UV Spectral Synthesis of Vega

We show that the UV spectrum (1280-3200 A) of the "superficially normal" A-star Vega, as observed by the IUE satellite at a resolution comparable to the star's rotational broadening width, can be fit remarkably well by a single-temperature synthetic spectrum based on LTE atmosphere models and a newly constructed UV line list. If Vega were a normal, equator-on, slow-rotating star, then its spectrum and our analysis would indicate a temperature of Teff ~ 9550 K, surface gravity of log g ~ 3.7, general surface metallicity of [m/H] ~ -0.5, and a microturbulence velocity of v(turb) ~ 2.0 km/s. Given its rapid rotation and nearly pole-on orientation, however, these parameters must be regarded as representing averages across the observed hemisphere. Modeling the complex UV line spectrum has allowed us to determine the specific surface abundances for 17 different chemical elements, including CNO, the light metals, and the iron group elements. The resultant abundance pattern agrees in general with previous results, although there is considerable scatter in the literature. Despite its peculiarities, Vega has turned out to provide a powerful test of the extent of our abilities to model the atmospheric properties of the early A-stars, particularly the detailed UV line spectrum. The value of the measurements from this pilot study will increase as this analysis is extended to more objects in the rich high-dispersion IUE data archive, including both normal and peculiar objects.Comment: To appear in the Astrophysical Journa

The Solar Heavy Element Abundances: II. Constraints from Stellar Atmospheres

Estimates of the bulk metal abundance of the Sun derived from the latest generation of model atmospheres are significantly lower than the earlier standard values. In Paper I we demonstrated that a low solar metallicity is inconsistent with helioseismology if the quoted errors in the atmospheres models (of order 0.05 dex) are correct. In this paper we undertake a critical analysis of the solar metallicity and its uncertainty from a model atmospheres perspective, focusing on CNO. We argue that the non-LTE corrections for abundances derived from atomic features are overestimated in the recent abundance studies, while systematic errors in the absolute abundances are underestimated. If we adopt the internal consistency between different indicators as a measure of goodness of fit, we obtain intermediate abundances [C/H] = 8.44 +/- 0.06, [N/H] = 7.96 +/- 0.10 and [O/H] = 8.75 +/- 0.08. The errors are too large to conclude that there is a solar abundance problem, and permit both the high and low scales. However, the center-to-limb continuum flux variations predicted in the simulations appear to be inconsistent with solar data, which would favor the traditional thermal structure and lead to high CNO abundances of (8.52, 7.96, 8.80) close to the seismic scale. We argue that further empirical tests of non-LTE corrections and the thermal structure are required for precise absolute abundances. The implications for beryllium depletion and possible sources of error in the numerical simulations are discussed.Comment: 36 pages, 4 figures, submitted Ap

The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55–92 Years): a double-blind randomized study

<p>Abstract</p> <p>Background</p> <p>Ageing is associated with a significant reduction in skeletal muscle carnosine which has been linked with a reduction in the buffering capacity of muscle and in theory, may increase the rate of fatigue during exercise. Supplementing beta-alanine has been shown to significantly increase skeletal muscle carnosine. The purpose of this study, therefore, was to examine the effects of ninety days of beta-alanine supplementation on the physical working capacity at the fatigue threshold (PWC_FT) in elderly men and women.</p> <p>Methods</p> <p>Using a double-blind placebo controlled design, twenty-six men (n = 9) and women (n = 17) (age ± SD = 72.8 ± 11.1 yrs) were randomly assigned to either beta-alanine (BA: 800 mg × 3 per day; n = 12; CarnoSyn™) or Placebo (PL; n = 14) group. Before (pre) and after (post) the supplementation period, participants performed a discontinuous cycle ergometry test to determine the PWC_FT.</p> <p>Results</p> <p>Significant increases in PWC_FT(28.6%) from pre- to post-supplementation were found for the BA treatment group (p < 0.05), but no change was observed with PL treatment. These findings suggest that ninety days of BA supplementation may increase physical working capacity by delaying the onset of neuromuscular fatigue in elderly men and women.</p> <p>Conclusion</p> <p>We suggest that BA supplementation, by improving intracellular pH control, improves muscle endurance in the elderly. This, we believe, could have importance in the prevention of falls, and the maintenance of health and independent living in elderly men and women.</p

Beta-alanine (Carnosyn™) supplementation in elderly subjects (60–80 years): effects on muscle carnosine content and physical capacity

The aim of this study was to investigate the effects of beta-alanine supplementation on exercise capacity and the muscle carnosine content in elderly subjects. Eighteen healthy elderly subjects (60–80 years, 10 female and 4 male) were randomly assigned to receive either beta-alanine (BA, n = 12) or placebo (PL, n = 6) for 12 weeks. The BA group received 3.2 g of beta-alanine per day (2 × 800 mg sustained-release Carnosyn™ tablets, given 2 times per day). The PL group received 2 × (2 × 800 mg) of a matched placebo. At baseline (PRE) and after 12 weeks (POST-12) of supplementation, assessments were made of the muscle carnosine content, anaerobic exercise capacity, muscle function, quality of life, physical activity and food intake. A significant increase in the muscle carnosine content of the gastrocnemius muscle was shown in the BA group (+85.4%) when compared with the PL group (+7.2%) (p = 0.004; ES: 1.21). The time-to-exhaustion in the constant-load submaximal test (i.e., TLIM) was significantly improved (p = 0.05; ES: 1.71) in the BA group (+36.5%) versus the PL group (+8.6%). Similarly, time-to-exhaustion in the incremental test was also significantly increased (p = 0.04; ES 1.03) following beta-alanine supplementation (+12.2%) when compared with placebo (+0.1%). Significant positive correlations were also shown between the relative change in the muscle carnosine content and the relative change in the time-to-exhaustion in the TLIM test (r = 0.62; p = 0.01) and in the incremental test (r = 0.48; p = 0.02). In summary, the current data indicate for the first time, that beta-alanine supplementation is effective in increasing the muscle carnosine content in healthy elderly subjects, with subsequent improvement in their exercise capacity

Determinants of muscle carnosine content

The main determinant of muscle carnosine (M-Carn) content is undoubtedly species, with, for example, aerobically trained female vegetarian athletes [with circa 13 mmol/kg dry muscle (dm)] having just 1/10th of that found in trained thoroughbred horses. Muscle fibre type is another key determinant, as type II fibres have a higher M-Carn or muscle histidine containing dipeptide (M-HCD) content than type I fibres. In vegetarians, M-Carn is limited by hepatic synthesis of β-alanine, whereas in omnivores this is augmented by the hydrolysis of dietary supplied HCD’s resulting in muscle levels two or more times higher. β-alanine supplementation will increase M-Carn. The same increase in M-Carn occurs with administration of an equal molar quantity of carnosine as an alternative source of β-alanine. Following the cessation of supplementation, M-Carn returns to pre-supplementation levels, with an estimated t1/2 of 5–9 weeks. Higher than normal M-Carn contents have been noted in some chronically weight-trained subjects, but it is unclear if this is due to the training per se, or secondary to changes in muscle fibre composition, an increase in β-alanine intake or even anabolic steroid use. There is no measureable loss of M-Carn with acute exercise, although exercise-induced muscle damage may result in raised plasma concentrations in equines. Animal studies indicate effects of gender and age, but human studies lack sufficient control of the effects of diet and changes in muscle fibre composition