The Geology of Kansas—Arbuckle Group

Cambrian-Ordovician Arbuckle Group rocks in Kansas occur entirely in the subsurface. As is demonstrated throughout this paper, the historical and current understanding of the Arbuckle Group rocks in Kansas has in large part been dependent on petroleum-industry philosophies, practices, and trends. The widely accepted conceptual model of Arbuckle reservoirs as an unconformity play guided drilling and completion practices in which wells were drilled into the top of the Arbuckle with relatively short penetration (under 10 to 50 ft) deeper into the Arbuckle. This resulted in very little log or core data available from the Arbuckle interval. In addition, due to the early development (1917-1940) of the majority of Arbuckle reservoirs, log and geophysical data are not up to modern standards. Over the last few decades, deep penetrating wells have been drilled into the Arbuckle accompanied by full modern log suites and drill-stem tests. However, little corresponding core has been taken to calibrate the logs, and no detailed studies have been conducted to date on the more extensive, modern log data. Thus, data and detailed understanding of Arbuckle Group strata in Kansas are lacking relative to Arbuckle and age-equivalent strata from other areas in the United States, especially those where Arbuckle strata crop out. However, Arbuckle Group strata remain an important reservoir target in Kansas, and our understanding of the unit will increase with continued studies that incorporate modern data, techniques, and approaches

Red Sea Holocene carbonates; windward platform margin and lagoon near Al-Wajh, northern Saudi Arabia

Analysis of Holocene sedimentary seascape is focused on the Red Sea windward Al-Wajh platform margin, its central lagoon, and nearby isolated platforms based on data that include mapped ecological facies (habitats), water depths, grain sizes, and allochem types and abundances determined from thin sections. On this basis, a depositional model applicable to Red Sea Plio-Pleistocene and other ancient icehouse carbonate platforms is presented. The model highlights favorable reservoirs in analogous ancient systems to include coral crests and columnar framework habitats with primary porosity developed in boundstone lithologies and windward platform margins to contain considerable open pore space, including cavernous openings, of which not all should be anticipated to be occluded with marine cements and sediments. Meteoric diagenesis is expected to be minor as limited freshwater is available due to extreme aridity, but may play a role during glaciation. Most habitats have potential for secondary (enhanced) porosity resulting from dissolution of aragonite skeletons, particularly mollusk shells and calcareous coral (Scleractinia) endoskeletons. Central-lagoon habitats are expected to have the least favorable reservoir potential of environments considered because they are dominated by peloids. Central-lagoon sediment differs from other published localities, having higher peloid abundances, greater peloid distribution, and little or no association with Halimeda and quartz grains. Under the likely scenario that platform-interior sediments are completely bioturbated and comprise peloid-rich, grain-dominated fabrics, with many smaller peloids (most of them likely fecal pellets) at or near 4 mu m in size (i.e., mud fraction), it is possible that grain size will control pore size once the considered deposits are lithified. If so, platform-interior sediments will lithify as mudstones, wackestones, or very fine-grained grainstones, an outcome which might otherwise be unexpected given the abundance of coarse peloid grains. The Al-Wajh platform is compared with 15 Holocene analogs and found to be unique with respect to rift-margin type, restricted-marine circulation, in having a lagoon with high peloid content, and lack of karst. In further comparison with ancient reservoir analogs, two greenhouse and four icehouse, it compares favorably to icehouse platforms deposited in rift basins with respect to mineralogy of deposition, meter-scale cycle thicknesses, and general peloid content and distribution. It provides a snapshot as to how an icehouse platform might have nucleated and attached along an active rift margin; it is a broadly applicable carbonate analog for the Red Sea Plio-Pleistocene and similar icehouse, rift basins

Matrix-Mediated Delivery of Silver Nanoparticles for Prevention of Staphylococcus aureus and Pseudomonas aeruginosa Biofilm Formation in Chronic Rhinosinusitis.

Chronic rhinosinusitis (CRS) is a chronic health condition affecting the sinonasal cavity. CRS-associated mucosal inflammation leads to sinonasal epithelial cell death and epithelial cell barrier disruption, which may result in recurrent bacterial infections and biofilm formation. For patients who fail medical management and elect endoscopic sinus surgery for disease control, bacterial biofilm formation is particularly detrimental, as it reduces the efficacy of surgical intervention. Effective treatments that prevent biofilm formation in post-operative patients in CRS are currently limited. To address this unmet need, we report the controlled release of silver nanoparticles (AgNps) with silk-elastinlike protein-based polymers (SELPs) to prevent bacterial biofilm formation in CRS. This polymeric network is liquid at room temperature and forms a hydrogel at body temperature, and is hence, capable of conforming to the sinonasal cavity upon administration. SELP hydrogels demonstrated sustained AgNp and silver ion release for the studied period of three days, potent in vitro antibacterial activity against Pseudomonas aeruginosa (**** p < 0.0001) and Staphylococcus aureus (**** p < 0.0001), two of the most commonly virulent bacterial strains observed in patients with post-operative CRS, and high cytocompatibility with human nasal epithelial cells. Antibacterial controlled release platform shows promise for treating patients suffering from prolonged sinonasal cavity infections due to biofilms