Resposta de um cultivar de pêssego com caroço aderente à irrigação por défice regulado

Regulated deficit irrigation (RDI) involves inducing water stress during specific fruit growth phases by irrigating at less than full evapotranspiration. The objectives of this research were to study the effects of RDI perfomed at stage II of fruit growth and postharvest, on productivity of clingstone peaches, fruit quality as well as photosynthetic rate and midday leaf water potential. The research was conducted in a commercial clingstone peach (Prunus persica L. Batch cv. A-37) orchard in Greece. Trees were irrigated by means of microsprinklers and their frequency was determined using local meteorological station data and the FAO 56 Pennman-Monteith method. Photosynthetic rate was measured by a portable infrared gas analyzer. Midday leaf water potential was measured by the pressure chamber technique. During the years 2005 and 2006, the treatment RDII with irrigation applied at growth stage II of the peach tree did not affect productivity, fresh and dry mass of fruits. RDII reduced preharvest fruit drop in comparison to the control. RDII as well as the combined treatment RDII plus RDIP with irrigation applied at postharvest, at both years reduced shoot length of the vigorous shoots inside the canopy. RDII in comparison to the control increased the soluble solids content of the fruits and the ratio soluble solids/acidity. However it did not affect fruit acidity and fruit firmness. RDII as well as RDII plus RDIP in 2006 increased 'double' fruits and fruits with open cavity in comparison to the control and RDIP. Water savings were considerable and associated with the climatic conditions of each year.A irrigação por défice regulado (RDI) envolve a indução de défice de água durante fases específicas do crescimento das frutas, irrigando a taxas menores que a evapotranspiração. Os objetivos desse estudo foram verificar os efeitos da RDI no estágio II do crescimento das frutas e no periodo pós-colheita, avaliando a produtividade de pêssegos, a qualidade dos frutos, bem como a taxa fotossintética e o potencial da água na folha. A pesquisa foi desenvolvida em um pomar comercial de pêssegos com caroço aderente (Prunus persica L. Batch cv. A-37) da Grécia. As árvores foram irrigadas por meio de microaspersores e sua frequência foi determinada por meio de dados meteorológicos obtidos em estação automática e o método FAO 56 Pennman-Monteith para determinação de evepotranspiração. A taxa de fotossíntese foi medida por analisador de gás na faixa do infravermelho. O potencial da água na folha foi medido ao meio-dia usando a técnica da câmara de pressão. Durante 2005 e 2006 o tratamento RDII com irrigação aplicada no estágio II não apresentou efeito sobre a produção, pesos seco e fresco dos frutos. RDII reduziu a queda de frutos antes da colheita, em relação ao controle. RDII, como também o tratamento combinado de RDII mais RDIP com irrigação aplicada em pós-colheita, reduziu o comprimento de ramos vigorosos dentro do dossel nos dois anos de estudo. Em comparação com o controle, RDII aumentou o conteúdo de sólidos solúveis dos frutos e a relação sólidos solúveis/acidez, mas não afetou a acidez dos frutos e a firmeza da polpa. Em 2006 RDII e RDII mais RDIP aumentaram os `frutos dobrados' e frutos com cavidade aberta, em comparação com o controle. A economia de água foi considerável e associada às condições climáticas de cada ano

Saving Motives and Intention towards Saving of Bulgarian Pomaks

This research intends to shed light on the relation between individuals' saving motives and their intention towards saving, by examining the effect of background characteristics on a sample of 400 Bulgarian Pomaks. Findings revealed that future uncertainties consist the saving motive, which positively relates to the intention towards saving, with university graduates scoring higher on the saving intention scale than other educational groups. The implications of the findings are particularly important for the financial planners and educators since they are the ones who support Bulgarian Pomaks to maintain their standard of living and be prepared for financial uncertainty through saving. Keywords: Saving Motives, Intention towards Saving, Bulgarian Pomak JEL CLassifications: D10, D14.    DOI: https://doi.org/10.32479/ijefi.963

Hernias, aortic surgery and review of the literature of incisional hernias

Ciljevi: Ispitivanje veze između incizijske hernije i operacije abdominalne aorte te općenito proučiti preporuke za prevenciju incizijske hernije. Metode: Provedena je opsežna potraga u Pub-Medu. Koristili smo sljedeće MeSH uvjete; aneurizma abdominalne aorte; incizijska hernija; ingvinalna hernija; incizijska hernija i radiologija, zatvaranje abdominalnih rana, također je korištena „snow-falling“ potraga s navedenim ključnim riječima. Rezultati: Do danas ne postoji jednoglasnost u pogledu odnosa aorte i aortoilijačne patologije te incizijske ili ingvinalne hernije, iako većina studija ukazuje na to da je moguće povećanje učestalosti incizijske hernije nakon operacije na aorti. Zaključak: Kako bismo smanjili mogućnost pojave incizijske hernije, dužina šava u odnosu da dužinu rane morala bi biti više od 4:1. Šavove treba vezati bez pretjeranog zatezivanja te za šivanje treba koristiti materijal koji upija sporo ili ne upija uopće. Koristite šav USP 2/0 na maloj igli. Kao mjesto uboda odaberite aponeurozu samo 5 do 8 mm od ruba rane, u razmaku 4 do 5 mm.Objectives: To study the relation of incisional hernias after abdominal aortic surgery and to study the recommendations for prevention of incisional hernias in general. Methods: An extensive search in Pub-Med was conducted. We used the following MeSH terms; abdominal aortic aneurysm; incisional hernia; inguinal hernia; incisional hernia and radiology, abdominal wound closure, we also did a “snow-falling” search with the above terms. Results: Still today there is not unanimity concerning the relation of aortic or aortoiliac pathology and incisional or inguinal hernias although the majority of studies suggest that there is a possible increase in the prevalence of incisional hernias after aortic surgery. Conclusions: In order to lessen the possibilities of incisional hernias suture length to wound length ration should be more that 4:1. Sutures should be tied without excessive tension and to use either a slowly absorbable or nonabsorbable suture material. Use a suture USP 2/0 mounted on a small needle. Place stitches in the aponeurosis only and 5 to 8mm from the wound edge and 4 to 5 mm apart

Tau protein is essential for stress-induced brain pathology

Exposure to chronic stress is frequently accompanied by cognitive and affective disorders in association with neurostructural adaptations. Chronic stress was previously shown to trigger Alzheimer's-like neuropathology, which is characterized by Tau hyper-phosphorylation and missorting into dendritic spines followed by memory deficits. Here, we demonstrate that stress-driven hippocampal deficits in wild-type mice are accompanied by synaptic missorting of Tau and enhanced Fyn/GluN2B-driven synaptic signaling. In contrast, mice lacking Tau [Tau knockout (Tau-KO) mice] do not exhibit stress-induced pathological behaviors and atrophy of hippocampal dendrites or deficits of hippocampal connectivity. These findings implicate Tau as an essential mediator of the adverse effects of stress on brain structure and function.We thank Dr. Peter Davies (Albert Einstein College) for the PHF1 antibody. This work was funded by Portuguese Foundation for Science & Technology (FCT) Grants PTDC/SAU-NMC/113934/2009 (to I.S.); the European Union FP7 Project SwitchBox (N.S. and O.F.X.A.); the Portuguese North Regional Operational Program (ON.2-O Novo Norte) under the National Strategic Reference Framework (QREN) through the European Regional Development Fund (FEDER); and the Education and Lifelong Learning, Supporting Postdoctoral Researchers and Large Scale Cooperative Project, cofinanced by the European Social Fund and the Greek General Secretariat for Research and Technology. J.V.-S. is a recipient of a PhD fellowship (PD/BD/105938/2014) of the University of Minho MD/PhD Program funded by the FCT

Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease

Clinical and preclinical studies firmly support the involvement of the inflammation in the pathogenesis of Alzheimer's disease (AD). Despite acetylcholinesterase inhibitors (AChEI) being widely used in AD patients, there is no conclusive evidence about their impact on the inflammatory response.Funding was received from a program co-financed by the European Social Fund and the Greek State (GSRT LS5-3808)info:eu-repo/semantics/publishedVersio

Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma

Asthma development and exacerbation is linked to respiratory virus infections. There is limited information regarding the presence of viruses during non-exacerbation/infection periods. We investigated the nasopharyngeal/nasal virome during a period of asymptomatic state, in a subset of 21 healthy and 35 asthmatic preschool children from the Predicta cohort. Using metagenomics, we described the virome ecology and the cross-species interactions within the microbiome. The virome was dominated by eukaryotic viruses, while prokaryotic viruses (bacteriophages) were independently observed with low abundance. Rhinovirus B species consistently dominated the virome in asthma. Anelloviridae were the most abundant and rich family in both health and asthma. However, their richness and alpha diversity were increased in asthma, along with the co-occurrence of different Anellovirus genera. Bacteriophages were richer and more diverse in healthy individuals. Unsupervised clustering identified three virome profiles that were correlated to asthma severity and control and were independent of treatment, suggesting a link between the respiratory virome and asthma. Finally, we observed different cross-species ecological associations in the healthy versus the asthmatic virus-bacterial interactome, and an expanded interactome of eukaryotic viruses in asthma. Upper respiratory virome "dysbiosis" appears to be a novel feature of pre-school asthma during asymptomatic/non-infectious states and merits further investigation

Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction

Emerging studies implicate Tau as an essential mediator of neuronal atrophy and cognitive impairment in Alzheimer's disease (AD), yet the factors that precipitate Tau dysfunction in AD are poorly understood. Chronic environmental stress and elevated glucocorticoids (GC), the major stress hormones, are associated with increased risk of AD and have been shown to trigger intracellular Tau accumulation and downstream Tau-dependent neuronal dysfunction. However, the mechanisms through which stress and GC disrupt Tau clearance and degradation in neurons remain unclear. Here, we demonstrate that Tau undergoes degradation via endolysosomal sorting in a pathway requiring the small GTPase Rab35 and the endosomal sorting complex required for transport (ESCRT) machinery. Furthermore, we find that GC impair Tau degradation by decreasing Rab35 levels, and that AAV-mediated expression of Rab35 in the hippocampus rescues GC-induced Tau accumulation and related neurostructural deficits. These studies indicate that the Rab35/ESCRT pathway is essential for Tau clearance and part of the mechanism through which GC precipitate brain pathology.work was supported by NIH grants R01NS080967and R21MH 104803 to C.L.W., Portuguese Foundation for Science & Technology (FCT) PhD fellowships to J. Vaz-Silva and T. Meira (PD/BD/105938/2014; PD/BD/113700/2015, respectively), and the following grants to I.S.: FCT Investigator grant IF/01799/2013, the Portuguese North Regional Operational Program (ON.2) under the National Strategic Reference Framework (QREN), through the European Regional Development Fund (FEDER), the Project Estratégico co-funded by FCT (PEst-C/SAU/LA 0026/2013) and the European Regional Development Fund COMPETE (FCOMP-01 -0124-FEDER-037298) as well as the project NORTE- 01-0145-FEDER-000013, supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER)info:eu-repo/semantics/publishedVersio

Silicon Differential Receiver With Zero-Biased Balanced Detection for Access Networks

[EN] We present an optimized differential receiver in silicon with a minimized footprint and balanced zero-biased Ge photodiodes. The receiver integrates a delay-line with a 2 ¿ 4 multimode interferometer 90° hybrid and two balanced photodiodes for differential quadrature phase-shift keying demodulation. Two receivers are tested, for 10 and 20 Gb/s operation, and well opened eye-diagrams and symbol constellations are obtained with error vector magnitude values as low as 12.5% and 19.57%, respectively. The results confirm the potential of integrated silicon receivers to become key building blocks for future passive optical access networks based on advanced modulation formats. © 1989-2012 IEEE.This work was supported in part by the European Community’s Seventh Framework Program under Grant 224312 HELIOS.Aamer, M.; Sotiropoulos, N.; Brimont, ACJ.; Fedeli, J.; Marris-Morini, D.; Cassan, E.; Vivien, L.... (2013). Silicon Differential Receiver With Zero-Biased Balanced Detection for Access Networks. IEEE Photonics Technology Letters. 25(13):1207-1210. https://doi.org/10.1109/LPT.2013.2262931S12071210251