977 research outputs found
Changing Power Dynamics among Researchers, Local Governments, and Community Members: A Community Engagement and Racial Equity Guidebook
Increasingly, local governments seek to partner with research institutions to understand and undo their legacy of racist policymaking and other aspects of structural racism. This legacy includes historical and current policies, programs, and institutional practices that have facilitated white families' social and economic upward mobility and well-being while creating systemic barriers to the mobility and well-being of families of color.This toolkit highlights community-based approaches that can catalyze equitable public policy, programs, and investments by centering a community's expertise. Our aim is to equip local government agencies and their research partners with the tools needed to transform practices, structures, and systems by joining the highly collaborative processes of racial equity and community engagement. The toolkit is designed for local governments but also for researchers and policy experts who partner with local governments
Wealth Opportunities Realized Through Homeownership (WORTH): Baseline Report
This report is part of an evaluation of the Wealth Opportunities Realized through Homeownership (WORTH) initiative. Led by the Wells Fargo Foundation, WORTH supports efforts to close persistent disparities in homeownership in Atlanta, Houston, Milwaukee, New York, Philadelphia, Richmond, San Diego, and rural and tribal areas. In each market, we examine housing supply and demand, homebuying activity, homeownership trends, and preservation conditions. We found that in almost every market, white households have higher homeownership rates than every other racial or ethnic group. Moreover, macroeconomic forces driving market conditions, like higher interest rates and moderating house prices, can significantly dampen or thwart market collaboratives' efforts to boost homeownership rates for people of color. Future evaluation will examine the implementation processes used in each market. The larger body of work contributes to understanding the crucial connection between homeownership and wealth-building and the multitude of barriers that households of color face in achieving homeownership. It also supports research-backed strategies for increasing homeownership for households of color and for reducing racial disparities
Teknik Tekstil Endüstrileri: Nonwoven Kumaş Örneği Ve Gaziantep’in Durumu
"Teknik tekstiller" kavramı ilk ortaya çıktığında sadece endüstriyel amaçlı (giysi ve ev tekstili dışında) tekstil malzemeleri için kullanılan bir ifade iken şu an geniş bir sektörü temsil eden bir kavrama dönüşmüştür. 130 milyar $'lık bir piyasa ve yüksek bir katma değer ile birçok ülke ve yatırımcının tercih ettiği bir sektör haline gelmiştir. Yıllar geçtikçe, teknolojinin de gelişimiyle, teknik tekstil üretiminde ve uygulama alanlarında büyük çapta artma olmuş; çok farklı özelliklere sahip lifler üretilmeye başlanmıştır. Teknik tekstiller, önceleri askeri ve sportif giysilerde kullanılmış; sonraları moda tasarımcılarının bu malzemeleri koleksiyonlarına taşımalarıyla, yüksek teknolojik tekstiller, günlük giysilere de adapte edilmeye başlanmıştır. 90'lı yıllardan sonra elektronik ürünlerin giysilerimize entegre edilmesiyle birlikte teknik tekstil üretimi yeni bir boyut kazanmıştır. Endüstriyel tekstil malzemesi üreticileri, moda tasarımcıları, tekstil sanatçıları ve bilim adamlarına kadar alanında uzman birçok kişinin katılımıyla teknik/akıllı malzemeler alanında yeni ürünler ortaya konmaktadır. Bu çalışmada, teknik tekstil piyasasının genişliği ve üretim açısından önde yer alan ülkelerdeki durumunun ne aşamada olduğu, gelecekte piyasanın ulaşacağı seviye ve ülkemizdeki durum hakkında veriler bir araya getirilerek sektörün genel bir bakış açısı ile değerlendirme imkânı sunmaya çalışılmıştır. İlk olarak teknik tekstil kavramları açıklanmış, daha sonra teknik tekstil sınıflamaları üzerinde durulmuştur. Dünya genelinde trend bir sektör haline gelen bu alanda genel durum ve ülkemizin durumu ortaya konmaya çalışılmış, iktisadi açıdan piyasa yapısı analiz edilmeye çalışılmış, yoğunlaşma ve Herfindal ve Hirschman endeksleri uygulanarak sektör yapısı hakkında daha net veriler ortaya konmuştur. Gaziantep'teki firmalar üzerinde yapılan bu endüstri yapısı değerlendirmesinden sonra firmaların mevcut durumlarını değerlendirmek için Swot analizi yapılmıştır
Variability and correlations of traits related to seedling vigor in two natural populations of Pappophorum vaginatum Buckley
Se evaluó variabilidad y correlación fenotípica en caracteres vinculados con el vigor de plántula en dos poblaciones de P. vaginatum. Se pesaron y embraron individualmente
100 cariopses por población ("A"; "B"). A los 43 días se determinó: longitud aérea (LA), radical (LR), total (LT) y de raíz adventicia más larga (Ladv); número de raíces adventicias (n°adv), hojas (n°hoj), hojas senescentes (n°sen) y macollos (n°mac) y peso seco aéreo (PSA) y radical (PSR). Se calculó peso seco total (PST), PSA/PSR y LA/LR. La variabilidad se analizó mediante estadística descriptiva y prueba de t. Se analizó correlación entre caracteres y regresión múltiple de los caracteres sobre PST. Las poblaciones no difirieron en PST (p≥0,05). "A" presentó mayor (p≤0,01) PSA/ PSR, LA/ LR y LA. "B" tuvo mayor (p≤0,05) LR, Ladv y PSR. Ambas poblaciones presentaron correlación significativa y positiva del PST con LA, LT, Ladv, n°adv, n°hoj y n°mac. La regresión fue significativa (p≤0,01). La variabilidad encontrada dentro y entre las poblaciones implica expectativas de respuesta a la selección. PST varió sólo dentro de poblaciones sugiriendo la conveniencia de selección intrapoblacional. La asociación encontrada entre los caracteres LA y n°mac y el vigor de plántula, debería ser considerada en la mejora genética de la implantación.It was evaluated variability and phenotypic correlation in traits related to seedling vigor in two natural populations of P.vaginatum. They were weighted and sowed individually 100 caryopses of each population ("A"; "B"). After 43 days it was determined: lenghts aerial (LA), root (LR), total (LT) and longest adventitious root (Ladv), number of adventitious root (n°adv), of leaves (n°hoj), of senescent leaves (n°sen) and of tillers (n°mac) and dry weight aerial (PSA) and root (PSR). It was calculated total dry weight (PST), PSA/PSR and LA/LR. Variability was analyzed by means of descriptive statistic and t test. It was analyzed correlation among traits and multiple regression of traits on PST. Populations did not differ in PST (p≥0.05). "A" had greater (p≤0.01) PSA/PSR, LA/LR and LA. "B" had higher (p≤0.05) LR, Ladv and PSR. Both populations showed significant and positive correlation of PST with LA, LT, Ladv, n°adv, n°hoj y n°mac. The regression was significant (p≤0.01). The variability found within and between populations implies expectations of response to selection. PST varied only within populations suggesting the convenience of intrapopulation selection. The association found between the traits LA and n°mac and the seedling vigor, should be considered for the genetic improvement of the implantation.Fil: Entio, Lisandro Jose. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; ArgentinaFil: Mujica, Maria de la Merced. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales; ArgentinaFil: Busso, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Torres, Yanina Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Montenegro, Oscar Alberto. Provincia de Buenos Aires. Ministerio de Asuntos Agrarios; ArgentinaFil: Ithurrart, Leticia Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Giorgetti, Hugo Dosindo. Provincia de Buenos Aires. Ministerio de Asuntos Agrarios; ArgentinaFil: Rodriguez, Gustavo Dionisio. Provincia de Buenos Aires. Ministerio de Asuntos Agrarios; ArgentinaFil: Bentivegna, Diego Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Brevedan, Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Fernandez, Osvaldo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Baioni, Sandra Sonia. Universidad Nacional del Sur. Departamento de Agronomía; ArgentinaFil: Fioretti, Maria Nelida. Universidad Nacional del Sur. Departamento de Agronomía; ArgentinaFil: Tucat, Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; Argentin
Efecto fitotóxico de Baccharis ulicina sobre la germinación y crecimiento inicial de Avena sativa, Lolium perenne y Raphanus sativus
Baccharis ulicina es una maleza ampliamente distribuida en los pastizales de la zona semiárida argentina. A fin de evaluar sus posibles efectos alelopáticos, se utilizaron extractos acuosos de B. ulicina (hoja, tallo, raíz y planta entera) a dos concentraciones (50 y 150 g tejido/L agua) sobre la germinación y crecimiento inicial de Avena sativa , Lolium perenne y Raphanus sativus . Para cada especie se regaron 100 semillas y se mantuvieron a 25°C y oscuridad. Se registraron la germinación de las semillas y la longitud de coleóptilo / hipocótile (C/H) y radícula (R). Con los datos obtenidos se determinó: porcentaje de germinación, coeficiente de velocidad de germinación, vigor de la germinación, inhibición de la germinación, inhibición de la longitud de la radícula y del coleóptilo / hipocótile e índice de vigor de radícula y de coleóptilo / hipocótile. Los extractos con alta concentración redujeron la germinación en promedio 65% mientras que inhibieron la longitud en 58,8% (C/H) y 93,3% (R) para A. sativa , 71,5% (C/H) y 87,9% (R) para L. perenne , y 93,8% (C/H) y 94,5% (R) para R. sativus . Se registró un evidente efecto fitotóxico de B. ulicina sobre las especies evaluadas, indicando que la alelopatía sería una estrategia ecológica de la especie.Baccharis ulicina is a weed widely distributed in pastures of the semiarid zone of Argentina. With the aim of evaluate potential allelopathic effects, aqueous extracts of B. ulicina (leaf, stem, root and whole plant) at two concentrations (50 and 150 g tissue/L water) were used on germination and initial growth of Avena sativa, Lolium perenne and Raphanus sativus. For each species, 100 seeds were watered and maintained at 25°C at darkness. Seed germination and length of coleoptile / hypocotyl (C/H) and radicle (R) was measured. Then, germination percentage, germination rate coefficient, germination vigor, inhibition of germination, inhibition of radicle length and coleoptile / hypocotyl length, radicle vigor index and the coleoptile / hypocotyl vigor index were calculated. High concentration extracts reduced germination an average of 65%, in addition, they produced a length inhibition of 58.8% (C/H) and 93.3% (R) to A. sativa, 71.5% (C/H) and 87.9% (R) to L. perenne, and 93.8% (C/H) and 94.5% (R) to R. sativus. There was an evident phytotoxic effect of B. ulicina on evaluated species, indicating that allelopathy would be an ecological strategy of the species.Fil: Tucat, Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Bentivegna, Diego Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Fernandez, Osvaldo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Busso, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Brevedan, Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Mujica, Maria de la Merced. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Departamento de Ambiente y Recursos Naturales. Cat.introduccion de Mejoramiento Genético; Argentina;Fil: Torres, Yanina Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Daddario, Juan Facundo Fabian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Conicet - Bahia Blanca. Centro Rec.nat.renovables de Zona Semiarida(i); Argentina;Fil: Ithurrart, Leticia Soledad. Universidad Nacional del Sur; Argentina;Fil: Giorgetti, Hugo Dosindo. Provincia de Buenos Aires. Ministerio de Asuntos Agrarios. Chacra Experimental de Patagones; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina;Fil: Rodriguez, Gustavo Dionisio. Provincia de Buenos Aires. Ministerio de Asuntos Agrarios. Chacra Experimental de Patagones; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina;Fil: Montenegro, Oscar Alberto. Provincia de Buenos Aires. Ministerio de Asuntos Agrarios. Chacra Experimental de Patagones; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina;Fil: Baioni, Sandra Sonia. Universidad Nacional del Sur; Argentina;Fil: Entio, Lisandro Jose. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Departamento de Ambiente y Recursos Naturales. Cat.introduccion de Mejoramiento Genético; Argentina;Fil: Fioretti, Maria Nelida. Universidad Nacional del Sur; Argentina
Safety and efficacy of ribociclib plus letrozole in patients with HR+, HER2– advanced breast cancer: Results from the Spanish sub-population of the phase 3b CompLEEment-1 trial
Background: Breast cancer is the most common malignancy and the second leading cause of cancer-related mortality in Spanish women. Ribociclib in combination with endocrine therapy (ET) has shown superiority in prolonging survival in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC) vs. ET alone.Methods: CompLEEment-1 is a single-arm, open-label phase 3b trial evaluating ribociclib plus letrozole in a broad population of patients with HR+, HER2- ABC. The primary endpoints were safety and tolerability. Here we report data for Spanish patients enrolled in CompLEEment-1.Results: A total of 526 patients were evaluated (median follow-up: 26.97 months). Baseline characteristics showed a diverse population with a median age of 54 years. At study entry, 56.5% of patients had visceral metastases and 8.7% had received prior chemotherapy for advanced disease. Rates of all-grade and Grade >= 3 adverse events (AEs) were 99.0% and 76.2%, respectively; 21.3% of patients experienced a serious AE, and 15.8% of AEs led to treatment discontinuation. AEs of special interest of neutropenia, increased alanine aminotransferase, increased aspartate aminotransferase and QTcF prolongation occurred in 77.8%, 14.8%, 11.4% and 4.0% of patients, respectively. Patients aged >70 years experienced increased rates of all-grade and Grade >= 3 neutropenia and anemia. Efficacy results were consistent with the global study.Conclusions: Results from Spanish patients enrolled in CompLEEment-1 are consistent with global data showing efficacy and a manageable safety profile for ribociclib plus letrozole treatment in patients with HR+, HER2-ABC, including populations of interest (NCT02941926).Trial registration: ClinicalTrials.gov NCT0294192
Effectiveness of rotavirus vaccination in Spain
With the aim of determining rotavirus vaccine effectiveness (RVVE) in Spain, from Oct-2008/Jun-2009, 467 consecutive children below 2 years old with acute gastroenteritis (AGE) were recruited using a pediatric research network (ReGALIP-www.regalip.org) that includes primary, emergency and hospital care settings. Of 467 enrolled children, 32.3% were rotavirus positive and 35.0% had received at least one dose of any rotavirus vaccine. RRVE to prevent any episode of rotavirus AGE was 91.5% (95% CI: 83.7%-95.6%). RVVE to prevent hospitalization by rotavirus AGE was 95.6% (85.6-98.6%). No differences in RVVE were found regarding the vaccine used. Rotavirus vaccines have showed an outstanding effectiveness in Spain
Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: Novel insights into diverse MAPK outcomes
Cellular characterisation of Candida tropicalis presenting fluconazole-related trailing growth
Women in (Dis)placement: The Field of Studies on Migrations, Social Remittances, Care and Gender in Chile
This article presents current perspectives on the gender approach to the study of migration in Chile between 1990 and 2018, contextualizing it in light of international debates in the social sciences. We will discuss how the feminization and the growth of Latin American migrations have given rise to a prolific field of research, as exemplified by studies conducted in central and northern Chile. We will show how the concepts of social remittances and caregiving permeate the Chilean debate on migrant women. We conclude with reflections on topics and perspectives to be incorporated into the Chilean research agenda on gender and migration.Se presenta un estado del arte sobre el enfoque de género en los estudios de la migración en Chile entre 1990 y 2018, contextualizándolo a la luz de debates internacionales de las ciencias sociales. Abordaremos cómo la feminización y el incremento de las migraciones latinoamericanas inauguran un prolijo campo de investigaciones, articulado a través de estudios desarrollados en el centro y en el norte de Chile. Señalaremos cómo los conceptos de remesas sociales y cuidados permean el debate chileno sobre las mujeres migrantes. Finalizamos con reflexiones sobre temas y perspectivas a ser incorporados en la agenda chilena de investigaciones sobre género y migración.The authors would like to thank the Chilean National Commission for Scientific and Technological Research (CONICYT) for funding the study that led to this article through Fondecyt Regular Project number 1160683: “Ser Mujer Mayor en Santiago. Organización social de los cuidados, feminización del envejecimiento y desigualdades acumuladas” (“Being an older woman in Santiago. Social organization of care, feminization of ageing and accumulated inequalities”), led by Herminia Gonzálvez Torralbo and Fondecyt Regular Project number 1190056: “The Boundaries of Gender Violence: Migrant Women’s Experiences in South American Border Territories” led by Menara Lube Guizardi
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