Fundamental issues of rationalization in corporate decision-making

The paper deals with the problems of the improvement of the decision-making process that is composed of two sub-systems: preparations for making a decision and taking it. Based on the multiaspect characteristics of the essence and conditions of the decision-making process a referential model of decision-making has been proposed. The model assumes the existence of two principles that apparently may seem contradictory – the principle of rationality and the principle of creative uniqueness. Decision-making that follows this model increases the opportunities for making adequate decisions and implementing innovative enterprises which contribute to the company’s development

Evaluation of changes somatic features and motor skills of high school students from Kruszwica.

Introduction. The study of the physical development of children and youth have quite a rich tradition. Conducted observations show that standard of living is very different in different regions of the country. The purpose of physical education is not only to improve the body of a young man, but also providing it with the knowledge and skills related to physical education. The aim of this study was to assess the state of development of somatic children aged 13 - 14 years of high school in Kruszwica, determine the level of their motor skills and evaluation of somatic sexual dimorphism. And the answer: if holiday break contributed to changes somatic features and motor skills of subjects. Materials and methods. The study was conducted twice: before the summer (June) and after the summer break, and have them included 72 students (39 boys and 33 girls) aged 13 - 14 years. Physical development determined on the somatic features: height and weight, efficiency of the motor, in turn, on the basis of level of skills and mobility. Habit of body students characterized using the Rohrer index. To determine the motor of subjects used trials of the International Physical Fitness Test. Results and conclusions. Analysis of the results allows to draw the following conclusions: •After holiday break students are higher and heavier than before the holidays. •After holiday break increased motor skills of both sexes in the strength of the abdominal muscles, but only in boys increase the explosive power in the legs and improve their speed. •Boys achieved better results after holiday break than girls in testing the speed and explosive power tests of legs. •According to Mollison Index compared characteristics of somatic and motor skills before summer the most varied of agility course and body height, after holidays: the explosive power of the legs and body height. •The impact of the summer break has not affected to changes in somatic and motor skills of the young peopl

Cellular and cytokine immunoregulation in patients with chronic obstructive pulmonary disease and bronchial asthma.

BACKGROUND: Different forms of chronic airway inflammation may involve diverse pathogenic elements. In general, deficient defence response is a feature of chronic obstructive pulmonary disease (COPD), whereas distorted immunoregulatory mechanisms lead to development of asthmatic symptoms. In addition to diverse effector mechanisms, the cellular and humoral elements participating in the development of immune response may appear to be different in COPD and bronchial asthma (BA) patients. AIMS: To evaluate the immunoregulatory properties of T cells and monocytes in cultures of peripheral blood mononuclear cells (PBMC) and to determine the chosen cytokine profiles in COPD and BA patients. METHODS: The microcultures of PBMC from COPD and BA patients were assessed for the T-cell response to mitogens, saturation of interleukin (IL)-2 receptors, T-cell suppressive activity and monokine influence on lymphocyte proliferation. Concomitantly, the cytokine (IL-1beta, interleukin-1 receptor antagonist, tumour necrosis factor-alpha, IL-4, IL-6, IL-8) concentrations were determined in the serum, the broncho-alveolar lavage fluid and in the culture supernatants. RESULTS: The T-lymphocyte reactions (response to phytohaemagglutinin, IL-2 receptor saturation, suppressive activity) were lower in BA patients than in COPD patients. Reversely, the immunogenic activity of monocytes (IL-1beta versus IL-1ra production) was higher in BA patients than in COPD patients. The highest values of cytokine concentrations were found in the culture supernatants. The concentrations of tumour necrosis factor-alpha, IL-4, IL-6 and IL-8 were significantly higher and the concentration of IL-1ra was lower in BA patients than in COPD patients. CONCLUSION: The assessments of cellular immunoregulatory properties and cytokine profiles in the cultures of blood mononuclear cells may prove helpful for diagnostic and therapeutic discrimination between BA and COPD patients

Acquiring electric energy from the transport conveyor roller movement for distributed sensors network

The paper presents the concept of installation of an electricity generator and en energy store inside a roller of belt or roller conveyor. Accordingly, the use of a generator-pulley does not require any structural changes to be made to an existing conveyor. In addition, the user will be able to power distributed sensors network for monitoring the operation of the belt conveyor anywhere on its route. © 2020 Krzysztof Mazurek et al., published by Sciendo.European Regional Development Fund under the project CEBIA-Tech [CZ.1.05/2.1.00/03.0089

Genetic algorithm-based calibration of reduced order galerkin models

Low-dimensional models, allowing quick prediction of fluid behaviour, are key enablers of closed-loop flow control. Reduction of the model's dimension and inconsistency of high-fidelity data set and the reduced-order formulation lead to the decrease of accuracy. The quality of Reduced-Order Models might be improved by a calibration procedure. It leads to global optimization problem which consist in minimizing objective function like the prediction error of the model. In this paper, Reduced-Order Models of an incompressible flow around a bluff body are constructed, basing on Galerkin Projection of governing equations onto a space spanned by the most dominant eigenmodes of the Proper Orthogonal Decomposition (POD). Calibration of such models is done by adding to Galerkin System some linear and quadratic terms, which coefficients are estimated using Genetic Algorithm

Applications of 3D PCA method for extraction of mean shape and geometrical features of biological objects set

This article presents application of the Principal Component Analysis method for analysis of geometry of biological objects and computation of three dimensional anthropometric database. In this work as the biological objects the fifteen human femur bones were used. The geometry of each bone was obtained by using 3D structural light scanner. For PCA analysis all objects have to be described with the same FEM mesh. To achieve this, the modified fluid registration was used. PCA decomposes the set of 3D objects into mean geometry and individual features (empirical modes) describing deviations from mean value. In this paper the mean shape and features of real bones were presented and discussed. First Published Online: 14 Oct 201

Pierwotna nadczynność przytarczyc w ciąży — wyzwanie diagnostyczne i terapeutyczne

Hypercalcaemia during pregnancy is uncommon, and mostly associated with primary hyperparathyroidism (pHPT). If unrecognised, it poses a significant risk for the mother and the foetus. Maternal symptoms include: hyperemesis, muscle weakness, pancreatitis, nephrolithiasis, bone disease, mental status changes, and hypercalcaemic crisis. Untreated disease complicates foetal development and foetal death is a significant risk. Our case illustrates the difficulty in detecting pHPT during pregnancy, serious complications connected with severe hypercalcaemia, and difficulties in preparing the patient for surgical treatment. Our review of the medical literature did not identify any previous case of a pregnant woman with hypercalcaemic crisis (total calcium 17 mg/dL, parathyroid hormone 2302 pg/mL), acute pancreatitis caused by pHPT, and with hyperthyroidism, who had undergone a successful surgical treatment. (Endokrynol Pol 2015; 66 (3): 270–274)Hyperkalcemia w ciąży jest rzadko spotykanym zaburzeniem. Jej główną przyczyną jest pierwotna nadczynność przytarczyc (pHPT). Brak prawidłowo postawionego rozpoznania stanowi ryzyko zarówno dla matki, jaki płodu. Wśród objawów występujących u matki wymienia się wymioty, osłabienie siły mięśniowej, ostre zapalenie trzustki, kamicę nerkową, objawy kostne, zaburzenia psychiczne i przełom hiperkalcemiczny. Nieleczona hiperkalcemia może być przyczyną ograniczenia wzrostu, a także obumarcia płodu. Przedstawiony przypadek ukazuje trudności w rozpoznaniu pHPT w ciąży, poważne powikłania ciężkiej hiperkalcemii oraz trudności w przygotowaniu pacjentki do leczenia operacyjnego. W dotychczas opublikowanej literaturze według wiedzy autorów pracy nie przedstawiano przypadku ciężarnej z przełomem hiperkalcemicznym (całkowite stężenie wapnia 17 mg/dl, parathormon 2302 pg/ml), ostrym zapaleniem trzustki z towarzyszącą nadczynnością tarczycy, u której przeprowadzono skuteczne leczenie operacyjne. (Endokrynol Pol 2015; 66 (3): 270–274