Social networks and psychological safety: A model of contagion

<p><strong>Purpose:</strong> We attempted to explain how the interactions between members influence the psychological safety of a team using social network analysis by proposing a model based on social contagion in which the psychological safety of the central node has a key role in the psychological safety of the whole team.</p> <p><strong>Design/methodology/approach:</strong> We present a theoretical paper which crosses theory about social network analysis, psychological safety and social contagion.</p> <p><strong>Findings and Originality/value:</strong> We suggest that there are two groups of variables that mediate this relationship. The first group concerns the characteristics of the node and is composed by the proximity to the node’s personal characteristics and the value of the central node as a source of information. Second, we advance that there are two dimensions at the level of tie properties that mediate the influence of a central node on team psychological safety – tie strength and friendship level. Finally, the interacting opportunities- a variable at context level - is considered to affect the strength of the ties.  We also advance some variables that mediate the influence of the psychological safety of a central node on the psychological safety of the team.</p> <p><strong>Originality/value:</strong> To the best of our knowledge there is no significant research using social network analysis to explain the process by which a team becomes psychologically safe. On the other hand, because psychological safety tends to be a team construct it is important to understand how team dynamics, evidenced by social network analysis, influence the formation of psychological safety through contagion processes.</p

Mechanisms of Spontaneous Current Generation in an Inhomogeneous d-Wave Superconductor

A boundary between two d-wave superconductors or an s-wave and a d-wave superconductor generally breaks time-reversal symmetry and can generate spontaneous currents due to proximity effect. On the other hand, surfaces and interfaces in d-wave superconductors can produce localized current-carrying states by supporting the T-breaking combination of dominant and subdominant order parameters. We investigate spontaneous currents in the presence of both mechanisms and show that at low temperature, counter-intuitively, the subdominant coupling decreases the amplitude of the spontaneous current due to proximity effect. Superscreening of spontaneous currents is demonstrated to be present in any d-d (but not s-d) junction and surface with d+id' order parameter symmetry. We show that this supercreening is the result of contributions from the local magnetic moment of the condensate to the spontaneous current.Comment: 4 pages, 5 figures, RevTe

Clinicopathological and toxicological aspects of poisoning by the clomazone herbicide in sheep

AbstractClomazone (2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone) is a herbicide which has been widely used in southern Brazil in the rice cultivation and can be toxic for humans and animals. This study reports the first outbreak poisoning due to clomazone in a flock of 103 sheep, 20 of which showed mainly neurological and respiratory signs. Clomazone was detected in soil and vegetation samples and in the liver, kidney and muscles of poisoned animals. The poisoning was experimentally reproduced in three sheep by the administration of a 134mgkg body weight dose of clomazone. In both the natural and experimental cases, the clinical signs included tachypnea, anorexia, somnolence, weakness and ataxia. Macroscopically, there were no significant changes. Histologically, vacuolization in the white matter, perineuronal vacuoles and congestion of the leptomeningeal and brain vessels were observed. Ultrastructurally, the vacuolar lesions in the brain corresponded to swelling of the dendrites and astrocytic processes. It is concluded that clomazone causes toxic neuropathy in sheep

Real-time image detection for edge devices: a peach fruit detection application

Within the scope of precision agriculture, many applications have been developed to support decision making and yield enhancement. Fruit detection has attracted considerable attention from researchers, and it can be used offline. In contrast, some applications, such as robot vision in orchards, require computer vision models to run on edge devices while performing inferences at high speed. In this area, most modern applications use an integrated graphics processing unit (GPU). In this work, we propose the use of a tensor processing unit (TPU) accelerator with a Raspberry Pi target device and the state-of-the-art, lightweight, and hardware-aware MobileDet detector model. Our contribution is the extension of the possibilities of using accelerators (the TPU) for edge devices in precision agriculture. The proposed method was evaluated using a novel dataset of peaches with three cultivars, which will be made available for further studies. The model achieved an average precision (AP) of 88.2% and a performance of 19.84 frames per second (FPS) at an image size of 640 × 480. The results obtained show that the TPU accelerator can be an excellent alternative for processing on the edge in precision agriculture.info:eu-repo/semantics/publishedVersio

Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea

As hypoxia-induced inflammatory angiogenesis may contribute to sickle cell disease manifestations, we compared the angiogenic molecular profiles of plasma from sickle cell disease individuals and correlated these with in vitro endothelial cell-mediated angiogenesis-stimulating activity and in vivo neovascularization. Bioplex demonstrated that plasma from steady-state sickle cell anemia patients presented elevated concentrations of pro-angiogenic factors (Angiopoietin-1, basic fibroblast growth factor, vascular endothelial growth factor, vascular endothelial growth factor-D and placental growth factor) and displayed potent pro-angiogenic activity, significantly augmenting endothelial cell proliferation, migration and capillary-like structure formation. In vivo neovascularization of Matrigel plugs was significantly greater in sickle cell disease mice, compared with non-sickle cell disease mice, consistent with an upregulation of angiogenesis in the disease. In plasma from patients with hemoglobin SC disease without proliferative retinopathy, anti-angiogenic endostatin and thrombospondin-2 were significantly elevated. In contrast, plasma from hemoglobin SC individuals with proliferative retinopathy displayed a pro-angiogenic profile and had more significant effects on endothelial cell proliferation and capillary formation than plasma of patients without retinopathy. Hydroxyurea therapy was associated with significant reductions in plasma angiogenic factor profile, in association with an inhibition of endothelial cell-mediated angiogenic mechanisms and neovascularization. Thus, sickle cell anemia and retinopathic hemoglobin SC individuals present a highly angiogenic circulating milieu, capable of stimulating key endothelial cell-mediated angiogenic mechanisms. Combination anti-angiogenic therapy for preventing progression of unregulated neovascularization and associated manifestations in sickle cell disease, such as pulmonary hypertension, may be indicated; furthermore, the benefits and drawbacks of the potent anti-angiogenic effects of hydroxyurea should be clarified.As hypoxia-induced inflammatory angiogenesis may contribute to sickle cell disease manifestations, we compared the angiogenic molecular profiles of plasma from sickle cell disease individuals and correlated these with in vitro endothelial cell-mediated an1006730739FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO2008/57441-0; 2009/16334-0565036/201

Revision of the life history parameters (proportion of mature and mean weights at age) for the Iberian (south) sardine stock (ICES 8c and 9a)

Maturity and stock weights at age used in sardine assessment up to 2012 were obatined from (Portuguese and Spanish) spring acoustic surveys biological data. Following a recommendation of the WGANSA, the possible alternative use of the Daily Egg Production Method (DEPM) surveys to estimate maturity at age was evaluated, and a revision of these maturity ogives was undertaken for the last benchmark assessment (Silva et al. 2011, WKPELA 2012), the WG having decided that DEPM maturity ogives should be used in the assessment, and for years with no DEPM survey, 80% of fish mature would be assumed at age 1 (corresponding approximately to the historical mean of DEPM ogives), and for simplicity, 100% of fish are mature at age 2. But these estimates were obtained including information from both DEPM and acoustic surveys: maturity data from the DEPM for each stratum and year were combined to obtain stock estimates, using abundances at age from acoustic surveys as weighting factors; however, in most years, 1-2 months lagged between the two surveys in W and S strata. Revision of weights at age could not be carried out in 2012 due to time constraints, but the WGHANSA believes that it makes more sense that both life history parameters be derived from the same surveys. This WD describes the revision of both maturity and stock weights at age estimates, based uniquely on the DEPM surveys

Dynamics of Robertson-Walker spacetimes with diffusion

We study the dynamics of spatially homogeneous and isotropic spacetimes containing a fluid undergoing microscopic velocity diffusion in a cosmological scalar field. After deriving a few exact solutions of the equations, we continue by analyzing the qualitative behavior of general solutions. To this purpose we recast the equations in the form of a two dimensional dynamical system and perform a global analysis of the flow. Among the admissible behaviors, we find solutions that are asymptotically de-Sitter both in the past and future time directions and which undergo accelerated expansion at all times.Fundação para a Ciência e a Tecnologia (FCT

M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity

A greater understanding of hematopoietic stem cell (HSC) regulation is required for dissecting protective versus detrimental immunity to pathogens that cause chronic infections such as Mycobacterium tuberculosis (Mtb). We have shown that systemic administration of Bacille Calmette-Guérin (BCG) or ß-glucan reprograms HSCs in the bone marrow (BM) via a type II interferon (IFN-II) or interleukin-1 (IL1) response, respectively, which confers protective trained immunity against Mtb. Here, we demonstrate that, unlike BCG or ß-glucan, Mtb reprograms HSCs via an IFN-I response that suppresses myelopoiesis and impairs development of protective trained immunity to Mtb. Mechanistically, IFN-I signaling dysregulates iron metabolism, depolarizes mitochondrial membrane potential, and induces cell death specifically in myeloid progenitors. Additionally, activation of the IFN-I/iron axis in HSCs impairs trained immunity to Mtb infection. These results identify an unanticipated immune evasion strategy of Mtb in the BM that controls the magnitude and intrinsic anti-microbial capacity of innate immunity to infection