Geotechnical Factors in Recent Earthquake-Induced Structural Failures in Greece

A review is made of geotechnical factors that played an important role in three recent earthquake-induced failures, two of which were deadly. The first two catastrophes concern two five-storey hotels that collapsed during the “Alkyonides earthquake” of 24 February 1981 (M=6.7) and the “Egion earthquake” of 15 June 1995 (M=6.2). The third failure is the collapse of a multi-storey factory caused by the “Athens earthquake” of 7 September 1999 (M=5.9). In the first two catastrophes, ground subsidence was estimated by two different methods and was found to be of the order of 0.13 to 0.46 m. These estimates are based on tentative assumptions that should be reviewed and possibly revised. Considerable differential settlements must have existed before the earthquake, as there were no basements that would have attenuated vertical loading and so even a moderate additional differential settlement could cause failure. In the third case, the structure was built near the edge of a steep slope of clayey soil. The co-seismic shear displacement caused the footings resting on the sliding mass to settle, thus causing severe distortions to the structure

Preloading for Large Storage Building

The properties and method of preloading a 11 m erratic deposit of soft clays and loose sands, are described. Under the preload embankment of 12 m the deposit compressed an average of 7%. Settlement developed rapidly and excess porepressure dissipated within few days, never exceeding 2.1 m of water head. After preload removal borings were performed to compare results with those obtained on the untreated site. This comparison showed that the compressibility and strength of both the clayey and sandy components improved substantially and that the subsurface became more homogeneous. The projected structure built on the improved ground has performed satisfactorily

Back Analysis of the Lower San Fernando Dam Slide Using a Multi-block Model

A multi-block sliding system model has been developed to simulate the displacement of sliding geo-masses. This model is a useful tool, especially when displacements are very large and computer codes based on the Finite Element Method cannot be applied. The paper investigates the ability of the model to predict the response of the well-documented Lower San Fernando Dam slide. The predicted movement, and deformation agreed reasonably well with that of the upper part of the slide. Yet, the lower part of the slide slid more that the model prediction. The multi-block model was applied a second time. This 2-slide approach predicts movement, and deformation in very good agreement with that measured. In addition, the time duration of motion is in general agreement with the observed

Stability of an Erratic Tailings Deposit

150 million cubic meters of erratic colliery spoils were deposited between 1971 and 1983 close to the Kardia lignite fields, in Greece. The heap finally reached satisfactorily an escalating height of 73 m. Field reconnaissance, collation of local experience and geotechnical investigations were performed during midstage of deposition. They aimed at an optimal configuration of the fill in progress, within the possibilities allowed by extensive earth moving operations. Present paper out- 1ines the approach and the methodology used to arrive at strength parameters and slope design of a highly inhomogeneous massive comprising variegated soils, marls and encaptured lignites

Pulse processing routines for neutron time-of-flight data

A pulse shape analysis framework is described, which was developed for n_TOF-Phase3, the third phase in the operation of the n_TOF facility at CERN. The most notable feature of this new framework is the adoption of generic pulse shape analysis routines, characterized by a minimal number of explicit assumptions about the nature of pulses. The aim of these routines is to be applicable to a wide variety of detectors, thus facilitating the introduction of the new detectors or types of detectors into the analysis framework. The operational details of the routines are suited to the specific requirements of particular detectors by adjusting the set of external input parameters. Pulse recognition, baseline calculation and the pulse shape fitting procedure are described. Special emphasis is put on their computational efficiency, since the most basic implementations of these conceptually simple methods are often computationally inefficient.Comment: 13 pages, 10 figures, 5 table

Information Content of Spontaneous Symmetry Breaking

We propose a measure of order in the context of nonequilibrium field theory and argue that this measure, which we call relative configurational entropy (RCE), may be used to quantify the emergence of coherent low-entropy configurations, such as time-dependent or time-independent topological and nontopological spatially-extended structures. As an illustration, we investigate the nonequilibrium dynamics of spontaneous symmetry-breaking in three spatial dimensions. In particular, we focus on a model where a real scalar field, prepared initially in a symmetric thermal state, is quenched to a broken-symmetric state. For a certain range of initial temperatures, spatially-localized, long-lived structures known as oscillons emerge in synchrony and remain until the field reaches equilibrium again. We show that the RCE correlates with the number-density of oscillons, thus offering a quantitative measure of the emergence of nonperturbative spatiotemporal patterns that can be generalized to a variety of physical systems.Comment: LaTeX, 9 pages, 5 figures, 1 tabl

Technical measures without enforcement tools: is there any sense? A methodological approach for the estimation of passive net length in small scale fisheries

Passive nets are currently among the most important fishing gears largely used along the Mediterranean coasts by the small scale fisheries sector. The fishing effort exerted by this sector is strongly correlated with net dimensions. Therefore, the use of passive nets is worldwide managed by defining net length and net drop. The EC Reg. 1967/2006 reports that the length of bottom-set and drifting nets may be also defined considering their weight or volume; however, no practical suggestions for fisheries inspectors are yet available. Consequently,  even if such technical measures are reasonable from a theoretical viewpoint, they are hardly suitable as a management tool, due to the difficulties in harbour control. The overall objective of this paper is to provide a quick methodological approach for the gross estimation of passive net length (by net type) on the basis of net volume. The final goal is to support fisheries managers with suitable advice for enforcement and control purposes. The results obtained are important for the management of the fishing effort exerted by small scale fisheries. The methodology developed in this study should be considered as a first attempt to tackle the tangled problem of net length estimation that can be easily applied in other fisheries and areas in order to improve the precision of the models developed herein

Pulse processing routines for neutron time-of-flight data

A pulse shape analysis framework is described, which was developed for n_TOF-Phase3, the third phase in the operation of the n_TOF facility at CERN. The most notable feature of this new framework is the adoption of generic pulse shape analysis routines, characterized by a minimal number of explicit assumptions about the nature of pulses. The aim of these routines is to be applicable to a wide variety of detectors, thus facilitating the introduction of the new detectors or types of detectors into the analysis framework. The operational details of the routines are suited to the specific requirements of particular detectors by adjusting the set of external input parameters. Pulse recognition, baseline calculation and the pulse shape fitting procedure are described. Special emphasis is put on their computational efficiency, since the most basic implementations of these conceptually simple methods are often computationally inefficient.Croatian Science Foundation - Project No. 168

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms

Immunoglobulin (Ig) gene rearrangements and oncogenic translocations are routinely assessed during the characterization of B cell neoplasms and stratification of patients with distinct clinical and biological features, with the assessment done using Sanger sequencing, targeted next-generation sequencing, or fluorescence in situ hybridization (FISH). Currently, a complete Ig characterization cannot be extracted from whole-genome sequencing (WGS) data due to the inherent complexity of the Ig loci. Here, we introduce IgCaller, an algorithm designed to fully characterize Ig gene rearrangements and oncogenic translocations from short-read WGS data. Using a cohort of 404 patients comprising different subtypes of B cell neoplasms, we demonstrate that IgCaller identifies both heavy and light chain rearrangements to provide additional information on their functionality, somatic mutational status, class switch recombination, and oncogenic Ig translocations. Our data thus support IgCaller to be a reliable alternative to Sanger sequencing and FISH for studying the genetic properties of the Ig loci.We are indebted to the Genomics Core Facility of the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) for the technical support, to R. Siebert and D. Huebschmann for sharing the CSR regions, and to K. Stamatopoulos, E. Vlachonikola and F. Psomopoulos for their helpful comments on the manuscript. We thank R. Eils, P. Lichter, C. von Kalle, S. Fröhling, H. Glimm, M. Zapatka, S. Wolf, K. Beck, and J. Kirchhof for infrastructure and pipeline development within DKFZ-HIPO and NCT POP. This study was supported by the Instituto de Salud Carlos III and the European Regional Development Fund “Una manera de hacer Europa” (PMP15/00007 to E.C.), the “la Caixa” Foundation (CLLEvolution-LCF/PR/HR17/52150017, Health Research 2017 Program HR17-00221 to E.C.), the National Institute of Health “Molecular Diagnosis, Prognosis, and Therapeutic Targets in Mantle Cell Lymphoma” (P01CA229100 to E.C.), and CERCA Programme/Generalitat de Catalunya. F.N. is supported by a pre-doctoral fellowship of the Ministerio de Economía y Competitividad (BES-2016-076372). F.M. is supported by the Memorial Sloan Kettering Cancer Center NCI Core Grant (P30 CA 008748). E.C. is an Academia Researcher of the “Institució Catalana de Recerca i Estudis Avançats” (ICREA) of the Generalitat de Catalunya. This work was partially developed at the Centre Esther Koplowitz (CEK, Barcelona, Spain).Peer ReviewedPostprint (published version