202 research outputs found

    Multiculturalismo e femminismo. Il multiculturalismo danneggia le donne?

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    Traduzione di Maria Chiara Pievatol

    Multiculturalismo e femminismo. Il multiculturalismo danneggia le donne?

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    Abstract not availabl

    O multiculturalismo Ă© ruim para as mulheres?

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    Resumo O artigo questiona as possibilidades de acomodação entre o feminismo e o multiculturalismo, em sua defesa dos direitos de grupos minoritĂĄrios. As abordagens multiculturalistas dedicam mais atenção às diferenças entre os grupos do que às diferenças e hierarquias internas aos grupos. AlĂ©m disso, prestam pouca atenção à esfera privada e domĂ©stica. Com isso, o fato de que as mulheres sejam oprimidas nessas culturas nĂŁo ganha relevĂąncia mediante a defesa de sua preservação. Para Okin, deve-se levar em conta a opressĂŁo interna aos grupos e o custo da preservação das culturas para a autonomia das mulheres. Palavras-chave: feminismo; multiculturalismo; opressĂŁo; direitos; minorias; esfera privada.   Abstract The article examines the possibilities of accommodating feminism and multiculturalism in their defense of the rights of minority groups. The multiculturalist approaches dedicate more attention to the differences between groups than to their internal differences and hierarchies. In addition, they pay little attention to the sphere of domestic and private life. Thus, in such approaches, the fact that women are subjected to oppression in these cultural groups looses relevance in face of the defense of the preservation of their cultures. To Okin, one should take into account the internal oppression and the cost of preserving those cultures in terms of their impact on the autonomy of women. Key words: feminism; multiculturalism; oppression; rights; minorities; private sphere

    Evaluating Ecohydrological Theories of Woody Root Distribution in the Kalahari

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    The contribution of savannas to global carbon storage is poorly understood, in part due to lack of knowledge of the amount of belowground biomass. In these ecosystems, the coexistence of woody and herbaceous life forms is often explained on the basis of belowground interactions among roots. However, the distribution of root biomass in savannas has seldom been investigated, and the dependence of root biomass on rainfall regime remains unclear, particularly for woody plants. Here we investigate patterns of belowground woody biomass along a rainfall gradient in the Kalahari of southern Africa, a region with consistent sandy soils. We test the hypotheses that (1) the root depth increases with mean annual precipitation (root optimality and plant hydrotropism hypothesis), and (2) the root-to-shoot ratio increases with decreasing mean annual rainfall (functional equilibrium hypothesis). Both hypotheses have been previously assessed for herbaceous vegetation using global root data sets. Our data do not support these hypotheses for the case of woody plants in savannas. We find that in the Kalahari, the root profiles of woody plants do not become deeper with increasing mean annual precipitation, whereas the root-to-shoot ratios decrease along a gradient of increasing aridity

    Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval

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    QT-interval (QT) prolongation is an established risk factor for ventricular tachyarrhythmia and sudden cardiac death. Previous genome-wide association studies in populations of the European descent have identified multiple genetic loci that influence QT, but few have examined these loci in ethnically diverse populations

    52 Genetic Loci Influencing Myocardial Mass.

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    BACKGROUND: Myocardial mass is a key determinant of cardiac muscle function and hypertrophy. Myocardial depolarization leading to cardiac muscle contraction is reflected by the amplitude and duration of the QRS complex on the electrocardiogram (ECG). Abnormal QRS amplitude or duration reflect changes in myocardial mass and conduction, and are associated with increased risk of heart failure and death. OBJECTIVES: This meta-analysis sought to gain insights into the genetic determinants of myocardial mass. METHODS: We carried out a genome-wide association meta-analysis of 4 QRS traits in up to 73,518 individuals of European ancestry, followed by extensive biological and functional assessment. RESULTS: We identified 52 genomic loci, of which 32 are novel, that are reliably associated with 1 or more QRS phenotypes at p < 1 × 10(-8). These loci are enriched in regions of open chromatin, histone modifications, and transcription factor binding, suggesting that they represent regions of the genome that are actively transcribed in the human heart. Pathway analyses provided evidence that these loci play a role in cardiac hypertrophy. We further highlighted 67 candidate genes at the identified loci that are preferentially expressed in cardiac tissue and associated with cardiac abnormalities in Drosophila melanogaster and Mus musculus. We validated the regulatory function of a novel variant in the SCN5A/SCN10A locus in vitro and in vivo. CONCLUSIONS: Taken together, our findings provide new insights into genes and biological pathways controlling myocardial mass and may help identify novel therapeutic targets
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