388 research outputs found
The impact of the COVID-19 pandemic on the learning and wellbeing of secondary school students: a survey in Southern Europe
The transition from the traditional model of learning and teaching to full online mode had to be implemented in many countries, in an extremely short time, as the 2020-2021 school year was in mid-stream. Secondary education, which includes students in the age range of 12-18, faced many challenges in this rapid change, as many research studies have shown. Researchers raise questions regarding the readiness of the secondary education community to transition to fully online learning. The pilot study reported in this paper deals with the impact of the transition to online learning on secondary schools in southern European countries. More specifically, this paper presents the results of a literature survey and an empirical survey using an online questionnaire which captured non-traceable responses from secondary schools that, voluntarily and anonymously, completed the questionnaire. The questions were mainly closed, with some open-ended questions for students to fill in. The study also aims to capture data on the socio-economic dimension, accessibility/ availability of the necessary technologies that enable online learning, as well as the families’ employment status and their ability to support students. A total of 90 students participated (62% female, 28% male) from three Mediterranean countries. The students’ perspectives as seen by the students themselves along with the difficulties and the issues they faced are compared and contrasted. This investigation offers a pedagogical and socio-technical analysis and highlights the needs for wellbeing as well as quality learning and teaching in the new social distance reality
Ontology Based Data Access in Statoil
Ontology Based Data Access (OBDA) is a prominent approach to query databases which uses an ontology to expose data in a conceptually clear manner by abstracting away from the technical schema-level details of the underlying data. The ontology is ‘connected’ to the data via mappings that allow to automatically translate queries posed over the ontology into data-level queries that can be executed by the underlying database management system. Despite a lot of attention from the research community, there are still few instances of real world industrial use of OBDA systems. In this work we present data access challenges in the data-intensive petroleum company Statoil and our experience in addressing these challenges with OBDA technology. In particular, we have developed a deployment module to create ontologies and mappings from relational databases in a semi-automatic fashion; a query processing module to perform and optimise the process of translating ontological queries into data queries and their execution over either a single DB of federated DBs; and a query formulation module to support query construction for engineers with a limited IT background. Our modules have been integrated in one OBDA system, deployed at Statoil, integrated with Statoil’s infrastructure, and evaluated with Statoil’s engineers and data
Asymmetric intergroup bullying: the enactment and maintenance of societal inequality at work
What does inequality mean for dysfunctional organizational behaviours, such as workplace bullying? This article argues that workplace bullying can be understood as a manifestation of intergroup dynamics originating beyond the organization. We introduce the construct of asymmetric intergroup bullying: the disproportionate mistreatment of members of low status groups, with the intended effect of enhancing the subordination of that group in society at large. Analysis of data from 38 interviews with public and private sector workers in Turkey depicts a pattern of asymmetric intergroup bullying, undertaken to achieve organizational and broader sociopolitical goals. Respondents reported bullying acts used to get rid of unwanted personnel, with the goal of avoiding severance pay, or of removing supporters of the former government from positions of political and economic influence. Bullying was also described as working towards the dominance of the sociocultural worldview of one political group over another. We discuss asymmetric intergroup bullying as one mechanism through which acute intergroup hierarchy in the broader society corrupts management practice and employee interactions, in turn exacerbating economic inequality along group lines
Bound state solutions of the Dirac-Rosen-Morse potential with spin and pseudospin symmetry
The energy spectra and the corresponding two- component spinor wavefunctions
of the Dirac equation for the Rosen-Morse potential with spin and pseudospin
symmetry are obtained. The wave ( state) solutions for this
problem are obtained by using the basic concept of the supersymmetric quantum
mechanics approach and function analysis (standard approach) in the
calculations. Under the spin symmetry and pseudospin symmetry, the energy
equation and the corresponding two-component spinor wavefunctions for this
potential and other special types of this potential are obtained. Extension of
this result to state is suggested.Comment: 18 page
Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease
The etiology of Behçet's disease (BD) is unknown, but widely considered an excessive T-cell mediated inflammatory response in a genetically susceptible host. Recent genome-wide association studies (GWAS) have shown limited number of novel loci-associations. The rarity and unequal distribution of the disease prevalence amongst different ethnic backgrounds have hampered the use of GWAS in cohorts of mixed ethnicity and sufficient sample size. However, novel statistical approaches have now enabled GWAS in admixed cohorts.We ran a GWAS on 336 BD cases and 5,843 controls. The cases consisted of Western Europeans, Middle Eastern and Turkish individuals. Participants from the Generation R study, a multiethnic birth cohort in Rotterdam, The Netherlands were used as controls. All samples were genotyped and data was combined. Linear regression models were corrected for population stratification using Genomic Principal Components and Linear Mixed Modelling. Meta-analysis was performed on selected results previously published.We identified SNPs associated at genome-wide significant level mapping to the 6p21.33 (HLA) region. In addition to this known signal two potential novel associations on chromosomes 6 and 18 were identified, yet with low minor allele frequencies. Extended meta-analysis reveal a GWS association with the IL12A variant rs17810546 on chromosome 3.We demonstrate that new statistical techniques enable GWAS analyses in a limited sized cohort of mixed ethnicity. After implementation, we confirmed the central role of the HLA region in the disease and identified new regions of interest. Moreover, we validated the association of a variant in the IL2A gene by meta-analysis with previous work. These findings enhance our knowledge of genetic associations and BD, and provide further justification for pursuing collective initiatives in genetic studies given the low prevalence of this and other rare diseases
Clinicopathological Profile and Surgical Treatment of Abdominal Tuberculosis: A Single Centre Experience in Northwestern Tanzania.
Abdominal tuberculosis continues to be a major public health problem worldwide and poses diagnostic and therapeutic challenges to general surgeons practicing in resource-limited countries. This study was conducted to describe the clinicopathological profile and outcome of surgical treatment of abdominal tuberculosis in our setting and compare with what is described in literature. A prospective descriptive study of patients who presented with abdominal tuberculosis was conducted at Bugando Medical Centre (BMC) in northwestern Tanzania from January 2006 to February 2012. Ethical approval to conduct the study was obtained from relevant authorities. Statistical data analysis was performed using SPSS version 17.0. Out of 256 patients enrolled in the study, males outnumbered females. The median age was 28 years (range = 16-68 years). The majority of patients (77.3%) had primary abdominal tuberculosis. A total of 127 (49.6%) patients presented with intestinal obstruction, 106 (41.4%) with peritonitis, 17 (6.6%) with abdominal masses and 6 (2.3%) patients with multiple fistulae in ano. Forty-eight (18.8%) patients were HIV positive. A total of 212 (82.8%) patients underwent surgical treatment for abdominal tuberculosis. Bands /adhesions (58.5%) were the most common operative findings. Ileo-caecal region was the most common bowel involved in 122 (57.5%) patients. Release of adhesions and bands was the most frequent surgical procedure performed in 58.5% of cases. Complication and mortality rates were 29.7% and 18.8% respectively. The overall median length of hospital stay was 32 days and was significantly longer in patients with complications (p < 0.001). Advanced age (age ≥ 65 years), co-morbid illness, late presentation, HIV positivity and CD4+ count < 200 cells/μl were statistically significantly associated with mortality (p < 0.0001). The follow up of patients were generally poor as only 37.5% of patients were available for follow up at twelve months after discharge. Abdominal tuberculosis constitutes a major public health problem in our environment and presents a diagnostic challenge requiring a high index of clinical suspicion. Early diagnosis, early anti-tuberculous therapy and surgical treatment of the associated complications are essential for survival
Exact solution of Schr\"odinger equation with q-deformed quantum potentials using Nikiforov-Uvarov method
In this paper, we present the exact solution of one dimensional Schr\"odinger
equation for Wood-Saxon plus Rosen-Morse plus symmetrical double well potential
via Nikiforov-Uvarov mathematical method. The eigenvalues and eigenfunctions of
this potential are obtained. The energy equations and the corresponding wave
function for special cases of this potential are briefly discussed. The
PT-symmetry and Hermiticity for this potential are also considered.Comment: 8 pages, no figur
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Ontology-based end-user visual query formulation: Why, what, who, how, and which?
Value creation in an organisation is a time-sensitive and data-intensive process, yet it is often delayed and bounded by the reliance on IT experts extracting data for domain experts. Hence, there is a need for providing people who are not professional developers with the flexibility to pose relatively complex and ad hoc queries in an easy and intuitive way. In this respect, visual methods for query formulation undertake the challenge of making querying independent of users’ technical skills and the knowledge of the underlying textual query language and the structure of data. An ontology is more promising than the logical schema of the underlying data for guiding users in formulating queries, since it provides a richer vocabulary closer to the users’ understanding. However, on the one hand, today the most of world’s enterprise data reside in relational databases rather than triple stores, and on the other, visual query formulation has become more compelling due to ever-increasing data size and complexity—known as Big Data. This article presents and argues for ontology-based visual query formulation for end-users; discusses its feasibility in terms of ontology-based data access, which virtualises legacy relational databases as RDF, and the dimensions of Big Data; presents key conceptual aspects and dimensions, challenges, and requirements; and reviews, categorises, and discusses notable approaches and systems
Time course of collagen peak in bile duct-ligated rats
<p>Abstract</p> <p>Background</p> <p>One of the most useful experimental fibrogenesis models is the "bile duct-ligated rats". Our aim was to investigate the quantitative hepatic collagen content by two different methods during the different stages of hepatic fibrosis in bile duct-ligated rats on a weekly basis. We questioned whether the 1-wk or 4-wk bile duct-ligated model is suitable in animal fibrogenesis trials.</p> <p>Methods</p> <p>Of the 53 male Wistar rats, 8 (Group 0) were used as a healthy control group. Bile duct ligation (BDL) had been performed in the rest. Bile duct-ligated rates were sacrificed 7 days later in group 1 (10 rats), 14 days later in group 2 (9 rats), 21 days later in group 3(9 rats) and 28 days later in group 4 (9 rats). Eight rats underwent sham-operation (Sham). Hepatic collagen measurements as well as serum levels of liver enzymes and function tests were all analysed.</p> <p>Results</p> <p>The peak level of collagen was observed biochemically and histomorphometricly at the end of third week (P < 0.001 and P < 0.05). Suprisingly, collagen levels had decreased with the course of time such as at the end of fourth week (P < 0.01 and P < 0.05).</p> <p>Conclusion</p> <p>We have shown that fibrosis in bile duct-ligated rats is transient, i.e. reverses spontaneously after 3 weeks. This contrasts any situation in patients where hepatic fibrosis is progressive and irreversible as countless studies performed by many investigators in the same animal model.</p
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