Effects of Pre- Exercise Massage on Muscle Soreness

Muscle soreness is common after intense exercise and alternative therapies are always being investigated. Some have indicated possible benefits of massage therapy but this needs to be explored further. Purpose: To determine if a pre-workout massage will help reduce muscle soreness. Methods: Twenty participants (age=30.3±6.3 yrs, ht.=167.6±11.4 cm, wt.=82.5±15.5 kg) were provided five minutes of massage on the right anterior leg and five minutes of massage on the right posterior leg. After completion of the massage, participants performed two sets of squats to a chair, first with an 8lb weight (males) or a 5 lb weight (females) to a metronome that was set to 60 beats per minute. All participants were then instructed to fill out a pain scale over a 24-hour and 48-hour period. Repeated measures ANOVA was used to determine differences in soreness with alpha set at .05. Results: There was no interaction between legs among time points, F(3, 17) = 2.52, p = .092. There was however, a main effect the massaged leg when time was combined, with a lower soreness rating in the massaged leg (5.0±2.4 units) compared to the non-massaged leg (5.8±2.1 units), p = .024. Conclusion: There is potential of reduced soreness after strenuous exercise if massage is obtained prior to activity. Future research should also look at the interactive effect of performance when receiving massage before exercise with intent on reducing soreness

Seasonal patterns of greenhouse gas emissions from a forest-to-bog restored site in northern Scotland : Influence of microtopography and vegetation on carbon dioxide and methane dynamics

Acknowledgments: We thank the Royal Society Protection for Birds (RSPB) for permission to use Lonielist site in Forsinard and the relative stuff for assistance in the field, especially Daniela Klein. We also thank the James Hutton Institute Aberdeen for providing lab and transport facilities. We thank Rebekka Artz and Mhari Coyle (James Hutton Institute) for the provision of their unpublished data and Russell Anderson (Forest Research) and two anonymous referees for improvements to the manuscript. Funding: This research was funded by Scottish Forestry and the University of Aberdeen.Peer reviewedPublisher PD

Hormone-sensitive cyclic GMP-inhibited cyclic AMP phosphodiesterase in rat adipocytes. Regulation of insulin- and cAMP-dependent activation by phosphorylation.

In 32PO4-labeled adipocytes, isoproterenol (ISO) or physiologically relevant concentrations of insulin rapidly increased phosphorylation of a particulate 135-kDa protein which has been identified as a cGMP-inhibited "low Km" cAMP phosphodiesterase (CGI-PDE) by several criteria, including selective immunoprecipitation with anti-CGI-PDE IgG (Degerman, E., Smith, C.J., Tornqvist, H., Vasta, V., Belfrage, P., and Manganiello, V.C. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 533-537). The time courses and concentration dependences for phosphorylation of CGI-PDE by ISO and insulin correlated with CGI-PDE activation in the presence of these agents; effects of ISO were somewhat more rapid than those of insulin. Adenosine deaminase, which metabolizes the adenylate cyclase inhibitor adenosine, also rapidly induced phosphorylation and activation of CGI-PDE. Phenylisopropyladenosine (an adenosine deaminase-resistant adenosine analog) prevented or reversed both adenosine deaminase-stimulated phosphorylation and activation of CGI-PDE (IC50 approximately 0.2 nM). Incubation of adipocytes with 0.1 nM insulin in the presence of ISO rapidly produced 30-200% greater activation and phosphorylation of CGI-PDE than the expected added effects of insulin and ISO individually; both effects preceded the insulin-induced decreases in protein kinase A activity and inhibition of lipolysis. These and other results indicate that CGI-PDE can be phosphorylated at distinct sites and activated by cAMP-dependent and insulin-dependent serine kinase(s), that the activation state of CGI-PDE reflects its relative phosphorylation state, and that synergistic phosphorylation/activation of CGI-PDE may be important in the antilipolytic action of insulin

Assessing soil carbon dioxide and methane fluxes from a Scots pine raised bog-edge-woodland

Acknowledgements: We thank the James Hutton Institute Aberdeen for providing laboratory and transport facilities, especially Richard Hewison, who completed the vegetation survey of the site and Graham Gaskin and Alison Wilkinson for providing assistance with field equipment. Author J Yeluripati was supported by the Scottish Government’s Strategic Research Programme (2016–2021): Research Deliverable 1.1.3: Soils and Greenhouse Gas Emissions. I also thank William Jessop (York University), who provided peat depth measurements and my dearest friends Anna Ferretto, Luka Paradiz Udovc, Douglas Wardell-Johnson, Ben Butler, Lucho Quinzo and Ben M. Taylor for offering their invaluable help with field measurements. We lastly thank Toni Clarcke for helping with statistical analysis and Michael Bell (Forest Research) for improvements to the manuscript. Funding: This research was funded by Scottish Forestry and the University of Aberdeen.Peer reviewedPostprin

Saliva from obese individuals suppresses the release of aroma compounds from wine.

BackgroundRecent evidence suggests that a lower extent of the retronasal aroma release correspond to a higher amount of ad libitum food intake. This has been regarded as one of the bases of behavioral choices towards food consumption in obese people. In this pilot study we investigated the hypothesis that saliva from obese individuals could be responsible for an alteration of the retro-nasal aroma release. We tested this hypothesis in vitro, by comparing the release of volatiles from a liquid food matrix (wine) after its interaction with saliva from 28 obese (O) and 28 normal-weight (N) individuals.Methods and findingsAmplicon sequencing of the 16S rRNA V4 region indicated that Firmicutes and Actinobacteria were more abundant in O, while Proteobacteria and Fusobacteria dominated in N. Streptococcaceae were significantly more abundant in the O subjects and constituted 34% and 19% on average of the saliva microbiota of O and N subjects, respectively. The Total Antioxidant Capacity was higher in O vs N saliva samples. A model mouth system was used to test whether the in-mouth wine aroma release differs after the interaction with O or N saliva. In O samples, a 18% to 60% significant decrease in the mean concentration of wine volatiles was detected as a result of interaction with saliva, compared with N. This suppression was linked to biochemical differences in O and N saliva composition, which include protein content.ConclusionMicrobiological and biochemical differences were found in O vs N saliva samples. An impaired retronasal aroma release from white wine was detected in vitro and linked to compositional differences between saliva from obese and normal-weight subjects. Additional in vivo investigations on diverse food matrices could contribute to understanding whether a lower olfactory stimulation due to saliva composition can be a co-factor in the development/maintenance of obesity

Exploring the Association between Welfare State and Mental Wellbeing in Europe: Does Age Matter?

Previous research reports show mixed results regarding the age gradient in population mental wellbeing, which may be linked to the role that welfare states play. In this study, we investigate whether an age gradient exists in relation to the association between welfare state and mental wellbeing within the adult population in Europe. We combine individual level data from Round 6 of the European Social Survey and country level data on welfare state and use multilevel regression analyses to explore population mental wellbeing. Subjective and psychological wellbeing dimensions were analyzed, and different approaches to measuring welfare state were explored, including a regime typology and composite welfare state measures constructed on the basis of a set of eight individual indicators. We found the age gradient for mental wellbeing to differ between welfare states, with the positive impact of the welfare state increasing with age. A universal and generous welfare state seems to be particularly important for older adults, who are also more likely to be in higher need of transfers and services provided by the welfare state.publishedVersio

Mental well-being among the oldest old: revisiting the model of healthy ageing in a Finnish context

Purpose: This study aimed to examine how participants aged 80 years old or over describe their mental well-being-exploring the suitability of the model of healthy ageing when outlining the mental well-being concept.Methods: Six structured focus group interviews with 28 participants were conducted in Western Finland in 2017. Qualitative content analysis was performed, where both manifest and latent content was considered in a process involving meaning condensation and coding, followed by categorization.Results: The healthy ageing model constituted a useful framework for the conceptualization of mental well-being, illustrating the links between these two constructs. The analysis resulted in a four-dimensional model of mental well-being in oldest old age, the key components being: Activities-enjoyment and fulfilment; Capability-functioning and independence; Orientation-awareness, shifted perspectives and values; and Connectedness-sense of belonging.Conclusions: Although functional status plays an important role for well-being in general, it is not the principal component of self-reported mental well-being within the heterogeneous group of the oldest old. Further, many persons in this age group do not view themselves as passive or dependent, on the contrary, they underline the importance of empowering attitudes, a positive mindset and actively creating circumstances which support their mental well-being

Preparation of hexagonal GeO2 particles with particle size and crystallinity controlled by peptides, silk and silk-peptide chimeras

We demonstrate the use of silk based proteins to control the particle/crystallite size during GeO2 formation, using a bio-mimetic approach at circumneutral pH and ambient temperature. Multicrystalline GeO2 was prepared from germanium tetraethoxide (TEOG) in the presence of different silk-based proteins: Bombyx mori silk (native silk) and two chimeric proteins prepared by linking a germania binding peptide (Ge28: HATGTHGLSLSH) with Bombyx mori silk via chemical coupling at different peptide loadings (silk-Ge28 10% and silk-Ge28 50%). The mineralisation activity of the silk-based proteins was compared with that of peptide Ge28 as a control system. GeO2 mineralisation was investigated in water and in citric acid/bis-tris propane buffer at pH 6. Morphology, particle size, crystallinity, water and organic content of the materials obtained were analysed to study the effect of added biomolecules and mineralisation environment on material properties. In the presence of silk additives well-defined cube-shape hybrid materials composed of hexagonal germania and up to ca. 5 wt% organic content were obtained. The cubic particles ranged from 0.4 to 1.4m in size and were composed of crystalline domains in the range 35-106 nm depending on the additive used and synthesis conditions