82 research outputs found
ΠΡΡΠΎΡΠΈΠ°ΡΠΈΠ²Π½ΡΠ΅ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎΠ·Ρ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Π»ΠΎΡΠ°Π΄Π΅ΠΉ ΠΈ ΠΎΡΠ΅Π½ΠΊΠ° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΏΡΠΎΡΠΈΠ²ΠΎΠΏΠ°ΡΠ°Π·ΠΈΡΠ°ΡΠ½ΡΡ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ²
Invasive diseases of horses are an urgent problem in the horse breeding industry of the Republic of Belarus, as well as in the near and far abroad countries. The main role among the parasitic pathology is occupied by helminths of the small and large intestine, as well as larvae of gasterophilus. In associative course, they are the cause of significant economic losses associated with the growth and development of sick young animals, reduced performance, endurance of animals, increased susceptibility to other diseases, and even the death of animals. Planned therapeutic and preventive measures using broad-spectrum anthelmintics is a priority measure to reduce economic damage in development of the horse breeding industry. The paper provides data on spread of parasitoses of gastrointestinal tract in horses in the Republic of Belarus during period of 2004-2020. The paper presents the species composition of horse parasites localized in the stomach, small and large intestines. Data on extensiveness and intensity of invasions of horses by parasitocenosis of digestive tract in terms of age are presented. Therapeutic efficiency of antiparasitic drugs of various pharmacological groups in mono- and polyinfestations of gastrointestinal tract of horses are studied. High extensibility of Avermectin series preparations (Avermectin paste 1 %, Rivertin 1 %) has been determined for nematodes of gastrointestinal tract of horses and gastrointestinal disease. High efficiency has been obtained from a new complex antiparasitic preparation for horses βPrazimaxβ in mono- and polyinfestations caused by parasites of gastrointestinal tract, including nematodes of the small and large intestines, larvae of gasterophilus and Anoplocephala perfoliata cestodes. Data on spread of associative course of parasitocenoses of the digestive tract of horses, age and seasonal dynamics will allow veterinary specialists to make timely diagnosis, conduct differential diagnostics, determine the optimal timing of diagnostic, therapeutic and preventive treatments, taking into account the specifics of parasitocenosis.ΠΠ½Π²Π°Π·ΠΈΠΎΠ½Π½ΡΠ΅ Π±ΠΎΠ»Π΅Π·Π½ΠΈ Π»ΠΎΡΠ°Π΄Π΅ΠΉ ΡΠ²Π»ΡΡΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΎΠΉ Π² ΠΊΠΎΠ½Π΅Π²ΠΎΠ΄ΡΠ΅ΡΠΊΠΈΠΉ ΠΎΡΡΠ°ΡΠ»ΠΈ Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΈ ΠΠ΅Π»Π°ΡΡΡΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΡΡΠ°Π½ Π±Π»ΠΈΠΆΠ½Π΅Π³ΠΎ ΠΈ Π΄Π°Π»ΡΠ½Π΅Π³ΠΎ Π·Π°ΡΡΠ±Π΅ΠΆΡΡ. ΠΡΠ½ΠΎΠ²Π½ΡΡ ΡΠΎΠ»Ρ ΡΡΠ΅Π΄ΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠ°ΡΠ½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ Π·Π°Π½ΠΈΠΌΠ°ΡΡ Π³Π΅Π»ΡΠΌΠΈΠ½ΡΡ ΡΠΎΠ½ΠΊΠΎΠ³ΠΎ ΠΈ ΡΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»ΠΎΠ² ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ°, Π° ΡΠ°ΠΊΠΆΠ΅ Π»ΠΈΡΠΈΠ½ΠΊΠΈ Π³Π°ΡΡΠ΅ΡΠΎΡΠΈΠ»ΡΡΠΎΠ². ΠΡΠΈ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠ²Π½ΠΎΠΌ ΡΠ΅ΡΠ΅Π½ΠΈΠΈ ΠΎΠ½ΠΈ ΡΠ²Π»ΡΡΡΡΡ ΠΏΡΠΈΡΠΈΠ½ΠΎΠΉ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΠΎΡΠ΅ΡΡ, ΡΠ²ΡΠ·Π°Π½Π½ΡΡ
Ρ ΡΠΎΡΡΠΎΠΌ ΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΠΏΠ΅ΡΠ΅Π±ΠΎΠ»Π΅Π²ΡΠ΅Π³ΠΎ ΠΌΠΎΠ»ΠΎΠ΄Π½ΡΠΊΠ°, ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ΠΌ ΡΠ°Π±ΠΎΡΠΎΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ, Π²ΡΠ½ΠΎΡΠ»ΠΈΠ²ΠΎΡΡΠΈ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
, ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ΠΌ Π²ΠΎΡΠΏΡΠΈΠΈΠΌΡΠΈΠ²ΠΎΡΡΠΈ ΠΊ Π΄ΡΡΠ³ΠΈΠΌ Π±ΠΎΠ»Π΅Π·Π½ΡΠΌ ΠΈ Π΄Π°ΠΆΠ΅ Π³ΠΈΠ±Π΅Π»ΠΈ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΏΠ»Π°Π½ΠΎΠ²ΡΡ
Π»Π΅ΡΠ΅Π±Π½ΠΎ-ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΠΉ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ Π°Π½ΡΠΈΠ³Π΅Π»ΡΠΌΠΈΠ½ΡΠΈΠΊΠΎΠ² ΡΠΈΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΏΠ΅ΠΊΡΡΠ° Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΡΠΈΠΎΡΠΈΡΠ΅ΡΠ½ΠΎΠΉ ΠΌΠ΅ΡΠΎΠΉ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΡΠ΅ΡΠ±Π° Π² ΡΠ°Π·Π²ΠΈΡΠΈΠΈ ΠΎΡΡΠ°ΡΠ»ΠΈ ΠΊΠΎΠ½Π΅Π²ΠΎΠ΄ΡΡΠ²Π°. Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠΈΠ²ΠΎΠ΄ΡΡΡΡ ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΏΠΎ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΡ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎΠ·ΠΎΠ² ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Π»ΠΎΡΠ°Π΄Π΅ΠΉ Π½Π° ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΈ ΠΠ΅Π»Π°ΡΡΡΡ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ 2004β2020 Π³Π³. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ Π²ΠΈΠ΄ΠΎΠ²ΠΎΠΉ ΡΠΎΡΡΠ°Π² ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎΠ² Π»ΠΎΡΠ°Π΄Π΅ΠΉ, Π»ΠΎΠΊΠ°Π»ΠΈΠ·ΡΡΡΠΈΡ
ΡΡ Π² ΠΆΠ΅Π»ΡΠ΄ΠΊΠ΅, ΡΠΎΠ½ΠΊΠΎΠΌ ΠΈ ΡΠΎΠ»ΡΡΠΎΠΌ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ΅. ΠΠ·ΡΡΠ΅Π½Ρ Π΄Π°Π½Π½ΡΠ΅ ΠΏΠΎ ΡΠΊΡΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈΠ½Π²Π°Π·ΠΈΠΉ Π»ΠΎΡΠ°Π΄Π΅ΠΉ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎΡΠ΅Π½ΠΎΠ·Π°ΠΌΠΈ ΠΏΠΈΡΠ΅Π²Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΌ Π°ΡΠΏΠ΅ΠΊΡΠ΅. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Π° ΡΠ΅ΡΠ°ΠΏΠ΅Π²ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠΎΡΠΈΠ²ΠΎΠΏΠ°ΡΠ°Π·ΠΈΡΠ°ΡΠ½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π³ΡΡΠΏΠΏ ΠΏΡΠΈ ΠΌΠΎΠ½ΠΎ- ΠΈ ΠΏΠΎΠ»ΠΈΠΈΠ½Π²Π°Π·ΠΈΡΡ
ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Π»ΠΎΡΠ°Π΄Π΅ΠΉ. ΠΠΎΠΊΠ°Π·Π°Π½Π° Π²ΡΡΠΎΠΊΠ°Ρ ΡΠΊΡΡΠ΅Π½ΡΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² Π°Π²Π΅ΡΠΌΠ΅ΠΊΡΠΈΠ½ΠΎΠ²ΠΎΠ³ΠΎ ΡΡΠ΄Π° (Π°Π²Π΅ΡΠΌΠ΅ΠΊΡΠΈΠ½ΠΎΠ²Π°Ρ ΠΏΠ°ΡΡΠ° 1 %, ΡΠΈΠ²Π΅ΡΡΠΈΠ½ 1 %, ΡΠ½ΠΈΠ²Π΅ΡΠΌ) ΠΏΡΠΈ Π½Π΅ΠΌΠ°ΡΠΎΠ΄ΠΎΠ·Π°Ρ
ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Π»ΠΎΡΠ°Π΄Π΅ΠΉ ΠΈ Π³Π°ΡΡΠ΅ΡΠΎΡΠΈΠ»Π΅Π·Π΅. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Π° Π²ΡΡΠΎΠΊΠ°Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΎΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΈΠ²ΠΎΠΏΠ°ΡΠ°Π·ΠΈΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ° Π΄Π»Ρ Π»ΠΎΡΠ°Π΄Π΅ΠΉ Β«ΠΡΠ°Π·ΠΈΠΌΠ°ΠΊΡΒ» ΠΏΡΠΈ ΠΌΠΎΠ½ΠΎ- ΠΈ ΠΏΠΎΠ»ΠΈΠΈΠ½Π²Π°Π·ΠΈΡΡ
, Π²ΡΠ·Π²Π°Π½Π½ΡΡ
ΠΏΠ°ΡΠ°Π·ΠΈΡΠ°ΠΌΠΈ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ°, ΡΡΠ΅Π΄ΠΈ ΠΊΠΎΡΠΎΡΡΡ
Π½Π΅ΠΌΠ°ΡΠΎΠ΄Ρ ΡΠΎΠ½ΠΊΠΎΠ³ΠΎ ΠΈ ΡΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ°, Π»ΠΈΡΠΈΠ½ΠΊΠΈ Π³Π°ΡΡΠ΅ΡΠΎΡΠΈΠ»ΡΡΠΎΠ² ΠΈ ΡΠ΅ΡΡΠΎΠ΄Ρ Π²ΠΈΠ΄Π° Anoplocephala perfoliata. ΠΠ°Π½Π½ΡΠ΅ ΠΎ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΠΈ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎΡΠ΅Π½ΠΎΠ·ΠΎΠ² ΠΏΠΈΡΠ΅Π²Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Π»ΠΎΡΠ°Π΄Π΅ΠΉ, Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΉ ΠΈ ΡΠ΅Π·ΠΎΠ½Π½ΠΎΠΉ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡ Π²Π΅ΡΠ΅ΡΠΈΠ½Π°ΡΠ½ΡΠΌ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠ°ΠΌ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎ ΠΏΠΎΡΡΠ°Π²ΠΈΡΡ Π΄ΠΈΠ°Π³Π½ΠΎΠ·, ΠΏΡΠΎΠ²Π΅ΡΡΠΈ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΡ, ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΡΡΠΎΠΊΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
, Π»Π΅ΡΠ΅Π±Π½ΡΡ
ΠΈ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΠ±ΡΠ°Π±ΠΎΡΠΎΠΊ Ρ ΡΡΠ΅ΡΠΎΠΌ ΡΠΏΠ΅ΡΠΈΡΠΈΠΊΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎΡΠ΅Π½ΠΎΠ·Π°
Optical polarization observations with the MASTER robotic net
We present results of optical polarization observations performed with the
MASTER robotic net for three types of objects: gamma-ray bursts, supernovae,
and blazars. For the Swift gamma-ray bursts GRB100906A, GRB110422A, GRB121011A,
polarization observations were obtained during very early stages of optical
emission. For GRB100906A it was the first prompt optical polarization
observation in the world. Photometry in polarizers is presented for Type Ia
Supernova 2012bh during 20 days, starting on March 27, 2012. We find that the
linear polarization of SN 2012bh at the early stage of the envelope expansion
was less than 3%. Polarization measurements for the blazars OC 457, 3C 454.3,
QSO B1215+303, 87GB 165943.2+395846 at single nights are presented. We infer
the degree of the linear polarization and polarization angle. The blazars OC
457 and 3C 454.3 were observed during their periods of activity. The results
show that MASTER is able to measure substantially polarized light; at the same
time it is not suitable for determining weak polarization (less than 5%) of dim
objects (fainter than 16). Polarimetric observations of the optical
emission from gamma-ray bursts and supernovae are necessary to investigate the
nature of these transient objects.Comment: 31 pages, 12 figures, 4 tables; Exposure times in Table 2 have been
correcte
Microwave Assisted Synthesis of Py-Im Polyamides
Microwave synthesis was utilized to rapidly build Py-Im polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5β²-WGWWCW-3β² (W = A or T) subset of the consensus Androgen and Glucocorticoid Response Elements was synthesized in 56% yield after 20 linear steps and HPLC purification. It was confirmed by Mosher amide derivatization of the polyamide that a chiral Ξ±-amino acid does not racemize after several additional coupling steps
Prevention of ulcer disease in goldfish by means of vaccination
A vaccine comprising cells of Aeromonas bestiarum grown in tryptic soy broth and atypical A. salmonicida cells produced in iron-limited and iron-supplemented media protected goldfish Carassius auratus when administered by immersion (dosage ≈ 5 × 107 cells/mL for 60 s) followed after 28 d by an oral booster (dosage = 5 × 107 cells/g of feed), which was fed for 7 d so that each fish received about 1 g of vaccine-containing feed. After challenge by intramuscular injection of a virulent culture of atypical A. salmonicida, the relative percent survival (RPS) was more than 90%. The approach was more successful than using a commercial furunculosis vaccine with or without supplementation with A. bestiarum or atypical A. salmonicida cells. Moreover, a smooth derivative of the virulent rough culture of atypical A. salmonicida was less effective as a vaccine candidate, yielding an RPS of only 65%. Low antibody titers of 1:39–1:396 were found in the vaccinated fish. The vaccinated fish had a significantly higher proportion of dead head kidney macrophages (10.9 ± 3.5%; P = 0.0149) than did the controls (6.8 ± 3.1%). However, differences in the number of erythrocytes and leukocytes, the level of phagocytic and lysozyme activities, and the proportion of lymphocytes, monocytes, and polymorphonuclear cells were not statistically significant between the two groups
Otogenic Sinus Thrombosis and Hemophilia: A Clinical Case
Background. Patients with hemophilia are protected from thrombosis by a deficiency of one of coagulation factors, therefore thrombotic complications are rare in them. Currently, few descriptions of spontaneous venous thrombosis in adult hemophiliacs can be found in the literature. Even fewer data of thromboembolic complications are reported in pediatric practice. At present, no clear recommendations are given for the management of thrombotic complications in children with hemophilia, which requires further study of this issue to develop prevention and treatment regimens, including otogenic sinus thrombosis in this category of patients.Case description. A 7-year-old boy was transferred from the Somatic Hospital to the Intensive Care Unit of Regional Clinical Hospital No. 2 in Tyumen (Russia) with an Otorhinolaryngology Unit. He was diagnosed with non-perforative form of acute right-sided suppurative otitis media, acute right-sided mastoiditis, thrombosis of the right sigmoid sinus. The anamnesis shows that the child is diagnosed with hemophilia A, of moderate severity (factor VIII level β 5%), for which he has been receiving factor VIII replacement therapy for the last year. Upon admission, a general blood test revealed no abnormalities, with a slight increase in acute-phase parameters: C-reactive protein, fibrinogen, signs of hypocoagulation. Due to negative dynamics, the child underwent anthromastoidotomy against the background of intensive replacement therapy. Surgery revealed the presence of granulation tissue with hemorrhagic thrombi in the antrum and aditus. In the postoperative period, replacement therapy was accompanied with antibacterial and anticoagulant therapy.Conclusion. The management of patients with otogenic sinus thrombosis against the background of hereditary factor VIII deficiency is a difficult task. On the one hand, it requires surgical intervention and anticoagulant therapy in order to prevent further thrombosis, on the other hand β intensive replacement therapy in order to reduce the risks of hemorrhagic complications. The described case demonstrates the need for an interdisciplinary approach to the diagnosis and treatment of a patient with otogenic thrombosis of lateral sinus against the background of hemophilia A. The approach is to minimize the risks of intraoperative complications and insure a favorable outcome
The optical identifcation of events with poorly defined locations: The case of the Fermi GBM GRB140801A
We report the early discovery of the optical afterglow of gamma-ray burst
(GRB) 140801A in the 137 deg 3- error-box of the Fermi Gamma-ray
Burst Monitor (GBM). MASTER is the only observatory that automatically react to
all Fermi alerts. GRB 140801A is one of the few GRBs whose optical counterpart
was discovered solely from its GBM localization. The optical afterglow of GRB
140801A was found by MASTER Global Robotic Net 53 sec after receiving the
alert, making it the fastest optical detection of a GRB from a GBM error-box.
Spectroscopy obtained with the 10.4-m Gran Telescopio Canarias and the 6-m BTA
of SAO RAS reveals a redshift of . We performed optical and
near-infrared photometry of GRB 140801A using different telescopes with
apertures ranging from 0.4-m to 10.4-m. GRB 140801A is a typical burst in many
ways. The rest-frame bolometric isotropic energy release and peak energy of the
burst is erg and
keV, respectively, which is consistent with the
Amati relation. The absence of a jet break in the optical light curve provides
a lower limit on the half-opening angle of the jet deg. The
observed is consistent with the limit derived from the
Ghirlanda relation. The joint Fermi GBM and Konus-Wind analysis shows that GRB
140801A could belong to the class of intermediate duration. The rapid detection
of the optical counterpart of GRB 140801A is especially important regarding the
upcoming experiments with large coordinate error-box areas.Comment: in press MNRAS, 201
Development of DNA-Biochip for Identification of Influenza A Virus Subtypes
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase subtypes N1,N2 of influenza virus. This microchip was successfully tested on the strains of A/H5N1 highly pathogenic avian influenza virus, A/H1N1(2009) pandemic influenza virus, A/H1N1 and A/H3N2 seasonal influenza viruses
Universal Oligonucleotide Microarray for Sub-Typing of Influenza A Virus
A universal microchip was developed for genotyping Influenza A viruses. It contains two sets of oligonucleotide probes allowing viruses to be classified by the subtypes of hemagglutinin (H1βH13, H15, H16) and neuraminidase (N1βN9). Additional sets of probes are used to detect H1N1 swine influenza viruses. Selection of probes was done in two steps. Initially, amino acid sequences specific to each subtype were identified, and then the most specific and representative oligonucleotide probes were selected. Overall, between 19 and 24 probes were used to identify each subtype of hemagglutinin (HA) and neuraminidase (NA). Genotyping included preparation of fluorescently labeled PCR amplicons of influenza virus cDNA and their hybridization to microarrays of specific oligonucleotide probes. Out of 40 samples tested, 36 unambiguously identified HA and NA subtypes of Influenza A virus
The MASTER-II network of robotic optical telescopes. First results
The main stages in the creation of the Russian segment of the MASTER network of robotic telescopes is described. This network is designed for studies of the prompt optical emission of gammaray bursts (GRBs; optical emission synchronous with the gamma-ray radiation) and surveys of the sky aimed at discovering uncataloged objects and photometric studies for various programs. The first results obtained by the network, during its construction and immediately after its completion in December 2010, are presented. Eighty-nine alert pointings at GRBs (in most cases, being the first ground telescopes to point at the GRBs) were made from September 2006 through July 2011. The MASTER network holds first place in the world in terms of the total number of first pointings, and currently more than half of first pointings at GRBs by ground telescopes are made by the MASTER network. Photometric light curves of GRB 091020, GRB 091127, GRB 100901A, GRB 100906A, GRB 10925A, GRB 110106A, GRB 110422A, and GRB 110530A are presented. It is especially important that prompt emission was observed for GRB 100901A and GRB 100906A, and thar GRB 091127, GRB 110422A, and GRB 110106A were observed from the first seconds in two polarizations. Very-wide-field cameras carried out synchronous observations of the prompt emission of GRB 081102, GRB 081130B, GRB 090305B, GRB 090320B, GRB 090328, and GRB 090424. Discoveries of Type Ia supernovae are ongoing (among them the brightest supernova in 2009): 2008gy, 2009nr, 2010V, and others. In all, photometry of 387 supernovae has been carried out, 43 of which were either discovered or first observed with MASTER telescopes; more than half of these are Type Ia supernovae. Photometric studies of the open clusters NGC 7129 and NGC 7142 have been conducted, leading to the discovery of 38 variable stars. Sixty-nine optical transients have been discovered. Β© 2013 Pleiades Publishing, Ltd
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