2005 California Health Interview Survey

Presents survey results on the health conditions and needs, health behaviors, and sources of medical care of adults, adolescents, and children in California. Analyzes data by demographics, income, and insurance status and highlights changes from 2003

Second-generation mobile satellite system. A conceptual design and trade-off study

In recent years, interest has grown in the mobile satellite (MSAT) system, a satellite-based communications system capable of providing integrated voice and data services to a large number of users. To explore the potential of a commercial mobile satellite system (MSS) beyond the horizon of the first generation, using technologies of the 1990's and to assist MSAT-X in directing its efforts, a conceptual design has been performed for a second-generation system to be launched around the mid-1990's. The design goal is to maximize the number of satellite channels and/or minimize the overall life-cycle cost, subject to the constraint of utilizing a commercial satellite bus with minimum modifications. To provide an optimal design, a series of trade-offs are performed, including antenna sizing, feed configurations, and interference analysis. Interference is a serious problem for MSAT and often an overlapping feed design is required to reduce interbeam interference. The trade-off studies will show that a simple non-overlapping feed is sufficient for the second-generation system, thus avoiding the need for the complicated beam-forming network that is associated with the overlapping feed designs. In addition, a system that operates at L-band, an alternative frequency band that is being considered by some for possible MSAT applications, is also presented

Pygmy Sperm Whale (Kogin breiJiceps) stranding record in Tasmania, Australia, and diet of a single specimen

This study describes the stranding record of the Pygmy Sperm Whale, Kogia breviceps, in Tasmanian waters, and the diet of a single individual. The Pygmy Sperm Whale is one of the most commonly stranded cetaceans in some parts of Australia, although it occurs infrequently in the Tasmanian stranding record, with only seven known stranding events. Dietary items were investigated from a single juvenile male Pygmy Sperm Whale stranded in southeast Tasmania. The recoverable diet consisted of approximately three kilograms of reconstructed cephalopod prey mass from at least 11 cephalopod species within nine families. Using reconstructed biomass, the most important family was Histioteuthidae (Histioteuthis atlantica and H. miranda: 29% of reconstructed biomass), followed by Ommastrephidae (unknown sp.: 27% of reconstructed biomass), Enoploteuthidae (Enoploteuthis sp): 25% of reconstructed biomass), Cranchiidae (Cranchia scabra and Teuthowenia pellucida), Chiroteuthidae (Chiroteuthis veranyi), Brachioteuthidae (Brachioteuthis linkovskyi), Neoteuthidae (Nototeuthis dimegacotyle), Pyroteuthidae (Pyroteuthis margaritifera) and Sepiolidae (Heteroteuthis sp.). Collection and analysis of biological material from Pygmy Sperm Whale strandings around Australia should be a high priority to better understand the ecology of this poorly known species

The Interactional Uses of Response Tokens in Korean Conversation: As Resources for Managing Turns, Sequences, and Stances

Ph.D

The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly

Ipl1p is the budding yeast member of the Aurora family of protein kinases, critical regulators of genomic stability that are required for chromosome segregation, the spindle checkpoint, and cytokinesis. Using time-lapse microscopy, we found that Ipl1p also has a function in mitotic spindle disassembly that is separable from its previously identified roles. Ipl1–GFP localizes to kinetochores from G1 to metaphase, transfers to the spindle after metaphase, and accumulates at the spindle midzone late in anaphase. Ipl1p kinase activity increases at anaphase, and ipl1 mutants can stabilize fragile spindles. As the spindle disassembles, Ipl1p follows the plus ends of the depolymerizing spindle microtubules. Many Ipl1p substrates colocalize with Ipl1p to the spindle midzone, identifying additional proteins that may regulate spindle disassembly. We propose that Ipl1p regulates both the kinetochore and interpolar microtubule plus ends to regulate its various mitotic functions

Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation

The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the hypothesis that a number of negative regulators of mTORC1 will be engaged during a supraphysiological model of hypertrophy. To achieve this, mTORC1- IRS-1/2 signaling, BiP/CHOP/IRE1, and AMPK activation were determined in rat plantaris muscle following synergist ablation (SA). SA resulted in significant increases in muscle mass of 4% per day throughout the 21 days of the experiment. The expression of the insulin-like growth factors (IGF) were high throughout the 21st day of overload. However, IGF signaling was limited, since IRS-1 and -2 were undetectable in the overloaded muscle from day 3 to day 9. The decreases in IRS-1/2 protein were paralleled by increases in GRB10 Ser501/503 and S6K1 Thr389 phosphorylation, two mTORC1 targets that can destabilize IRS proteins. PKB Ser473 phosphorylation was higher from 3– 6 days, and this was associated with increased TSC2 Thr939 phosphorylation. The phosphorylation of TSC2 Thr1345 (an AMPK site) was also elevated, whereas phosphorylation at the other PKB site, Thr1462, was unchanged at 6 days. In agreement with the phosphorylation of Thr1345, SA led to activation of AMPK1 during the initial growth phase, lasting the first 9 days before returning to baseline by day 12. The UPR markers CHOP and BiP were elevated over the first 12 days following ablation, whereas IRE1 levels decreased. These data suggest that during supraphysiological muscle loading at least three potential molecular brakes engage to downregulate mTORC1. m

Ceilometer based analysis of Shanghai’s boundary layer height (under rain and fog free conditions)

To investigate boundary layer dynamics of the coastal megacity Shanghai, backscatter data measured by a Vaisala CL51 ceilometer are analyzed with a modified ideal curve fitting algorithm. The boundary layer height (zi) retrieved by this method and from radiosondes compare reasonably overall. Analyses of mobile and stationary ceilometer data provide spatial and temporal characteristics of Shanghai’s boundary layer height. The consistency between when the ceilometer is moving and stationary highlights the potential of mobile observations of transects across cities. Analysis of 16 months of zi measured at FengXian in Shanghai, reveals that the diurnal variation of zi in the four seasons follows the expected pattern; for all seasons zi starts to increase at sunrise, reflecting the influence of solar radiation. However, the boundary layer height is generally higher in autumn and winter than in summer and spring (mean hourly averaged zi for days with low cloud fraction at 11:00 to 12:00 are 900 m, 654 m, 934 m and 768 m for spring, summer, autumn and winter, respectively). This is attributed to seasonal differences in the dominant meteorological conditions, including the effects of a sea breeze at the near-coastal FengXian site. Given the success of the retrieval method, other ceilometers installed across Shanghai are now being analyzed to understand more about the spatial dynamics of zi and to investigate in more detail effects of prevailing meso-scale circulations and their seasonal dynamics

Scientific mindfulness: a foundation for future themes in international business

We conceptualize new ways to qualify what themes should dominate the future IB research agenda by examining three questions: Whom should we ask? What should we ask and which selection criteria should we apply? What are the contextual forces? We propose scientific mindfulness as the way forward for generating themes in IB research