Kultúraközvetítés világjárvány idején

A Covid-19 világjárvány rohamos terjedése felülírja eddigi szokásainkat, mindennapi rutinunkat, életvitelünket. Ezért a fenntarthatóságnak kell lennie a következő években az életstratégiánkat alakító alapelvnek. Át kell gondolni eddigi működésünket: mit kell tennünk, tennie a kulturális ágazatnak, hogy megmaradjon a jövőben is, keresetet tudjon biztosítani munkavállalóinak és művészeinek, művelődést, minőségi szabadidőtöltést közönségének. Ennek vizsgálatára 2020 őszén online közönségkutatást végeztem négy közművelődési intézmény bevonásával (Bálint Ágnes Kulturális Központ, Kondor Béla Közösségi Ház, Pestszentimrei Közösségi Ház, Rózsa Művelődési Ház), ez első lépése csak e folyamat megvalósításának, a kutatási eredmények ismeretében a járványügyi intézkedések figyelembevételével olyan eseményeket szervezhetünk – akár online is – melyekkel a megváltozott körülmények között is kiszolgálhatjuk közönségünk igényeit. Az adatfelvétel online felületen, november hónapban történt összesen 864 fő részvételével. A kutatás kiemelt szegmense a Covid-19 kapcsán megváltozott kulturális fogyasztói szokások vizsgálata volt. The rapid spread of the Covid-19 pandemic overwrites our habits, our daily routine and our way of life. For this reason, sustainability must be the guiding principle of our life strategy in the coming years. We need to rethink what we have done so far: what we need to do, what the cultural sector needs to do to stay sustainable in the future, to be able to earn a living for its employees and artists, to provide education and quality leisure time for its audience. To examine this situation, in the autumn of 2020, I conducted an online audience survey involving four public cultural institutions (Ágnes Bálint Cultural Center, Béla Kondor Community House, Pestszentimre Community House, Rózsa Cultural House), which is only the first step in the realization of the process, however, in the knowledge of the research results and with the epidemiological measures, we can organize events – even online – with which we can serve the needs of our audience even in the changed circumstances. I conducted the date collection online in November with the participation of a total of 864 people. The key segment of the research was the study of changed cultural consumer habits in relation to Covid-19

Az alsó szemhéj pótlása tumoreltávolítás után = Replacement of the lower eyelid after tumor removal

Introduction: The full-thickness lower eyelid reconstruction after tumor removal can be a complex challenge. The aim of reconstruction is to reach an appropriate functional and cosmetic result. Objective: To present the retrospective analysis of the reconstruction's experience with the use of Fricke's flap in the case of full-thickness lower eyelid defect. Method: Between January 2010 and December 2020, in the case of 7 patient's after tumor excision on lower eyelid, reconstruction was performed with a modified Fricke's flap. The Fricke's flap was fashioned in the temple region. The patients' average age was 72.8 years. The histological result was basocellular carcinoma in every case. The average follow-up period was 1.9 years. Results: In all cases, good functional and cosmetic result was detected. There were not any flap necrosis and wound dehiscence. In the early postoperative period, temporary edema of the eyelid and conjunctiva was detected. Epiphora occurred in the case of 3 patients and we observed eye irritation caused by skin hair in the case of 1 patient. Tumor recurrence was not detected during the follow-up period. Conclusion: In our experience, the modified Fricke's flap has excellent functional and aesthetic results in the reconstruction after tumor removal on the lower eyelid

Gas Antisolvent Fractionation: a New Method to Obtain Enantiopure Compounds, a Case Study on Mandelic Acid

Micronization processes involving supercritical carbon dioxide are rapid methods to produce fine particles. They also might offer the possibility of using less organic solvent than conventional crystallization methods leading to an environmentally friendlier processing. The separation capabilities of such processes are now demonstrated on the diastereomeric resolution of mandelic acid using (R)-1-phenylethanamine as a resolving agent, utilizing the batch type gas antisolvent fractionation as the separation method. A detailed study was conducted on the effects of the operational parameters pressure (12-20 MPa), temperature (35-55 °C) and co-solvent concentration (33-99 mg/ml). At 12 MPa, 35 °C and 99 mg/ml methanol concentration, a selectivity of 0.52 and a diastereomeric excess of 62% was reached. The same operational parameters were applied during the investigation of the recrystallization-based further purification of the diastereomeric salts, applying the resolving agent in molar equivalent quantity to a non-racemic mixture of mandelic acid. It has been found that the more stable (R)-1-phenylethylammonium-(R)-mandelate salt can be purified to de>98% through four additional recrystallization steps following the initial, half-molar equivalent resolution step

Cornealis elváltozások Wilson-kórban

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New synthetic strategies for xanthene-dye-appended cyclodextrins

Xanthene dyes can be appended to cyclodextrins via an ester or amide bridge in order to switch the fluorescence on or off. This is made possible through the formation of nonfluorescent lactones or lactams as the fluorophore can reversibly cyclize. In this context we report a green approach for the synthesis of switchable xanthene-dye-appended cyclodextrins based on the coupling agent 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM). By using 6-monoamino-β-cyclodextrin and commercially available inexpensive dyes, we prepared rhodamine- and fluorescein-appended cyclodextrins. The compounds were characterized by NMR and IR spectroscopy and MS spectrometry, their UV–vis spectra were recorded at various pH, and their purity was determined by capillary electrophoresis. Two potential models for the supramolecular assembly of the xanthene-dye-appended cyclodextrins were developed based on the set of data collected by the extensive NMR characterization

Két új fejlesztésű pachyméter összehasonlító vizsgálata

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