Operations and control of unmanned underwater vehicles

Operations and control of unmanned underwater vehicle systems arediscussed in terms of systems and technologies, vehicles, operational deploymentsand concepts of operation. The notions underlying the specification of single vehicleoperations are contrasted to new concepts of operation to illustrate the challengesthey pose to control engineering. New research directions are discussed in thecontext of the theories and techniques from dynamic optimization and computerscience. The overall discussion is done in the context of the activities of theUnderwater Systems and Technology Laboratory from Porto University

Suicidal ideation and associated factors among high school adolescents

OBJECTIVE: To analyze the prevalence of suicidal ideation and its associated factors in school adolescents. METHODS: Cross-sectional school-based study with 674 students from public and private schools in Teresina, Piauí, in 2016. Bivariate analysis was performed with the chi-square test and multiple analysis by the Poisson regression model to estimate prevalence ratios (PR) and 95% confidence intervals (95%CI). RESULTS: The study participants were mostly female (56.7%), black (77.4%), who lived with their parents (85%), whose mothers had schooling greater than or equal to 8 years of schooling (68.8%), with family income greater than a minimum wage (58.3%), practitioners of some religion (86.8%) and coming from public school (64.7%). The prevalence of suicidal ideation was 7.9%. Higher frequency of suicidal ideation was reported among female students (10.2%). Suicidal ideation was statistically associated with students who reported not living with their parents (adjusted PR = 2.27; 95%CI 1.26–4.10; p < 0.05) and those who reported having suffered sexual violence by other students, teachers or school staff (adjusted PR = 3.40; 95%CI 1.80–6.44; p < 0.05), among which the prevalence of suicidal ideation was more than three times that observed among those who did not mention this type of violence. CONCLUSION: The prevalence of suicidal ideation in school adolescents was associated with female students, who did not live with parents and have been victim of sexual violence at school. We recommend advising the school community and health professionals to identify signs of suicidal behavior, especially in those with suspicion or proof of the occurrence of sexual violence at school.OBJETIVO: Analisar a prevalência de ideação suicida e fatores associados em adolescentes escolares. MÉTODOS: Estudo transversal de base escolar com 674 estudantes de escolas públicas e privadas em Teresina, Piauí, em 2016. Realizou-se análise bivariada com o teste do qui-quadrado e análise múltipla pelo modelo de regressão de Poisson para estimar as razões de prevalência (RP) e intervalos de confiança de 95% (IC95%). RESULTADOS: Os participantes do estudo foram em sua maioria estudantes do sexo feminino (56,7%), negros (77,4%), que moravam com os pais (85%), cujas mães apresentavam escolaridade maior ou igual a 8 anos de estudo (68,8%), com renda familiar maior que um salário mínimo (58,3%), praticantes de alguma religião (86,8%) e procedentes de escola pública (64,7%). A prevalência de ideação suicida foi de 7,9%. Maior frequência de ideação suicida foi relatada entre estudantes do sexo feminino (10,2%). Ideação suicida foi associada estatisticamente aos alunos que referiram não residir com os pais (RP ajustada = 2,27; IC95% 1,26–4,10; p < 0,05) e àqueles que informaram ter sofrido violência sexual por outros alunos, professores ou funcionários da escola (RP ajustada = 3,40; IC95% 1,80–6,44; p < 0,05), entre os quais a prevalência de ideação suicida foi mais de três vezes a observada entre aqueles que não referiram esse tipo de violência. CONCLUSÃO: A prevalência de ideação suicida em adolescentes escolares foi associada ao sexo feminino, não residir com os pais e ter sido vítima de violência sexual na escola. Recomenda-se alertar a comunidade escolar e profissionais de saúde para identificarem sinais do comportamento suicida, em especial naqueles com suspeita ou comprovação da ocorrência de violência sexual na escola

Deposição da calda de pulverização em diferentes volumes vegetativos de Coffea arabica L.

The arrangement of branches and leaves overlap in coffee plants hinder the penetration of sprayed mixture. Therefore, to determine the volume of appropriate syrup, it is important to check the condition of the crop leafiness before application. The objective of this study was to evaluate the deposition of spraying of pesticides in coffee plantations applied on different vegetative volumes. The treatments were arranged following split plot in each growing volume (5,000; 7,500; 10,000 and 17,500 m3 ha-1). And five volumes of syrup portions (150, 300, 450, 600 and 750 L ha-1) and the subplots three positions in the coffee canopy (upper, middle and lower) with four replicates. In the four volumes vegetative studied no significant interaction (p > 0.05) between the applied volume and the different vegetative volumes. However, the vegetative volume of 5000.0 and 17500.0 m3 h-1 depositions was increased with increasing flow, which can be assigned the foliar density. There was no statistical difference (p> 0.05) between the means of deposition in different thirds (heights) in the coffee plants canopy in vegetative volumes 5000.0 m3 ha-1, 10000.0 m3 ha-1 and 17500.0 m3 h-1. However, the volume of 7500.0 m3 ha-1 showed higher deposition in the middle third from the bottom third. The deposition is higher as it increases the volume of applied syrup. In plants with reduced leaf density, there is an increase in the deposition. The deposition is largest in the middle third relative to the lower third.A disposição dos ramos e sobreposição das folhas em plantas de café dificultam a penetração da calda pulverizada. Portanto, para determinar o volume de calda adequado, é importante verificar o estado de enfolhamento da lavoura antes da aplicação. Objetivou-se com este trabalho, avaliar a deposição de caldas de pulverização em lavouras de café aplicadas em diferentes volumes vegetativos. Os tratamentos foram dispostos seguindo esquema de parcelas subdivididas em cada volume vegetativo (5.000; 7.500; 10.000 e 17.500 m3 ha-1). Sendo as parcelas cinco volumes de calda (150, 300, 450, 600 e 750 L ha-1) e as subparcelas três posições no dossel do cafeeiro (terço superior, médio e inferior) com quatro repetições. Nos quatro volumes vegetativos estudados, não ocorreu interação significativa (p>0,05) entre o volume aplicado e os diferentes volumes vegetativos. Porém, os volumes vegetativos de 5.000,0 e 17.500,0 m3 ha-1 a deposição foi crescente com aumento das vazões, o que pode ser atribuído a densidade foliar. Não foi verificada diferença estatística (p> 0,05), entre as médias de deposição nos diferentes terços (alturas) no dossel das plantas de café, nos volumes vegetativos 5.000,0 m3 ha-1, 10.000,0 m3 ha-1 e 17.500,0 m3 ha-1. Contudo, no volume de 7.500,0 m3 ha-1 houve maior deposição no terço mediano em relação ao terço inferior. A deposição é maior à medida que aumenta o volume de calda aplicado. Em plantas com menor densidade foliar, há incremento na deposição. A deposição é maior no terço mediano em relação ao terço inferior

Philosophy and theatre in the century of enlightenment: Diderot, Voltaire and Rousseau

The theatrical performance has always been a continual concern during all the history of humanity, because it performs an art where people have certain stories that arouse many feelings and insights to the spectators. It highlights the fact that the theatrical performance has special importance for philosophical reflection, especially in the characteristic illustration of the philosophy of the eighteenth century. In this context, several thinkers participated intensely of the political reality of this time, using the theatrical practice on several occasions, both for the contribution to the intellectual framework and to portray the daily life of the rising class, namely the bourgeoisie. Among these thinkers, this paper will highlight the Voltaire conceptions of representation of the aristocratic theater, establishing it as a powerful means of education; Diderot about the genesis of the drama, where art had the function of refining and instructing individuals, representing the aspirations of the bourgeoisie. Since the conception of Jean-Jacques Rousseau about the theater, unlike the two mentioned thinkers, says the educational role of the theater is illusory, as the theatrical representation only reflects the passions of their audience. Thus, it is emphasized that the Genevan thinker followed a contrary understanding to the thinkers of the period

Oral Kaposi sarcoma development is associated with HIV viral load, CD4+ count and CD4+/CD8+ ratio

Kaposi?s sarcoma (KS) is an uncommon, multifocal and angioproliferative lesion, which demonstrates a poor prognosis. The aim of the present research was to explore the association of HIV viral load, CD4+ and CD8+ counts and the CD4+/CD8+ ratio on the risk of oral Kaposi?s sarcoma (KS) development. A total of 62 patients were retrieved from March 2008 to October 2020 from the files of two oral pathology centres. Clinical, laboratory and follow-up data were retrieved from their medical files. Poisson regression was used to explore the role of history of immunosuppression and its association with oral KS development. A P-value <0.05 was considered significant. Sixty-two patients were included in the present study (32 with oral KS and 30 with no presentation of lesions anywhere on the body). Patients with oral KS presented a mean age of 32.6 years, and male patients were more affected. The hard palate (15 cases; 46.8%) was the main anatomical site affected. The lesions were mostly presented as swellings (13 cases; 40.6%) and nodules (12 cases; 37.5%). Systemic manifestations were also observed, including candidiasis (4 cases; 12.5%), bacterial infection (3 cases; 9.3%), tuberculosis (3 cases; 9.3%), herpes simplex (3 cases; 9.3%) and pneumonia (3 cases; 9.3%). A significant correlation was observed between HIV viral load, CD4+ count and the CD4+/CD8+ ratio with oral KS development. HIV viral load, CD4+ count and the CD4+/CD8+ ratio are associated with oral KS development

Estudo das relações entre estrutura e atividade de parabenos: uma aula prática

Parabens are p-hydroxybenzoic acid esters widely used as preservatives. With the aim of teaching the structure-activity relationships (SAR) knowledge in a practical form, this paper proposed a practical class to view the SAR of parabens as antimicrobial agents. Methyl, ethyl, n-propyl, isopropyl and isopentyl paraben compounds were synthesized and their respective antimicrobial activities were assessed through determination of minimum inhibitory concentrations (MIC) against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 stains. With the MIC values, it was possible to verify theircorrelation with calculated lipophilicity (ClogP). This method can be applied in practical Medicinal Chemistry classes

Toxicological, genotoxic and antioxidant potential of Pyrostegia venusta

Pyrostegia venusta is usually found in the secondary growth of the Atlantic forests, and in the Brazilian Savanna. Flowers and leaves of this plant are used in folk remedies for treating a wide variety of healthy conditions, this way is important evaluate its safety and antioxidant potential for this applications. For this, was made a ethanolic extract from its flowers and analyzed with toxicological, genotoxicity and antioxidant tests, the toxicological analysis was made by reproductive toxicity in rats and clatogenicity/aneugenicity in human lymphocytes. The genotoxicity was studied by micronucleus test mice bone marrow. The antimutagenic test in root cells of Allium cepa, the antioxidant assays used was DPPH, FRAP, Lipid Perxidation and REM, beyond of that the extract was analyzed in HPLC showing the profile of its compounds. The toxicological analysis showed that P. venusta has no negative significant effect on reproductive and cellular level. The micronucleus test in mouse bone marrow, the extract protected cells from cyclophosphamide, mutagenic compound, in a similar way. The A. cepa test showed that the extract reduced chromosomal disorders formations. The antioxidant activity of extract was significant, except in REM test. The phytochemical analysis showed the presence of flavonoids compounds. P. venusta extract does not present reproductive toxicity and genotoxic effects. However, the extract of this species showed antigenotoxic and antioxidant potential, possibly due to the different flavonoid compounds present in its extract

Being physically active leads to better recovery prognosis for people diagnosed with COVID-19: A cross-sectional study

The regular practice of physical activity helps in the prevention and control of several non-communicable diseases. However, evidence on the role of physical activity in mitigating worsening clinical outcomes in people with COVID-19 is still unclear. The aim of this study was to verify whether different levels of physical activity provide protection for clinical outcomes caused by SARS-CoV-2 infection. A cross-sectional study was conducted with 509 adults (43.8 +/- 15.71 years; 61.1% female) with a positive diagnosis of COVID-19 residing in Ribeirao Preto, Sao Paulo, Brazil. Participants were interviewed by telephone to determine the severity of the infection and the physical activity performed. Binary logistic regression was used to indicate the odds ratio (OR) of active people reporting less harmful clinical outcomes from COVID-19. Active people had a lower chance of hospitalization, fewer hospitalization days, less respiratory difficulty and needed less oxygen support. The results suggest that active people, compared to sedentary people, have a lower frequency of hospitalization, length of stay, breathing difficulty and need for oxygen support. These results corroborate the importance of public policies to promote the practice of physical activity, in order to mitigate the severity of the clinical outcomes of COVID-19.info:eu-repo/semantics/publishedVersio

1º Encontro de Física Aplicada na Tríplice Fronteira

O Programa de Pós-graduação em Física Aplicada da Universidade Federal da Integração Latino-Americana (PPGFISA/UNILA) começou suas atividades em 2016 e vem formando recursos humanos em diversas subáreas da Física (modelagem matemática, física e engenharia, astrofísica, mecânica quântica e ciência dos materiais). Agora em 2023, realizou o "1° Encontro de Física Aplicada na Tríplice Fronteira" que objetivou estreitar e consolidar laços com pesquisadoras/es da região da tríplice fronteira (Argentina-BrasilParaguai). Em três dias de evento conseguimos reunir, na UNILA, unidade PTI (Parque Tecnológico de Itaipu), em Foz do Iguaçu - Brasil, mais de 130 pessoas (estudantes de graduação e pós-graduação, técnicos, pesquisadores/as e professores/as), dos três países da região da tríplice fronteira (Argentina, Brasil e Paraguai). O evento foi organizado pelo PPGFISA/UNILA com colaboração dos técnicos da Secretaria de Apoio Científico e Tecnológico (SACT/UNILA) e dos discentes do curso de Engenharia Física da UNILA e também contou com o apoio dos docentes e discentes da Universidade Estadual do Oeste do Paraná (UNIOESTE). O alto nível do evento, demonstrado por meio de 8 palestras convidadas, 18 trabalhos de apresentação oral e 15 trabalhos em forma pôster, demonstra a demanda da nossa região da tríplice fronteira na consolidação da pesquisa científica e tecnológica e por mais eventos na área de Física Aplicada. Que venham os próximos!! Agradecemos o apoio financeiro dado pelo Instituto Latino-Americano de Ciências da Vida e da Natureza (ILACVN) da UNILA, por meio dos editais internos, à Pró-reitoria de Pesquisa e Pós-Graduação (PRPPG/UNILA), a Fundação Parque Tecnológico de Itaipu (FPTI), a Coordenação de Aperfeiçoamento de Pessoal de Ensino Superior (Capes), através do Programa de Auxílio a Pós-Graduação (PROAP/2023) e também pela parceria com o Programa de Pós-Graduação Interdisciplinar em Energia e Sustentabilidade (PPGIES/UNILA). Por último, queremos agradecer especialmente aos participantes do evento por ter contribuído com discussões frutíferas e instigantes. Esperamos que conjuntamente possamos avançar e contribuir cada vez mais na busca de soluções para sociedade com o uso da Física Aplicada.Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES Instituto Latino-americano de Ciências da Vida e da Natureza - ILACVN Parque Tecnológico Itaipu - PTI Universidade Federal da Integração Latino-Americana - UNIL

Transcriptional profiles of the human pathogenic fungus paracoccidioides brasiliensis in mycelium and yeast cells

This work was supported by MCT, CNPq, CAPES, FUB, UFG, and FUNDECT-MS. PbGenome Network: Alda Maria T. Ferreira, Alessandra Dantas, Alessandra J. Baptista, Alexandre M. Bailão, Ana Lídia Bonato, André C. Amaral, Bruno S. Daher, Camila M. Silva, Christiane S. Costa, Clayton L. Borges, Cléber O. Soares, Cristina M. Junta, Daniel A. S. Anjos, Edans F. O. Sandes, Eduardo A. Donadi, Elza T. Sakamoto-Hojo, Flábio R. Araújo, Flávia C. Albuquerque, Gina C. Oliveira, João Ricardo M. Almeida, Juliana C. Oliveira, Kláudia G. Jorge, Larissa Fernandes, Lorena S. Derengowski, Luís Artur M. Bataus, Marcus A. M. Araújo, Marcus K. Inoue, Marlene T. De-Souza, Mauro F. Almeida, Nádia S. Parachin, Nadya S. Castro, Odair P. Martins, Patrícia L. N. Costa, Paula Sandrin-Garcia, Renata B. A. Soares, Stephano S. Mello, and Viviane C. B. ReisParacoccidioides brasiliensis is the causative agent of paracoccidioidomycosis, a disease that affects 10 million individuals in Latin America. This report depicts the results of the analysis of 6,022 assembled groups from mycelium and yeast phase expressed sequence tags, covering about 80% of the estimated genome of this dimorphic, thermo-regulated fungus. The data provide a comprehensive view of the fungal metabolism, including overexpressed transcripts, stage-specific genes, and also those that are up- or down-regulated as assessed by in silico electronic subtraction and cDNA microarrays. Also, a significant differential expression pattern in mycelium and yeast cells was detected, which was confirmed by Northern blot analysis, providing insights into differential metabolic adaptations. The overall transcriptome analysis provided information about sequences related to the cell cycle, stress response, drug resistance, and signal transduction pathways of the pathogen. Novel P. brasiliensis genes have been identified, probably corresponding to proteins that should be addressed as virulence factor candidates and potential new drug targets