3-(2-Hy­droxy­phen­yl)-1-{(E)-[1-(pyrazin-2-yl)ethyl­idene]amino}­thio­urea monohydrate

In the title compound, C13H13N5OS·H2O, the thio­urea mol­ecules closely resemble each other and are approximately planar; the dihedral angles formed between the terminal benzene rings are 7.88 (8) and 7.20 (8)°, respectively. The observed planarity correlates with the presence of bifurcated N—H⋯(O,N) hydrogen bonds. In the crystal, the mol­ecules are connected into supra­molecular double chains via a combination of N—H⋯S (linking the two independent mol­ecules), O—H⋯O and O—H⋯N (linking dimeric aggregates into a supra­molecular chain via hy­droxy–water, water–water and water–pyrazine inter­actions) and O—H⋯S hydrogen bonds (connecting two chains). The chains are further connected by C—H⋯N and C—H⋯S inter­actions

Students’ knowledge in the waqf land concept / Siti Nadiah Mohd Ali ... [et al.]

Waqf is an endowment made by a Muslim for religious, educational, or other charitable causes. To promote thewaqf concept amongst Muslims, we investigated students’ knowledge at the university level. In the earlier stages, it should start from the educational system which is near to the students. Muslims may not realise this waqf concept if they are not aware of or don’t want to know about it. Since Real Estate Management programmes have a significant relationship with waqf, the purpose of this paper is to investigate the level of knowledge in the waqf land concept by Muslim students who have studied Real Estate Management. It has been focused on endowment made by the Muslims and potential career opportunities for Real Estate Management students in waqf management in Malaysia. This study has been limited amongst undergraduates of Universiti Teknologi MARA Perak who studied Real Estate Management in the District of Perak Tengah. The quantitative method has been used in the data collection and analysis of this study. Structured questionnaires were distributed amongst students in the universitiy. Data from the questionnaires were analysed using the IBM SPSS software. The result findings indicated that the level of knowledge on the waqf concept amongst Real Estate Management university students is good. The result of this study did not show any significant difference in the knowledge in the waqf land concept between male and female students and there was no significant difference in the level of knowledge amongst students from different levels of CGPA. Therefore, this paper will propose to the Department of Estate Management to take into consideration to include waqf development as one of the major syllabus subjects in their programme in order to make sure the knowledge and practical development amongst Muslim students after graduations can benefit waqf performances in Malaysia, efficiently

(E,E)-1,2-Bis[3-meth­oxy-4-(prop-2-yn-1-yl­oxy)benzyl­idene]hydrazine

The complete mol­ecule in the title compound, C22H20N2O4, is generated by the application of an inversion centre. With the exception of the terminal acetyl­ene groups [C—O—C—C = −78.02 (17)°], the remaining atoms constituting the mol­ecule are essentially coplanar. The configuration around the C=N bond [1.282 (2) Å] is E. The formation of supra­molecular chains mediated by C—H⋯O inter­actions, occurring between methyl­ene H and meth­oxy O atoms, is the most notable feature of the crystal packing

4-(4-Hy­droxy­methyl-1H-1,2,3-triazol-1-yl)benzoic acid

In the title compound, C10H9N3O3, there is a small twist between the benzene and triazole rings [dihedral angle = 6.32 (7)°]; the carb­oxy­lic acid residue is almost coplanar with the benzene ring to which it is attached [O—C—C—C torsion angle = 1.49 (19)°]. The main deviation from coplanarity of the non-H atoms is found for the hy­droxy group which is almost perpendicular to the remaining atoms [N—C—C—O torsion angle = −75.46 (16)°]. In the crystal, the presence of O—H⋯O (between carboxyl groups) and O—H⋯N (between the hy­droxy group and the triazole ring) hydrogen bonds leads to supra­molecular chains along [03]. The chains are connected into sheets via C—H⋯O(hy­droxy) inter­actions

2-Methyl-3-[(4-methyl­phen­yl)sulfon­yl­oxy]-2-{[(4-methyl­phen­yl)sulfon­yloxy]meth­yl}propyl 4-methyl­benzene­sulfonate

The title mol­ecule, C26H30O9S3, adopts an extended conformation whereby two approximately parallel benzene rings [dihedral angle = 8.32 (10)°] are orientated in opposite directions along the pseudo-threefold axis through the central quaternary C atom, while a third ring occupies a position mid-way and face-on to these rings [dihedral angles = 82.28 (10) and 78.81 (7)°]. The crystal packing is dominated by C—H⋯O contacts and π–π inter­actions [ring centroid distance = 3.6902 (12) Å]

Synthesis, characterization, and evaluation of silver(I) complexes with mixed-ligands of thiosemicarbazones and diphenyl(p-tolyl)phosphine as biological agents

Five new silver(I) complexes were synthesized with mixed ligands of thiosemicarbazone derivatives and diphenyl(p-tolyl)phosphine in search of new biologically active compounds. A CHN elemental analysis, powder X-ray diffraction (PXRD) data and several spectroscopic techniques such as Fourier-transform infrared spectroscopy, energy-dispersive X-ray, 1 H, 13 C, and 31 P{ 1 H} NMR were performed to elucidate the structure of these complexes. Elemental analysis suggested that the stoichiometry of the complexes formed by the reaction of silver nitrate with thiosemicarbazone in the presence of (p-tolyl)PPh 2 was indeed 1:2:1 molar ratio. The silver ions were discovered to be coordinated to the sulfur of thiosemicarbazone and phosphorus of (p-tolyl)PPh 2 , having a tetrahedral geometry based on the spectroscopic data obtained. The PXRD patterns were studied to see the degree of crystallinity of the complexes. The in vitro antiproliferative activity of these complexes was investigated toward the MDA-MB-231 and MCF-7 breast cancer cell lines, as well as the HT-29 colon cancer cell line, which yielded IC 50 values in low micromolar range. The antiplasmodial activity of these complexes was also examined against chloroquine-resistant Plasmodium falciparum parasite which demonstrated good activity and further tested for their selectivity index. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group