384 research outputs found
Friedrich Sieburg, a twentieth-century German francophile
Friedrich Sieburg achieved renown as a German literary critic in the years following World War II. His career in journalism and diplomacy prior to 1945, largely ignored in the 1950s and 1960s, has come under a new scrutiny since 1980. The connection between Sieburg\u27s writings, many of which dealt with France, and his work with the German Foreign Office in wartime Paris has been a particular object of this scrutiny. The study Friedrich Sieburg. A Twentieth-Century German Francophile builds on the work of Joachim Fest, Margot Taureck and others, and argues that Sieburg was a romantic nationalist who became a National Socialist. He constructed a theory, from elements in the German literary tradition, which posited French form in opposition to German mass. This theory makes intelligible his praise of the German 1933 as a national awakening and as the workings of a mythic destiny. Journalism and diplomacy served Sieburg\u27s historic role as national publicist. After 1945, Sieburg was generally silent about the Hitler regime; his was a common response in a nation unwilling to assess its past. Attached to this study is a translation of the greater part of the memoir of Paris, Our Most Beautiful Years, which Sieburg published in 1950
Venous Thromboembolism Within Professional American Sport Leagues.
Background: Numerous reports have described players in professional American sports leagues who have been sidelined with a deep vein thrombosis (DVT) or a pulmonary embolism (PE), but little is known about the clinical implications of these events in professional athletes.
Purpose: To conduct a retrospective review of injury reports from the National Hockey League (NHL), Major League Baseball (MLB), the National Basketball Association (NBA), and the National Football League (NFL) to take a closer look at the incidence of DVT/PE, current treatment approaches, and estimated time to return to play in professional athletes.
Study Design: Descriptive epidemiology study.
Methods: An online search of all team injury and media reports of DVT/PE in NHL, MLB, NBA, and NFL players available for public record was conducted by use of Google, PubMed, and SPORTDiscus. Searches were conducted using the professional team name combined with blood clot, pulmonary embolism, and deep vein thrombosis.
Results: A total of 55 venous thromboembolism (VTE) events were identified from 1999 through 2016 (NHL, n = 22; MLB, n = 16; NFL, n = 12; NBA, n = 5). Nineteen athletes were reported to have an upper extremity DVT, 15 had a lower extremity DVT, 15 had a PE, and 6 had DVT with PE. Six athletes sustained more than 1 VTE. The mean age at time of VTE was 29.3 years (range, 19-42 years). Mean (±SD) time lost from play was 6.7 ± 4.9 months (range, 3 days to career end). Seven athletes did not return to play. Players with upper extremity DVT had a faster return to play (mean ± SD, 4.3 ± 2.7 months) than those with lower extremity DVT (5.9 ± 3.8 months), PE (10.8 ± 6.8 months), or DVT with PE (8.2 ± 2.6 months) (F = 5.69, P = .002). No significant difference was found regarding time of return to play between sports.
Conclusion: VTE in professional athletes led to an average of 6.7 months lost from play. The majority of athletes were able to return to play after a period of anticoagulation or surgery. Those with an upper extremity DVT returned to play faster than those with other types of VTE. Further study is needed to look into modifiable risk factors for these events and to establish treatment and return-to-play guidelines to ensure the safety of these athletes
Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas.
BackgroundThe goal of this study was to theoretically investigate the feasibility of intraductal and transgastric approaches to ultrasound-based thermal therapy of pancreatic tumors, and to evaluate possible treatment strategies.MethodsThis study considered ultrasound applicators with 1.2 mm outer diameter tubular transducers, which are inserted into the tissue to be treated by an endoscopic approach, either via insertion through the gastric wall (transgastric) or within the pancreatic duct lumen (intraductal). 8 patient-specific, 3D, transient, biothermal and acoustic finite element models were generated to model hyperthermia (n = 2) and ablation (n = 6), using sectored (210°-270°, n = 4) and 360° (n = 4) transducers for treatment of 3.3-17.0 cm3 tumors in the head (n = 5), body (n = 2), and tail (n = 1) of the pancreas. A parametric study was performed to determine appropriate treatment parameters as a function of tissue attenuation, blood perfusion rates, and distance to sensitive anatomy.ResultsParametric studies indicated that pancreatic tumors up to 2.5 or 2.7 cm diameter can be ablated within 10 min with the transgastric and intraductal approaches, respectively. Patient-specific simulations demonstrated that 67.1-83.3% of the volumes of four sample 3.3-11.4 cm3 tumors could be ablated within 3-10 min using transgastric or intraductal approaches. 55.3-60.0% of the volume of a large 17.0 cm3 tumor could be ablated using multiple applicator positions within 20-30 min with either transgastric or intraductal approaches. 89.9-94.7% of the volume of two 4.4-11.4 cm3 tumors could be treated with intraductal hyperthermia. Sectored applicators are effective in directing acoustic output away from and preserving sensitive structures. When acoustic energy is directed towards sensitive structures, applicators should be placed at least 13.9-14.8 mm from major vessels like the aorta, 9.4-12.0 mm from other vessels, depending on the vessel size and flow rate, and 14 mm from the duodenum.ConclusionsThis study demonstrated the feasibility of generating shaped or conformal ablative or hyperthermic temperature distributions within pancreatic tumors using transgastric or intraductal ultrasound
Evaluation of Rotator Cuff Repair with Concomitant Biceps Tenodesis
Introduction: Surgical rotator cuff repair (RCR) has proven to be an effective treatment for rotator cuff tears. Commonly, rotator cuff tears are associated with concomitant biceps pathology, which are often treated by biceps tenodesis (BT). We hypothesize that patient outcomes will be similar in those that have undergone RCR with concomitant BT and isolated RCR.
Methods: This is a retrospective cohort study comparing patients who underwent arthroscopic RCR with arthroscopic or open BT to patients who underwent isolated RCR at a multisurgeon orthopaedic practice during the time period of November 2016 to December 2016. The outcome for comparison is the American Shoulder and Elbow Surgeons score (ASES). Patients with postoperative scores of at least 6 months after surgery were included. The data was collected from the Rothman Institute registry and OBERD. It was analyzed via independent t-test.
Results: A total of 53 patients (37 = M; 16 = F) were in the isolated RCR group and 34 patients (27 = M; 7 = F) were in the RCR with BT group. The average age in the isolated RCR group was 58.6 years vs. 58.9 years in the RCR with BT group. There was no statistical difference between postoperative ASES scores (83.69 and 79.43, P = .40) and difference in preoperative and postoperative ASES scores (34.26 and 35.30, P = .85) in the isolated RCR and RCR with BT groups, respectively.
Conclusion: There was no significant difference in postoperative ASES scores as well as difference in preoperative and postoperative ASES scores in patients undergoing isolated RCR and RCR with BT. This supports the hypothesis that patients undergoing RCR with BT will have similar outcomes to those undergoing isolated RCR
Nitrate and nitrite variability at the seafloor of an oxygen minimum zone revealed by a novel microfluidic in-situ chemical sensor
Microfluidics, or lab-on-a-chip (LOC) is a promising technology that allows the development of miniaturized chemical sensors. In contrast to the surging interest in biomedical sciences, the utilization of LOC sensors in aquatic sciences is still in infancy but a wider use of such sensors could mitigate the undersampling problem of ocean biogeochemical processes. Here we describe the first underwater test of a novel LOC sensor to obtain in situ calibrated time-series (up to 40 h) of nitrate+nitrite (ΣNOx) and nitrite on the seafloor of the Mauritanian oxygen minimum zone, offshore Western Africa. Initial tests showed that the sensor successfully reproduced water column (160 m) nutrient profiles. Lander deployments at 50, 100 and 170 m depth indicated that the biogeochemical variability was high over the Mauritanian shelf: The 50 m site had the lowest ΣNOx concentration, with 15.2 to 23.4 μM (median=18.3 μM); while at the 100 site ΣNOx varied between 21.0 and 30.1 μM over 40 hours (median = 25.1μM). The 170 m site had the highest median ΣNOx level (25.8 μM) with less variability (22.8 to 27.7 μM). At the 50 m site, nitrite concentration decreased fivefold from 1 to 0.2 μM in just 30 hours accompanied by decreasing oxygen and increasing nitrate concentrations. Taken together with the time series of oxygen, temperature, pressure and current velocities, we propose that the episodic intrusion of deeper waters via cross-shelf transport leads to intrusion of nitrate-rich, but oxygen-poor waters to shallower locations, with consequences for benthic nitrogen cycling. This first validation of an LOC sensor at elevated water depths revealed that when deployed for longer periods and as a part of a sensor network, LOC technology has the potential to contribute to the understanding of the benthic biogeochemical dynamics
The plasticity of near space: evidence for contraction
The distinction between near space and the space farther away has been well established, as has the relation of this distinction to arm length. Recent studies provide evidence for the plasticity of near space, showing that it is possible to expand its extent ("size") through tool-use. In the present study, we examine the converse effect, whether contraction of near space results from increasing the effort involved on a line bisection task. Adult participants bisected lines at different distances, while, in some cases, wearing weights. In Experiment 1, the arms, specifically, were weighted (wrist weights), and in Experiment 2, more general body weights were used (heavy backpack). As in previous studies, unencumbered participants showed leftward bias when bisecting lines at the closest distances and a rightward shift in bias with increasingly farther distances. With wrist weights, but not a heavy backpack, participants showed more rightward bias at the closest distances, and a more gradual rightward shift with increasing distance, as if the nearest locations were represented as being farther away. These results suggest that increased effort, when specifically related to the arm, can serve to reduce the size of near space, providing support for the generally symmetrical plasticity of near space representations
Outcomes of Arthroscopic vs. Open Biceps Tenodesis for Treatment of SLAP Lesion in Female Patients
Background: Biceps tenodesis (BT) is one alternative treatment to repair of superior labrum anterior to posterior (SLAP) tears. It can be performed as an arthroscopy or open procedure. While there have been studies comparing the outcomes of SLAP repair procedures with BT for the treatment of SLAP tears, literature comparing arthroscopic and open BT for the treatment of SLAP tears is limited. Additionally, no previous study has specifically examined the outcomes of these procedures in female patients.
Hypothesis/Purpose: The purpose of this study was to compare outcomes following Arthroscopic BT and Open BT for SLAP tears in females. The authors hypothesized there would be no difference in outcomes between patients who underwent arthroscopic or open procedures.
Study Design: Retrospective Cohort (level III)
Methods: Female patients who underwent arthroscopic or open BT for treatment of SLAP tears between 1/1/2014 and 9/1/2019 were retrospectively reviewed. Patients undergoing a concomitant procedure were excluded. A minimum of 2 years postoperatively patients completed American Shoulder and Elbow Surgeons (ASES), single assessment numerical evaluation (SANE), and visual analog scale (VAS), and a custom return to activity surveys.
Results: This study included 27 female patients; 14 (51.9%) underwent arthroscopic BT and 13 (48.1%) underwent open BT. There was no significant difference between cohorts in terms of age (P = .679), BMI (P = .382), Height (P = .989), Weight (P = .452), laterality of procedure (P = .678), or rate of surgery taking place on the dominant side (P = 1.000). Groups had similar post-operative ASES scores (85.9 vs 73.6, P = .238), SANE scores (81.4 vs 78.6, P = .922), VAS (16.8 vs 32.5, P = .248). Furthermore, rates of participation in sport prior to surgery (P = .236), rate of return to sport following surgery (P = 1.000), and time it took to return to sport (P = .915) were similar between groups.
Conclusion: Female patients undergoing surgical treatment of SLAP lesions with either arthroscopic or open BT show comparable subjective outcomes and return to sport at minimum 2 years. Further research is necessary to define precise treatment indications for this pathology in this specific female patient population
2016-17 Concerto Competition Final Round
The 2016-17 Concerto Competition culminates in this performance featuring students competing to perform as a featured soloist with the KSU Symphony Orchestra on April 26, 2017.https://digitalcommons.kennesaw.edu/musicprograms/1695/thumbnail.jp
Becoming a Viking: DNA testing, genetic ancestry and placeholder identity
A consensus has developed among social and biological scientists around the problematic nature of genetic ancestry testing, specifically that its popularity will lead to greater genetic essentialism in social identities. Many of these arguments assume a relatively uncritical engagement with DNA, under ‘highstakes’ conditions. We suggest that in a biosocial society, more pervasive ‘lowstakes’ engagement is more likely. Through qualitative interviews with participants in a study of the genetic legacy of the Vikings in Northern England, we investigate how genetic ancestry results are discursively worked through. The identities formed in ‘becoming a Viking’ through DNA are characterized by fluidity and reflexivity, rather than essentialism. DNA results are woven into a wider narrative of selfhood relating to the past, the value of which lies in its potential to be passed on within families. While not unproblematic, the relatively banal nature of such narratives within contemporary society is characteristic of the ‘biosociable’
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