60 research outputs found

    Modelling Word Meaning using Efficient Tensor Representations

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    Overheating in English dwellings: comparing modelled and monitored large-scale datasets

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    Monitoring and modelling studies of the indoor environment indicate that there are often discrepancies between simulation results and measurements. The availability of large monitoring datasets of domestic buildings allows for more rigorous validation of the performance of building simulation models derived from limited building information, backed by statistical significance tests and goodness-of-fit metrics. These datasets also offer the opportunity to test modelling assumptions. This paper investigates the performance of domestic housing models using EnergyPlus software to predict maximum daily indoor temperatures over the summer of 2011. Monitored maximum daily indoor temperatures from the English Housing Survey's (EHS) Energy Follow-Up Survey (EFUS) for 823 nationally representative dwellings are compared against predictions made by EnergyPlus simulations. Due to lack of information on the characteristics of individual dwellings, the models struggle to predict maximum temperatures in individual dwellings and performance was worse on days when the outdoor maximum temperatures were high. This research indicates that unknown factors such as building characteristics, occupant behaviour and local environment makes the validation of models for individual dwellings a challenging task. The models did, however, provide an improved estimate of temperature exposure when aggregated over dwellings within a particular region

    Projecting the impacts of housing on temperature-related mortality in London during typical future years

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    Climate change means the UK will experience warmer winters and hotter summers in the future. Concurrent energy efficiency improvements to housing may modify indoor exposures to heat or cold, while population aging may increase susceptibility to temperature-related mortality. We estimate heat and cold mortality and energy consumption in London for typical (non-extreme) future climates, given projected changes in population and housing. Building physics models are used to simulate summertime and wintertime indoor temperatures and space heating energy consumption of London dwellings for 'baseline' (2005-2014) and future (2030s, 2050s) periods using data from the English Housing Survey, historical weather data, and projected future weather data with temperatures representative of 'typical' years. Linking to population projections, we calculate future heat and cold attributable mortality and energy consumption with demolition, construction, and alternative scenarios of energy efficiency retrofit. At current retrofit rates, around 168-174 annual cold-related deaths per million population would typically be avoided by the 2050s, or 261-269 deaths per million under ambitious retrofit rates. Annual heat deaths would typically increase by 1 per million per year under the current retrofit rate, and 12-13 per million under ambitious rates without population adaptation to heat. During typical future summers, an estimated 38-73% of heat-related deaths can be avoided using external shutters on windows, with their effectiveness lower during hotter weather. Despite warmer winters, ambitious retrofit rates are necessary to reduce typical annual energy consumption for heating below baseline levels, assuming no improvement in heating system efficiencies. Concerns over future overheating in energy efficient housing are valid but increases in heat attributable mortality during typical and hot (but not extreme) summers are more than offset by significant reductions in cold mortality and easily mitigated using passive measures. More ambitious retrofit rates are critical to reduce energy consumption and offer co-benefits for reducing cold-related mortality

    Prevalence and pattern of brown adpose tissue distribution of 18F-FDG in patients undergoing PET-CT in a subtropical climatic zone

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    BACKGROUND The uptake of 18F-FDG in brown adipose tissue (BAT) may have important implications in understanding the pathophysiology of BAT and obesity. Because of the thermal implications of BAT uptake of 18F-FDG, this study aimed to contribute to existing knowledge by assessing patients scanned in a subtropical environment with particular reference to ethnicity. PATIENTS AND METHODS A retrospective study was carried out to determine the prevalence and pattern of BAT uptake in patients undergoing 18F-FDG PET-CT imaging in a PET facility located in a subtropical climatic zone. Standardized uptake values were obtained for regions of BAT uptake of 18F-FDG, and the distribution pattern was assessed according to anatomical region, sex, age, BMI and ethnicity. RESULTS Following a reveiw of a total of 386 scans, 38 patients showed BAT uptake of 18F-FDG (9.85%), with the mass and activity of BAT being greater in women than in men (11.95 and 6.88%, respectively). BAT uptake of 18F-FDG in the neck/supraclavicular, axillary and mediastinal regions was greater in adults whose BMI was less than 18kg/m2. However, perirenal BAT activity was shown to be greater in obese individuals. The frequency of BAT uptake of 18F-FDG was 55% in winter as against 45% during summer (P<0.012). There was no statistical difference in BAT uptake between black and white patients. CONCLUSION This study shows the pattern and prevalence of BAT in patients in a subtropical environment. Although the average seasonal temperatures are higher in a subtropical climate, a seasonal variation in BAT expression was observed, although there were no differences with respect to patient ethnicity.http://www.lww.comhb201

    The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations

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    This paper reviews current knowledge on the role of the long-chain polyunsaturated fatty acids (LC-PUFA), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, 20:4n-6), in maternal and term infant nutrition as well as infant development. Consensus recommendations and practice guidelines for health-care providers supported by the World Association of Perinatal Medicine, the Early Nutrition Academy, and the Child Health Foundation are provided. The fetus and neonate should receive LC-PUFA in amounts sufficient to support optimal visual and cognitive development. Moreover, the consumption of oils rich in n-3 LC-PUFA during pregnancy reduces the risk for early premature birth. Pregnant and lactating women should aim to achieve an average daily intake of at least 200mg DHA. For healthy term infants, we recommend and fully endorse breastfeeding, which supplies preformed LC-PUFA, as the preferred method of feeding. When breastfeeding is not possible, we recommend use of an infant formula providing DHA at levels between 0.2 and 0.5 weight percent of total fat, and with the minimum amount of AA equivalent to the contents of DHA. Dietary LC-PUFA supply should continue after the first six months of life, but currently there is not sufficient information for quantitative recommendation

    Application of an indoor air pollution metamodel to a spatially-distributed housing stock

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    Estimates of population air pollution exposure typically rely on the outdoor component only, and rarely account for populations spending the majority of their time indoors. Housing is an important modifier of air pollution exposure due to outdoor pollution infiltrating indoors, and the removal of indoor-sourced pollution through active or passive ventilation. Here, we describe the application of an indoor air pollution modelling tool to a spatially distributed housing stock model for England and Wales, developed from Energy Performance Certificate (EPC) data and containing information for approximately 11.5 million dwellings. First, we estimate indoor/outdoor (I/O) ratios and total indoor concentrations of outdoor air pollution for PM2.5 and NO2 for all EPC dwellings in London. The potential to estimate concentration from both indoor and outdoor sources is then demonstrated by modelling indoor background CO levels for England and Wales pre- and post-energy efficient adaptation, including heating, cooking, and smoking as internal sources. In London, we predict a median I/O ratio of 0.60 (99% CIs; 0.53–0.73) for outdoor PM2.5 and 0.41 (99%CIs; 0.34–0.59) for outdoor NO2; Pearson correlation analysis indicates a greater spatial modification of PM2.5 exposure by housing (ρ = 0.81) than NO2 (ρ = 0.88). For the demonstrative CO model, concentrations ranged from 0.4–9.9 ppm (99%CIs)(median = 3.0 ppm) in kitchens and 0.3–25.6 ppm (median = 6.4 ppm) in living rooms. Clusters of elevated indoor concentration are found in urban areas due to higher outdoor concentrations and smaller dwellings with reduced ventilation potential, with an estimated 17.6% increase in the number of living rooms and 63% increase in the number of kitchens exceeding recommended exposure levels following retrofit without additional ventilation. The model has the potential to rapidly calculate indoor pollution exposure across large housing stocks and estimate changes to exposure under different pollution or housing policy scenarios

    Developing Successful Breeding Programs for New Zealand Aquaculture: A Perspective on Progress and Future Genomic Opportunities

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    Over the past 40 years New Zealand (NZ) aquaculture has grown into a significant primary industry. Tonnage is small on a global scale, but the industry has built an international reputation for the supply of high quality seafood to many overseas markets. Since the early 1990s the industry has recognized the potential gains from selective breeding and the challenge has been to develop programs that can overcome biological obstacles (such as larval rearing and mortality) and operate cost-effectively on a relatively small scale while still providing significant gains in multiple traits of economic value. This paper provides an overview of the current status, and a perspective on genomic technology implementation, for the family based genetic improvement programs established for the two main species farmed in NZ: Chinook (king) salmon (Oncorhynchus tshawytscha) and GreenshellTM mussel (Perna canaliculus). These programs have provided significant benefit to the industry in which we are now developing genomic resources based on genotyping-by-sequencing to complement the breeding programs, enable evaluation of the genetic diversity and identify the potential benefits of genomic selection. This represents an opportunity to increase genetic gain and more effectively utilize the potential for within family selection
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