Pattern recognition on a quantum computer

By means of a simple example it is demonstrated that the task of finding and identifying certain patterns in an otherwise (macroscopically) unstructured picture (data set) can be accomplished efficiently by a quantum computer. Employing the powerful tool of the quantum Fourier transform the proposed quantum algorithm exhibits an exponential speed-up in comparison with its classical counterpart. The digital representation also results in a significantly higher accuracy than the method of optical filtering. PACS: 03.67.Lx, 03.67.-a, 42.30.Sy, 89.70.+c.Comment: 6 pages RevTeX, 1 figure, several correction

Are two heads better than one? System school leadership explained and critiqued

‘System leadership’, as applied to the running of schools, refers to a form of leadership that extends beyond a single institution, where headteachers work with establishments other than their own. This approach is predicated on certain beliefs about the role and purpose of collaborative school leadership and management in a marketised system of state schooling and the benefits of a distributed and networked approach to school improvement. But what are the potential benefits and limitations of school system leadership? What normative interpretations of the system are best suited for purpose? This paper explores these issues with reference to the English school system, where system leadership is actively promoted by government through education policy and school reform. In order to do this, use is made of Gunter, H., D. Hall, and J. Bragg (2013. “Distributed Leadership: A Study in Knowledge Production.” Education Management, Administration and Leadership 41 (4): 555–580.) framework of distributed leadership in schools. The framework identifies functionally normative, functionally descriptive, critical and socially critical positions in the school leadership literature. The paper concludes by putting forward potential alternatives to the largely functional policy narratives and solutions of recent decades, which are based on a broader understanding of ‘the system’

Exercise-induced respiratory muscle work: Effects on blood flow, fatigue and performance

This is the post print version of this article. The official published version can be obtained from the link below.In healthy subjects, heavy intensity endurance exercise places substantial demands on the respiratory muscles as breathing frequency, ventilation and the work of breathing rise over time. In the highly trained subject working at high absolute work rates, the ventilatory demand often causes varying degrees of expiratory flow limitation, sometimes accompanied by lung hyperinflation and, therefore, increased elastic work of breathing. Time-dependant increases in effort perceptions for both dyspnea and limb discomfort accompany these increased ventilatory demands. Similar responses to endurance exercise but at much lower exercise intensities also occur in patients with COPD and CHF. Note that these responses significantly influence exercise performance times in both health and disease. This effect was demonstrated by the marked reductions in the rate of rise of effort perceptions and the enhanced exercise performance times elicited by unloading the respiratory muscles using pressure support ventilation or proportional assist mechanical ventilation. In healthy fit subjects, unloading the inspiratory work of breathing by about one half increased performance by an average of 14% (Harms et al. 2000), and in CHF and COPD patients performance time more than doubled with respiratory muscle unloading (O’Donnell et al. 2001). Why are effort perceptions of limb discomfort markedly reduced and exercise performance increased when the respiratory muscles are unloaded? Our hypothesis is shown in Fig. 1

Emerging patterns of Multi-Academy Trusts and school sponsorship in England

The number of the schools in England moving from local authority control to central government control by becoming academies has grown rapidly since 2010 when the new academies agenda was instigated. More recently, the number of academies forming groups of academies – Multi-Academy Trusts (MATs) – which are distinct legal entities, has also grown rapidly. Together, these two changes, academisation and MATs, represent one of the most significant structural changes to the state education system in England since the Butler Education Act of 1944. The configuration of groups of schools into MATs has produced a diverse landscape of organisational structures and bodies responsible for the management and oversight of state funded schooling. MATs are extremely diverse structures, having a range of lead institutions, organisations and individuals. There is also a wide variance in geographic spread. Set against the socio-political and economic background of globalisation, these changes reflect one way in which the English government has responded to the opening up of public services, including schools, to private business interests and international capital. In becoming academies schools move out of local authority control and ‘buy in’ advice and support services. For example, responsibilities traditionally held by local authorities for intervening in and supporting inadequately performing schools have been taken on by so-called ‘sponsoring academies’. In essence, schools that are performing inadequately are required to become academies and join a MAT. Within the MAT will be a sponsoring academy, which has specific responsibilities for improving the inadequately performing school. The study is based on analysis of the Department for Education’s Edubase2 database relating to Academy sponsorship. It aims to describe emerging patterns of MATs paying particular attention to size, geographical spread, school type and sponsorship arrangements. The role of the Regional Schools’ Commissioners in allocating Sponsors and underperforming schools is also of interest here. Answers to the following questions were considered: ● Why would schools chose to become sponsoring academies? ● How is the arrangement brokered - particularly where sponsorship may cross geographical/county borders? ● What are the sponsorship arrangements? ● Is sponsorship short-term e.g. until the sponsored school meets satisfactory standards of performance or long-term? ● What are the opportunities and risks of academy sponsorship

Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis

Indexación: Scopus.Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring. Previous studies have shown that maternal hypothyroidism increases the severity of experimental autoimmune encephalomyelitis (EAE), an autoimmune disease model for multiple sclerosis (MS). Here, we analyzed the immune response after EAE induction in the adult offspring gestated in Hpx. Mice gestated in Hpx showed an early appearance of EAE symptoms and the increase of all parameters of the disease such as: the pathological score, spinal cord demyelination, and immune cell infiltration in comparison to the adult offspring gestated in euthyroidism. Isolated CD4+CD25+ T cells from spleen of the offspring gestated in Hpx that suffer EAE showed reduced capacity to suppress proliferation of effector T cells (TEff) after being stimulated with anti-CD3 and anti-CD28 antibodies. Moreover, adoptive transfer experiments of CD4+CD25+ T cells from the offspring gestated in Hpx suffering EAE to mice that were induced with EAE showed that the receptor mice suffer more intense EAE pathological score. Even though, no significant differences were detected in the frequency of Treg cells and IL-10 content in the blood, spleen, and brain between mice gestated in Hpx or euthyroidism, T cells CD4+CD25+ from spleen have reduced capacity to differentiate in vitro to Treg and to produce IL-10. Thus, our data support the notion that maternal Hpx can imprint the immune response of the offspring suffering EAE probably due to a reduced capacity to trigger suppression. Such "imprints" on the immune system could contribute to explaining as to why adult offspring gestated in Hpx suffer earlier and more intense EAE. © 2018 Haensgen, Albornoz, Opazo, Bugueño, Jara Fernández, Binzberger, Rivero-Castillo, Venegas Salas, Simon, Cabello-Verrugio, Elorza, Kalergis, Bueno and Riedel.https://www.frontiersin.org/articles/10.3389/fimmu.2018.01257/ful

On the assessment of time-shift variations from backscattered ultrasound for large temperature changes in biological phantoms

This work reports the assessment of time-shifts (TS) from backscattered ultrasound (BSU) signals when large temperature variations (up to 15 degrees C) were induced in a gel-based phantom. The results showed that during cooling temperature is linear with TS at a rate of approximately 74 ns/degrees C. However during a complete heating/cooling cycle, the relation is highly non-linear. This can be explained by the fact that during cooling the temperature distribution is more uniform. Another problem to report is that TS is very sensitive to external movements

Anterior joint capsule of the normal hip and in children with transient synovitis: US study with anatomic and histologic correlation

PURPOSE: To study the anatomic components of the anterior joint capsule of the normal hip and in children with transient synovitis. MATERIALS AND METHODS: Six cadaveric specimens were imaged with ultrasonography (US) with special attention to the anterior joint capsule. Subsequently, two specimens were analyzed histologically. These anatomic findings were correlated with the US findings in 58 healthy children and 105 children with unilateral transient synovitis. RESULTS: The anterior joint capsule comprises an anterior and posterior layer, mainly composed of fibrous tissue, lined by only a minute synovial membrane. Both fibrous layers were identified separately at US in 98 of 116 (84%) hips of healthy subjects and in all hips with transient synovitis. Overall, the anterior layer was thicker than the posterior layer. In transient synovitis compared with normal hips, no significant thickening of both layers was present (P = .24 and .57 for the anterior and posterior layers, respectively). Normal variants include plicae, local thickening of the capsule, and pseudodiverticula. CONCLUSION: Increased thickness of the anterior joint capsule in transient synovitis is caused entirely by effusion. There is no US evidence for additional capsule swelling or synovial hypertrophy

Short-range correlations in two-nucleon knockout reactions

A theory of short-range correlations in two-nucleon removal due to elastic breakup (diffraction dissociation) on a light target is developed. Fingerprints of these correlations will appear in momentum distributions of back-to-back emission of the nucleon pair. Expressions for the momentum distributions are derived and calculations for reactions involving stable and unstable nuclear species are performed. The signature of short-range correlations in other reaction processes is also studied.Comment: Nuclear Physics A, in pres

Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort

STUDY FUNDING The data were collected by a Research into Ageing programme grant; research continues as part of the Age UK–funded Disconnected Mind project. The work was undertaken by The University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross-council Lifelong Health and Wellbeing Initiative (MR/K026992/1), with funding from the BBSRC and Medical Research Council. Imaging and image analysis was performed at the Brain Research Imaging Centre (sbirc.ed.ac.uk/), Edinburgh, supported by the Scottish Funding Council SINAPSE Collaboration. Derivation of mean cortical thickness measures was funded by the Scottish Funding Council’s Postdoctoral and Early Career Researchers Exchange Fund awarded by SINAPSE to David Alexander Dickie. L.C.A.C. acknowledges funding from the Scottish Government's Rural and Environment Science and Analytical Services (RESAS) division.Peer reviewedPublisher PD