16 research outputs found

    Private school entry to Oxbridge: how cultural capital counts in the making of elites

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    In this article we make an argument for the importance of embodied cultural capital in the generation of class advantage through private school students’ access to Oxbridge. Private schools in England continue to reproduce advantage (Variyan 2019), however, establishing exactly how students are advantaged through private schooling is not straightforward. Previous studies of educational advantage have drawn on the broad concept of cultural capital (e.g. Bathmaker, Ingram and Waller 2013; Reay, David and Ball 2005) to elucidate processes of inequality. We contend that within this space of Bourdieusian analysis of middle-class advantage there is a need for further thinking about embodied cultural capital as a specific and powerful form working at the symbolic level. By examining a bespoke intervention in a private school in England, we shed new light on how students are advantaged when applying to elite universities through processes that facilitate the cultivation of embodied cultural capital

    Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery

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    Genetic mechanisms of critical illness in COVID-19.

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    Host-mediated lung inflammation is present1, and drives mortality2, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development3. Here we report the results of the GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK intensive care units. We have identified and replicated the following new genome-wide significant associations: on chromosome 12q24.13 (rs10735079, P = 1.65 × 10-8) in a gene cluster that encodes antiviral restriction enzyme activators (OAS1, OAS2 and OAS3); on chromosome 19p13.2 (rs74956615, P = 2.3 × 10-8) near the gene that encodes tyrosine kinase 2 (TYK2); on chromosome 19p13.3 (rs2109069, P = 3.98 ×  10-12) within the gene that encodes dipeptidyl peptidase 9 (DPP9); and on chromosome 21q22.1 (rs2236757, P = 4.99 × 10-8) in the interferon receptor gene IFNAR2. We identified potential targets for repurposing of licensed medications: using Mendelian randomization, we found evidence that low expression of IFNAR2, or high expression of TYK2, are associated with life-threatening disease; and transcriptome-wide association in lung tissue revealed that high expression of the monocyte-macrophage chemotactic receptor CCR2 is associated with severe COVID-19. Our results identify robust genetic signals relating to key host antiviral defence mechanisms and mediators of inflammatory organ damage in COVID-19. Both mechanisms may be amenable to targeted treatment with existing drugs. However, large-scale randomized clinical trials will be essential before any change to clinical practice

    Teacher identity, teaching and pedagogical approaches

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    This new text for education undergraduates covers a broad range of themes from across the education sector and focuses on some key contemporary issues

    Biweekly disturbance capture and attribution: case study in western Alberta grizzly bear habitat

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    An increasing number of studies have demonstrated the impact of landscape disturbance on ecosystems. Satellite remote sensing can be used for mapping disturbances, and fusion techniques of sensors with complimentary characteristics can help to improve the spatial and temporal resolution of satellite-based mapping techniques. Classification of different disturbance types from satellite observations is difficult, yet important, especially in an ecological context as different disturbance types might have different impacts on vegetation recovery, wildlife habitats, and food resources. We demonstrate a possible approach for classifying common disturbance types by means of their spatial characteristics. First, landscape level change is characterized on a near biweekly basis through application of a data fusion model (spatial temporal adaptive algorithm for mapping reflectance change) and a number of spatial and temporal characteristics of the predicted disturbance patches are inferred. A regression tree approach is then used to classify disturbance events. Our results show that spatial and temporal disturbance characteristics can be used to classify disturbance events with an overall accuracy of 86% of the disturbed area observed. The date of disturbance was identified as the most powerful predictor of the disturbance type, together with the patch core area, patch size, and contiguity

    An approach for determining relationships between disturbance and habitat selection using bi-weekly synthetic images and telemetry data

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    Ecological studies can be limited by the mismatch in spatial-temporal scales between wildlife GPS telemetry data, collected sub-hourly, and the large-area maps used to identify disturbances, generally updated annually. Recent advancements in remote sensing, data fusion modeling, mapping, and change detection approaches offer environmental data products representing every 16-day period through the growing season. Here we highlight opportunities and challenges for integrating wildlife location data with high spatial and temporal resolution landscape disturbance data sets, availab
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