Referentes teóricos psicopedagógicos de la formación para el desarrollo de la carrera emprendedora

With the intention of defining a theoretical framework to promote a training design that motivates the professional development of entrepreneurs, the aim is to validate the theoretical referents from a practical perspective. Accordingly, this study presents a meta-analysis of literature contributions that from the perspective of 9 experts with a profile of consolidated entrepreneurs have been representative in their work activity. Specifically, a review of 107 materials contributed by these experts in the field of professional guidance for entrepreneurship was carried out. Once this material was coded and classified, it was analyzed to what extent these contributions would be recommendable for consolidated entrepreneurs, in transition or potential, using indicators intentionally selected according to structural criteria representative of the study. The proposed methodological design is mixed according to criteria and indicators of quantitative and qualitative analysis. The results establish that the greatest number of documents used come from articles of journals and databases such as ISOC, Trobes Plus and Dialnet, sources therefore of which the considered experts are nourished. At the same time, it is concluded that the largest number of outstanding documents is of an international nature whose research methodology is qualitative or mixed in nature. The meta-analysis carried out was indispensable as a bridge between research and experts in entrepreneurship, which helped to complement and validate the theoretical framework proposed, as well as to detect conceptual gaps integrating professional practice, useful in future research and understood as step sine qua non so that current scientific research has a necessary social impact.Con la intención de definir un marco teórico para promover un diseño formativo que motive el desarrollo profesional de personas emprendedoras, en este estudio se validan de los referentes teóricos psicopedagógicos de partida desde la perspectiva práctica. De acuerdo con ello, se presenta un meta-análisis de aportaciones de literatura que desde la perspectiva de 9 personas expertas con un perfil emprendedor consolidado han sido representativas en su actividad laboral. Concretamente, se llevó a cabo una revisión de 107 materiales aportados por el grupo de personas expertas en el ámbito de la orientación profesional para el emprendimiento. Una vez codificado y clasificado dicho material, se analizó en qué medida dichas contribuciones serían recomendables para personas emprendedoras consolidadas, en transición o potenciales, usando indicadores seleccionados intencionalmente según criterios estructurales representativos del estudio. El diseño metodológico planteado es mixto atendiendo a criterios e indicadores de análisis de naturaleza cuantitativa y cualitativa. Los resultados establecen que el mayor número de documentos utilizados proceden de artículos de revistas y de bases de datos como ISOC, Trobes Plus y Dialnet, fuentes por tanto de las que beben las personas expertas consideradas. Al mismo tiempo, se concluye que el mayor número de documentos destacados es de carácter internacional cuya metodología de investigación es de naturaleza cualitativa o mixta. El meta-análisis realizado fue indispensable como puente entre la investigación y el grupo de personas expertas en emprendedurismo, lo que ayudó a complementar y validar el marco teórico planteado, así como a detectar vacíos conceptuales integrando la práctica profesional, de utilidad en la investigación futura y entendido como paso sine qua non para que la investigación científica actual tenga un necesario impacto social

Theoretical Psychopedagogical References of Training for the Development of an Entrepreneurial Career

Agradecimientos: En primer lugar al Ministerio de economía y Competitividad por el financiamiento del Proyecto de Investigación Diseño de la carrera y gestión del talento emprendedor de la convocatoria de 2013, Plan Estatal 2013-2016 Excelencia, con Referencia: EDU 2013-45704-P (www.transitions.careers/).Con la intención de definir un marco teórico para promover un diseño formativo que motive el desarrollo profesional de personas emprendedoras, en este estudio se validan de los referentes teóricos psicopedagógicos de partida desde la perspectiva práctica. De acuerdo con ello, se presenta un meta-análisis de aportaciones de literatura que desde la perspectiva de 9 personas expertas con un perfil emprendedor consolidado han sido representativas en su actividad laboral. Concretamente, se llevó a cabo una revisión de 107 materiales aportados por el grupo de personas expertas en el ámbito de la orientación profesional para el emprendimiento. Una vez codificado y clasificado dicho material, se analizó en qué medida dichas contribuciones serían recomendables para personas emprendedoras consolidadas, en transición o potenciales, usando indicadores seleccionados intencionalmente según criterios estructurales representativos del estudio. El diseño metodológico planteado es mixto atendiendo a criterios e indicadores de análisis de naturaleza cuantitativa y cualitativa. Los resultados establecen que el mayor número de documentos utilizados proceden de artículos de revistas y de bases de datos como ISOC, Trobes Plus y Dialnet, fuentes por tanto de las que beben las personas expertas consideradas. Al mismo tiempo, se concluye que el mayor número de documentos destacados es de carácter internacional cuya metodología de investigación es de naturaleza cualitativa o mixta. El meta-análisis realizado fue indispensable como puente entre la investigación y el grupo de personas expertas en emprendedurismo, lo que ayudó a complementar y validar el marco teórico planteado, así como a detectar vacíos conceptuales integrando la práctica profesional, de utilidad en la investigación futura y entendido como paso sine qua non para que la investigación científica actual tenga un necesario impacto social.With the intention of defining a theoretical framework to promote a training design that motivates the professional development of entrepreneurs, the aim is to validate the theoretical referents from a practical perspective. Accordingly, this study presents a meta-analysis of literature contributions that from the perspective of 9 experts with a profile of consolidated entrepreneurs have been representative in their work activity. Specifically, a review of 107 materials contributed by these experts in the field of professional guidance for entrepreneurship was carried out. Once this material was coded and classified, it was analyzed to what extent these contributions would be recommendable for consolidated entrepreneurs, in transition or potential, using indicators intentionally selected according to structural criteria representative of the study. The proposed methodological design is mixed according to criteria and indicators of quantitative and qualitative analysis. The results establish that the greatest number of documents used come from articles of journals and databases such as ISOC, Trobes Plus and Dialnet, sources therefore of which the considered experts are nourished. At the same time, it is concluded that the largest number of outstanding documents is of an international nature whose research methodology is qualitative or mixed in nature. The meta-analysis carried out was indispensable as a bridge between research and experts in entrepreneurship, which helped to complement and validate the theoretical framework proposed, as well as to detect conceptual gaps integrating professional practice, useful in future research and understood as step sine qua non so that current scientific research has a necessary social impact

Towards a methodology for personal and career development from a systemic perspective

En este artículo presentamos una experiencia de innovación y mejora docente llevada a cabo en asignaturas de la Licenciatura en Psicopedagogía y el Grado en Pedagogía. Se utiliza una metodología con un enfoque sistémico. El objetivo es facilitar el desarrollo personal del alumnado como parte de su formación profesional.This article deals with an experience of innovation and educational improvement carried out in subjects of the Master in Psicopedagogía and the Degree in Pedagogy. A methodology is in use with a systemic approach. The aim is to facilitate the personal development of the student body as part of his vocational training

Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis

Background: Trinitrobenzenesulphonic acid (TNBS) induced rat colitis is one of the most widely used models of inflammatory bowel disease (IBD), a condition whose aetiology and pathophysiology are incompletely understood. We have characterized this model at the genomic level using a longitudinal approach. Six control rats were compared with colitic animals at 2, 5, 7 and 14 days after TNBS administration (n = 3). The Affymetrix Rat Expression Array 230 2.0 system was used. Results: TNBS-induced colitis had a profound impact on the gene expression profile, which was maximal 5 and 7 days post-induction. Most genes were affected at more than one time point. They were related to a number of biological functions, not only inflammation/immunity but also transport, metabolism, signal transduction, tissue remodeling and angiogenesis. Gene changes generally correlated with the severity of colitis. The results were successfully validated in a subset of genes by real-time PCR. Conclusion: The TNBS model of rat colitis has been described in detail at the transcriptome level. The changes observed correlate with pathophysiological disturbances such as tissue remodelling and alterations in ion transport, which are characteristic of both this model and IBD.This study was supported by the Instituto de Investigación Carlos III (PI051651, PI051625), the Spanish Junta de Andalucía (ARM/LD 43035), the Ministry of Industry, and Fundación Genoma España

Inhibidores selectivos de la monoamino oxidasa. 1. Hidracinas de formilimidazoles 1-sustitudos

Se ha preparado una serie de hidracinometilimidazoles I-sustituidos y estudiado su actividad IMAO. Los ensayos in vitro revelan que los I-arilimidazoles son inhibidores selectivos de la MAO A a bajas concentraciones.A series of hydrazinomethylimidazole I-sustituted was prepared and evaluated for their monoamine oxidase (MAO) inhibitory activity. In vitro testing revealed that the 1- arylimidazole derivatives were selectively inhibitors of MAO A at low concentrations

The role of ultrasound as a diagnostic and therapeutic tool in experimental animal models of stroke: A review

Ultrasound is a noninvasive technique that provides real-time imaging with excellent resolution, and several studies demonstrated the potential of ultrasound in acute ischemic stroke monitoring. However, only a few studies were performed using animal models, of which many showed ultrasound to be a safe and effective tool also in therapeutic applications. The full potential of ultrasound application in experimental stroke is yet to be explored to further determine the limitations of this technique and to ensure the accuracy of translational research. This review covers the current status of ultrasound applied to monitoring and treatment in experimental animal models of stroke and examines the safety, limitations, and future perspectives.This research was funded by the Carlos III Health Institute Health Care Research Fund grant number FIS PI16/01052 and cofunded by the European Regional Development Fund (ERDF)–Miguel Servet (CP15/00069, CPII20/00002 to María Gutiérrez–Fernández; CP20/00024 to Laura Otero–Ortega) and predoctoral fellowship (FI17/00188 to Mari Carmen Gómez–de Frutos, FI18/00026 to Fernando Laso–García) and the INVICTUS PLUS Spanish Network (RD16/0019/0005) of the Carlos III Health Institute (ISCIII)

Enseñanza de la función pública a través de medios audiovisuales

Memoria ID-0200. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015

INSTrumento de Apoyo infoGRAFico (InstaGRAF)

El "INSTrumento de Apoyo infoGRAFico (InstaGRAF)" es una actividad docente basada en la creación de un recurso educativo innovador en abierto y virtual que utiliza infografías y redes sociales para motivar, apoyar e incentivar el aprendizaje activo de los estudiantes aplicando de forma integradora los diferentes conocimientos teóricos impartidos en clases teóricas de los Grados de Farmacia y Nutrición Humana y Dietética durante el curso academico 2020/2021. Los resultados de la implantación de InstaGRAF durante el curso académico ponen de manifiesto que La elaboración de infografías y su difusión a través de redes sociales constituyen un método didáctico original y creativo bien aceptado y valorado por los estudiantes que les ha permitido comprender mejor los conceptos explicados en clase y ha contribuido a obtener un mejor rendimiento académico de los estudiantes participantes. La plataforma InstaGRAF podría ser una herramienta útil y sencilla con gran versatilidad que podría ser utilizada en cualquier asignatura y grado académico

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have the capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is a deficit in DC numbers and IFN-α production, which has been associated with disease severity. In this work, we described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers. Remarkably, previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+ myeloid DCs and pDCs seven months after SARS-CoV-2 infection. Moreover, the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed. These findings contribute to a better understanding of the immunological sequelae of COVID-19