158 research outputs found

    Анализ термодинамических параметров нефтепровода с предварительным подогревом нефти в условиях Севера

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    Объектом исследования является трубопровод, на котором применяется технология перекачки нефти с предварительным подогревом. Цель работы – определить влияние термодинамических характеристик трубопроводного транспорта нефти в условиях Севера на эффективность технологии перекачки нефти с предварительным подогревом. В процессе исследования проводились гидравлические и тепловые расчеты, расчет оптимальной температуры транспорта, расчет экономической эффективности использования технологии транспорта с подогревом. Рассмотрены вопросы корректного описания вязкостно-температурной характеристики нефти для определения оптимальной температуры подогрева нефти, влияния термодинамических параметров системы «нефтепровод-окружающая среда» на эффективность применения предварительного подогрева.The object of research is the hot oil pipeline. Purpose - to determine the influence of the thermodynamic characteristics of the pipeline transport of oil in the North on the effectiveness of technology of hot oil transfer. The study carried out hydraulic and thermal calculations, the calculation of optimal transport temperature, calculation of economic efficiency of use of hot oil transport. The questions of the correct description of viscosity-temperature characteristics of the oil to determine the optimum temperature of heating oil, the effect of thermodynamic parameters of the system "pipeline-environment" on the effectiveness of transport. Presents measures for health and safety point of operation of oil heating, environmental protection, technical and economic part

    Формирование проектных команд на основе анализа социальных сетей

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    Цель исследования – разработка социальной технологии равномерного разделения сложившегося коллектива на проектные группы. В процессе исследования проводилось разделение группы, состоящей из 20 студентов, на четыре мини-группы по 5 человек для реализации проектов, ранжирование полученных мини-групп по уровню сложности выполняемых задач и статистическая оценка эффективности разделения. В результате исследования учебная группа из 20 студентов была разделена на четыре мини-группы по 5 человек с коэффициентом модулярности кластеризации 0,284, проведено ранжирование полученных мини-групп по уровню сложности выполняемых задач, статистически оценено положительное влияние взаимодействия внутри мини-групп на индивидуальную академическую успеваемость студентов.The purpose of study is a development of social technology of uniform division of the existing staff in the project groups. During the study, there were conducted division of the group consisting of 20 students into four mini-groups of 5 people for the projects' realization, ranking of received mini-groups by the level of the task complexity to perform, and statistical evaluation of the division efficiency. As a result, the group of 20 students was divided into four mini-groups of 5 people with modularity coefficient of clustering equals to 0.284, ranking of received mini-groups by the level of the task complexity to perform was conducted, positive influence of interaction within mini-groups on individual academic performance of students was statistically estimated

    High spatial resolution cardiovascular magnetic resonance at 7.0 Tesla in patients with hypertrophic cardiomyopathy - first experiences: lesson learned from 7.0 Tesla

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    BACKGROUND: Cardiovascular Magnetic Resonance (CMR) provides valuable information in patients with hypertrophic cardiomyopathy (HCM) based on myocardial tissue differentiation and the detection of small morphological details. CMR at 7.0T improves spatial resolution versus today's clinical protocols. This capability is as yet untapped in HCM patients. We aimed to examine the feasibility of CMR at 7.0T in HCM patients and to demonstrate its capability for the visualization of subtle morphological details. METHODS: We screened 131 patients with HCM. 13 patients (9 males, 56 +/-31 years) and 13 healthy age- and gender-matched subjects (9 males, 55 +/-31years) underwent CMR at 7.0T and 3.0T (Siemens, Erlangen, Germany). For the assessment of cardiac function and morphology, 2D CINE imaging was performed (voxel size at 7.0T: (1.4x1.4x2.5) mm3 and (1.4x1.4x4.0) mm3; at 3.0T: (1.8x1.8x6.0) mm3). Late gadolinium enhancement (LGE) was performed at 3.0T for detection of fibrosis. RESULTS: All scans were successful and evaluable. At 3.0T, quantification of the left ventricle (LV) showed similar results in short axis view vs. the biplane approach (LVEDV, LVESV, LVMASS, LVEF) (p = 0.286; p = 0.534; p = 0.155; p = 0.131). The LV-parameters obtained at 7.0T where in accordance with the 3.0T data (pLVEDV = 0.110; pLVESV = 0.091; pLVMASS = 0.131; pLVEF = 0.182). LGE was detectable in 12/13 (92%) of the HCM patients. High spatial resolution CINE imaging at 7.0T revealed hyperintense regions, identifying myocardial crypts in 7/13 (54%) of the HCM patients. All crypts were located in the LGE-positive regions. The crypts were not detectable at 3.0T using a clinical protocol. CONCLUSIONS: CMR at 7.0T is feasible in patients with HCM. High spatial resolution gradient echo 2D CINE imaging at 7.0T allowed the detection of subtle morphological details in regions of extended hypertrophy and LGE

    Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging

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    Cardiovascular magnetic resonance imaging is the gold standard for cardiac function assessment. Quantification of clinical results (CR) requires precise segmentation. Clinicians statistically compare CRs to ensure reproducibility. Convolutional Neural Network developers compare their results via metrics. Aim: Introducing software capable of automatic multilevel comparison. A multilevel analysis covering segmentations and CRs builds on a generic software backend. Metrics and CRs are calculated with geometric accuracy. Segmentations and CRs are connected to track errors and their effects. An interactive GUI makes the software accessible to different users. The software's multilevel comparison was tested on a use case based on cardiac function assessment. The software shows good reader agreement in CRs and segmentation metrics (Dice > 90%). Decomposing differences by cardiac position revealed excellent agreement in midventricular slices: > 90% but poorer segmentations in apical (> 71%) and basal slices (> 74%). Further decomposition by contour type locates the largest millilitre differences in the basal right cavity (> 3 ml). Visual inspection shows these differences being caused by different basal slice choices. The software illuminated reader differences on several levels. Producing spreadsheets and figures concerning metric values and CR differences was automated. A multilevel reader comparison is feasible and extendable to other cardiac structures in the future

    Global gene flow releases invasive plants from environmental constraints on genetic diversity

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    When plants establish outside their native range, their ability to adapt to the new environment is influenced by both demography and dispersal. However, the relative importance of these two factors is poorly understood. To quantify the influence of demography and dispersal on patterns of genetic diversity underlying adaptation, we used data from a globally distributed demographic research network comprising 35 native and 18 nonnative populations of Plantago lanceolata. Species-specific simulation experiments showed that dispersal would dilute demographic influences on genetic diversity at local scales. Populations in the native European range had strong spatial genetic structure associated with geographic distance and precipitation seasonality. In contrast, nonnative populations had weaker spatial genetic structure that was not associated with environmental gradients but with higher within-population genetic diversity. Our findings show that dispersal caused by repeated, long-distance, human-mediated introductions has allowed invasive plant populations to overcome environmental constraints on genetic diversity, even without strong demographic changes. The impact of invasive plants may, therefore, increase with repeated introductions, highlighting the need to constrain future introductions of species even if they already exist in an area

    Transcranial magnetic stimulation, synaptic plasticity and network oscillations

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    Transcranial magnetic stimulation (TMS) has quickly progressed from a technical curiosity to a bona-fide tool for neurological research. The impetus has been due to the promising results obtained when using TMS to uncover neural processes in normal human subjects, as well as in the treatment of intractable neurological conditions, such as stroke, chronic depression and epilepsy. The basic principle of TMS is that most neuronal axons that fall within the volume of magnetic stimulation become electrically excited, trigger action potentials and release neurotransmitter into the postsynaptic neurons. What happens afterwards remains elusive, especially in the case of repeated stimulation. Here we discuss the likelihood that certain TMS protocols produce long-term changes in cortical synapses akin to long-term potentiation and long-term depression of synaptic transmission. Beyond the synaptic effects, TMS might have consequences on other neuronal processes, such as genetic and protein regulation, and circuit-level patterns, such as network oscillations. Furthermore, TMS might have non-neuronal effects, such as changes in blood flow, which are still poorly understood

    The handbook for standardised field and laboratory measurements in terrestrial climate-change experiments and observational studies

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    Climate change is a worldwide threat to biodiversity and ecosystem structure, functioning, and services. To understand the underlying drivers and mechanisms, and to predict the consequences for nature and people, we urgently need better understanding of the direction and magnitude of climate‐change impacts across the soil–plant–atmosphere continuum. An increasing number of climate‐change studies is creating new opportunities for meaningful and high‐quality generalisations and improved process understanding. However, significant challenges exist related to data availability and/or compatibility across studies, compromising opportunities for data re‐use, synthesis, and upscaling. Many of these challenges relate to a lack of an established “best practice” for measuring key impacts and responses. This restrains our current understanding of complex processes and mechanisms in terrestrial ecosystems related to climate change

    Determination of nutrient salts by automatic methods both in seawater and brackish water: the phosphate blank

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    9 páginas, 2 tablas, 2 figurasThe main inconvenience in determining nutrients in seawater by automatic methods is simply solved: the preparation of a suitable blank which corrects the effect of the refractive index change on the recorded signal. Two procedures are proposed, one physical (a simple equation to estimate the effect) and the other chemical (removal of the dissolved phosphorus with ferric hydroxide).Support for this work came from CICYT (MAR88-0245 project) and Conselleria de Pesca de la Xunta de GaliciaPeer reviewe
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