Multidisciplinary Versus One-on-One Setting: A Qualitative Study of Clinicians' Perceptions of Their Relationship With Patients With Prostate Cancer

The authors' evaluation of the pros and cons of the multidisciplinary approach indicates that the dynamism inherent in multidisciplinary care represents a challenge, which may explain why clinicians appear to prefer communication in a one-on-one setting

Treatment decision-making process of men with newly diagnosed localized PCa: the role of multidisciplinary approach in patient engagement

The diagnosis of prostate cancer (PCa) often represents a stressful event. In addition to the psychological distress related to the diagnosis, patients face challenging health decisions: in fact, besides radical  treatments, Active Surveillance may represent an option for patients with diagnosis of localized PCa. A multidisciplinary clinical approach seems to represent the suitable organizational model to meet such a requirement, optimising the therapeutic outcome for PCa patients.The present study is a qualitative examination of the treatment decision-making process of men with a newly diagnosed localized PCa who received a multidisciplinary clinical consultation. Results suggest that a multidisciplinary approach may satisfy patients’ need to be comprehensively informed about all their chances and options of curing and managing the disease. Together with information, patients need to build a therapeutic relationship with the physicians in order to share their treatment decision-making experience. If this does not occur, frustration, confusion and other negative emotions may emerge

Efficient Implementation of Application-Aware Spinlock Control in MPSoCs

Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G × E), however, so far, thorough replication of findings is rare and G × E research still faces several conceptual and methodological challenges. In this article, we aim to review these recent developments and illustrate how integrated, large-scale investigations may overcome contemporary challenges in G × E research, drawing on the example of a large, international, multi-center study into the identification and translational application of G × E in schizophrenia. While such investigations are now well underway, new challenges emerge for G × E research from late-breaking evidence that genetic variation and environmental exposures are, to a significant degree, shared across a range of psychiatric disorders, with potential overlap in phenotyp