outbreaks in domestic pigs and wild boar in Eastern European countries. To gain insights into its transmission dynamics, we estimated the pig-to-pig basic reproduction number (R 0) for the Georgia 2007/1 ASFV strain using a stochastic susceptible-exposed-infectious-recovered (SEIR) model with parameters estimated from transmission experiments. Models showed that R 0 is 2·8 [95% confidence interval (CI) 1·3–4·8] within a pen and 1·4 (95% CI 0·6–2·4) between pens. The results furthermore suggest that ASFV genome detection in oronasal samples is an effective diagnostic tool for early detection of infection. This study provides quantitative information on transmission parameters for ASFV in domestic pigs, which are required to more effectively assess the potential impact of strategies for the control of between-farm epidemic spread in European countries.ISSN:0950-2688ISSN:1469-440

    Supping with a long spoon in the Indian Ocean: the negotiation of the 1972 Agreement on Economic and Technical Cooperation between Mauritius and the People’s Republic of China

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    This is the final version. Available on open access from Routledge via the DOI in this recordAgainst the backdrop of the Soviet Union’s 1970s reengagement with Africa through the Indian Ocean, this article investigates the overlapping extensions of aid and technical assistance to the island nation of Mauritius, focusing primarily on the unprecedented 1972 infrastructural development offer by the People’s Republic of China. By analysing the minutes of the Sino-Mauritian Agreement on Economic and Technical Cooperation’s negotiations as found in the United Kingdom’s Foreign and Colonial Office dossiers, this paper examines Chinese aid diplomacy to Africa in a period which saw its admission to the United Nations, its realignment against the USSR, and the concomitant latticed transformations of its aid diplomacy.Keble College, University of OxfordUniversities’ China Committee in Londo
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